Result of FASTA (omim) for
pFN21AB5783
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5783, 695 aa
1>>>pF1KB5783 695 - 695 aa - 695 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.8780+/-0.000422; mu= -14.6228+/- 0.026
mean_var=378.5678+/-76.853, 0's: 0 Z-trim(122.4): 70 B-trim: 36 in 1/55
Lambda= 0.065918
statistics sampled from 40458 (40538) to 40458 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.475), width: 16
Scan time: 15.030
The best scores are: opt bits E(85289)
NP_001626 (OMIM: 600418) amphiphysin isoform 1 [Ho ( 695) 4575 449.2 2.4e-125
NP_647477 (OMIM: 600418) amphiphysin isoform 2 [Ho ( 653) 2875 287.6 1.1e-76
XP_006715754 (OMIM: 600418) PREDICTED: amphiphysin ( 392) 2576 259.0 2.5e-68
XP_006715753 (OMIM: 600418) PREDICTED: amphiphysin ( 819) 2583 259.8 2.9e-68
XP_011513573 (OMIM: 600418) PREDICTED: amphiphysin ( 861) 2583 259.9 3.1e-68
XP_016867485 (OMIM: 600418) PREDICTED: amphiphysin ( 921) 2583 259.9 3.2e-68
XP_006715752 (OMIM: 600418) PREDICTED: amphiphysin (1225) 2583 259.9 4.1e-68
XP_016867484 (OMIM: 600418) PREDICTED: amphiphysin (1267) 2583 259.9 4.2e-68
NP_001307570 (OMIM: 255200,601248) myc box-depende ( 562) 1599 166.2 3.1e-40
XP_016859309 (OMIM: 255200,601248) PREDICTED: myc ( 518) 1546 161.1 9.6e-39
XP_006712490 (OMIM: 255200,601248) PREDICTED: myc ( 538) 1528 159.4 3.3e-38
XP_016859311 (OMIM: 255200,601248) PREDICTED: myc ( 452) 1474 154.2 9.9e-37
NP_647598 (OMIM: 255200,601248) myc box-dependent- ( 482) 1462 153.1 2.3e-36
NP_647597 (OMIM: 255200,601248) myc box-dependent- ( 518) 1461 153.0 2.6e-36
XP_016859313 (OMIM: 255200,601248) PREDICTED: myc ( 428) 1403 147.5 1e-34
NP_647599 (OMIM: 255200,601248) myc box-dependent- ( 475) 1246 132.6 3.5e-30
NP_647600 (OMIM: 255200,601248) myc box-dependent- ( 439) 1235 131.5 6.7e-30
NP_647601 (OMIM: 255200,601248) myc box-dependent- ( 409) 1232 131.2 7.7e-30
XP_016859312 (OMIM: 255200,601248) PREDICTED: myc ( 451) 1175 125.8 3.6e-28
XP_016859315 (OMIM: 255200,601248) PREDICTED: myc ( 415) 1164 124.7 6.9e-28
NP_001307563 (OMIM: 255200,601248) myc box-depende ( 385) 1161 124.4 7.9e-28
XP_005263700 (OMIM: 255200,601248) PREDICTED: myc ( 577) 1155 124.0 1.6e-27
NP_001307561 (OMIM: 255200,601248) myc box-depende ( 424) 1142 122.7 3e-27
NP_004296 (OMIM: 255200,601248) myc box-dependent- ( 454) 1141 122.6 3.4e-27
NP_647596 (OMIM: 255200,601248) myc box-dependent- ( 497) 1140 122.5 3.9e-27
XP_005263702 (OMIM: 255200,601248) PREDICTED: myc ( 553) 1084 117.2 1.7e-25
XP_005269014 (OMIM: 605936) PREDICTED: bridging in ( 564) 1005 109.7 3.2e-23
NP_057377 (OMIM: 605936) bridging integrator 2 iso ( 597) 984 107.7 1.3e-22
XP_005269015 (OMIM: 605936) PREDICTED: bridging in ( 570) 980 107.3 1.7e-22
NP_001276936 (OMIM: 605936) bridging integrator 2 ( 539) 901 99.8 2.9e-20
NP_647593 (OMIM: 255200,601248) myc box-dependent- ( 593) 836 93.6 2.3e-18
XP_016859310 (OMIM: 255200,601248) PREDICTED: myc ( 483) 812 91.3 9.4e-18
NP_001307569 (OMIM: 255200,601248) myc box-depende ( 513) 802 90.4 1.9e-17
XP_016859317 (OMIM: 255200,601248) PREDICTED: myc ( 369) 785 88.7 4.4e-17
