Result of FASTA (omim) for
pFN21AB5875
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5875, 465 aa
1>>>pF1KB5875 465 - 465 aa - 465 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8566+/-0.000349; mu= 3.2427+/- 0.022
mean_var=220.4303+/-43.847, 0's: 0 Z-trim(121.1): 33 B-trim: 0 in 0/59
Lambda= 0.086385
statistics sampled from 37308 (37341) to 37308 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.438), width: 16
Scan time: 10.310
The best scores are: opt bits E(85289)
NP_001940 (OMIM: 600427) transcription factor E2F3 ( 465) 3015 388.3 2.4e-107
XP_011512626 (OMIM: 600427) PREDICTED: transcripti ( 459) 2947 379.8 8.3e-105
XP_016865819 (OMIM: 600427) PREDICTED: transcripti ( 379) 2188 285.2 2.1e-76
XP_005248923 (OMIM: 600427) PREDICTED: transcripti ( 335) 2176 283.6 5.5e-76
XP_011512630 (OMIM: 600427) PREDICTED: transcripti ( 338) 2176 283.6 5.5e-76
XP_005248922 (OMIM: 600427) PREDICTED: transcripti ( 340) 2176 283.6 5.5e-76
NP_001230005 (OMIM: 600427) transcription factor E ( 334) 2108 275.2 1.9e-73
NP_004082 (OMIM: 600426) transcription factor E2F2 ( 437) 961 132.3 2.6e-30
XP_011539170 (OMIM: 600426) PREDICTED: transcripti ( 435) 931 128.6 3.4e-29
XP_011539172 (OMIM: 600426) PREDICTED: transcripti ( 350) 928 128.1 3.8e-29
NP_005216 (OMIM: 189971) transcription factor E2F1 ( 437) 797 111.9 3.7e-24
NP_001265204 (OMIM: 602944) transcription factor E ( 249) 612 88.6 2.1e-17
NP_937987 (OMIM: 602944) transcription factor E2F6 ( 281) 612 88.7 2.3e-17
NP_001265206 (OMIM: 602944) transcription factor E ( 206) 558 81.8 1.9e-15
NP_001265207 (OMIM: 602944) transcription factor E ( 206) 558 81.8 1.9e-15
NP_001265205 (OMIM: 602944) transcription factor E ( 206) 558 81.8 1.9e-15
XP_016859037 (OMIM: 602944) PREDICTED: transcripti ( 287) 537 79.3 1.5e-14
XP_016859036 (OMIM: 602944) PREDICTED: transcripti ( 319) 537 79.4 1.6e-14
NP_001941 (OMIM: 600659) transcription factor E2F4 ( 413) 514 76.6 1.4e-13
XP_005245805 (OMIM: 600426) PREDICTED: transcripti ( 249) 492 73.7 6.6e-13
XP_011539173 (OMIM: 600426) PREDICTED: transcripti ( 241) 488 73.2 9.1e-13
XP_005245806 (OMIM: 600426) PREDICTED: transcripti ( 241) 488 73.2 9.1e-13
XP_016859038 (OMIM: 602944) PREDICTED: transcripti ( 244) 483 72.5 1.4e-12
NP_001077057 (OMIM: 600967) transcription factor E ( 345) 484 72.8 1.7e-12
NP_001942 (OMIM: 600967) transcription factor E2F5 ( 346) 481 72.4 2.2e-12
NP_997705 (OMIM: 602944) transcription factor E2F6 ( 129) 306 50.3 3.8e-06
>>NP_001940 (OMIM: 600427) transcription factor E2F3 iso (465 aa)
initn: 3015 init1: 3015 opt: 3015 Z-score: 2048.3 bits: 388.3 E(85289): 2.4e-107
Smith-Waterman score: 3015; 100.0% identity (100.0% similar) in 465 aa overlap (1-465:1-465)
10 20 30 40 50 60
pF1KB5 MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 RGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 WMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 YQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 MKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEG
370 380 390 400 410 420
430 440 450 460
pF1KB5 PFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS
430 440 450 460
>>XP_011512626 (OMIM: 600427) PREDICTED: transcription f (459 aa)
initn: 1913 init1: 1913 opt: 2947 Z-score: 2002.6 bits: 379.8 E(85289): 8.3e-105
Smith-Waterman score: 2947; 98.5% identity (98.7% similar) in 465 aa overlap (1-465:1-459)
10 20 30 40 50 60
pF1KB5 MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 RGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYD
:::::::::::::::::::::::::::::::::::::::::::::::: .:::::
XP_011 RGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPK------KKTRYD
130 140 150 160 170
190 200 210 220 230 240
pF1KB5 TSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 WMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB5 YQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHSP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 MKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEG
