Result of FASTA (ccds) for
pFN21AB5785
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5785, 801 aa
1>>>pF1KB5785 801 - 801 aa - 801 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7028+/-0.000946; mu= 13.5713+/- 0.057
mean_var=85.5623+/-17.325, 0's: 0 Z-trim(107.2): 25 B-trim: 420 in 1/49
Lambda= 0.138654
statistics sampled from 9441 (9461) to 9441 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.291), width: 16
Scan time: 4.000
The best scores are: opt bits E(32554)
CCDS55638.1 PI4KB gene_id:5298|Hs108|chr1 ( 801) 5294 1069.2 0
CCDS81376.1 PI4KB gene_id:5298|Hs108|chr1 ( 816) 3315 673.3 4.3e-193
CCDS993.1 PI4KB gene_id:5298|Hs108|chr1 ( 828) 3315 673.3 4.3e-193
CCDS55637.1 PI4KB gene_id:5298|Hs108|chr1 ( 484) 3214 653.1 3.2e-187
CCDS33603.2 PI4KA gene_id:5297|Hs108|chr22 (2102) 661 142.5 6.7e-33
CCDS5739.1 PIK3CG gene_id:5294|Hs108|chr7 (1102) 428 95.9 4e-19
CCDS77180.1 PIK3C3 gene_id:5289|Hs108|chr18 ( 824) 414 93.0 2.1e-18
CCDS11920.1 PIK3C3 gene_id:5289|Hs108|chr18 ( 887) 414 93.1 2.3e-18
CCDS43171.1 PIK3CA gene_id:5290|Hs108|chr3 (1068) 415 93.3 2.3e-18
CCDS44839.1 PIK3C2G gene_id:5288|Hs108|chr12 (1445) 399 90.1 2.8e-17
CCDS73452.1 PIK3C2G gene_id:5288|Hs108|chr12 (1486) 399 90.1 2.9e-17
CCDS1446.1 PIK3C2B gene_id:5287|Hs108|chr1 (1634) 394 89.1 6.4e-17
CCDS7824.1 PIK3C2A gene_id:5286|Hs108|chr11 (1686) 388 87.9 1.5e-16
CCDS3104.1 PIK3CB gene_id:5291|Hs108|chr3 (1070) 379 86.1 3.4e-16
CCDS104.1 PIK3CD gene_id:5293|Hs108|chr1 (1044) 365 83.3 2.3e-15
>>CCDS55638.1 PI4KB gene_id:5298|Hs108|chr1 (801 aa)
initn: 5294 init1: 5294 opt: 5294 Z-score: 5719.8 bits: 1069.2 E(32554): 0
Smith-Waterman score: 5294; 100.0% identity (100.0% similar) in 801 aa overlap (1-801:1-801)
10 20 30 40 50 60
pF1KB5 MGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVGELSVIDPEVAQKACQEVLEKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVGELSVIDPEVAQKACQEVLEKVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LLHGGVAVSSRGTPLELVNGDGVDSEIRCLDDPPAQIREEEDEMGAAVASGTAKGARRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LLHGGVAVSSRGTPLELVNGDGVDSEIRCLDDPPAQIREEEDEMGAAVASGTAKGARRRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 QNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVEN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EDEPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EDEPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 HHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENRIRSTRSVENLPEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 HHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENRIRSTRSVENLPEC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 GITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCDNISQFSVDSITSQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCDNISQFSVDSITSQES
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 KEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEKVRRIREGSPYGHLPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEKVRRIREGSPYGHLPN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 WRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 WRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 AVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 AVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 NILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 GLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDG
730 740 750 760 770 780
790 800
pF1KB5 SMRSITTKLYDGFQYLTNGIM
:::::::::::::::::::::
CCDS55 SMRSITTKLYDGFQYLTNGIM
790 800
>>CCDS81376.1 PI4KB gene_id:5298|Hs108|chr1 (816 aa)
initn: 3304 init1: 3304 opt: 3315 Z-score: 3580.2 bits: 673.3 E(32554): 4.3e-193
Smith-Waterman score: 5254; 98.2% identity (98.2% similar) in 816 aa overlap (1-801:1-816)
10 20 30 40 50 60
pF1KB5 MGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVGELSVIDPEVAQKACQEVLEKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVGELSVIDPEVAQKACQEVLEKVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LLHGGVAVSSRGTPLELVNGDGVDSEIRCLDDPPAQIREEEDEMGAAVASGTAKGARRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LLHGGVAVSSRGTPLELVNGDGVDSEIRCLDDPPAQIREEEDEMGAAVASGTAKGARRRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 QNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 QNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 NMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVEN
250 260 270 280 290 300
310 320 330 340
pF1KB5 EDE---------------PVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLN
::: ::::::::::::::::::::::::::::::::::::::::::
CCDS81 EDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLN
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB5 HKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 HKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPE
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB5 NRIRSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 NRIRSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCD
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB5 NISQFSVDSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 NISQFSVDSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEK
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB5 VRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKI
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB5 LVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGY
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB5 CLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 CLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGG
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB5 LDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSM
730 740 750 760 770 780
770 780 790 800
pF1KB5 TEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
::::::::::::::::::::::::::::::::::::
CCDS81 TEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
790 800 810
>>CCDS993.1 PI4KB gene_id:5298|Hs108|chr1 (828 aa)
initn: 3304 init1: 3304 opt: 3315 Z-score: 3580.1 bits: 673.3 E(32554): 4.3e-193
Smith-Waterman score: 5254; 98.2% identity (98.2% similar) in 816 aa overlap (1-801:13-828)
10 20 30 40
pF1KB5 MGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVGELSVIDPEVA
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 MRFLEARSLAVAMGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVGELSVIDPEVA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 QKACQEVLEKVKLLHGGVAVSSRGTPLELVNGDGVDSEIRCLDDPPAQIREEEDEMGAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 QKACQEVLEKVKLLHGGVAVSSRGTPLELVNGDGVDSEIRCLDDPPAQIREEEDEMGAAV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 ASGTAKGARRRRQNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 ASGTAKGARRRRQNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 NEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 NEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQ
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB5 RHSRGTKLRKLILSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 RHSRGTKLRKLILSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSN
250 260 270 280 290 300
290 300 310 320 330
pF1KB5 LKRTASNPKVENEDE---------------PVRLAPEREFIKSLMAIGKRLATLPTKEQK
::::::::::::::: ::::::::::::::::::::::::::::::
CCDS99 LKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 TQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 TQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 FDTTSVPARIPENRIRSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 FDTTSVPARIPENRIRSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQ
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB5 VELPEVHTNSCDNISQFSVDSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 VELPEVHTNSCDNISQFSVDSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDP
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB5 SAVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 SAVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQ
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB5 ERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 ERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLS
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB5 AQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 AQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAF
670 680 690 700 710 720
700 710 720 730 740 750
pF1KB5 KLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 KLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSST
730 740 750 760 770 780
760 770 780 790 800
pF1KB5 IRNLKERFHMSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 IRNLKERFHMSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
790 800 810 820
>>CCDS55637.1 PI4KB gene_id:5298|Hs108|chr1 (484 aa)
initn: 3214 init1: 3214 opt: 3214 Z-score: 3474.8 bits: 653.1 E(32554): 3.2e-187
Smith-Waterman score: 3214; 100.0% identity (100.0% similar) in 484 aa overlap (318-801:1-484)
290 300 310 320 330 340
pF1KB5 NLKRTASNPKVENEDEPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHK
::::::::::::::::::::::::::::::
CCDS55 MAIGKRLATLPTKEQKTQRLISELSLLNHK
10 20 30
350 360 370 380 390 400
pF1KB5 LPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENR
40 50 60 70 80 90
410 420 430 440 450 460
pF1KB5 IRSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 IRSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCDNI
100 110 120 130 140 150
470 480 490 500 510 520
pF1KB5 SQFSVDSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SQFSVDSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEKVR
160 170 180 190 200 210
530 540 550 560 570 580
pF1KB5 RIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 RIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILV
220 230 240 250 260 270
590 600 610 620 630 640
pF1KB5 ISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCL
280 290 300 310 320 330
650 660 670 680 690 700
pF1KB5 VCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLD
340 350 360 370 380 390
710 720 730 740 750 760
pF1KB5 GDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTE
400 410 420 430 440 450
770 780 790 800
pF1KB5 EQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
::::::::::::::::::::::::::::::::::
CCDS55 EQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
460 470 480
>>CCDS33603.2 PI4KA gene_id:5297|Hs108|chr22 (2102 aa)
initn: 573 init1: 461 opt: 661 Z-score: 704.1 bits: 142.5 E(32554): 6.7e-33
Smith-Waterman score: 661; 39.3% identity (73.4% similar) in 267 aa overlap (536-800:1839-2100)
510 520 530 540 550 560
pF1KB5 FKRDPEDPSAVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLK
:. .:. ..: : ::: ::..::.:..
