Result of FASTA (omim) for
pFN21AB6554
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6554, 391 aa
1>>>pF1KB6554 391 - 391 aa - 391 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8276+/-0.000565; mu= -2.9820+/- 0.034
mean_var=574.9372+/-128.922, 0's: 0 Z-trim(116.8): 1068 B-trim: 565 in 1/53
Lambda= 0.053489
statistics sampled from 26803 (28265) to 26803 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.331), width: 16
Scan time: 8.120
The best scores are: opt bits E(85289)
NP_001886 (OMIM: 115440,617062) casein kinase II s ( 391) 2661 220.7 4.8e-57
NP_808227 (OMIM: 115440,617062) casein kinase II s ( 391) 2661 220.7 4.8e-57
NP_001887 (OMIM: 115442) casein kinase II subunit ( 350) 1980 168.1 3e-41
NP_808228 (OMIM: 115440,617062) casein kinase II s ( 255) 1760 150.9 3.2e-36
XP_005255857 (OMIM: 115442) PREDICTED: casein kina ( 299) 1323 117.3 5e-26
XP_005255858 (OMIM: 115442) PREDICTED: casein kina ( 213) 1226 109.5 7.5e-24
XP_016878434 (OMIM: 115442) PREDICTED: casein kina ( 242) 1198 107.5 3.6e-23
NP_002742 (OMIM: 602898) mitogen-activated protein ( 364) 495 53.5 9.5e-07
NP_002960 (OMIM: 602399) mitogen-activated protein ( 367) 492 53.3 1.1e-06
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 464 51.0 4.5e-06
XP_011509952 (OMIM: 616147) PREDICTED: cyclin-depe ( 412) 467 51.4 4.5e-06
XP_005246839 (OMIM: 616147) PREDICTED: cyclin-depe ( 384) 465 51.2 4.9e-06
NP_631897 (OMIM: 616147) cyclin-dependent kinase 1 ( 384) 465 51.2 4.9e-06
NP_001248365 (OMIM: 616147) cyclin-dependent kinas ( 400) 465 51.3 5e-06
NP_001248364 (OMIM: 616147) cyclin-dependent kinas ( 429) 465 51.3 5.2e-06
XP_005246838 (OMIM: 616147) PREDICTED: cyclin-depe ( 435) 465 51.3 5.2e-06
NP_001274065 (OMIM: 610679) cyclin-dependent kinas ( 423) 464 51.2 5.4e-06
XP_005250496 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 464 51.2 5.4e-06
XP_016867810 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 464 51.2 5.4e-06
XP_016867809 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 464 51.2 5.4e-06
XP_005250495 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 464 51.2 5.4e-06
XP_016867811 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 464 51.2 5.4e-06
XP_005250493 (OMIM: 610679) PREDICTED: cyclin-depe ( 450) 464 51.3 5.6e-06
NP_036527 (OMIM: 610679) cyclin-dependent kinase 1 ( 451) 464 51.3 5.6e-06
NP_001274064 (OMIM: 610679) cyclin-dependent kinas ( 469) 464 51.3 5.7e-06
XP_011514608 (OMIM: 610679) PREDICTED: cyclin-depe ( 469) 464 51.3 5.7e-06
NP_001034892 (OMIM: 610076) cyclin-dependent kinas ( 346) 458 50.6 6.7e-06
XP_016885062 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 458 50.9 8.1e-06
XP_016885061 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 458 50.9 8.1e-06
NP_006192 (OMIM: 311550) cyclin-dependent kinase 1 ( 496) 458 50.9 8.1e-06
XP_016885059 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 458 50.9 8.1e-06
XP_016885060 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 458 50.9 8.1e-06
XP_011542226 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 458 50.9 8.1e-06
XP_011542229 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 458 50.9 8.1e-06
XP_011542228 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 458 50.9 8.1e-06
XP_011542227 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 458 50.9 8.1e-06
XP_011542230 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 458 50.9 8.1e-06
NP_148978 (OMIM: 311550) cyclin-dependent kinase 1 ( 502) 458 50.9 8.2e-06
XP_011542225 (OMIM: 311550) PREDICTED: cyclin-depe ( 503) 458 50.9 8.2e-06
XP_005268214 (OMIM: 603441) PREDICTED: cyclin-depe ( 358) 454 50.3 8.5e-06
XP_016877218 (OMIM: 603441) PREDICTED: cyclin-depe ( 358) 454 50.3 8.5e-06
NP_004187 (OMIM: 603441) cyclin-dependent kinase-l ( 358) 454 50.3 8.5e-06
XP_011542224 (OMIM: 311550) PREDICTED: cyclin-depe ( 540) 458 50.9 8.5e-06
XP_016885058 (OMIM: 311550) PREDICTED: cyclin-depe ( 543) 458 50.9 8.5e-06
XP_011542223 (OMIM: 311550) PREDICTED: cyclin-depe ( 544) 458 50.9 8.5e-06
NP_001163931 (OMIM: 311550) cyclin-dependent kinas ( 570) 458 51.0 8.7e-06
XP_011542222 (OMIM: 311550) PREDICTED: cyclin-depe ( 571) 458 51.0 8.7e-06
NP_620407 (OMIM: 176948) mitogen-activated protein ( 360) 452 50.2 9.4e-06
NP_002736 (OMIM: 176948) mitogen-activated protein ( 360) 452 50.2 9.4e-06
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 451 50.4 1.2e-05
>>NP_001886 (OMIM: 115440,617062) casein kinase II subun (391 aa)
initn: 2661 init1: 2661 opt: 2661 Z-score: 1145.2 bits: 220.7 E(85289): 4.8e-57
Smith-Waterman score: 2661; 100.0% identity (100.0% similar) in 391 aa overlap (1-391:1-391)
10 20 30 40 50 60
pF1KB6 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPT
310 320 330 340 350 360
370 380 390
pF1KB6 PSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
:::::::::::::::::::::::::::::::
NP_001 PSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
370 380 390
>>NP_808227 (OMIM: 115440,617062) casein kinase II subun (391 aa)
initn: 2661 init1: 2661 opt: 2661 Z-score: 1145.2 bits: 220.7 E(85289): 4.8e-57
Smith-Waterman score: 2661; 100.0% identity (100.0% similar) in 391 aa overlap (1-391:1-391)
10 20 30 40 50 60
pF1KB6 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 QLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPT
310 320 330 340 350 360
370 380 390
pF1KB6 PSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
:::::::::::::::::::::::::::::::
NP_808 PSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
370 380 390
>>NP_001887 (OMIM: 115442) casein kinase II subunit alph (350 aa)
initn: 1969 init1: 1969 opt: 1980 Z-score: 861.6 bits: 168.1 E(85289): 3e-41
Smith-Waterman score: 1980; 85.3% identity (94.9% similar) in 334 aa overlap (1-333:1-334)
10 20 30 40 50
pF1KB6 MSGPVP-SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINI
: ::. ::::::..::. : :::::::.:: :::::::::::::::::::::::::::
NP_001 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 TNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNT
::::.:::::::::::::::::.::::::::: ::: : : ::::::.:::::::..:::
NP_001 TNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 DFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA
::::::: :::.::::::::.::::::::: ::::::::::::::::...::::::::::
NP_001 DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 EFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNY
:::::.:::::::::::::::::::::::::::::::::::::::::::.::::::.:::
NP_001 EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 DQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALD
:::::::::::::.:: :. ::.:.:::.::::::.::::::: :.::::.:::::::::
NP_001 DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 FLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVP
.::::::::::.::::.::::::::: :::.:..
NP_001 LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
310 320 330 340 350
360 370 380 390
pF1KB6 TPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
>>NP_808228 (OMIM: 115440,617062) casein kinase II subun (255 aa)
initn: 1760 init1: 1760 opt: 1760 Z-score: 771.2 bits: 150.9 E(85289): 3.2e-36
Smith-Waterman score: 1760; 100.0% identity (100.0% similar) in 255 aa overlap (137-391:1-255)
110 120 130 140 150 160
pF1KB6 RTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH
::::::::::::::::::::::::::::::
NP_808 MYEILKALDYCHSMGIMHRDVKPHNVMIDH
10 20 30
170 180 190 200 210 220
pF1KB6 EHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 EHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMI
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB6 FRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 FRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVH
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB6 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPV
160 170 180 190 200 210
350 360 370 380 390
pF1KB6 SSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
:::::::::::::::::::::::::::::::::::::::::::::
NP_808 SSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
220 230 240 250
>>XP_005255857 (OMIM: 115442) PREDICTED: casein kinase I (299 aa)
initn: 1678 init1: 1316 opt: 1323 Z-score: 588.3 bits: 117.3 E(85289): 5e-26
Smith-Waterman score: 1585; 72.5% identity (80.8% similar) in 334 aa overlap (1-333:1-283)
10 20 30 40 50
pF1KB6 MSGPVP-SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINI
: ::. ::::::..::. : :::::::.:: :::::::::::::::::::::::::::
XP_005 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 TNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNT
::::.:::::::
XP_005 TNNERVVVKILK------------------------------------------------
70
120 130 140 150 160 170
pF1KB6 DFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA
:::: :::.::::::::.::::::::: ::::::::::::::::...::::::::::
XP_005 ---QLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
80 90 100 110 120
180 190 200 210 220 230
pF1KB6 EFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNY
:::::.:::::::::::::::::::::::::::::::::::::::::::.::::::.:::
XP_005 EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
130 140 150 160 170 180
240 250 260 270 280 290
pF1KB6 DQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALD
:::::::::::::.:: :. ::.:.:::.::::::.::::::: :.::::.:::::::::
XP_005 DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB6 FLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVP
.::::::::::.::::.::::::::: :::.:..