XP_016859316 (OMIM: 255200,601248) PREDICTED: myc ( 384) 785 88.7 4.6e-17
XP_006712497 (OMIM: 255200,601248) PREDICTED: myc ( 440) 785 88.7 5.1e-17
XP_006712496 (OMIM: 255200,601248) PREDICTED: myc ( 455) 785 88.7 5.3e-17
NP_001307562 (OMIM: 255200,601248) myc box-depende ( 470) 785 88.7 5.4e-17
XP_006712495 (OMIM: 255200,601248) PREDICTED: myc ( 485) 785 88.7 5.6e-17
XP_006712494 (OMIM: 255200,601248) PREDICTED: myc ( 498) 785 88.7 5.7e-17
NP_647595 (OMIM: 255200,601248) myc box-dependent- ( 506) 785 88.7 5.8e-17
XP_006712492 (OMIM: 255200,601248) PREDICTED: myc ( 521) 785 88.8 5.9e-17
XP_006712491 (OMIM: 255200,601248) PREDICTED: myc ( 528) 785 88.8 6e-17
NP_647594 (OMIM: 255200,601248) myc box-dependent- ( 550) 785 88.8 6.2e-17
XP_006712488 (OMIM: 255200,601248) PREDICTED: myc ( 564) 785 88.8 6.3e-17
XP_006712489 (OMIM: 255200,601248) PREDICTED: myc ( 564) 785 88.8 6.3e-17
XP_005263699 (OMIM: 255200,601248) PREDICTED: myc ( 608) 785 88.8 6.7e-17
NP_001307571 (OMIM: 255200,601248) myc box-depende ( 566) 759 86.3 3.5e-16
XP_016859314 (OMIM: 255200,601248) PREDICTED: myc ( 416) 714 82.0 5.3e-15
XP_016859308 (OMIM: 255200,601248) PREDICTED: myc ( 584) 714 82.0 7e-15
>>NP_001626 (OMIM: 600418) amphiphysin isoform 1 [Homo s (695 aa)
initn: 4575 init1: 4575 opt: 4575 Z-score: 2371.4 bits: 449.2 E(85289): 2.4e-125
Smith-Waterman score: 4575; 100.0% identity (100.0% similar) in 695 aa overlap (1-695:1-695)
10 20 30 40 50 60
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
610 620 630 640 650 660
670 680 690
pF1KB5 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
:::::::::::::::::::::::::::::::::::
NP_001 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
670 680 690
>>NP_647477 (OMIM: 600418) amphiphysin isoform 2 [Homo s (653 aa)
initn: 2868 init1: 2829 opt: 2875 Z-score: 1498.0 bits: 287.6 E(85289): 1.1e-76
Smith-Waterman score: 4213; 94.0% identity (94.0% similar) in 695 aa overlap (1-695:1-653)
10 20 30 40 50 60
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL
:::: ::::::::::::::
NP_647 ICNL------------------------------------------IIPGADADAAVGTL
430
490 500 510 520 530 540
pF1KB5 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB5 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB5 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
560 570 580 590 600 610
670 680 690
pF1KB5 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
:::::::::::::::::::::::::::::::::::
NP_647 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
620 630 640 650
>>XP_006715754 (OMIM: 600418) PREDICTED: amphiphysin iso (392 aa)
initn: 2576 init1: 2576 opt: 2576 Z-score: 1347.8 bits: 259.0 E(85289): 2.5e-68
Smith-Waterman score: 2576; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386)
10 20 30 40 50 60
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
::::::::::::::::::::::::::
XP_006 PEVTPAGSAGVTHSPMSQTLPWDLWTKEDTYI
370 380 390
>>XP_006715753 (OMIM: 600418) PREDICTED: amphiphysin iso (819 aa)
initn: 4048 init1: 2583 opt: 2583 Z-score: 1346.5 bits: 259.8 E(85289): 2.9e-68
Smith-Waterman score: 3284; 76.5% identity (79.9% similar) in 727 aa overlap (1-603:1-727)