CCDS33 VKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQ--AAIFKVGDDCRQDMLALQIID
1810 1820 1830 1840 1850 1860
570 580 590 600 610 620
pF1KB5 QLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGS
...:.. . :.. ::.... . :.:: . . .: :. .:..... ::: ...:.
CCDS33 LFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGD
1870 1880 1890 1900 1910 1920
630 640 650 660 670 680
pF1KB5 YTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPR-
.: :: .:. ::..: :.: :. .:::.::::::::.:: .::::::::::.. :::
CCDS33 ESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGG
1930 1940 1950 1960 1970 1980
690 700 710 720 730 740
pF1KB5 NLGFETSAFKLTTEFVDVMGG-LDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGS
:::.: . .::: :.: .::: ... :... . ..: .:.: .:: ::..: .: . .
CCDS33 NLGWEPD-IKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLD-T
1990 2000 2010 2020 2030 2040
750 760 770 780 790 800
pF1KB5 QLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
::::.:. ::. ::.:: .:::.. .. ..... . : .. :: .:: : :
CCDS33 GLPCFRGQ-TIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSRTYDMIQYYQNDIPY
2050 2060 2070 2080 2090 2100
>>CCDS5739.1 PIK3CG gene_id:5294|Hs108|chr7 (1102 aa)
initn: 353 init1: 203 opt: 428 Z-score: 456.9 bits: 95.9 E(32554): 4e-19
Smith-Waterman score: 439; 24.1% identity (55.6% similar) in 626 aa overlap (217-800:495-1094)
190 200 210 220 230 240
pF1KB5 DEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDEL-
:....: :. .. ... :: :.
CCDS57 NLLLIDHRFLLRRGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYC
470 480 490 500 510 520
250 260 270 280 290 300
pF1KB5 KPAHRKRELPSLSPAPDT--GLSPSKRTHQRSKSDATASIS-LSSNLKRTASNPKVENED
.: .. :. .: : . :.. .: :: .. :... :. . . :.
CCDS57 HPIALPKHQPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLK
530 540 550 560 570 580
310 320 330 340 350 360
pF1KB5 EPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHH
.: . :. . : . :.. . : . ..: . . : :. : . : .:. .
CCDS57 HP-KAYPK---LFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLT--MQLLDCNFSDE
590 600 610 620 630
370 380 390 400 410
pF1KB5 VVRVPHTQAV-VLNSKDKAPYLIY-VEVLECENFDTTSVPARIPENRIRSTRSVENL---
::. .: . :.. : ::. :.... : . ... . . .:. : . :
CCDS57 NVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWF
640 650 660 670 680 690
420 430 440 450 460 470
pF1KB5 --PECGIT-HEQRAGSFSTV-PNYDNDDEAWSVDDIGELQVELPEVHTNSCDNISQFSVD
: . . : :. :... : . . :. . ::.. :. . .:...:..
CCDS57 LRSEIAQSRHYQQ--RFAVILEAYLRGCGTAMLHDFTQ-QVQVIEMLQKVTLDIKSLSAE
700 710 720 730 740 750
480 490 500 510
pF1KB5 S--ITSQESKEPVFIAAGDIRRRLSE-QLAHTPTAFKRDPEDPS----AVAL--------
. ..:: . ......: . : .. : .: : : ::. :.:.
