Result of FASTA (omim) for
pFN21AB6261
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6261, 686 aa
1>>>pF1KB6261 686 - 686 aa - 686 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8577+/-0.000556; mu= -0.9056+/- 0.034
mean_var=701.2955+/-158.038, 0's: 0 Z-trim(115.5): 1679 B-trim: 0 in 0/57
Lambda= 0.048431
statistics sampled from 23702 (26006) to 23702 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.305), width: 16
Scan time: 9.070
The best scores are: opt bits E(85289)
NP_006249 (OMIM: 176894,615436) cGMP-dependent pro ( 686) 4552 335.0 5.7e-91
NP_001091982 (OMIM: 176894,615436) cGMP-dependent ( 671) 3966 294.0 1.2e-78
XP_016871901 (OMIM: 176894,615436) PREDICTED: cGMP ( 591) 3900 289.3 2.7e-77
XP_016871902 (OMIM: 176894,615436) PREDICTED: cGMP ( 585) 3890 288.6 4.4e-77
XP_011538254 (OMIM: 176894,615436) PREDICTED: cGMP ( 406) 2330 179.4 2.4e-44
NP_001269414 (OMIM: 601591) cGMP-dependent protein ( 733) 2189 170.0 3e-41
XP_016863906 (OMIM: 601591) PREDICTED: cGMP-depend ( 745) 2087 162.8 4.2e-39
NP_001269409 (OMIM: 601591) cGMP-dependent protein ( 342) 1492 120.7 9.4e-27
NP_001269410 (OMIM: 601591) cGMP-dependent protein ( 342) 1492 120.7 9.4e-27
XP_005263183 (OMIM: 601591) PREDICTED: cGMP-depend ( 762) 1492 121.3 1.4e-26
NP_006250 (OMIM: 601591) cGMP-dependent protein ki ( 762) 1492 121.3 1.4e-26
NP_001269411 (OMIM: 601591) cGMP-dependent protein ( 313) 1403 114.4 6.7e-25
XP_016863903 (OMIM: 601591) PREDICTED: cGMP-depend ( 774) 1390 114.2 1.9e-24
XP_016863902 (OMIM: 601591) PREDICTED: cGMP-depend ( 774) 1390 114.2 1.9e-24
XP_016863905 (OMIM: 601591) PREDICTED: cGMP-depend ( 774) 1390 114.2 1.9e-24
XP_016863904 (OMIM: 601591) PREDICTED: cGMP-depend ( 774) 1390 114.2 1.9e-24
NP_001269412 (OMIM: 601591) cGMP-dependent protein ( 282) 1374 112.3 2.6e-24
NP_005035 (OMIM: 300083) cAMP-dependent protein ki ( 358) 1000 86.3 2.1e-16
NP_001229787 (OMIM: 176892) cAMP-dependent protein ( 339) 956 83.2 1.8e-15
XP_005271073 (OMIM: 176892) PREDICTED: cAMP-depend ( 349) 953 83.0 2.1e-15
XP_005271072 (OMIM: 176892) PREDICTED: cAMP-depend ( 350) 953 83.0 2.1e-15
NP_001229789 (OMIM: 176892) cAMP-dependent protein ( 357) 953 83.1 2.1e-15
NP_001229786 (OMIM: 176892) cAMP-dependent protein ( 358) 953 83.1 2.1e-15
XP_005271075 (OMIM: 176892) PREDICTED: cAMP-depend ( 346) 951 82.9 2.3e-15
XP_005271074 (OMIM: 176892) PREDICTED: cAMP-depend ( 347) 951 82.9 2.3e-15
XP_006710821 (OMIM: 176892) PREDICTED: cAMP-depend ( 354) 951 82.9 2.3e-15
NP_001229788 (OMIM: 176892) cAMP-dependent protein ( 355) 951 82.9 2.3e-15
NP_891993 (OMIM: 176892) cAMP-dependent protein ki ( 398) 951 83.0 2.4e-15
XP_005271076 (OMIM: 176892) PREDICTED: cAMP-depend ( 338) 949 82.7 2.5e-15
NP_001229791 (OMIM: 176892) cAMP-dependent protein ( 338) 949 82.7 2.5e-15
NP_002722 (OMIM: 176892) cAMP-dependent protein ki ( 351) 949 82.8 2.5e-15