360 370 380 390 400 410
430 440 450 460
pF1KB5 PFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS
420 430 440 450
>>XP_016865819 (OMIM: 600427) PREDICTED: transcription f (379 aa)
initn: 2185 init1: 2185 opt: 2188 Z-score: 1492.5 bits: 285.2 E(85289): 2.1e-76
Smith-Waterman score: 2188; 95.8% identity (97.2% similar) in 354 aa overlap (116-465:26-379)
90 100 110 120 130 140
pF1KB5 PSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPP----AKRRLELGES
: .. ..: : .:: ::::::::::
XP_016 MHHKHSSSLSVNQRAVYQTLKNPAAPHTVPESGLRGRLSPPCIPQAKRRLELGES
10 20 30 40 50
150 160 170 180 190 200
pF1KB5 GHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGV
60 70 80 90 100 110
210 220 230 240 250 260
pF1KB5 LDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSK
120 130 140 150 160 170
270 280 290 300 310 320
pF1KB5 EVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAP
180 190 200 210 220 230
330 340 350 360 370 380
pF1KB5 PETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLA
240 250 260 270 280 290
390 400 410 420 430 440
pF1KB5 STNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEE
300 310 320 330 340 350
450 460
pF1KB5 EGISDLFDAYDLEKLPLVEDFMCS
::::::::::::::::::::::::
XP_016 EGISDLFDAYDLEKLPLVEDFMCS
360 370
>>XP_005248923 (OMIM: 600427) PREDICTED: transcription f (335 aa)
initn: 2176 init1: 2176 opt: 2176 Z-score: 1485.2 bits: 283.6 E(85289): 5.5e-76
Smith-Waterman score: 2176; 100.0% identity (100.0% similar) in 334 aa overlap (132-465:2-335)
110 120 130 140 150 160
pF1KB5 TPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAAL
::::::::::::::::::::::::::::::
XP_005 MAKRRLELGESGHQYLSDGLKTPKGKGRAAL
10 20 30
170 180 190 200 210 220
pF1KB5 RSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDI
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB5 TNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCT
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB5 LDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLAS
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB5 TQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLA
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB5 SPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVED
280 290 300 310 320 330
pF1KB5 FMCS
::::
XP_005 FMCS
>>XP_011512630 (OMIM: 600427) PREDICTED: transcription f (338 aa)
initn: 2176 init1: 2176 opt: 2176 Z-score: 1485.1 bits: 283.6 E(85289): 5.5e-76
Smith-Waterman score: 2176; 100.0% identity (100.0% similar) in 334 aa overlap (132-465:5-338)
110 120 130 140 150 160
pF1KB5 TPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAAL
::::::::::::::::::::::::::::::
XP_011 MTLEAKRRLELGESGHQYLSDGLKTPKGKGRAAL
10 20 30
170 180 190 200 210 220
pF1KB5 RSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDI
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB5 TNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCT
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB5 LDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLAS
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB5 TQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLA
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB5 SPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVED
280 290 300 310 320 330
pF1KB5 FMCS
::::
XP_011 FMCS
>>XP_005248922 (OMIM: 600427) PREDICTED: transcription f (340 aa)
initn: 2176 init1: 2176 opt: 2176 Z-score: 1485.1 bits: 283.6 E(85289): 5.5e-76
Smith-Waterman score: 2176; 100.0% identity (100.0% similar) in 334 aa overlap (132-465:7-340)
110 120 130 140 150 160
pF1KB5 TPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAAL
::::::::::::::::::::::::::::::
XP_005 MPLQQQAKRRLELGESGHQYLSDGLKTPKGKGRAAL
10 20 30
170 180 190 200 210 220
pF1KB5 RSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDI
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB5 TNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCT
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB5 LDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLAS
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB5 TQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLA
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB5 SPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVED
280 290 300 310 320 330
pF1KB5 FMCS
::::
XP_005 FMCS
340
>>NP_001230005 (OMIM: 600427) transcription factor E2F3 (334 aa)
initn: 1913 init1: 1913 opt: 2108 Z-score: 1439.4 bits: 275.2 E(85289): 1.9e-73
Smith-Waterman score: 2108; 97.9% identity (98.2% similar) in 334 aa overlap (132-465:7-334)
110 120 130 140 150 160
pF1KB5 TPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAAL
::::::::::::::::::::::::::::::
NP_001 MPLQQQAKRRLELGESGHQYLSDGLKTPKGKGRAAL
10 20 30
170 180 190 200 210 220
pF1KB5 RSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDI
::::::: .::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSPDSPK------KKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDI
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB5 TNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCT
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB5 LDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLAS
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB5 TQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLA
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB5 SPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVED
280 290 300 310 320 330
pF1KB5 FMCS
::::
NP_001 FMCS
>>NP_004082 (OMIM: 600426) transcription factor E2F2 [Ho (437 aa)
initn: 994 init1: 746 opt: 961 Z-score: 665.3 bits: 132.3 E(85289): 2.6e-30
Smith-Waterman score: 1084; 48.8% identity (67.3% similar) in 449 aa overlap (38-456:1-434)
10 20 30 40 50 60
pF1KB5 ALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTST
.: .: : :.::. .: . . :.
NP_004 MLQGPR-ALASAAGQTPKVVPAMSPTELWP
10 20
70 80 90 100 110 120
pF1KB5 TSCSSSLQSGAVAA--GPLLP-SAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGS
.. :: :.:. :: : .:: : . :. : .::::: .. ... ::
NP_004 SGLSSPQLCPATATYYTPLYPQTAPPAA-APGTCLDATPHGPEGQ--VVRCLPA------
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB5 GGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLG
: ::::.:.: :. . . . ::::: . : ::::::::.::::::::::
NP_004 ---GRLPAKRKLDLEGIGRPVVPE-FPTPKGKCIRVDGLP-SPKTPKSPGEKTRYDTSLG
90 100 110 120 130
190 200 210 220 230 240
pF1KB5 LLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGC
::::::: :::.: ::::::: ::::: ::::::::::::::::.::.::.:::.::.:
NP_004 LLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKAKNNIQWVGR
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB5 SLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDI
.. :: .. : :..:. :: . :. ::.:::::.:..: ::::. :.::::::::::
NP_004 GMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTEDKANKRLAYVTYQDI
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB5 RKISGLKDQTVIVVKAPPETRLEVPDSIE-SLQIHLASTQGPIEVYLCPEET-ETHSPMK
: ....:.::::.:::::.::::::: : .:::.: ::::::::::::::. : :: .
NP_004 RAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSE
260 270 280 290 300 310
370 380 390 400
pF1KB5 TNNQDHNGNIPKPAS-KDLASTNSGHSDCSVSM--------------GNLSPLAS-----
. . :.: : . .::. . . ..: .: :: .
NP_004 EPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAPPPPSLVPLEATDSLL
320 330 340 350 360 370
410 420 430 440 450
pF1KB5 --PANLLQQTEDQI--PS-NLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLP
: ::::::::. :. .:.... : : :.::: .: ::::::::.::: :
NP_004 ELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGEGISDLFDSYDLGDLL
380 390 400 410 420 430
460
pF1KB5 LVEDFMCS
NP_004 IN
>>XP_011539170 (OMIM: 600426) PREDICTED: transcription f (435 aa)
initn: 656 init1: 408 opt: 931 Z-score: 645.1 bits: 128.6 E(85289): 3.4e-29
Smith-Waterman score: 1054; 48.6% identity (66.8% similar) in 449 aa overlap (38-456:1-432)
10 20 30 40 50 60
pF1KB5 ALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTST
.: .: : :.::. .: . . :.