CCDS57 KYDVSSQ--------VISQLKQKLENLQNSQLPESF-RVPYDPGLKAGALAIEKCKVMAS
760 770 780 790 800
520 530 540 550 560 570
pF1KB5 -KEP-WQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERV
:.: : : .. ..: . : : . ...: : ::::::..: .:.:. ..:::: : .
CCDS57 KKKPLWLE----FKCADPTA-LSN-ETIGIIFKHGDDLRQDMLILQILRIMESIWETESL
810 820 830 840 850 860
580 590 600 610 620
pF1KB5 PLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQS-------QLSLLDYFLQEHGSYTTE
: . :: . . :::: : .:..: ...... . .:...:.:. : : :
CCDS57 DLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEK-SPTEE
870 880 890 900 910
630 640 650 660 670 680
pF1KB5 AFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGF-
: .: . :: ::::::.. ..: . :::: ::.. :...::::: ::.. ::.
CCDS57 KFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGIN
920 930 940 950 960 970
690 700 710 720 730 740
pF1KB5 -ETSAFKLTTEFVDVMGGLD---GDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQ
: : :: .:. ::: . :. .. . ... .: :.: . .. . .: . .
CCDS57 KERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLM-TG
980 990 1000 1010 1020 1030
750 760 770 780 790 800
pF1KB5 LPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
.: . .. :. ... . .. .::. . .... . : .. : .:. ::
CCDS57 MPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGE
1040 1050 1060 1070 1080 1090
CCDS57 KHSA
1100
>>CCDS77180.1 PIK3C3 gene_id:5289|Hs108|chr18 (824 aa)
initn: 438 init1: 285 opt: 414 Z-score: 443.9 bits: 93.0 E(32554): 2.1e-18
Smith-Waterman score: 414; 27.1% identity (67.8% similar) in 258 aa overlap (546-795:570-821)
520 530 540 550 560 570
pF1KB5 VALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQER
:: : ::::::. : .:... .... ..:
CCDS77 GIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKEN
540 550 560 570 580 590
580 590 600 610 620 630
pF1KB5 VPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQ
. : . :::.:. :. :... ...: . .: ... :. ..: . : . .::.
CCDS77 LDLKLTPYKVLATSTKHGFMQ-FIQSVPVAEVL-DTEGSIQNFFRKYAPSENGPNGISAE
600 610 620 630 640 650
640 650 660 670 680 690
pF1KB5 --RNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAF
..:.::::::.. :.: : ::: :.:: :...:::::.::. .:. : .
CCDS77 VMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPL---PPPM
660 670 680 690 700 710
700 710 720 730 740 750
pF1KB5 KLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLP--CFHGS
::. :.:. ::: ...... .. ... :.. . .... .: ... .: .. .
CCDS77 KLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDAN-IPDIALEPD
720 730 740 750 760 770
760 770 780 790 800
pF1KB5 STIRNLKERFHMSMTEEQ----LQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
.:.......:......:. .: :... : . . ... ... ::
CCDS77 KTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK
780 790 800 810 820
>>CCDS11920.1 PIK3C3 gene_id:5289|Hs108|chr18 (887 aa)
initn: 438 init1: 285 opt: 414 Z-score: 443.3 bits: 93.1 E(32554): 2.3e-18
Smith-Waterman score: 414; 27.1% identity (67.8% similar) in 258 aa overlap (546-795:633-884)
520 530 540 550 560 570
pF1KB5 VALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQER
:: : ::::::. : .:... .... ..:
CCDS11 GIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKEN
610 620 630 640 650 660
580 590 600 610 620 630
pF1KB5 VPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQ
. : . :::.:. :. :... ...: . .: ... :. ..: . : . .::.
CCDS11 LDLKLTPYKVLATSTKHGFMQ-FIQSVPVAEVL-DTEGSIQNFFRKYAPSENGPNGISAE
670 680 690 700 710 720
640 650 660 670 680 690
pF1KB5 --RNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAF
..:.::::::.. :.: : ::: :.:: :...:::::.::. .:. : .
CCDS11 VMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPL---PPPM
730 740 750 760 770
700 710 720 730 740 750
pF1KB5 KLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLP--CFHGS
::. :.:. ::: ...... .. ... :.. . .... .: ... .: .. .
