Result of FASTA (omim) for
pFN21AB5794
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5794, 780 aa
1>>>pF1KB5794 780 - 780 aa - 780 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9613+/-0.000441; mu= 14.1821+/- 0.028
mean_var=180.2224+/-36.653, 0's: 0 Z-trim(116.3): 135 B-trim: 495 in 2/48
Lambda= 0.095537
statistics sampled from 27291 (27439) to 27291 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.322), width: 16
Scan time: 11.130
The best scores are: opt bits E(85289)
NP_003153 (OMIM: 614765) striatin [Homo sapiens] ( 780) 5149 723.0 1.2e-207
NP_001077362 (OMIM: 614766) striatin-3 isoform 1 [ ( 797) 3333 472.7 2.6e-132
XP_011531375 (OMIM: 614765) PREDICTED: striatin is ( 809) 2866 408.4 6.3e-113
XP_005264576 (OMIM: 614765) PREDICTED: striatin is ( 743) 2865 408.2 6.5e-113
XP_005267626 (OMIM: 614766) PREDICTED: striatin-3 ( 760) 2047 295.5 5.8e-79
NP_055389 (OMIM: 614766) striatin-3 isoform 2 [Hom ( 713) 1907 276.1 3.5e-73
XP_005267627 (OMIM: 614766) PREDICTED: striatin-3 ( 750) 1900 275.2 7.2e-73
XP_006723237 (OMIM: 614767) PREDICTED: striatin-4 ( 641) 1529 224.0 1.6e-57
XP_016882206 (OMIM: 614767) PREDICTED: striatin-4 ( 641) 1529 224.0 1.6e-57
XP_016882205 (OMIM: 614767) PREDICTED: striatin-4 ( 656) 1529 224.0 1.6e-57
NP_001034966 (OMIM: 614767) striatin-4 isoform 2 [ ( 760) 1529 224.1 1.8e-57
XP_006723234 (OMIM: 614767) PREDICTED: striatin-4 ( 775) 1529 224.1 1.8e-57
XP_016882207 (OMIM: 614767) PREDICTED: striatin-4 ( 539) 1519 222.5 3.7e-57
XP_011525181 (OMIM: 614767) PREDICTED: striatin-4 ( 365) 1510 221.1 6.7e-57
NP_037535 (OMIM: 614767) striatin-4 isoform 1 [Hom ( 753) 1515 222.1 6.8e-57
XP_006723235 (OMIM: 614767) PREDICTED: striatin-4 ( 768) 1515 222.1 6.9e-57
XP_016882208 (OMIM: 614767) PREDICTED: striatin-4 ( 466) 769 119.1 4.4e-26
XP_011525180 (OMIM: 614767) PREDICTED: striatin-4 ( 481) 669 105.3 6.3e-22
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 219 43.1 0.0024
NP_002066 (OMIM: 139130,145500,617024) guanine nuc ( 340) 218 43.0 0.0026
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 219 43.2 0.0027
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 219 43.2 0.0027
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 219 43.2 0.0027
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 219 43.2 0.0027
XP_011519255 (OMIM: 139130,145500,617024) PREDICTE ( 360) 218 43.0 0.0027
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 219 43.2 0.0028
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 219 43.2 0.0028
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 219 43.2 0.0028
NP_005264 (OMIM: 139390) guanine nucleotide-bindin ( 340) 214 42.4 0.0038
XP_016856548 (OMIM: 139380,613065,616973) PREDICTE ( 340) 212 42.2 0.0046
XP_016856550 (OMIM: 139380,613065,616973) PREDICTE ( 340) 212 42.2 0.0046
NP_002065 (OMIM: 139380,613065,616973) guanine nuc ( 340) 212 42.2 0.0046
XP_016856549 (OMIM: 139380,613065,616973) PREDICTE ( 340) 212 42.2 0.0046
NP_001269468 (OMIM: 139380,613065,616973) guanine ( 340) 212 42.2 0.0046
>>NP_003153 (OMIM: 614765) striatin [Homo sapiens] (780 aa)
initn: 5149 init1: 5149 opt: 5149 Z-score: 3849.2 bits: 723.0 E(85289): 1.2e-207
Smith-Waterman score: 5149; 100.0% identity (100.0% similar) in 780 aa overlap (1-780:1-780)
10 20 30 40 50 60
pF1KB5 MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KRVRALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KRVRALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTKEALKEFDFLVTSEEGDNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTKEALKEFDFLVTSEEGDNE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLAN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEALESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEALESE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 LGLGELAGLTVANEADSLTYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LGLGELAGLTVANEADSLTYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLIT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 ASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 QGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 VAPALSVFNDTKELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VAPALSVFNDTKELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDTT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 ANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 LMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVFV
730 740 750 760 770 780
>>NP_001077362 (OMIM: 614766) striatin-3 isoform 1 [Homo (797 aa)
initn: 2616 init1: 2012 opt: 3333 Z-score: 2496.4 bits: 472.7 E(85289): 2.6e-132
Smith-Waterman score: 3333; 64.2% identity (84.0% similar) in 787 aa overlap (3-780:20-797)
10 20 30 40
pF1KB5 MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAA
.: ::: .. . : :.: : :: : . .:: .:. .