NP_997401 (OMIM: 601639,615830) cAMP-dependent pro ( 343) 948 82.7 2.6e-15
NP_002721 (OMIM: 601639,615830) cAMP-dependent pro ( 351) 948 82.7 2.6e-15
NP_001291278 (OMIM: 601639,615830) cAMP-dependent ( 427) 948 82.8 2.9e-15
NP_002723 (OMIM: 176893,616176) cAMP-dependent pro ( 351) 913 80.2 1.4e-14
NP_003943 (OMIM: 608939) ribosomal protein S6 kina ( 482) 817 73.8 1.7e-12
NP_001258972 (OMIM: 608938) ribosomal protein S6 k ( 451) 798 72.4 4.2e-12
NP_001258973 (OMIM: 608938) ribosomal protein S6 k ( 472) 798 72.4 4.3e-12
NP_001258989 (OMIM: 608938) ribosomal protein S6 k ( 502) 798 72.5 4.5e-12
NP_003152 (OMIM: 608938) ribosomal protein S6 kina ( 525) 798 72.5 4.6e-12
XP_016863907 (OMIM: 601591) PREDICTED: cGMP-depend ( 462) 792 72.0 5.7e-12
XP_005274634 (OMIM: 300075,300844,303600) PREDICTE ( 710) 773 71.0 1.8e-11
XP_016885208 (OMIM: 300075,300844,303600) PREDICTE ( 711) 773 71.0 1.8e-11
XP_016885207 (OMIM: 300075,300844,303600) PREDICTE ( 711) 773 71.0 1.8e-11
XP_006724570 (OMIM: 300075,300844,303600) PREDICTE ( 711) 773 71.0 1.8e-11
XP_016885204 (OMIM: 300075,300844,303600) PREDICTE ( 712) 773 71.0 1.8e-11
XP_016885202 (OMIM: 300075,300844,303600) PREDICTE ( 712) 773 71.0 1.8e-11
XP_016885203 (OMIM: 300075,300844,303600) PREDICTE ( 712) 773 71.0 1.8e-11
XP_016885205 (OMIM: 300075,300844,303600) PREDICTE ( 712) 773 71.0 1.8e-11
XP_016885206 (OMIM: 300075,300844,303600) PREDICTE ( 712) 773 71.0 1.8e-11
>>NP_006249 (OMIM: 176894,615436) cGMP-dependent protein (686 aa)
initn: 4552 init1: 4552 opt: 4552 Z-score: 1754.2 bits: 335.0 E(85289): 5.7e-91
Smith-Waterman score: 4552; 100.0% identity (100.0% similar) in 686 aa overlap (1-686:1-686)
10 20 30 40 50 60
pF1KB6 MGTLRDLQYALQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGTLRDLQYALQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QKQSASTLQGEPRTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QKQSASTLQGEPRTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 NLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 KGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 EAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 IRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 ACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 APEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 APEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 NAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTD
610 620 630 640 650 660
670 680
pF1KB6 TSNFDSFPEDNDEPPPDDNSGWDIDF
::::::::::::::::::::::::::
NP_006 TSNFDSFPEDNDEPPPDDNSGWDIDF
670 680
>>NP_001091982 (OMIM: 176894,615436) cGMP-dependent prot (671 aa)
initn: 3989 init1: 3931 opt: 3966 Z-score: 1533.0 bits: 294.0 E(85289): 1.2e-78
Smith-Waterman score: 3997; 91.8% identity (94.9% similar) in 671 aa overlap (18-686:12-671)
10 20 30 40 50 60
pF1KB6 MGTLRDLQYALQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQA
: .. : ::: .:..:.: ::.:. .: : .::. :.