XP_011 MLQGPR-ALASAAGQTPKVVPAMSPTELWP
10 20
70 80 90 100 110 120
pF1KB5 TSCSSSLQSGAVAA--GPLLP-SAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGS
.. :: :.:. :: : .:: : . :. : .::::: .. ... ::
XP_011 SGLSSPQLCPATATYYTPLYPQTAPPAA-APGTCLDATPHGPEGQ--VVRCLPA------
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB5 GGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLG
: ::::.:.: :. . . . ::::: . : ::::::::.::::::::::
XP_011 ---GRLPAKRKLDLEGIGRPVVPE-FPTPKGKCIRVDGLP-SPKTPKSPGEKTRYDTSLG
90 100 110 120 130
190 200 210 220 230 240
pF1KB5 LLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGC
::::::: :::.: ::::::: ::::: ::::::::::::::::.::.::.:::.: :
XP_011 LLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKAKNNIQ--GR
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB5 SLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDI
.. :: .. : :..:. :: . :. ::.:::::.:..: ::::. :.::::::::::
XP_011 GMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTEDKANKRLAYVTYQDI
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB5 RKISGLKDQTVIVVKAPPETRLEVPDSIE-SLQIHLASTQGPIEVYLCPEET-ETHSPMK
: ....:.::::.:::::.::::::: : .:::.: ::::::::::::::. : :: .
XP_011 RAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSE
260 270 280 290 300 310
370 380 390 400
pF1KB5 TNNQDHNGNIPKPAS-KDLASTNSGHSDCSVSM--------------GNLSPLAS-----
. . :.: : . .::. . . ..: .: :: .
XP_011 EPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAPPPPSLVPLEATDSLL
320 330 340 350 360 370
410 420 430 440 450
pF1KB5 --PANLLQQTEDQI--PS-NLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLP
: ::::::::. :. .:.... : : :.::: .: ::::::::.::: :
XP_011 ELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGEGISDLFDSYDLGDLL
380 390 400 410 420 430
460
pF1KB5 LVEDFMCS
XP_011 IN
>>XP_011539172 (OMIM: 600426) PREDICTED: transcription f (350 aa)
initn: 936 init1: 746 opt: 928 Z-score: 644.4 bits: 128.1 E(85289): 3.8e-29
Smith-Waterman score: 981; 51.1% identity (70.6% similar) in 374 aa overlap (38-405:1-350)
10 20 30 40 50 60
pF1KB5 ALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTST
.: .: : :.::. .: . . :.
XP_011 MLQGPR-ALASAAGQTPKVVPAMSPTELWP
10 20
70 80 90 100 110 120
pF1KB5 TSCSSSLQSGAVAA--GPLLP-SAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGS
.. :: :.:. :: : .:: : . :. : .::::: .. ... :: ::
XP_011 SGLSSPQLCPATATYYTPLYPQTAPPAA-APGTCLDATPHGPEGQ--VVRCLPA-GR---
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB5 GGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLG
::::.:.: :. . . . ::::: . : ::::::::.::::::::::
XP_011 -----LPAKRKLDLEGIGRPVVPE-FPTPKGKCIRVDGLP-SPKTPKSPGEKTRYDTSLG
90 100 110 120 130
190 200 210 220 230 240
pF1KB5 LLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGC
::::::: :::.: ::::::: ::::: ::::::::::::::::.::.::.:::.::.:
XP_011 LLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKAKNNIQWVGR
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB5 SLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDI
.. :: .. : :..:. :: . :. ::.:::::.:..: ::::. :.::::::::::
XP_011 GMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTEDKANKRLAYVTYQDI
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB5 RKISGLKDQTVIVVKAPPETRLEVPDSIE-SLQIHLASTQGPIEVYLCPEET-ETHSPMK
: ....:.::::.:::::.::::::: : .:::.: ::::::::::::::. : :: .
XP_011 RAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSE
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB5 TNNQDHNGNIPKPASKDLA-STNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEGP
: :... : : .:.. . :.. . . : :: :.
XP_011 E---------PLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSAS
320 330 340 350
430 440 450 460
pF1KB5 FVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS
465 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:12:07 2016 done: Mon Nov 7 17:12:09 2016
Total Scan time: 10.310 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]