NP_001 MDELAGGGGGGPGMAAPPRQQQGPGGNLGLSPGGNGAAGGGGPPA-SEGAGPAAGPELSR
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 RAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIK
::..:::::..::::::::.:::.::::::::::.:::::::::::::::::::::::
NP_001 PQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 MLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQ-QNSQLMWKQGRQLL
::::::::::::::::::::::::::.: :...:.: ..::. ::::: ::::::::
NP_001 MLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEAPTAPQNSQLTWKQGRQLL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 RQYLQEVGYTDTILDVKSKRVRALLGFS-SDVTDREDDKNQDSVVNGTEAEVKETAMIAK
::::::::::::::::.:.:::.:::.: :. . . :: ....:: :. .. : .
NP_001 RQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPKQKGQEIKR
180 190 200 210 220 230
230 240 250 260 270
pF1KB5 SELTDSASVLDNFKFLESAAADFSDEDEDDDV-----DGREKSVIDTSTIVRKKALPDSG
: :..::..:.:::. :: :::::..:. .:..: .. : . :
NP_001 S----SGDVLETFNFLEN--ADDSDEDEENDMIEGIPEGKDKHRMNKHKIGNEGLAADLT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 EDRDTKEALKEFDFLVTSEEGDN--ESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKE
.: ::.:::::::::::.:.:.. :.::.::::.:.:.: :.:.::::.:.::::
NP_001 DDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWDKDDLSPTAEVWDVDQGLISKLKE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 QYKKERKGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRAD
:::::::::::::: ::.:: ::.:.: : :::: . .. . :: .:.:. .:: ::.
NP_001 QYKKERKGKKGVKRANRTKLYDMIADLGD-DELPHIPSGIINQSRSASTRMTDHEGARAE
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB5 EVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALRKTWN
:.: .::: ..:::::::.:..: : ::::.:: :::.:.:: .::. ::::.:::::
NP_001 EAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDAD-YSYDLPANKDAFRKTWN
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB5 PKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRA
::.::::::::.:::::::.::::.:::::::::.::::::.:::::.::::::::::::
NP_001 PKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRA
480 490 500 510 520 530
520 530 540 550 560 570
pF1KB5 HKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWG
: :::: ...:::::::.::: :. :: :: .:..::::.:.:.:: : :.::::::::
NP_001 HIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPSVDPYDTYEPNVLAGTLVGHTDAVWG
540 550 560 570 580 590
580 590 600 610 620 630
pF1KB5 LAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDTKELGIPASVDLVSSDPSHMVASF
::::. ...:::::::::.:::: : : . ..: :. :::.:::... ::.:::.::
NP_001 LAYSGIKNQLLSCSADGTVRLWNPQEKLPCICTYNGDKKHGIPTSVDFIGCDPAHMVTSF
600 610 620 630 640 650
640 650 660 670 680 690
pF1KB5 SKGYTSIFNMETQQRILTLESNVDTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNN
. : . :...::.: .. : :.::. .:. .::::.::::::..:::::::::::.::.
