Result of FASTA (omim) for
pFN21AB6641
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6641, 418 aa
1>>>pF1KB6641 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4105+/-0.000524; mu= -1.9143+/- 0.031
mean_var=539.5930+/-125.449, 0's: 0 Z-trim(117.0): 441 B-trim: 1740 in 1/55
Lambda= 0.055213
statistics sampled from 28106 (28689) to 28106 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.336), width: 16
Scan time: 8.500
The best scores are: opt bits E(85289)
NP_061041 (OMIM: 607333) STE20-related kinase adap ( 418) 2814 239.6 1.1e-62
NP_001193793 (OMIM: 607333) STE20-related kinase a ( 377) 2472 212.3 1.7e-54
XP_016859927 (OMIM: 607333) PREDICTED: STE20-relat ( 280) 1890 165.7 1.3e-40
XP_005246726 (OMIM: 607333) PREDICTED: STE20-relat ( 285) 1847 162.3 1.4e-39
NP_001003786 (OMIM: 608626,611087) STE20-related k ( 394) 1096 102.7 1.7e-21
XP_005257856 (OMIM: 608626,611087) PREDICTED: STE2 ( 373) 1095 102.6 1.7e-21
NP_001003788 (OMIM: 608626,611087) STE20-related k ( 373) 1095 102.6 1.7e-21
XP_011523769 (OMIM: 608626,611087) PREDICTED: STE2 ( 396) 1095 102.6 1.8e-21
XP_005257855 (OMIM: 608626,611087) PREDICTED: STE2 ( 402) 1095 102.6 1.8e-21
XP_005257854 (OMIM: 608626,611087) PREDICTED: STE2 ( 423) 1095 102.7 1.9e-21
NP_001003787 (OMIM: 608626,611087) STE20-related k ( 431) 1095 102.7 1.9e-21
XP_011523768 (OMIM: 608626,611087) PREDICTED: STE2 ( 403) 998 94.9 3.8e-19
NP_699166 (OMIM: 608626,611087) STE20-related kina ( 348) 995 94.6 4.2e-19
XP_016880801 (OMIM: 608626,611087) PREDICTED: STE2 ( 306) 907 87.5 5.1e-17
XP_016880802 (OMIM: 608626,611087) PREDICTED: STE2 ( 285) 906 87.4 5.2e-17
NP_001159441 (OMIM: 608626,611087) STE20-related k ( 314) 906 87.4 5.4e-17
XP_005257857 (OMIM: 608626,611087) PREDICTED: STE2 ( 343) 906 87.5 5.7e-17
NP_001159442 (OMIM: 608626,611087) STE20-related k ( 299) 890 86.1 1.3e-16
XP_016880803 (OMIM: 608626,611087) PREDICTED: STE2 ( 266) 815 80.1 7.6e-15
XP_005257858 (OMIM: 608626,611087) PREDICTED: STE2 ( 295) 815 80.1 8e-15
NP_005100 (OMIM: 604046) serine/threonine-protein ( 527) 414 48.6 4.4e-05
XP_016859305 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 393) 397 47.0 9.8e-05
XP_016859303 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 461) 397 47.1 0.00011
XP_005246522 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 524) 397 47.2 0.00011
XP_016859302 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 535) 397 47.2 0.00011
NP_037365 (OMIM: 607648) STE20/SPS1-related prolin ( 545) 397 47.3 0.00012
XP_005257860 (OMIM: 608626,611087) PREDICTED: STE2 ( 234) 388 46.0 0.00012
XP_016863090 (OMIM: 604046) PREDICTED: serine/thre ( 568) 387 46.5 0.00021
XP_011532633 (OMIM: 604046) PREDICTED: serine/thre ( 580) 387 46.5 0.00021
XP_016859304 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 443) 339 42.5 0.0026
NP_003609 (OMIM: 604921) mitogen-activated protein ( 894) 338 42.9 0.0039
NP_001077084 (OMIM: 610040) myosin-IIIb isoform 1 (1314) 341 43.4 0.004
XP_011508957 (OMIM: 610040) PREDICTED: myosin-IIIb (1323) 341 43.4 0.004
NP_620482 (OMIM: 610040) myosin-IIIb isoform 2 [Ho (1341) 341 43.4 0.0041
XP_006712362 (OMIM: 610040) PREDICTED: myosin-IIIb (1350) 341 43.4 0.0041
XP_011508956 (OMIM: 610040) PREDICTED: myosin-IIIb (1386) 341 43.4 0.0041
NP_056531 (OMIM: 609426) misshapen-like kinase 1 i (1295) 339 43.2 0.0045
NP_733763 (OMIM: 609426) misshapen-like kinase 1 i (1303) 339 43.2 0.0045
NP_001020108 (OMIM: 609426) misshapen-like kinase (1312) 339 43.2 0.0045
XP_016880195 (OMIM: 609426) PREDICTED: misshapen-l (1323) 339 43.2 0.0045
XP_006721599 (OMIM: 609426) PREDICTED: misshapen-l (1324) 339 43.2 0.0045
XP_011522208 (OMIM: 609426) PREDICTED: misshapen-l (1329) 339 43.3 0.0045