10 20 30 40 50 60
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
310 320 330 340 350 360
370 380 390
pF1KB5 PEVTPAGSAGVTHSPMSQTLPWDLWTTST-------DLVQ---PASG------------G
:::::::::::::::::::::::::::.. .:.. : :: :
XP_006 PEVTPAGSAGVTHSPMSQTLPWDLWTTDSSESLSLCNLIMEETPDSGLAEEIQRSQNDIG
370 380 390 400 410 420
400 410 420 430
pF1KB5 SFN-----------------GFTQ----P----QDTSLFTMQTDQSMICNLAE-SEQAP-
.:. :: . : :: : : ... ..:: ::.::
XP_006 AFTWGPDASTDRVSQEVTSGGFGEDSACPSETEQDIRLSTSLLSSADWPTVAEESEHAPG
430 440 450 460 470 480
440 450
pF1KB5 ----------PTEPKAE---------------EPLAAVTPAV---GL------DLGMDTR
: .: : .:: . ::. :: :. . .
XP_006 PAFPGGNEQLPPKPAPEAGVAIAACVEMEQLYDPLDSDMPAMDTAGLFKESHEDMKKSDE
490 500 510 520 530 540
460 470
pF1KB5 AEEP--VEEAV---------------------------------------IIPGADADAA
:: .:... ::::::::::
XP_006 EEEKQKMEDSLWAGVEACQKASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAA
550 560 570 580 590 600
480 490 500 510 520 530
pF1KB5 VGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQ
610 620 630 640 650 660
540 550 560 570 580 590
pF1KB5 EKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQP
670 680 690 700 710 720
600 610 620 630 640 650
pF1KB5 TPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDS
:::::::
XP_006 TPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDS
730 740 750 760 770 780
>--
initn: 609 init1: 609 opt: 609 Z-score: 331.9 bits: 72.1 E(85289): 9.5e-12
Smith-Waterman score: 609; 100.0% identity (100.0% similar) in 92 aa overlap (604-695:728-819)
580 590 600 610 620 630
pF1KB5 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF
::::::::::::::::::::::::::::::
XP_006 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF
700 710 720 730 740 750
640 650 660 670 680 690
pF1KB5 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR
760 770 780 790 800 810
pF1KB5 LD
::
XP_006 LD
>>XP_011513573 (OMIM: 600418) PREDICTED: amphiphysin iso (861 aa)
initn: 4524 init1: 2583 opt: 2583 Z-score: 1346.1 bits: 259.9 E(85289): 3.1e-68
Smith-Waterman score: 3307; 76.9% identity (76.9% similar) in 727 aa overlap (1-561:1-727)
10 20 30 40 50 60
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
310 320 330 340 350 360
370 380
pF1KB5 PEVTPAGSAGVTHSPMSQTLPWDLWTT---------------------------------
:::::::::::::::::::::::::::
XP_011 PEVTPAGSAGVTHSPMSQTLPWDLWTTDSSESLSLCNLIMEETPDSGLAEEIQRSQNDIG
370 380 390 400 410 420
390
pF1KB5 --------STDLV-----------------------------------------------
::: :
XP_011 AFTWGPDASTDRVSQEVTSGGFGEDSACPSETEQDIRLSTSLLSSADWPTVAEESEHAPG
430 440 450 460 470 480
pF1KB5 ------------------------------------------------------------
XP_011 PAFPGGNEQLPPKPAPEAGVAIAACVEMEQLYDPLDSDMPAMDTAGLFKESHEDMKKSDE
490 500 510 520 530 540
400 410 420 430
pF1KB5 ------------------QPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTE
: ::::::::::::::::::::::::::::::::::::::::
XP_011 EEEKQKMEDSLWAGVEACQKASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTE
550 560 570 580 590 600
440 450 460 470 480 490
pF1KB5 PKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEA
610 620 630 640 650 660
500 510 520 530 540 550