NP_001 NTGSAVIYDLETSQSLVILSSQVDSGLQSNNHINRVVSHPTLPVTITAHEDRHIKFFDNK
660 670 680 690 700 710
700 710 720 730 740 750
pF1KB5 TGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEES
:::.::::::::.:::::::::::.::::::::::::::::.::::.::.::::::..::
NP_001 TGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDES
720 730 740 750 760 770
760 770 780
pF1KB5 IHDVAFHPSKCYIASAGADALAKVFV
:.::::: :: :::::::::::::::
NP_001 IYDVAFHSSKAYIASAGADALAKVFV
780 790
>>XP_011531375 (OMIM: 614765) PREDICTED: striatin isofor (809 aa)
initn: 2865 init1: 2865 opt: 2866 Z-score: 2148.4 bits: 408.4 E(85289): 6.3e-113
Smith-Waterman score: 5081; 96.4% identity (96.4% similar) in 809 aa overlap (1-780:1-809)
10 20 30 40 50 60
pF1KB5 MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KRVRALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRVRALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTKEALKEFDFLVTSEEGDNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTKEALKEFDFLVTSEEGDNE
250 260 270 280 290 300
310 320 330 340
pF1KB5 SRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKR------------
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRKTTEDLFQPLSY
310 320 330 340 350 360
350 360 370 380 390
pF1KB5 -----------------PNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEIN
:::::::::::::::::::::::::::::::::::::::::::
XP_011 IKQSKQGCGRMKNQSLGPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEIN
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 RADEVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RADEVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALRK
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB5 TWNPKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWNPKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYT
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB5 FRAHKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNIDPYDSYDPSVLRGPLLGHTDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRAHKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNIDPYDSYDPSVLRGPLLGHTDA
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB5 VWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDTKELGIPASVDLVSSDPSHMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDTKELGIPASVDLVSSDPSHMV
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB5 ASFSKGYTSIFNMETQQRILTLESNVDTTANSSCQINRVISHPTLPISITAHEDRHIKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASFSKGYTSIFNMETQQRILTLESNVDTTANSSCQINRVISHPTLPISITAHEDRHIKFY
670 680 690 700 710 720
700 710 720 730 740 750
pF1KB5 DNNTGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNNTGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKF
730 740 750 760 770 780
760 770 780
pF1KB5 EESIHDVAFHPSKCYIASAGADALAKVFV
:::::::::::::::::::::::::::::
XP_011 EESIHDVAFHPSKCYIASAGADALAKVFV
790 800
>>XP_005264576 (OMIM: 614765) PREDICTED: striatin isofor (743 aa)
initn: 4876 init1: 2865 opt: 2865 Z-score: 2148.1 bits: 408.2 E(85289): 6.5e-113
Smith-Waterman score: 4804; 95.3% identity (95.3% similar) in 780 aa overlap (1-780:1-743)
10 20 30 40 50 60
pF1KB5 MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KRVRALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRVRALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTKEALKEFDFLVTSEEGDNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTKEALKEFDFLVTSEEGDNE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLAN
:::::::::: : ::::::::::::
XP_005 SRSAGDGTDW-------------------------------G------PNRSKLQDMLAN
310 320
370 380 390 400 410 420
pF1KB5 LRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEALESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEALESE
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB5 LGLGELAGLTVANEADSLTYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGLGELAGLTVANEADSLTYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLIT
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB5 ASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLI
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB5 QGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTE
510 520 530 540 550 560
610 620 630 640 650 660
pF1KB5 VAPALSVFNDTKELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAPALSVFNDTKELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDTT
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB5 ANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLY
630 640 650 660 670 680
730 740 750 760 770 780
pF1KB5 LMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVFV
690 700 710 720 730 740
>>XP_005267626 (OMIM: 614766) PREDICTED: striatin-3 isof (760 aa)
initn: 2917 init1: 1745 opt: 2047 Z-score: 1538.7 bits: 295.5 E(85289): 5.8e-79
Smith-Waterman score: 3065; 60.9% identity (80.1% similar) in 787 aa overlap (3-780:20-760)
10 20 30 40
pF1KB5 MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAA
.: ::: .. . : :.: : :: : . .:: .:. .
XP_005 MDELAGGGGGGPGMAAPPRQQQGPGGNLGLSPGGNGAAGGGGPPA-SEGAGPAAGPELSR
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 RAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIK
::..:::::..::::::::.:::.::::::::::.:::::::::::::::::::::::
XP_005 PQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 MLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQ-QNSQLMWKQGRQLL
::::::::::::::::::::::::::.: :...:.: ..::. ::::: ::::::::
XP_005 MLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEAPTAPQNSQLTWKQGRQLL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 RQYLQEVGYTDTILDVKSKRVRALLGFS-SDVTDREDDKNQDSVVNGTEAEVKETAMIAK
::::::::::::::::.:.:::.:::.: :. . . :: ....:: :. .. : .