NP_722549 (OMIM: 609426) misshapen-like kinase 1 i (1332) 339 43.3 0.0045
XP_016880194 (OMIM: 609426) PREDICTED: misshapen-l (1341) 339 43.3 0.0045
XP_016880193 (OMIM: 609426) PREDICTED: misshapen-l (1358) 339 43.3 0.0046
XP_006721595 (OMIM: 609426) PREDICTED: misshapen-l (1360) 339 43.3 0.0046
XP_006721594 (OMIM: 609426) PREDICTED: misshapen-l (1361) 339 43.3 0.0046
NP_001155038 (OMIM: 610005,617028) TRAF2 and NCK-i (1268) 338 43.1 0.0047
NP_001155037 (OMIM: 610005,617028) TRAF2 and NCK-i (1276) 338 43.1 0.0047
NP_001155036 (OMIM: 610005,617028) TRAF2 and NCK-i (1297) 338 43.2 0.0047
>>NP_061041 (OMIM: 607333) STE20-related kinase adapter (418 aa)
initn: 2814 init1: 2814 opt: 2814 Z-score: 1246.3 bits: 239.6 E(85289): 1.1e-62
Smith-Waterman score: 2814; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KB6 MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPNIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQNGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQNGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 IHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 DLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSESR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 MKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSA
310 320 330 340 350 360
370 380 390 400 410
pF1KB6 SSLLSHVFFKQMKEESQDSILSLLPPAYNKPSISLPPVLPWTEPECDFPDEKDSYWEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SSLLSHVFFKQMKEESQDSILSLLPPAYNKPSISLPPVLPWTEPECDFPDEKDSYWEF
370 380 390 400 410
>>NP_001193793 (OMIM: 607333) STE20-related kinase adapt (377 aa)
initn: 2472 init1: 2472 opt: 2472 Z-score: 1099.5 bits: 212.3 E(85289): 1.7e-54
Smith-Waterman score: 2472; 100.0% identity (100.0% similar) in 371 aa overlap (1-371:1-371)
10 20 30 40 50 60
pF1KB6 MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPNIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQNGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQNGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 IHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 DLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSESR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 MKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSA
310 320 330 340 350 360
370 380 390 400 410
pF1KB6 SSLLSHVFFKQMKEESQDSILSLLPPAYNKPSISLPPVLPWTEPECDFPDEKDSYWEF
:::::::::::
NP_001 SSLLSHVFFKQPYFEFL
370
>>XP_016859927 (OMIM: 607333) PREDICTED: STE20-related k (280 aa)
initn: 1890 init1: 1890 opt: 1890 Z-score: 850.1 bits: 165.7 E(85289): 1.3e-40
Smith-Waterman score: 1890; 100.0% identity (100.0% similar) in 280 aa overlap (139-418:1-280)
110 120 130 140 150 160
pF1KB6 ILSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGA
::::::::::::::::::::::::::::::
XP_016 MAYGSASQLLRTYFPEGMSETLIRNILFGA
10 20 30
170 180 190 200 210 220
pF1KB6 VRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTS
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB6 VQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSP
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB6 LDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQL
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB6 CLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPAYNKPSISLPPVLPWTEPECDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPAYNKPSISLPPVLPWTEPECDF
220 230 240 250 260 270
410
pF1KB6 PDEKDSYWEF
::::::::::
XP_016 PDEKDSYWEF
280
>>XP_005246726 (OMIM: 607333) PREDICTED: STE20-related k (285 aa)
initn: 1869 init1: 1847 opt: 1847 Z-score: 831.5 bits: 162.3 E(85289): 1.4e-39
Smith-Waterman score: 1847; 99.6% identity (100.0% similar) in 276 aa overlap (1-276:1-276)
10 20 30 40 50 60