NP_001 MSELEEDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVL-PVP---
10 20 30 40 50
70 80 90 100 110
pF1KB6 QKQSASTLQGEPRTKR-QAISAEPTAF-DIQDLSHVTLPFYPKSPQSKDLIKEAILDNDF
:: : ::: : :.::::: .. ...:: .. : :: .::::::::::::::
NP_001 -----STHIG-PRTTRAQGISAEPQTYRSFHDLRQAFRKF-TKSERSKDLIKEAILDNDF
60 70 80 90 100
120 130 140 150 160 170
pF1KB6 MKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 KVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 SLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRT
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB6 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKA
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB6 KYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQ
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB6 EHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRF
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB6 YTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPE
470 480 490 500 510 520
540 550 560 570 580 590
pF1KB6 YVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKI
530 540 550 560 570 580
600 610 620 630 640 650
pF1KB6 AKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASP
590 600 610 620 630 640
660 670 680
pF1KB6 TDTSNFDSFPEDNDEPPPDDNSGWDIDF
::::::::::::::::::::::::::::
NP_001 TDTSNFDSFPEDNDEPPPDDNSGWDIDF
650 660 670
>>XP_016871901 (OMIM: 176894,615436) PREDICTED: cGMP-dep (591 aa)
initn: 3900 init1: 3900 opt: 3900 Z-score: 1508.5 bits: 289.3 E(85289): 2.7e-77
Smith-Waterman score: 3900; 99.8% identity (100.0% similar) in 584 aa overlap (103-686:8-591)
80 90 100 110 120 130
pF1KB6 RTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVD
:.::::::::::::::::::::::::::::
XP_016 MDRQYCRPRSKDLIKEAILDNDFMKNLELSQIQEIVD
10 20 30
140 150 160 170 180 190
pF1KB6 CMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTR
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB6 TATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVL
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB6 EETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQG
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB6 EDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKL
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB6 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB6 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB6 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDI
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB6 SADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRD
460 470 480 490 500 510
620 630 640 650 660 670
pF1KB6 NPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDND
520 530 540 550 560 570
680
pF1KB6 EPPPDDNSGWDIDF
::::::::::::::
XP_016 EPPPDDNSGWDIDF
580 590
>>XP_016871902 (OMIM: 176894,615436) PREDICTED: cGMP-dep (585 aa)
initn: 3890 init1: 3890 opt: 3890 Z-score: 1504.8 bits: 288.6 E(85289): 4.4e-77
Smith-Waterman score: 3890; 99.8% identity (100.0% similar) in 583 aa overlap (104-686:3-585)
80 90 100 110 120 130
pF1KB6 TKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDC
.:::::::::::::::::::::::::::::
XP_016 MSRSKDLIKEAILDNDFMKNLELSQIQEIVDC
10 20 30
140 150 160 170 180 190
pF1KB6 MYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRT
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB6 ATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLE
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB6 ETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGE
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB6 DVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLS
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB6 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHS
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB6 DFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSK
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB6 GIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDIS
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB6 ADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDN
460 470 480 490 500 510
620 630 640 650 660 670
pF1KB6 PSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDE
520 530 540 550 560 570
680
pF1KB6 PPPDDNSGWDIDF
:::::::::::::
XP_016 PPPDDNSGWDIDF
580
>>XP_011538254 (OMIM: 176894,615436) PREDICTED: cGMP-dep (406 aa)
initn: 2451 init1: 2330 opt: 2330 Z-score: 917.1 bits: 179.4 E(85289): 2.4e-44
Smith-Waterman score: 2330; 99.7% identity (100.0% similar) in 360 aa overlap (1-360:1-360)
10 20 30 40 50 60
pF1KB6 MGTLRDLQYALQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGTLRDLQYALQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QKQSASTLQGEPRTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKQSASTLQGEPRTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 NLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 KGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 KGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 EAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEH
XP_011 IREHNAGICYCCGPQKASNYGRRQRRSRHITWQEQKQERVGEVPDF
370 380 390 400
>>NP_001269414 (OMIM: 601591) cGMP-dependent protein kin (733 aa)
initn: 2225 init1: 1345 opt: 2189 Z-score: 861.6 bits: 170.0 E(85289): 3e-41
Smith-Waterman score: 2189; 49.2% identity (76.4% similar) in 695 aa overlap (4-686:44-733)
10 20 30
pF1KB6 MGTLRDLQYALQEKIEELRQRDALIDELELELD
... .: :.: :.: .. . : :: ::.
NP_001 PDGHSGNLTTDALRNKVTELERELRRKDAEIQEREYHLKELREQLSKQTVAIAELTEELQ
20 30 40 50 60 70
40 50 60 70 80
pF1KB6 QKDELIQKLQNELDKYRSVIRPATQ-----QAQKQSASTLQGEPRTKRQA-ISAEPTA--
.: ..:::. . . :. ........ .. . : .: .:::::.