XP_005 RQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPKQKGQEIKR
180 190 200 210 220 230
230 240 250 260 270
pF1KB5 SELTDSASVLDNFKFLESAAADFSDEDEDDDV-----DGREKSVIDTSTIVRKKALPDSG
: :..::..:.:::. :: :::::..:. .:..: .. : . :
XP_005 S----SGDVLETFNFLEN--ADDSDEDEENDMIEGIPEGKDKHRMNKHKIGNEGLAADLT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 EDRDTKEALKEFDFLVTSEEGDN--ESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKE
.: ::.:::::::::::.:.:.. :.::.::::.: :.
XP_005 DDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEW----------------GA------
300 310 320 330
340 350 360 370 380 390
pF1KB5 QYKKERKGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRAD
::.:: ::.:.: : :::: . .. . :: .:.:. .:: ::.
XP_005 ---------------NRTKLYDMIADLGD-DELPHIPSGIINQSRSASTRMTDHEGARAE
340 350 360 370
400 410 420 430 440 450
pF1KB5 EVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALRKTWN
:.: .::: ..:::::::.:..: : ::::.:: :::.:.:: .::. ::::.:::::
XP_005 EAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDAD-YSYDLPANKDAFRKTWN
380 390 400 410 420 430
460 470 480 490 500 510
pF1KB5 PKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRA
::.::::::::.:::::::.::::.:::::::::.::::::.:::::.::::::::::::
XP_005 PKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRA
440 450 460 470 480 490
520 530 540 550 560 570
pF1KB5 HKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWG
: :::: ...:::::::.::: :. :: :: .:..::::.:.:.:: : :.::::::::
XP_005 HIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPSVDPYDTYEPNVLAGTLVGHTDAVWG
500 510 520 530 540 550
580 590 600 610 620 630
pF1KB5 LAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDTKELGIPASVDLVSSDPSHMVASF
::::. ...:::::::::.:::: : : . ..: :. :::.:::... ::.:::.::
XP_005 LAYSGIKNQLLSCSADGTVRLWNPQEKLPCICTYNGDKKHGIPTSVDFIGCDPAHMVTSF
560 570 580 590 600 610
640 650 660 670 680 690
pF1KB5 SKGYTSIFNMETQQRILTLESNVDTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNN
. : . :...::.: .. : :.::. .:. .::::.::::::..:::::::::::.::.
XP_005 NTGSAVIYDLETSQSLVILSSQVDSGLQSNNHINRVVSHPTLPVTITAHEDRHIKFFDNK
620 630 640 650 660 670
700 710 720 730 740 750
pF1KB5 TGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEES
:::.::::::::.:::::::::::.::::::::::::::::.::::.::.::::::..::
XP_005 TGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDES
680 690 700 710 720 730
760 770 780
pF1KB5 IHDVAFHPSKCYIASAGADALAKVFV
:.::::: :: :::::::::::::::
XP_005 IYDVAFHSSKAYIASAGADALAKVFV
740 750 760
>>NP_055389 (OMIM: 614766) striatin-3 isoform 2 [Homo sa (713 aa)
initn: 2681 init1: 1745 opt: 1907 Z-score: 1434.7 bits: 276.1 E(85289): 3.5e-73
Smith-Waterman score: 2834; 57.9% identity (75.5% similar) in 787 aa overlap (3-780:20-713)
10 20 30 40
pF1KB5 MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAA
.: ::: .. . : :.: : :: : . .:: .:. .
NP_055 MDELAGGGGGGPGMAAPPRQQQGPGGNLGLSPGGNGAAGGGGPPA-SEGAGPAAGPELSR
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 RAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIK
::..:::::..::::::::.:::.::::::::::.:::::::::::::::::::::::
NP_055 PQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 MLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQ-QNSQLMWKQGRQLL
::::::::::::::::::::::::::.: :...:.: ..::. ::::: ::::::::
NP_055 MLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEAPTAPQNSQLTWKQGRQLL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 RQYLQEVGYTDTILDVKSKRVRALLGFS-SDVTDREDDKNQDSVVNGTEAEVKETAMIAK
::::::::::::::::.:.:::.:::.: :. . . :: ....:: :. .. : .