pF1KB6 MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPNIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQNGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQNGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 IHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 DLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSESR
:::::::::::::::::::::::::::::::::::.
XP_005 DLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQLGTALFATRS
250 260 270 280
310 320 330 340 350 360
pF1KB6 MKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSA
>>NP_001003786 (OMIM: 608626,611087) STE20-related kinas (394 aa)
initn: 1077 init1: 906 opt: 1096 Z-score: 506.9 bits: 102.7 E(85289): 1.7e-21
Smith-Waterman score: 1096; 48.7% identity (75.5% similar) in 359 aa overlap (30-386:3-359)
10 20 30 40 50
pF1KB6 MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCS--TNVSHY
.:... . : : : .::. : . . :
NP_001 MSFLTNDAS-SESIASFSKQEVMSSFLPEGGCY
10 20 30
60 70 80 90 100 110
pF1KB6 ELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPN
:: . ::.::..: .:.:::. ::: ::.. ::: :..: . :: . .:..: :::
NP_001 ELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQGELHVSKLFNHPN
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB6 ITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQN
:. : ..: . . :::.. :::::::..:. :.: .::.: : :: :....:.:.:.
NP_001 IVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQGVLKALDYIHHM
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB6 GCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELL
: .:::.:::::::: :: : :::: :...::::.:.:.:::..:..: ::::::.:
NP_001 GYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVHDFPKYSVKVLPWLSPEVL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 RQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSE
.:.:.::..:::::::::::::::.:.:::.:: :::::.::.: :: : .: :
NP_001 QQNLQGYDAKSDIYSVGITACELANGHVPFKDMPATQMLLEKLNGTVPCLLDTSTIPAEE
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB6 SRMKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQLCLQQDPEKRP
:. :.: ..::...: :..: . :.: : .:::: : .:. :::..:. ::
NP_001 LTMSPSRSVANSGLSDS-LTTSTPRPSNGDSPSHPYHRTFSPHFHHFVEQCLQRNPDARP
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB6 SASSLLSHVFFKQMKEESQDSILSLLPPAYNKPSISLPPVLPWTEPECDFPDEKDSYWEF
:::.::.: ::::.:....... :: :
NP_001 SASTLLNHSFFKQIKRRASEALPELLRPVTPITNFEGSQSQDHSGIFGLVTNLEELEVDD
340 350 360 370 380 390
>>XP_005257856 (OMIM: 608626,611087) PREDICTED: STE20-re (373 aa)
initn: 1077 init1: 906 opt: 1095 Z-score: 506.7 bits: 102.6 E(85289): 1.7e-21
Smith-Waterman score: 1095; 51.1% identity (77.5% similar) in 329 aa overlap (58-386:11-338)
30 40 50 60 70 80
pF1KB6 HQYLVDEPTLSWSRPSTRASEVLCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVT
::: . ::.::..: .:.:::. ::: ::
XP_005 MSSFLPEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVT
10 20 30 40
90 100 110 120 130 140
pF1KB6 IKITNLENCNEERLKALQKAVILSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQL
.. ::: :..: . :: . .:..: ::::. : ..: . . :::.. :::::::..:
XP_005 VRRINLEACSNEMVTFLQGELHVSKLFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDL
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB6 LRTYFPEGMSETLIRNILFGAVRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLH
. :.: .::.: : :: :....:.:.:. : .:::.:::::::: :: : ::::
XP_005 ICTHFMDGMNELAIAYILQGVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNL
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB6 SLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVP
:...::::.:.:.:::..:..: ::::::.:.:.:.::..:::::::::::::::.:.::
XP_005 SMISHGQRQRVVHDFPKYSVKVLPWLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVP
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB6 FQDMHRTQMLLQKLKGPPYSPLDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNS
:.:: :::::.::.: :: : .: : :. :.: ..::...: :..: . :.
