Result of FASTA (ccds) for
pFN21AB6536
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6536, 390 aa
1>>>pF1KB6536 390 - 390 aa - 390 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0992+/-0.00117; mu= 7.9796+/- 0.070
mean_var=166.7809+/-55.523, 0's: 0 Z-trim(104.9): 236 B-trim: 1034 in 2/47
Lambda= 0.099312
statistics sampled from 7775 (8157) to 7775 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.251), width: 16
Scan time: 2.350
The best scores are: opt bits E(32554)
CCDS11887.1 HRH4 gene_id:59340|Hs108|chr18 ( 390) 2584 383.1 2.4e-106
CCDS45841.1 HRH4 gene_id:59340|Hs108|chr18 ( 302) 1612 243.7 1.7e-64
CCDS13493.1 HRH3 gene_id:11255|Hs108|chr20 ( 445) 635 103.9 3e-22
CCDS1616.1 CHRM3 gene_id:1131|Hs108|chr1 ( 590) 417 72.8 9.4e-13
CCDS10031.1 CHRM5 gene_id:1133|Hs108|chr15 ( 532) 379 67.3 3.8e-11
CCDS5843.1 CHRM2 gene_id:1129|Hs108|chr7 ( 466) 369 65.8 9.4e-11
>>CCDS11887.1 HRH4 gene_id:59340|Hs108|chr18 (390 aa)
initn: 2584 init1: 2584 opt: 2584 Z-score: 2022.7 bits: 383.1 E(32554): 2.4e-106
Smith-Waterman score: 2584; 100.0% identity (100.0% similar) in 390 aa overlap (1-390:1-390)
10 20 30 40 50 60
pF1KB6 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DFFVGVISIPLYIPHTLFEWDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSVSNAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DFFVGVISIPLYIPHTLFEWDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSVSNAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEGSECEPGFFSEWYILAITSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEGSECEPGFFSEWYILAITSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 STEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 STEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPL
310 320 330 340 350 360
370 380 390
pF1KB6 CHKRFQKAFLKIFCIKKQPLPSQHSRSVSS
::::::::::::::::::::::::::::::
CCDS11 CHKRFQKAFLKIFCIKKQPLPSQHSRSVSS
370 380 390
>>CCDS45841.1 HRH4 gene_id:59340|Hs108|chr18 (302 aa)
initn: 1612 init1: 1612 opt: 1612 Z-score: 1271.4 bits: 243.7 E(32554): 1.7e-64
Smith-Waterman score: 1816; 77.4% identity (77.4% similar) in 390 aa overlap (1-390:1-302)
10 20 30 40 50 60
pF1KB6 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DFFVGVISIPLYIPHTLFEWDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSVSNAV
::::
CCDS45 DFFV--------------------------------------------------------
130 140 150 160 170 180
pF1KB6 SYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEGSECEPGFFSEWYILAITSF
::::::::::::::::::::::::::::
CCDS45 --------------------------------VSESWKDEGSECEPGFFSEWYILAITSF
70 80 90
190 200 210 220 230 240
pF1KB6 LEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSA
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB6 STEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 STEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRARR
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB6 LAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPL
220 230 240 250 260 270
370 380 390
pF1KB6 CHKRFQKAFLKIFCIKKQPLPSQHSRSVSS
::::::::::::::::::::::::::::::
CCDS45 CHKRFQKAFLKIFCIKKQPLPSQHSRSVSS
280 290 300
>>CCDS13493.1 HRH3 gene_id:11255|Hs108|chr20 (445 aa)
initn: 961 init1: 312 opt: 635 Z-score: 512.8 bits: 103.9 E(32554): 3e-22
Smith-Waterman score: 896; 39.5% identity (63.6% similar) in 423 aa overlap (10-382:29-439)
10 20 30 40
pF1KB6 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFV
.: . ..:: .:.:. : .::::::.::::
CCDS13 MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 VDKNLRHRSSYFFLNLAISDFFVGVISIPLYIPHTLF-EWDFGKEICVFWLTTDYLLCTA
.:..:: ....:.::::::::.::.. ::::.:..: .: ::. .: .::..::::::.
CCDS13 ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
70 80 90 100 110 120
110 120 130 140 150
pF1KB6 SVYNIVLISYDRYLSVSNAVSYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWK--
:..:::::::::.:::. :::::.:. . . : :. :::::::. :: :: ::.
CCDS13 SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAIL---SWEYL
130 140 150 160 170
160 170 180 190
pF1KB6 DEGS-----ECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIY---------------
. :: .: :: .::.: .: ::: : . :..::..::
CCDS13 SGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAR
180 190 200 210 220 230
200 210 220 230
pF1KB6 ---------------------WSLWKRDHLSRCQSHP---GLTAVSSNICGHSFRGRLSS
:. :.. : : : .::... :.. : ..
CCDS13 EAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEA-GEATLGGGGG
240 250 260 270 280 290
240 250 260 270 280 290
pF1KB6 RRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVE
:... : .: :. .: :: .:. . .: .. ..: ::: . :: .