XP_005 LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
250 260 270 280 290
360 370 380 390
pF1KB6 TPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
>>XP_005255858 (OMIM: 115442) PREDICTED: casein kinase I (213 aa)
initn: 1226 init1: 1226 opt: 1226 Z-score: 549.2 bits: 109.5 E(85289): 7.5e-24
Smith-Waterman score: 1226; 86.8% identity (97.5% similar) in 197 aa overlap (137-333:1-197)
110 120 130 140 150 160
pF1KB6 RTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH
:::.::::::::: ::::::::::::::::
XP_005 MYELLKALDYCHSKGIMHRDVKPHNVMIDH
10 20 30
170 180 190 200 210 220
pF1KB6 EHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMI
...:::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_005 QQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMI
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB6 FRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVH
::.::::::.::::::::::::::::.:: :. ::.:.:::.::::::.::::::: :.:
XP_005 FRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIH
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB6 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPV
:::.:::::::::.::::::::::.::::.::::::::: :::.:..
XP_005 SENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLT
160 170 180 190 200 210
350 360 370 380 390
pF1KB6 SSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
XP_005 AAR
>>XP_016878434 (OMIM: 115442) PREDICTED: casein kinase I (242 aa)
initn: 1198 init1: 1198 opt: 1198 Z-score: 537.0 bits: 107.5 E(85289): 3.6e-23
Smith-Waterman score: 1198; 87.0% identity (97.4% similar) in 192 aa overlap (142-333:35-226)
120 130 140 150 160 170
pF1KB6 VFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKL
:::::::: ::::::::::::::::...::
XP_016 NPNVHQLVVEYYSARKNNLDESQKQYTEGKKALDYCHSKGIMHRDVKPHNVMIDHQQKKL
10 20 30 40 50 60
180 190 200 210 220 230
pF1KB6 RLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEP
:::::::::::::.:::::::::::::::::::::::::::::::::::::::::::.::
XP_016 RLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREP
70 80 90 100 110 120
240 250 260 270 280 290
pF1KB6 FFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQH
::::.::::::::::::::::.:: :. ::.:.:::.::::::.::::::: :.::::.:
XP_016 FFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRH
130 140 150 160 170 180
300 310 320 330 340 350
pF1KB6 LVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANM
::::::::.::::::::::.::::.::::::::: :::.:..
XP_016 LVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
190 200 210 220 230 240
360 370 380 390
pF1KB6 MSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
>>NP_002742 (OMIM: 602898) mitogen-activated protein kin (364 aa)
initn: 206 init1: 131 opt: 495 Z-score: 242.1 bits: 53.5 E(85289): 9.5e-07
Smith-Waterman score: 495; 30.1% identity (62.0% similar) in 316 aa overlap (20-324:4-308)
10 20 30 40 50
pF1KB6 MSGPVPSRARVYTDVNTHRPRE-YWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINI
:: .. : . . : . : .: .: : :. : : .
NP_002 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDA
10 20 30 40
60 70 80 90 100 110
pF1KB6 TNNEKVVVKIL-KP----VKKKKIKREIKILENLRGGPNIITLADIVKDPVS---RTPAL
.::.:: : .: .. .. ::...:..:. :.: : :. .: . .
NP_002 RLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKH-ENVIGLLDVFTPATSIEDFSEVY
50 60 70 80 90 100
120 130 140 150 160
pF1KB6 VFEHVNNTDFKQLY--QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHR
. . ..:.... :.:.: ..: .:..:..: : :: ::.:::.:: :: .. :
NP_002 LVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVN-EDC
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 KLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRK
.::..:.:::. . .:.. ::.:....::...... :. ..:.::.::..: .. .