pF1KB5 EKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEE
670 680 690 700 710 720
560 570 580 590 600 610
pF1KB5 GENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASARE
:::::::
XP_011 GENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASARE
730 740 750 760 770 780
>--
initn: 897 init1: 897 opt: 897 Z-score: 479.6 bits: 99.5 E(85289): 5.6e-20
Smith-Waterman score: 897; 100.0% identity (100.0% similar) in 134 aa overlap (562-695:728-861)
540 550 560 570 580 590
pF1KB5 ATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPI
::::::::::::::::::::::::::::::
XP_011 ATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPI
700 710 720 730 740 750
600 610 620 630 640 650
pF1KB5 QDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLV
760 770 780 790 800 810
660 670 680 690
pF1KB5 VPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
820 830 840 850 860
>>XP_016867485 (OMIM: 600418) PREDICTED: amphiphysin iso (921 aa)
initn: 4048 init1: 2583 opt: 2583 Z-score: 1345.7 bits: 259.9 E(85289): 3.2e-68
Smith-Waterman score: 2585; 92.3% identity (94.6% similar) in 429 aa overlap (1-419:1-429)
10 20 30 40 50 60
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 PEVTPAGSAGVTHSPMSQTLPWDLWTTST-------DLVQ---PASGGSFNGFTQPQDTS
:::::::::::::::::::::::::::.. .:.. : :: . . . .: .
XP_016 PEVTPAGSAGVTHSPMSQTLPWDLWTTDSSESLSLCNLIMEETPDSGLAEEIQRSQNDIG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 LFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPG
:: : :
XP_016 AFTWGPDASTDRVSQEVTSGGFGEDSACPSETEQDIRLSTSLLSSADWPTVAEESEHAPG
430 440 450 460 470 480
>--
initn: 1498 init1: 1479 opt: 1479 Z-score: 778.3 bits: 154.9 E(85289): 1.3e-36
Smith-Waterman score: 1601; 85.3% identity (85.6% similar) in 306 aa overlap (390-695:658-921)
360 370 380 390 400 410
pF1KB5 KPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQS
: .: :::::::::::::::::::::::::
XP_016 NYFEKTDLLEKDMEGGDMAKELSDRDQGLHDGIQKASGGSFNGFTQPQDTSLFTMQTDQS
630 640 650 660 670 680
420 430 440 450 460 470
pF1KB5 MICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGT
::::: :::::::::::::
XP_016 MICNL------------------------------------------IIPGADADAAVGT
690 700
480 490 500 510 520 530
pF1KB5 LVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKV
710 720 730 740 750 760
540 550 560 570 580 590
pF1KB5 IPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPS
770 780 790 800 810 820
600 610 620 630 640 650
pF1KB5 APAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEAD
830 840 850 860 870 880
660 670 680 690
pF1KB5 QDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
::::::::::::::::::::::::::::::::::::
XP_016 QDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
890 900 910 920
>>XP_006715752 (OMIM: 600418) PREDICTED: amphiphysin iso (1225 aa)
initn: 4048 init1: 2583 opt: 2583 Z-score: 1343.8 bits: 259.9 E(85289): 4.1e-68
Smith-Waterman score: 2585; 92.3% identity (94.6% similar) in 429 aa overlap (1-419:1-429)
10 20 30 40 50 60
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 PEVTPAGSAGVTHSPMSQTLPWDLWTTST-------DLVQ---PASGGSFNGFTQPQDTS
:::::::::::::::::::::::::::.. .:.. : :: . . . .: .