XP_005 FKDMPATQMLLEKLNGTVPCLLDTSTIPAEELTMSPSRSVANSGLSDS-LTTSTPRPSNG
230 240 250 260 270
330 340 350 360 370 380
pF1KB6 DRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPA
: : .:::: : .:. :::..:. :::::.::.: ::::.:....... :: :
XP_005 DSPSHPYHRTFSPHFHHFVEQCLQRNPDARPSASTLLNHSFFKQIKRRASEALPELLRPV
280 290 300 310 320 330
390 400 410
pF1KB6 YNKPSISLPPVLPWTEPECDFPDEKDSYWEF
XP_005 TPITNFEGSQSQDHSGIFGLVTNLEELEVDDWEF
340 350 360 370
>>NP_001003788 (OMIM: 608626,611087) STE20-related kinas (373 aa)
initn: 1077 init1: 906 opt: 1095 Z-score: 506.7 bits: 102.6 E(85289): 1.7e-21
Smith-Waterman score: 1095; 51.1% identity (77.5% similar) in 329 aa overlap (58-386:11-338)
30 40 50 60 70 80
pF1KB6 HQYLVDEPTLSWSRPSTRASEVLCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVT
::: . ::.::..: .:.:::. ::: ::
NP_001 MSSFLPEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVT
10 20 30 40
90 100 110 120 130 140
pF1KB6 IKITNLENCNEERLKALQKAVILSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQL
.. ::: :..: . :: . .:..: ::::. : ..: . . :::.. :::::::..:
NP_001 VRRINLEACSNEMVTFLQGELHVSKLFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDL
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB6 LRTYFPEGMSETLIRNILFGAVRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLH
. :.: .::.: : :: :....:.:.:. : .:::.:::::::: :: : ::::
NP_001 ICTHFMDGMNELAIAYILQGVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNL
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB6 SLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVP
:...::::.:.:.:::..:..: ::::::.:.:.:.::..:::::::::::::::.:.::
NP_001 SMISHGQRQRVVHDFPKYSVKVLPWLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVP
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB6 FQDMHRTQMLLQKLKGPPYSPLDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNS
:.:: :::::.::.: :: : .: : :. :.: ..::...: :..: . :.