CCDS13 GGSVASPTSSSGS-SSRGTERPRSLKRGSKPSASSASLEKRMKMVSQS----FTQR--FR
300 310 320 330 340
300 310 320 330 340 350
pF1KB6 LLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVN
: : :..:::::.....:..:::::.:. :. . . : . ::. .::: : :: ::
CCDS13 LSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVP-DYWYETSFWLLWANSAVN
350 360 370 380 390 400
360 370 380 390
pF1KB6 PLLYPLCHKRFQKAFLKIFCIKK---QPLPSQHSRSVSS
:.::::::. :..:: :..: .: :: :
CCDS13 PVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWK
410 420 430 440
>>CCDS1616.1 CHRM3 gene_id:1131|Hs108|chr1 (590 aa)
initn: 449 init1: 162 opt: 417 Z-score: 342.4 bits: 72.8 E(32554): 9.4e-13
Smith-Waterman score: 417; 30.6% identity (65.5% similar) in 278 aa overlap (16-284:69-336)
10 20 30 40
pF1KB6 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKN
: .::. ...:.. ..:: :::..: :.:.
CCDS16 SYNVSRAAGNFSSPDGTTDDPLGGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQ
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB6 LRHRSSYFFLNLAISDFFVGVISIPLYIPHTLFE-WDFGKEICVFWLTTDYLLCTASVYN
:. ..::.:.:: .:...::::. :. . ... : .:. : .::. ::. .:::.:
CCDS16 LKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMN
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB6 IVLISYDRYLSVSNAVSYRTQHTGVLKIVTLMVAV-WVLAFLVNGPMILVSESWKDEGS-
...::.:::.:.. ..::...: : . .:... ::..:.. .: :: . . . .
CCDS16 LLVISFDRYFSITRPLTYRAKRT--TKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTV
160 170 180 190 200 210
170 180 190 200 210
pF1KB6 ---ECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAV
:: :.:: : :.. : .:: ... .:: ..:. . .: . :: :
CCDS16 PPGECFIQFLSEPTITFGTAIAAFYMPVTIMTI----LYWRIYKETE-KRTKELAGLQAS
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB6 SSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSS---LMFSSRTKMNSNTIASKM
... ..: .: :: : : :. . .. .::: . . :.... :. ..
CCDS16 GTEAETENFVHPTGSSRSCS-SYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQ-
280 290 300 310 320
280 290 300 310 320 330
pF1KB6 GSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPK
. :.:::
CCDS16 -DHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDN
330 340 350 360 370 380
>>CCDS10031.1 CHRM5 gene_id:1133|Hs108|chr15 (532 aa)
initn: 417 init1: 159 opt: 379 Z-score: 313.6 bits: 67.3 E(32554): 3.8e-11
Smith-Waterman score: 379; 29.8% identity (63.8% similar) in 265 aa overlap (16-270:31-293)
10 20 30 40
pF1KB6 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKN
.:.: ..:.. ..::.::...: :...
CCDS10 MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 LRHRSSYFFLNLAISDFFVGVISIPLYIPHTLF-EWDFGKEICVFWLTTDYLLCTASVYN
:. ..:..:.:: .:...:..:. :: . :. .: .:. : .::. ::. .:::.:
CCDS10 LKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMN
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 IVLISYDRYLSVSNAVSYRTQHTGVLKIVTLMVAV-WVLAFLVNGPMILVSESWKDEGS-
...::.:::.:.. ..::...: : . .:... :...:.. .: :: . . .
CCDS10 LLVISFDRYFSITRPLTYRAKRTP--KRAGIMIGLAWLISFILWAPAILCWQYLVGKRTV
130 140 150 160 170
170 180 190 200 210
pF1KB6 ---ECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDH-LSRCQSHPGLTA
::. :.:: : :.. : ::: ... . :: :: . :. :. ..:
CCDS10 PLDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTK
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 VSSNICGHS--FRGRLSSRRSLSASTEV-PASFHSERQRRKSSLMFSSRTKMNSNTIASK
. . .: ::. : : :. : ::. : :. ... :. : ..:
CCDS10 AEKRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAE
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 MGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGP
CCDS10 QLTTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDT
300 310 320 330 340 350
>>CCDS5843.1 CHRM2 gene_id:1129|Hs108|chr7 (466 aa)
initn: 408 init1: 121 opt: 369 Z-score: 306.6 bits: 65.8 E(32554): 9.4e-11
Smith-Waterman score: 369; 29.6% identity (65.8% similar) in 243 aa overlap (4-232:8-240)
10 20 30 40 50
pF1KB6 MPDTNSTINLSLSTRVTLAFFMSLVA----FAIMLGNALVILAFVVDKNLRHRSSY
.:... :. .. . :. ::: .. ..:: ::.... :...:. ..:
CCDS58 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 FFLNLAISDFFVGVISIPLYIPHTLF-EWDFGKEICVFWLTTDYLLCTASVYNIVLISYD
:...:: .:...::.:. :: .:.. : .: .: .::. ::.. .:::.:...::.:
CCDS58 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
70 80 90 100 110 120
120 130 140 150 160
pF1KB6 RYLSVSNAVSYRTQHTGVLKIVTLMVAV-WVLAFLVNGPMILVSESWK-------DEGSE
::. :.. ..: ...: :.. .:.:. :::.:.. .: :: :. : .:
CCDS58 RYFCVTKPLTYPVKRT--TKMAGMMIAAAWVLSFILWAPAILF---WQFIVGVRTVEDGE
130 140 150 160 170
170 180 190 200 210 220
pF1KB6 CEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNI
: :::. . :.. : .:::... .:: . .: :: .. .....
CCDS58 CYIQFFSNAAVTFGTAIAAFYLPVIIMTV----LYWHI-SRASKSRIKKDKKEPVANQDP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 CGHSF-RGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQS
. :. .::.
CCDS58 VSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVS
240 250 260 270 280 290
390 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:00:56 2016 done: Mon Nov 7 16:00:57 2016
Total Scan time: 2.350 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]