NP_055 RQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPKQKGQEIKR
180 190 200 210 220 230
230 240 250 260 270
pF1KB5 SELTDSASVLDNFKFLESAAADFSDEDEDDDV-----DGREKSVIDTSTIVRKKALPDSG
: :..::..:.:::. :: :::::..:. .:..: .. : . :
NP_055 S----SGDVLETFNFLEN--ADDSDEDEENDMIEGIPEGKDKHRMNKHKIGNEGLAADLT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 EDRDTKEALKEFDFLVTSEEGDN--ESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKE
.: ::.:::::::::::.:.:.. :.::.::::.:
NP_055 DDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEW------------------------
300 310 320
340 350 360 370 380 390
pF1KB5 QYKKERKGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRAD
NP_055 ------------------------------------------------------------
400 410 420 430 440 450
pF1KB5 EVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALRKTWN
.: .::: ..:::::::.:..: : ::::.:: :::.:.:: .::. ::::.:::::
NP_055 -AEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDAD-YSYDLPANKDAFRKTWN
330 340 350 360 370 380
460 470 480 490 500 510
pF1KB5 PKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRA
::.::::::::.:::::::.::::.:::::::::.::::::.:::::.::::::::::::
NP_055 PKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRA
390 400 410 420 430 440
520 530 540 550 560 570
pF1KB5 HKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWG
: :::: ...:::::::.::: :. :: :: .:..::::.:.:.:: : :.::::::::
NP_055 HIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPSVDPYDTYEPNVLAGTLVGHTDAVWG
450 460 470 480 490 500
580 590 600 610 620 630
pF1KB5 LAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDTKELGIPASVDLVSSDPSHMVASF
::::. ...:::::::::.:::: : : . ..: :. :::.:::... ::.:::.::
NP_055 LAYSGIKNQLLSCSADGTVRLWNPQEKLPCICTYNGDKKHGIPTSVDFIGCDPAHMVTSF
510 520 530 540 550 560
640 650 660 670 680 690
pF1KB5 SKGYTSIFNMETQQRILTLESNVDTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNN
. : . :...::.: .. : :.::. .:. .::::.::::::..:::::::::::.::.
NP_055 NTGSAVIYDLETSQSLVILSSQVDSGLQSNNHINRVVSHPTLPVTITAHEDRHIKFFDNK
570 580 590 600 610 620
700 710 720 730 740 750
pF1KB5 TGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEES
:::.::::::::.:::::::::::.::::::::::::::::.::::.::.::::::..::
NP_055 TGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDES
630 640 650 660 670 680
760 770 780
pF1KB5 IHDVAFHPSKCYIASAGADALAKVFV
:.::::: :: :::::::::::::::
NP_055 IYDVAFHSSKAYIASAGADALAKVFV
690 700 710
>>XP_005267627 (OMIM: 614766) PREDICTED: striatin-3 isof (750 aa)
initn: 2840 init1: 1745 opt: 1900 Z-score: 1429.3 bits: 275.2 E(85289): 7.2e-73
Smith-Waterman score: 3084; 61.2% identity (79.5% similar) in 787 aa overlap (3-780:20-750)
10 20 30 40
pF1KB5 MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAA
.: ::: .. . : :.: : :: : . .:: .:. .
XP_005 MDELAGGGGGGPGMAAPPRQQQGPGGNLGLSPGGNGAAGGGGPPA-SEGAGPAAGPELSR
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 RAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIK
::..:::::..::::::::.:::.::::::::::.:::::::::::::::::::::::
XP_005 PQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 MLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQ-QNSQLMWKQGRQLL
::::::::::::::::::::::::::.: :...:.: ..::. ::::: ::::::::
XP_005 MLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEAPTAPQNSQLTWKQGRQLL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 RQYLQEVGYTDTILDVKSKRVRALLGFS-SDVTDREDDKNQDSVVNGTEAEVKETAMIAK
::::::::::::::::.:.:::.:::.: :. . . :: ....:: :. .. : .