NP_002 ELRILDFGLAR--QADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELL-QG
170 180 190 200 210
230 240 250 260 270 280
pF1KB6 EPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSEN
. .: : : ::: :: .:.:: . . . : . : . . : .: . .. :
NP_002 KALFPGSDYIDQLKRIMEVVGTPS-PEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGAN
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB6 QHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSA
: :.:.: ..: : ..:..: ::. : ::
NP_002 -----PLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAKERT
280 290 300 310 320 330
350 360 370 380 390
pF1KB6 NMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
NP_002 LEEWKELTYQEVLSFKPPEPPKPPGSLEIEQ
340 350 360
>>NP_002960 (OMIM: 602399) mitogen-activated protein kin (367 aa)
initn: 364 init1: 127 opt: 492 Z-score: 240.8 bits: 53.3 E(85289): 1.1e-06
Smith-Waterman score: 492; 30.3% identity (61.7% similar) in 337 aa overlap (1-327:1-314)
10 20 30 40 50 60
pF1KB6 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
::.: :.:. : . : . : : ..: :. .. .: : :. : :..
NP_002 MSSPPPARSGFYRQEVT---KTAW--EVRAV-------YRDLQPVGSGAYGAVCSAVDGR
10 20 30 40
70 80 90 100 110
pF1KB6 NNEKVVVKIL-KPVKK----KKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEH
.. ::..: : .: .. :. ::...:...: :.: : :. . :
NP_002 TGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRH-ENVIGLLDVFTPDETLDDFTDFYL
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 VN---NTDFKQL--YQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRK
: .::. .: .. : . :.: .:..::.: : :. ::.:::.:: :. .. : .
NP_002 VMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVN-EDCE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 LRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKE
:...:.:::. . .:.. :..:....::...... : ..:.::.::..: :: :
NP_002 LKILDFGLAR--QADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKT
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 PFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQ
.:.: :. ::: .: :: :: ..... . . . : . .: . .. .
NP_002 -LFKGSDHLDQLKEIMKVTGTPPA-EFVQRLQSDEAKNYMKGLPELEKKDFASILTN---
230 240 250 260 270
300 310 320 330 340 350
pF1KB6 HLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSAN
.:: :...:.:.: : ..:.:: ::. :::: ..
NP_002 --ASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFESLHDTEDEPQVQKYDDSFDDVDRTL
280 290 300 310 320 330
360 370 380 390
pF1KB6 MMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
NP_002 DEWKRVTYKEVLSFKPPRQLGARVSKETPL
340 350 360
>>NP_004926 (OMIM: 123831,616342) cyclin-dependent-like (292 aa)
initn: 361 init1: 286 opt: 464 Z-score: 230.1 bits: 51.0 E(85289): 4.5e-06
Smith-Waterman score: 464; 31.1% identity (64.9% similar) in 299 aa overlap (39-324:4-286)
10 20 30 40 50 60
pF1KB6 ARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVK
:. ..:.:.: :. ::.: : ..: :..:
NP_004 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALK
10 20 30
70 80 90 100 110 120
pF1KB6 ILK------PVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFK
.. : .. . ::: .:..:. ::. : :.... .. .:::: .. :.:
NP_004 RVRLDDDDEGVPSSAL-REICLLKELKH-KNIVRLHDVLHS--DKKLTLVFEFCDQ-DLK
40 50 60 70 80
130 140 150 160 170
pF1KB6 QLYQTLT-DYD---IRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL
. ... . : : .. .....::.: .::: ...:::.::.:..:.. . .:.: :.::
NP_004 KYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINR-NGELKLADFGL
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB6 AE-FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHD
:. : : . :...:.. ... :..: ..:. :.:::: ::..: . .:.: :.:
NP_004 ARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGND
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB6 NYDQLVRIAKVLGT--EDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSP
::: :: ..::: :. . . : : .. . : . :
NP_004 VDDQLKRIFRLLGTPTEEQWPSMTKL-----PDYKPYPMYPATTSLVNVVPKLNA-----
210 220 230 240 250
300 310 320 330 340 350
pF1KB6 EALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGI
. :.:..::. . .:..:.::..::::
NP_004 TGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
260 270 280 290
391 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:50:05 2016 done: Mon Nov 7 01:50:06 2016
Total Scan time: 8.120 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]