CCDS11 KLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDAN-IPDIALEPD
780 790 800 810 820 830
760 770 780 790 800
pF1KB5 STIRNLKERFHMSMTEEQ----LQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
.:.......:......:. .: :... : . . ... ... ::
CCDS11 KTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK
840 850 860 870 880
>>CCDS43171.1 PIK3CA gene_id:5290|Hs108|chr3 (1068 aa)
initn: 320 init1: 179 opt: 415 Z-score: 443.1 bits: 93.3 E(32554): 2.3e-18
Smith-Waterman score: 415; 29.6% identity (64.2% similar) in 260 aa overlap (546-789:799-1055)
520 530 540 550 560 570
pF1KB5 VALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQER
.: : ::::::..:..:... ...::...
CCDS43 CRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQG
770 780 790 800 810 820
580 590 600 610 620
pF1KB5 VPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLS--------LLDYFLQEHGSYT
. : . :: : :. :.:: : :. .: :.. .. :. : .:.....
CCDS43 LDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNK--
830 840 850 860 870 880
630 640 650 660 670 680
pF1KB5 TEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLG
: . .: :..::::::.. ..: . ::::.::.. .:...::::: .:. . ...:
CCDS43 GEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFG
890 900 910 920 930 940
690 700 710 720 730 740
pF1KB5 F--ETSAFKLTTEFVDVM--GGLDGDM---FNYYKMLMLQGLIAARKHMDKVVQIVEIMQ
. : : :: .:. :. :. . :. .. . .. .: :.: . ... .:
CCDS43 YKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMML
950 960 970 980 990 1000
750 760 770 780 790
pF1KB5 QGSQLPCFHGSSTIRNLKERFHMSMTE-EQLQLLVEQMVDGSMRSITTKLYDGFQYLTNG
:: .: ... . : ... . .. :: : :. ...:: :. . :::.
CCDS43 -GSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQH
1010 1020 1030 1040 1050 1060
800
pF1KB5 IM
CCDS43 ALN
>>CCDS44839.1 PIK3C2G gene_id:5288|Hs108|chr12 (1445 aa)
initn: 338 init1: 194 opt: 399 Z-score: 423.6 bits: 90.1 E(32554): 2.8e-17
Smith-Waterman score: 399; 31.3% identity (64.3% similar) in 230 aa overlap (539-758:911-1135)
510 520 530 540 550 560
pF1KB5 DPEDPSAVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQ
: . .:.: : ::::::..:..:... ..
CCDS44 ALCIKGIDHDACSYFTSNALPLKITFINANPMGKNISIIFKAGDDLRQDMLVLQLIQVMD
890 900 910 920 930 940
570 580 590 600 610 620
pF1KB5 SIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQL------SLLDYFLQE
.:: :: . . . :. : . :.:... : .::.. .....: : . . ....
CCDS44 NIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLAKIHRHSGLIGPLKENTIKKWFSQ
950 960 970 980 990 1000
630 640 650 660 670 680
pF1KB5 HGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSS
:. .. . .: ::: ::::.:.: ..: : :::: ::.: ::..::::: .:. .
CCDS44 HNHLKAD-YEKALRNFFYSCAGWCVVTFILGVCDRHNDNIMLTKSGHMFHIDFGKFLGHA
1010 1020 1030 1040 1050
690 700 710 720 730
pF1KB5 PRNLGF--ETSAFKLTTE--FVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEI
:. . . : .:.: . . :: . . :. . : .. ::: . .....:.
CCDS44 QTFGGIKRDRAPFIFTSEMEYFITEGGKNPQHFQDFVELCCRAYNIIRKHSQLLLNLLEM
1060 1070 1080 1090 1100 1110
740 750 760 770 780 790
pF1KB5 MQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTN
: .. :: . : :..::
CCDS44 MLYAG-LPELSG---IQDLKYVYNNLRPQDTDLEATSHFTKKIKESLECFPVKLNNLIHT
1120 1130 1140 1150 1160 1170
801 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:47:22 2016 done: Mon Nov 7 03:47:23 2016
Total Scan time: 4.000 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]