XP_005 RQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPKQKGQEIKR
180 190 200 210 220 230
230 240 250 260 270
pF1KB5 SELTDSASVLDNFKFLESAAADFSDEDEDDDV-----DGREKSVIDTSTIVRKKALPDSG
: :..::..:.:::. :: :::::..:. .:..: .. : . :
XP_005 S----SGDVLETFNFLEN--ADDSDEDEENDMIEGIPEGKDKHRMNKHKIGNEGLAADLT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 EDRDTKEALKEFDFLVTSEEGDN--ESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKE
.: ::.:::::::::::.:.:.. :.::.::::.:.:.: :.:.::::.:.::::
XP_005 DDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWDKDDLSPTAEVWDVDQGLISKLKE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 QYKKERKGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRAD
:::::::::::::
XP_005 QYKKERKGKKGVK-----------------------------------------------
360
400 410 420 430 440 450
pF1KB5 EVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALRKTWN
.: .::: ..:::::::.:..: : ::::.:: :::.:.:: .::. ::::.:::::
XP_005 -TEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDAD-YSYDLPANKDAFRKTWN
370 380 390 400 410 420
460 470 480 490 500 510
pF1KB5 PKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRA
::.::::::::.:::::::.::::.:::::::::.::::::.:::::.::::::::::::
XP_005 PKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRA
430 440 450 460 470 480
520 530 540 550 560 570
pF1KB5 HKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWG
: :::: ...:::::::.::: :. :: :: .:..::::.:.:.:: : :.::::::::
XP_005 HIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPSVDPYDTYEPNVLAGTLVGHTDAVWG
490 500 510 520 530 540
580 590 600 610 620 630
pF1KB5 LAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDTKELGIPASVDLVSSDPSHMVASF
::::. ...:::::::::.:::: : : . ..: :. :::.:::... ::.:::.::
XP_005 LAYSGIKNQLLSCSADGTVRLWNPQEKLPCICTYNGDKKHGIPTSVDFIGCDPAHMVTSF
550 560 570 580 590 600
640 650 660 670 680 690
pF1KB5 SKGYTSIFNMETQQRILTLESNVDTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNN
. : . :...::.: .. : :.::. .:. .::::.::::::..:::::::::::.::.
XP_005 NTGSAVIYDLETSQSLVILSSQVDSGLQSNNHINRVVSHPTLPVTITAHEDRHIKFFDNK
610 620 630 640 650 660
700 710 720 730 740 750
pF1KB5 TGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEES
:::.::::::::.:::::::::::.::::::::::::::::.::::.::.::::::..::
XP_005 TGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDES
670 680 690 700 710 720
760 770 780
pF1KB5 IHDVAFHPSKCYIASAGADALAKVFV
:.::::: :: :::::::::::::::
XP_005 IYDVAFHSSKAYIASAGADALAKVFV
730 740 750
>>XP_006723237 (OMIM: 614767) PREDICTED: striatin-4 isof (641 aa)
initn: 2036 init1: 750 opt: 1529 Z-score: 1153.7 bits: 224.0 E(85289): 1.6e-57
Smith-Waterman score: 1972; 49.1% identity (71.4% similar) in 693 aa overlap (104-780:1-641)
80 90 100 110 120 130
pF1KB5 RAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDMKPP
:::::::::::::::::.::.::::. :
XP_006 MLEYALKQERAKYHKLKFGTDLNQGEKKAD
10 20 30
140 150 160 170 180 190
pF1KB5 SYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSDV
.. .. .: .:: :.::.:::::::::.::::::::::..:::::.::: : ..
XP_006 VSEQVSNGPVESVTLENSPLVWKEGRQLLRQYLEEVGYTDTILDMRSKRVRSLLGRSLEL
40 50 60 70 80 90
200 210 220 230
pF1KB5 TDREDDKN---------------QDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLE
. . .. .. .:. : ..:..: .. ..::: .. ::.
XP_006 NGAVEPSEGAPRAPPGPAGLSGGESLLVKQIEEQIKRNAAGKDGKERLGGSVLGQIPFLQ
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB5 SAAADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTKEALKEFDFLVTSEEGD
. . ::::.. : ..:. . . . . : :. :...:..::::: ..:.:.
XP_006 NCEDEDSDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSEDAINEFDFLGSGEDGE
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB5 NESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDML
.: : :. .:: : .:. . : ::: .:
XP_006 ----GAPD------------PRRCTVD-GSPHELESR---------------RVKLQGIL
220 230
360 370 380 390 400 410
pF1KB5 ANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEALE
:.::::: :: :.: .: :.. . :: .: :: ::: :
XP_006 ADLRDVDGLP---PKVTGPP-PGTPQPRPHE---------GSFGFSSD-VFIM--DTIGG
240 250 260 270 280
420 430 440 450 460 470
pF1KB5 SELGLGELAGLTVANEADSLTYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVL
.:..::.:: :::.:. : :. :....:::..::::::::::::.::::.:::: . .:
XP_006 GEVSLGDLADLTVTNDND-LSCDLSDSKDAFKKTWNPKFTLRSHYDGIRSLAFHHSQSAL
290 300 310 320 330 340
480 490 500 510 520 530
pF1KB5 ITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDG
.::::: :::.:::::.. :::...::::::..::::.:::: :.:.::.: :::::.:.
XP_006 LTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVAMGSNSEYCYSGGADA
350 360 370 380 390 400
540 550 560 570 580 590
pF1KB5 LIQGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNT
:..:. . ..::::.:::::: : :: :::::::.: . ::: :::::::.:.:.