XP_006 PEVTPAGSAGVTHSPMSQTLPWDLWTTDSSESLSLCNLIMEETPDSGLAEEIQRSQNDIG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 LFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPG
:: : :
XP_006 AFTWGPDASTDRVSQEVTSGGFGEDSACPSETEQDIRLSTSLLSSADWPTVAEESEHAPG
430 440 450 460 470 480
>--
initn: 1498 init1: 1479 opt: 1493 Z-score: 783.6 bits: 156.3 E(85289): 6.6e-37
Smith-Waterman score: 1587; 86.0% identity (86.0% similar) in 301 aa overlap (395-695:967-1225)
370 380 390 400 410 420
pF1KB5 PAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNL
::::::::::::::::::::::::::::::
XP_006 DINNSDLSEDEIANQRYGLLYQEIEADKDEASGGSFNGFTQPQDTSLFTMQTDQSMICNL
940 950 960 970 980 990
430 440 450 460 470 480
pF1KB5 AESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAA
::::::::::::::::::
XP_006 ------------------------------------------IIPGADADAAVGTLVSAA
1000 1010
490 500 510 520 530 540
pF1KB5 EGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVV
1020 1030 1040 1050 1060 1070
550 560 570 580 590 600
pF1KB5 IEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMG
1080 1090 1100 1110 1120 1130
610 620 630 640 650 660
pF1KB5 AADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGW
1140 1150 1160 1170 1180 1190
670 680 690
pF1KB5 LVGVKESDWLQYRDLATYKGLFPENFTRRLD
:::::::::::::::::::::::::::::::
XP_006 LVGVKESDWLQYRDLATYKGLFPENFTRRLD
1200 1210 1220
>>XP_016867484 (OMIM: 600418) PREDICTED: amphiphysin iso (1267 aa)
initn: 4518 init1: 2583 opt: 2583 Z-score: 1343.6 bits: 259.9 E(85289): 4.2e-68
Smith-Waterman score: 2585; 92.3% identity (94.6% similar) in 429 aa overlap (1-419:1-429)
10 20 30 40 50 60
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 PEVTPAGSAGVTHSPMSQTLPWDLWTTST-------DLVQ---PASGGSFNGFTQPQDTS
:::::::::::::::::::::::::::.. .:.. : :: . . . .: .
XP_016 PEVTPAGSAGVTHSPMSQTLPWDLWTTDSSESLSLCNLIMEETPDSGLAEEIQRSQNDIG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 LFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPG
:: : :
XP_016 AFTWGPDASTDRVSQEVTSGGFGEDSACPSETEQDIRLSTSLLSSADWPTVAEESEHAPG
430 440 450 460 470 480
>--
initn: 1949 init1: 1949 opt: 1949 Z-score: 1017.7 bits: 199.6 E(85289): 6e-50
Smith-Waterman score: 1949; 100.0% identity (100.0% similar) in 301 aa overlap (395-695:967-1267)
370 380 390 400 410 420
pF1KB5 PAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNL
::::::::::::::::::::::::::::::
XP_016 DINNSDLSEDEIANQRYGLLYQEIEADKDEASGGSFNGFTQPQDTSLFTMQTDQSMICNL
940 950 960 970 980 990
430 440 450 460 470 480
pF1KB5 AESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAA
1000 1010 1020 1030 1040 1050
490 500 510 520 530 540
pF1KB5 EGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVV
1060 1070 1080 1090 1100 1110
550 560 570 580 590 600
pF1KB5 IEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMG
1120 1130 1140 1150 1160 1170
610 620 630 640 650 660
pF1KB5 AADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGW
1180 1190 1200 1210 1220 1230
670 680 690
pF1KB5 LVGVKESDWLQYRDLATYKGLFPENFTRRLD
:::::::::::::::::::::::::::::::
XP_016 LVGVKESDWLQYRDLATYKGLFPENFTRRLD
1240 1250 1260
>>NP_001307570 (OMIM: 255200,601248) myc box-dependent-i (562 aa)
initn: 1887 init1: 1168 opt: 1599 Z-score: 843.2 bits: 166.2 E(85289): 3.1e-40
Smith-Waterman score: 1757; 45.5% identity (65.5% similar) in 695 aa overlap (4-694:9-561)
10 20 30 40 50
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTR
. .: .:.::::.:.::::::::::::::::::::::. ::::..: .::::
NP_001 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVD
::..:: :::..:.:.::: ::.: :.::::::: ::.... ..:. :.:: :.::::::
NP_001 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQK
.:::.:::::::::::.:::::.:::::::::::: :.::..:.:::..:.:::::. :
NP_001 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 AQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLG
:::::::.::::::::::::. :::::::::.....:: .::::.. : ..: .:.. :
NP_001 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 DQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPA---SPAPARPR
::....::... :::..: . :.::::. :: .: :: :: .:. . :.