NP_001 NKCIQLNKLQDVVHMQGGSPLQASPDKVPLEVHRKTSGLVSLHSRRGAKAGVSAEPTTRT
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB6 FDIQDLSHVTLP--FYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDS
.:.. . .. :. . : :: .:. :.:.: :. .::...:.::: .: . :
NP_001 YDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGS
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB6 CIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPG-KVFGELAILYNCTRTATVKTLVNV
:::.:. :. ..:. .:..:: . : :: . : .::::::::::::::.::...::
NP_001 YIIKQGEPGNHIFVLAEGRLEVFQ-GEKLLSSIPMWTTFGELAILYNCTRTASVKAITNV
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB6 KLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEY
: ::.::. ::.:: ::. . .: .::.:: ...:::. :.:. : :: .:..:.:
NP_001 KTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDY
260 270 280 290 300 310
270 280 290 300 310 320
pF1KB6 IIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIA
:::.: .:.::::..:: :.::. ..: ...:: ::..:::::: ..:::.::.::
NP_001 IIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIA
320 330 340 350 360 370
330 340 350 360 370 380
pF1KB6 AEA-VTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTL
: :.::::::..:.. .: ..... : : :. . . : :. ..:.... .:
NP_001 EENDVACLVIDRETFNQTVGTFEELQ-KYLEGYVANLNRDDEKRH-AKRSMSNWKLSKAL
380 390 400 410 420 430
390 400 410 420 430 440
pF1KB6 GVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYR
.. . : :..:.: . .:::: ..:.:::::.::::. :::.:.. : :::.:::
NP_001 SLEMIQLKEKVKVKNE-NVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYR
440 450 460 470 480
450 460 470 480 490 500
pF1KB6 TFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLK
::::.::.:::.:::::::::.::::::::.. :..: .:::.::: ::: ::::::::
NP_001 TFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLK
490 500 510 520 530 540
510 520 530 540 550 560
pF1KB6 PENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGI
::::::: .:: :::::::::::: :.:::::::::::::::.:::::::.:.:.:::::
NP_001 PENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGI
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB6 LMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNL
:.::::::.::::: : : :::.::.::. ..::.::.. .::..:::.::.::::::
NP_001 LVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNL
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB6 KNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSG
:::..::.::.:..:::::::. .: :. . .: : : ::..: .. :: :. ::
NP_001 KNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEKGMPP-DELSG
670 680 690 700 710 720
pF1KB6 WDIDF
:: ::
NP_001 WDKDF
730
>>XP_016863906 (OMIM: 601591) PREDICTED: cGMP-dependent (745 aa)
initn: 2165 init1: 1285 opt: 2087 Z-score: 823.1 bits: 162.8 E(85289): 4.2e-39
Smith-Waterman score: 2087; 49.5% identity (77.1% similar) in 660 aa overlap (4-651:44-699)
10 20 30
pF1KB6 MGTLRDLQYALQEKIEELRQRDALIDELELELD
... .: :.: :.: .. . : :: ::.
XP_016 PDGHSGNLTTDALRNKVTELERELRRKDAEIQEREYHLKELREQLSKQTVAIAELTEELQ
20 30 40 50 60 70
40 50 60 70 80
pF1KB6 QKDELIQKLQNELDKYRSVIRPATQ-----QAQKQSASTLQGEPRTKRQA-ISAEPTA--
.: ..:::. . . :. ........ .. . : .: .:::::.
XP_016 NKCIQLNKLQDVVHMQGGSPLQASPDKVPLEVHRKTSGLVSLHSRRGAKAGVSAEPTTRT
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB6 FDIQDLSHVTLP--FYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDS
.:.. . .. :. . : :: .:. :.:.: :. .::...:.::: .: . :
XP_016 YDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGS
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB6 CIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPG-KVFGELAILYNCTRTATVKTLVNV
:::.:. :. ..:. .:..:: . : :: . : .::::::::::::::.::...::
XP_016 YIIKQGEPGNHIFVLAEGRLEVFQ-GEKLLSSIPMWTTFGELAILYNCTRTASVKAITNV
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB6 KLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEY
: ::.::. ::.:: ::. . .: .::.:: ...:::. :.:. : :: .:..:.:
XP_016 KTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDY
260 270 280 290 300 310
270 280 290 300 310 320
pF1KB6 IIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIA
:::.: .:.::::..:: :.::. ..: ...:: ::..:::::: ..:::.::.::
XP_016 IIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIA
320 330 340 350 360 370
330 340 350 360 370 380
pF1KB6 AEA-VTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTL
: :.::::::..:.. .: ..... : : :. . . : :. ..:.... .:
XP_016 EENDVACLVIDRETFNQTVGTFEELQ-KYLEGYVANLNRDDEKRH-AKRSMSNWKLSKAL
380 390 400 410 420 430
390 400 410 420 430 440
pF1KB6 GVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYR
.. . : :..:.:. .:::: ..:.:::::.::::. :::.:.. : :::.:::
XP_016 SLEMIQLKEKVKVKNENV-AFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYR
440 450 460 470 480
450 460 470 480 490 500
pF1KB6 TFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLK
::::.::.:::.:::::::::.::::::::.. :..: .:::.::: ::: ::::::::
XP_016 TFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLK
490 500 510 520 530 540
510 520 530 540 550 560
pF1KB6 PENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGI
::::::: .:: :::::::::::: :.:::::::::::::::.:::::::.:.:.:::::
XP_016 PENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGI
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB6 LMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNL
:.::::::.::::: : : :::.::.::. ..::.::.. .::..:::.::.::::::
XP_016 LVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNL
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB6 KNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSG
:::..::.::.:..:::::::. .: :.