XP_006 CIHSWKIPDLSMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDP
410 420 430 440 450 460
600 610 620 630 640 650
pF1KB5 TEVAPA-LSVFNDTKELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNV
. .:: : .: ..: :.:.:: ..:..:.:.:::: .: : ...::. . .:::::
XP_006 SSSSPACLCTFPTASEHGVPTSVAFTSTEPAHIVASFRSGDTVLYDMEVGSALLTLESR-
470 480 490 500 510 520
660 670 680 690 700 710
pF1KB5 DTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPN
... :::.:.:::. :..::::.:: :.: :: ::: .:::::::.::: ::::::
XP_006 --GSSGPTQINQVVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSMVAHLDAVTCLAVDPN
530 540 550 560 570
720 730 740 750 760 770
pF1KB5 GLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAK
: .:::::::::.:::.:..:::.::.:::::: ::.:: :: :::: :::::::::::
XP_006 GAFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACHPSKALIASAGADALAK
580 590 600 610 620 630
780
pF1KB5 VFV
:::
XP_006 VFV
640
>>XP_016882206 (OMIM: 614767) PREDICTED: striatin-4 isof (641 aa)
initn: 2036 init1: 750 opt: 1529 Z-score: 1153.7 bits: 224.0 E(85289): 1.6e-57
Smith-Waterman score: 1972; 49.1% identity (71.4% similar) in 693 aa overlap (104-780:1-641)
80 90 100 110 120 130
pF1KB5 RAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDMKPP
:::::::::::::::::.::.::::. :
XP_016 MLEYALKQERAKYHKLKFGTDLNQGEKKAD
10 20 30
140 150 160 170 180 190
pF1KB5 SYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSDV
.. .. .: .:: :.::.:::::::::.::::::::::..:::::.::: : ..
XP_016 VSEQVSNGPVESVTLENSPLVWKEGRQLLRQYLEEVGYTDTILDMRSKRVRSLLGRSLEL
40 50 60 70 80 90
200 210 220 230
pF1KB5 TDREDDKN---------------QDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLE
. . .. .. .:. : ..:..: .. ..::: .. ::.
XP_016 NGAVEPSEGAPRAPPGPAGLSGGESLLVKQIEEQIKRNAAGKDGKERLGGSVLGQIPFLQ
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB5 SAAADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTKEALKEFDFLVTSEEGD
. . ::::.. : ..:. . . . . : :. :...:..::::: ..:.:.
XP_016 NCEDEDSDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSEDAINEFDFLGSGEDGE
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB5 NESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDML
.: : :. .:: : .:. . : ::: .:
XP_016 ----GAPD------------PRRCTVD-GSPHELESR---------------RVKLQGIL
220 230
360 370 380 390 400 410
pF1KB5 ANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEALE
:.::::: :: :.: .: :.. . :: .: :: ::: :
XP_016 ADLRDVDGLP---PKVTGPP-PGTPQPRPHE---------GSFGFSSD-VFIM--DTIGG
240 250 260 270 280
420 430 440 450 460 470
pF1KB5 SELGLGELAGLTVANEADSLTYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVL
.:..::.:: :::.:. : :. :....:::..::::::::::::.::::.:::: . .:
XP_016 GEVSLGDLADLTVTNDND-LSCDLSDSKDAFKKTWNPKFTLRSHYDGIRSLAFHHSQSAL
290 300 310 320 330 340
480 490 500 510 520 530
pF1KB5 ITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDG
.::::: :::.:::::.. :::...::::::..::::.:::: :.:.::.: :::::.:.
XP_016 LTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVAMGSNSEYCYSGGADA
350 360 370 380 390 400
540 550 560 570 580 590
pF1KB5 LIQGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNT
:..:. . ..::::.:::::: : :: :::::::.: . ::: :::::::.:.:.