NP_001 FKDMPATQMLLEKLNGTVPCLLDTSTIPAEELTMSPSRSVANSGLSDS-LTTSTPRPSNG
230 240 250 260 270
330 340 350 360 370 380
pF1KB6 DRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPA
: : .:::: : .:. :::..:. :::::.::.: ::::.:....... :: :
NP_001 DSPSHPYHRTFSPHFHHFVEQCLQRNPDARPSASTLLNHSFFKQIKRRASEALPELLRPV
280 290 300 310 320 330
390 400 410
pF1KB6 YNKPSISLPPVLPWTEPECDFPDEKDSYWEF
NP_001 TPITNFEGSQSQDHSGIFGLVTNLEELEVDDWEF
340 350 360 370
>>XP_011523769 (OMIM: 608626,611087) PREDICTED: STE20-re (396 aa)
initn: 1077 init1: 906 opt: 1095 Z-score: 506.5 bits: 102.6 E(85289): 1.8e-21
Smith-Waterman score: 1095; 51.1% identity (77.5% similar) in 329 aa overlap (58-386:34-361)
30 40 50 60 70 80
pF1KB6 HQYLVDEPTLSWSRPSTRASEVLCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVT
::: . ::.::..: .:.:::. ::: ::
XP_011 IHQTNDASSESIASFSKQEVMSSFLPEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVT
10 20 30 40 50 60
90 100 110 120 130 140
pF1KB6 IKITNLENCNEERLKALQKAVILSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQL
.. ::: :..: . :: . .:..: ::::. : ..: . . :::.. :::::::..:
XP_011 VRRINLEACSNEMVTFLQGELHVSKLFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDL
70 80 90 100 110 120
150 160 170 180 190 200
pF1KB6 LRTYFPEGMSETLIRNILFGAVRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLH
. :.: .::.: : :: :....:.:.:. : .:::.:::::::: :: : ::::
XP_011 ICTHFMDGMNELAIAYILQGVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNL
130 140 150 160 170 180
210 220 230 240 250 260
pF1KB6 SLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVP
:...::::.:.:.:::..:..: ::::::.:.:.:.::..:::::::::::::::.:.::
XP_011 SMISHGQRQRVVHDFPKYSVKVLPWLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVP
190 200 210 220 230 240
270 280 290 300 310 320
pF1KB6 FQDMHRTQMLLQKLKGPPYSPLDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNS
:.:: :::::.::.: :: : .: : :. :.: ..::...: :..: . :.
XP_011 FKDMPATQMLLEKLNGTVPCLLDTSTIPAEELTMSPSRSVANSGLSDS-LTTSTPRPSNG
250 260 270 280 290 300
330 340 350 360 370 380
pF1KB6 DRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPA
: : .:::: : .:. :::..:. :::::.::.: ::::.:....... :: :
XP_011 DSPSHPYHRTFSPHFHHFVEQCLQRNPDARPSASTLLNHSFFKQIKRRASEALPELLRPV
310 320 330 340 350 360
390 400 410
pF1KB6 YNKPSISLPPVLPWTEPECDFPDEKDSYWEF
XP_011 TPITNFEGSQSQDHSGIFGLVTNLEELEVDDWEF
370 380 390
>>XP_005257855 (OMIM: 608626,611087) PREDICTED: STE20-re (402 aa)
initn: 1077 init1: 906 opt: 1095 Z-score: 506.4 bits: 102.6 E(85289): 1.8e-21
Smith-Waterman score: 1095; 51.1% identity (77.5% similar) in 329 aa overlap (58-386:40-367)
30 40 50 60 70 80
pF1KB6 HQYLVDEPTLSWSRPSTRASEVLCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVT
::: . ::.::..: .:.:::. ::: ::
XP_005 RIRTNDASSESIASFSKQEVMSSFLPEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVT
10 20 30 40 50 60
90 100 110 120 130 140
pF1KB6 IKITNLENCNEERLKALQKAVILSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQL
.. ::: :..: . :: . .:..: ::::. : ..: . . :::.. :::::::..:
XP_005 VRRINLEACSNEMVTFLQGELHVSKLFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDL
70 80 90 100 110 120
150 160 170 180 190 200
pF1KB6 LRTYFPEGMSETLIRNILFGAVRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLH
. :.: .::.: : :: :....:.:.:. : .:::.:::::::: :: : ::::
XP_005 ICTHFMDGMNELAIAYILQGVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNL
130 140 150 160 170 180
210 220 230 240 250 260
pF1KB6 SLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVP
:...::::.:.:.:::..:..: ::::::.:.:.:.::..:::::::::::::::.:.::
XP_005 SMISHGQRQRVVHDFPKYSVKVLPWLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVP
190 200 210 220 230 240
270 280 290 300 310 320
pF1KB6 FQDMHRTQMLLQKLKGPPYSPLDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNS
:.:: :::::.::.: :: : .: : :. :.: ..::...: :..: . :.