NP_001 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPD-GSPAATPEIRVNHEPEPAGGATPGATLPK
250 260 270 280 290
300 310 320 330 340 350
pF1KB5 SPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVP-EVKKEETL
:::: :::::::: :: ::.::..::.:.:.:::.:::::::::::: :.: ... .:
NP_001 SPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 LDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSL
:::::::. : ..:. . .: .:..::::: . . :: ::.
NP_001 LDLDFDPLPPVTSPVKAP----TPSGQSIPWDLWEPTES---PA--GSL-----------
360 370 380 390
420 430 440 450 460 470
pF1KB5 FTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGA
: ::.: : ::. : . : ::
NP_001 -------------------PSGEPSAAEGTFAVS--------------WPSQTAE--PG-
400 410 420
480 490 500 510 520 530
pF1KB5 DADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELE
:.. ::: .. :: ::. . ::.
NP_001 ----------------PAQPAEASEV---AG----------GTQPAAGAQ----------
430 440
540 550 560 570 580 590
pF1KB5 ATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPI
:: :: :: . .: : ...: :
NP_001 --------------------------------EPGET---AASEAASSSLPAVVVETFP-
450 460
600 610 620 630 640 650
pF1KB5 QDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLV
: . :... ..: . .:::::..::.. ::. :...::: :. ::::::
NP_001 --------ATVNGTVEGGSGA--GRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLV
470 480 490 500 510
660 670 680 690
pF1KB5 VPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
.: .. .:: :::.::::::: :...: .:.::::::.:.
NP_001 IPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
520 530 540 550 560
>>XP_016859309 (OMIM: 255200,601248) PREDICTED: myc box- (518 aa)
initn: 1859 init1: 1168 opt: 1546 Z-score: 816.5 bits: 161.1 E(85289): 9.6e-39
Smith-Waterman score: 1583; 43.3% identity (61.0% similar) in 695 aa overlap (4-694:9-517)
10 20 30 40 50
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTR
. .: .:.::::.:.::::::::::::::::::::::. ::::..: .::::
XP_016 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVD
::..:: :::..:.:.::: ::.: :.::::::: ::.... ..:. :.:: :.::::::
XP_016 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQK
.:::.:::::::::::.:::::.:::::::::::: :.::..:.:::..:.:::::. :
XP_016 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 AQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLG
:::::::.::::::::::::. :::::::::.....:: .::::.. : ..: .:.. :
XP_016 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 DQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPA---SPAPARPR
::....::... :::..: . :.::::. :: .: :: :: .:. . :.
XP_016 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPD-GSPAATPEIRVNHEPEPAGGATPGATLPK
250 260 270 280 290
300 310 320 330 340 350
pF1KB5 SPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVP-EVKKEETL
:::: :::::::: :: ::.::..::.:.:.:::.:::::::::::: :.: ... .:
XP_016 SPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 LDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSL
:::::::. : :: ::.. : ::: .. : :::
XP_016 LDLDFDPL-PPVT---------SPVKAPTPSG---------QPAEASEVAGGTQP-----
360 370 380 390
420 430 440 450 460 470
pF1KB5 FTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGA
:.: :.::
XP_016 -----------------------------------AAG--------AQEP----------
400
480 490 500 510 520 530
pF1KB5 DADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELE
:: : .: :.
XP_016 -----------------GETAASEAAS---------------------------------
410
540 550 560 570 580 590
pF1KB5 ATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPI
. .:.::.: :. : . :.: .. :
XP_016 ------SSLPAVVVE-------------TFPATVNGTVEGGSGAG---------------
420 430
600 610 620 630 640 650
pF1KB5 QDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLV
.:::::..::.. ::. :...::: :. ::::::
XP_016 ------------------------RLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLV
440 450 460 470
660 670 680 690
pF1KB5 VPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
.: .. .:: :::.::::::: :...: .:.::::::.:.
XP_016 IPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
480 490 500 510
695 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:59:34 2016 done: Mon Nov 7 15:59:37 2016
Total Scan time: 15.030 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]