XP_016 CIHSWKIPDLSMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDP
410 420 430 440 450 460
600 610 620 630 640 650
pF1KB5 TEVAPA-LSVFNDTKELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNV
. .:: : .: ..: :.:.:: ..:..:.:.:::: .: : ...::. . .:::::
XP_016 SSSSPACLCTFPTASEHGVPTSVAFTSTEPAHIVASFRSGDTVLYDMEVGSALLTLESR-
470 480 490 500 510 520
660 670 680 690 700 710
pF1KB5 DTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPN
... :::.:.:::. :..::::.:: :.: :: ::: .:::::::.::: ::::::
XP_016 --GSSGPTQINQVVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSMVAHLDAVTCLAVDPN
530 540 550 560 570
720 730 740 750 760 770
pF1KB5 GLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAK
: .:::::::::.:::.:..:::.::.:::::: ::.:: :: :::: :::::::::::
XP_016 GAFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACHPSKALIASAGADALAK
580 590 600 610 620 630
780
pF1KB5 VFV
:::
XP_016 VFV
640
>>XP_016882205 (OMIM: 614767) PREDICTED: striatin-4 isof (656 aa)
initn: 2037 init1: 750 opt: 1529 Z-score: 1153.6 bits: 224.0 E(85289): 1.6e-57
Smith-Waterman score: 1932; 48.0% identity (69.9% similar) in 708 aa overlap (104-780:1-656)
80 90 100 110 120 130
pF1KB5 RAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDMKPP
:::::::::::::::::.::.::::. :
XP_016 MLEYALKQERAKYHKLKFGTDLNQGEKKAD
10 20 30
140 150 160 170
pF1KB5 SYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYL---------------QEVGYTDTILDV
.. .. .: .:: :.::.::::::::: .::::::::::.
XP_016 VSEQVSNGPVESVTLENSPLVWKEGRQLLRQYLVKIYEAWLFISQGYLEEVGYTDTILDM
40 50 60 70 80 90
180 190 200 210 220
pF1KB5 KSKRVRALLGFSSDVTDREDDKN---------------QDSVVNGTEAEVKETAMIAKSE
.:::::.::: : ... . .. .. .:. : ..:..: ..
XP_016 RSKRVRSLLGRSLELNGAVEPSEGAPRAPPGPAGLSGGESLLVKQIEEQIKRNAAGKDGK
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB5 LTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTKE
..::: .. ::.. . ::::.. : ..:. . . . . : :. :...
XP_016 ERLGGSVLGQIPFLQNCEDEDSDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSED
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB5 ALKEFDFLVTSEEGDNESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGK
:..::::: ..:.:. .: : :. .:: : .:. .
XP_016 AINEFDFLGSGEDGE----GAPD------------PRRCTVD-GSPHELESR--------
220 230 240
350 360 370 380 390 400
pF1KB5 KGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPP
: ::: .::.::::: :: :.: .: :.. . :: .:
XP_016 -------RVKLQGILADLRDVDGLP---PKVTGPP-PGTPQPRPHE---------GSFGF
250 260 270 280
410 420 430 440 450 460
pF1KB5 SSGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALRKTWNPKFTLRSHF
:: ::: : .:..::.:: :::.:. : :. :....:::..::::::::::::.
XP_016 SSD-VFIM--DTIGGGEVSLGDLADLTVTNDND-LSCDLSDSKDAFKKTWNPKFTLRSHY
290 300 310 320 330 340
470 480 490 500 510 520
pF1KB5 DGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVV
::::.:::: . .:.::::: :::.:::::.. :::...::::::..::::.:::: :.
XP_016 DGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVA
350 360 370 380 390 400
530 540 550 560 570 580
pF1KB5 MSSNGEQCYSGGTDGLIQGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWGLAYSAAHQR
:.::.: :::::.:. :..:. . ..::::.:::::: : :: :::::::.: . ::
XP_016 MGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQR
410 420 430 440 450 460
590 600 610 620 630 640
pF1KB5 LLSCSADGTLRLWNTTEVAPA-LSVFNDTKELGIPASVDLVSSDPSHMVASFSKGYTSIF
: :::::::.:.:. . .:: : .: ..: :.:.:: ..:..:.:.:::: .: : ..
XP_016 LASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEPAHIVASFRSGDTVLY
470 480 490 500 510 520
650 660 670 680 690 700
pF1KB5 NMETQQRILTLESNVDTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSM
.::. . .::::: ... :::.:.:::. :..::::.:: :.: :: ::: .:::
XP_016 DMEVGSALLTLESR---GSSGPTQINQVVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSM
530 540 550 560 570
710 720 730 740 750 760
pF1KB5 VAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHP
::::.::: ::::::: .:::::::::.:::.:..:::.::.:::::: ::.:: :: ::
XP_016 VAHLDAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACHP
580 590 600 610 620 630
770 780
pF1KB5 SKCYIASAGADALAKVFV
:: ::::::::::::::
XP_016 SKALIASAGADALAKVFV
640 650
780 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:33:47 2016 done: Sun Nov 6 18:33:49 2016
Total Scan time: 11.130 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]