XP_016 KNGINDIKKHRWLNGFNWEGLKARSLPSPLQREVLYLLYYFFIFFPGICFCTQILDVCMY
670 680 690 700 710 720
>>NP_001269409 (OMIM: 601591) cGMP-dependent protein kin (342 aa)
initn: 1442 init1: 1345 opt: 1492 Z-score: 601.3 bits: 120.7 E(85289): 9.4e-27
Smith-Waterman score: 1492; 64.7% identity (85.6% similar) in 326 aa overlap (361-686:19-342)
340 350 360 370 380 390
pF1KB6 IDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVE
: : : .. .....:: :::::::::::
NP_001 MSNWKLSKALSLEMIQLKEKVARFSSSSPFQNLEIIATLGVGGFGRVE
10 20 30 40
400 410 420 430 440 450
pF1KB6 LVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLY
::..:.: . .:::: ..:.:::::.::::. :::.:.. : :::.:::::::.::.:
NP_001 LVKVKNE-NVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVY
50 60 70 80 90 100
460 470 480 490 500 510
pF1KB6 MLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHR
::.:::::::::.::::::::.. :..: .:::.::: ::: ::::::::::::::: .
NP_001 MLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAE
110 120 130 140 150 160
520 530 540 550 560 570
pF1KB6 GYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGS
:: :::::::::::: :.:::::::::::::::.:::::::.:.:.::::::.::::::.
NP_001 GYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGN
170 180 190 200 210 220
580 590 600 610 620 630
pF1KB6 PPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQK
::::: : : :::.::.::. ..::.::.. .::..:::.::.:::::::::..::.:
NP_001 PPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKK
230 240 250 260 270 280
640 650 660 670 680
pF1KB6 HKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSGWDIDF
:.:..:::::::. .: :. . .: : : ::..: .. :: :. :::: ::
NP_001 HRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEKGMPP-DELSGWDKDF
290 300 310 320 330 340
>>NP_001269410 (OMIM: 601591) cGMP-dependent protein kin (342 aa)
initn: 1442 init1: 1345 opt: 1492 Z-score: 601.3 bits: 120.7 E(85289): 9.4e-27
Smith-Waterman score: 1492; 64.7% identity (85.6% similar) in 326 aa overlap (361-686:19-342)
340 350 360 370 380 390
pF1KB6 IDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVE
: : : .. .....:: :::::::::::
NP_001 MSNWKLSKALSLEMIQLKEKVARFSSSSPFQNLEIIATLGVGGFGRVE
10 20 30 40
400 410 420 430 440 450
pF1KB6 LVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLY
::..:.: . .:::: ..:.:::::.::::. :::.:.. : :::.:::::::.::.:
NP_001 LVKVKNE-NVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVY
50 60 70 80 90 100
460 470 480 490 500 510
pF1KB6 MLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHR
::.:::::::::.::::::::.. :..: .:::.::: ::: ::::::::::::::: .
NP_001 MLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAE
110 120 130 140 150 160
520 530 540 550 560 570
pF1KB6 GYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGS
:: :::::::::::: :.:::::::::::::::.:::::::.:.:.::::::.::::::.