XP_005 FKDMPATQMLLEKLNGTVPCLLDTSTIPAEELTMSPSRSVANSGLSDS-LTTSTPRPSNG
250 260 270 280 290 300
330 340 350 360 370 380
pF1KB6 DRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPA
: : .:::: : .:. :::..:. :::::.::.: ::::.:....... :: :
XP_005 DSPSHPYHRTFSPHFHHFVEQCLQRNPDARPSASTLLNHSFFKQIKRRASEALPELLRPV
310 320 330 340 350 360
390 400 410
pF1KB6 YNKPSISLPPVLPWTEPECDFPDEKDSYWEF
XP_005 TPITNFEGSQSQDHSGIFGLVTNLEELEVDDWEF
370 380 390 400
>>XP_005257854 (OMIM: 608626,611087) PREDICTED: STE20-re (423 aa)
initn: 1077 init1: 906 opt: 1095 Z-score: 506.2 bits: 102.7 E(85289): 1.9e-21
Smith-Waterman score: 1095; 51.1% identity (77.5% similar) in 329 aa overlap (58-386:61-388)
30 40 50 60 70 80
pF1KB6 HQYLVDEPTLSWSRPSTRASEVLCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVT
::: . ::.::..: .:.:::. ::: ::
XP_005 RRKTNDASSESIASFSKQEVMSSFLPEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVT
40 50 60 70 80 90
90 100 110 120 130 140
pF1KB6 IKITNLENCNEERLKALQKAVILSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQL
.. ::: :..: . :: . .:..: ::::. : ..: . . :::.. :::::::..:
XP_005 VRRINLEACSNEMVTFLQGELHVSKLFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDL
100 110 120 130 140 150
150 160 170 180 190 200
pF1KB6 LRTYFPEGMSETLIRNILFGAVRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLH
. :.: .::.: : :: :....:.:.:. : .:::.:::::::: :: : ::::
XP_005 ICTHFMDGMNELAIAYILQGVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNL
160 170 180 190 200 210
210 220 230 240 250 260
pF1KB6 SLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVP
:...::::.:.:.:::..:..: ::::::.:.:.:.::..:::::::::::::::.:.::
XP_005 SMISHGQRQRVVHDFPKYSVKVLPWLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVP
220 230 240 250 260 270
270 280 290 300 310 320
pF1KB6 FQDMHRTQMLLQKLKGPPYSPLDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNS
:.:: :::::.::.: :: : .: : :. :.: ..::...: :..: . :.
XP_005 FKDMPATQMLLEKLNGTVPCLLDTSTIPAEELTMSPSRSVANSGLSDS-LTTSTPRPSNG
280 290 300 310 320
330 340 350 360 370 380
pF1KB6 DRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPA
: : .:::: : .:. :::..:. :::::.::.: ::::.:....... :: :
XP_005 DSPSHPYHRTFSPHFHHFVEQCLQRNPDARPSASTLLNHSFFKQIKRRASEALPELLRPV
330 340 350 360 370 380
390 400 410
pF1KB6 YNKPSISLPPVLPWTEPECDFPDEKDSYWEF
XP_005 TPITNFEGSQSQDHSGIFGLVTNLEELEVDDWEF
390 400 410 420
418 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:08:26 2016 done: Sun Nov 6 18:08:27 2016
Total Scan time: 8.500 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]