NP_001 GYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGN
170 180 190 200 210 220
580 590 600 610 620 630
pF1KB6 PPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQK
::::: : : :::.::.::. ..::.::.. .::..:::.::.:::::::::..::.:
NP_001 PPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKK
230 240 250 260 270 280
640 650 660 670 680
pF1KB6 HKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSGWDIDF
:.:..:::::::. .: :. . .: : : ::..: .. :: :. :::: ::
NP_001 HRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEKGMPP-DELSGWDKDF
290 300 310 320 330 340
>>XP_005263183 (OMIM: 601591) PREDICTED: cGMP-dependent (762 aa)
initn: 2322 init1: 1345 opt: 1492 Z-score: 598.3 bits: 121.3 E(85289): 1.4e-26
Smith-Waterman score: 2247; 49.6% identity (74.8% similar) in 718 aa overlap (8-686:48-762)
10 20 30
pF1KB6 MGTLRDLQYALQEKIEELRQRDALIDELELELDQKDE
.: :.: :.: .. . : :: ::..:
XP_005 SGNLTTDALRNKVTELERELRRKDAEIQEREYHLKELREQLSKQTVAIAELTEELQNKCI
20 30 40 50 60 70
40 50 60 70 80
pF1KB6 LIQKLQNELDKYRSVIRPATQ-----QAQKQSASTLQGEPRTKRQA-ISAEPTA--FDIQ
..:::. . . :. ........ .. . : .: .:::::. .:..
XP_005 QLNKLQDVVHMQGGSPLQASPDKVPLEVHRKTSGLVSLHSRRGAKAGVSAEPTTRTYDLN
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB6 DLSHVTLP--FYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIK
. .. :. . : :: .:. :.:.: :. .::...:.::: .: . : :::
XP_005 KPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIIK
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB6 EGDVGSLVYVMEDGKVEVTKEGVKLCTMGPG-KVFGELAILYNCTRTATVKTLVNVKLWA
.:. :. ..:. .:..:: . : :: . : .::::::::::::::.::...::: ::
XP_005 QGEPGNHIFVLAEGRLEVFQ-GEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWA
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB6 IDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQ
.::. ::.:: ::. . .: .::.:: ...:::. :.:. : :: .:..:.::::.
XP_005 LDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIRE
260 270 280 290 300 310
270 280 290 300 310 320
pF1KB6 GARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEA-
: .:.::::..:: :.::. ..: ...:: ::..:::::: ..:::.::.:: :
XP_005 GEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEEND
320 330 340 350 360 370
330 340 350 360
pF1KB6 VTCLVIDRDSFKHLIGGLDD--------VSNKAYEDAEAKAKY-----------------
:.::::::..:.. .: ... :.: .: . .::
XP_005 VACLVIDRETFNQTVGTFEELQKYLEGYVANLNRDDEKRHAKRSMSNWKLSKALSLEMIQ
380 390 400 410 420 430
370 380 390 400 410
pF1KB6 --EAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQ
: : : .. .....:: :::::::::::::..:.: . .:::: ..:.:::::.::
XP_005 LKEKVARFSSSSPFQNLEIIATLGVGGFGRVELVKVKNE-NVAFAMKCIRKKHIVDTKQQ
440 450 460 470 480 490
420 430 440 450 460 470
pF1KB6 EHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRF
::. :::.:.. : :::.:::::::.::.:::.:::::::::.::::::::.. :..:
XP_005 EHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKF
500 510 520 530 540 550
480 490 500 510 520 530
pF1KB6 YTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPE
.:::.::: ::: ::::::::::::::: .:: :::::::::::: :.::::::::::
XP_005 CVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPE
560 570 580 590 600 610
540 550 560 570 580 590
pF1KB6 YVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKI
:::::.:::::::.:.:.::::::.::::::.::::: : : :::.::.::. ..::.::
XP_005 YVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKI
620 630 640 650 660 670
600 610 620 630 640 650
pF1KB6 AKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASP
.. .::..:::.::.:::::::::..::.::.:..:::::::. .: :. . .:
XP_005 TRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGP
680 690 700 710 720 730
660 670 680
pF1KB6 TDTSNFDSFPEDNDEPPPDDNSGWDIDF
: : ::..: .. :: :. :::: ::
XP_005 IDHSYFDKYPPEKGMPP-DELSGWDKDF
740 750 760
686 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:31:17 2016 done: Sun Nov 6 15:31:18 2016
Total Scan time: 9.070 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]