Result of FASTA (ccds) for
pFN21AB5783
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5783, 695 aa
1>>>pF1KB5783 695 - 695 aa - 695 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.5144+/-0.00107; mu= -6.0036+/- 0.065
mean_var=336.1786+/-67.152, 0's: 0 Z-trim(114.5): 31 B-trim: 0 in 0/53
Lambda= 0.069950
statistics sampled from 15031 (15060) to 15031 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.463), width: 16
Scan time: 4.790
The best scores are: opt bits E(32554)
CCDS5456.1 AMPH gene_id:273|Hs108|chr7 ( 695) 4575 475.5 1.1e-133
CCDS47574.1 AMPH gene_id:273|Hs108|chr7 ( 653) 2875 303.9 4.7e-82
CCDS42744.1 BIN1 gene_id:274|Hs108|chr2 ( 482) 1462 161.3 3.1e-39
CCDS2142.1 BIN1 gene_id:274|Hs108|chr2 ( 518) 1461 161.2 3.5e-39
CCDS42743.1 BIN1 gene_id:274|Hs108|chr2 ( 475) 1246 139.5 1.1e-32
CCDS46403.1 BIN1 gene_id:274|Hs108|chr2 ( 439) 1235 138.3 2.3e-32
CCDS2143.1 BIN1 gene_id:274|Hs108|chr2 ( 409) 1232 138.0 2.6e-32
CCDS82508.1 BIN1 gene_id:274|Hs108|chr2 ( 424) 1142 128.9 1.5e-29
CCDS2137.1 BIN1 gene_id:274|Hs108|chr2 ( 454) 1141 128.9 1.7e-29
CCDS2141.1 BIN1 gene_id:274|Hs108|chr2 ( 497) 1140 128.8 1.9e-29
CCDS8811.2 BIN2 gene_id:51411|Hs108|chr12 ( 597) 984 113.1 1.2e-24
CCDS76561.1 BIN2 gene_id:51411|Hs108|chr12 ( 539) 901 104.7 3.7e-22
CCDS2138.1 BIN1 gene_id:274|Hs108|chr2 ( 593) 836 98.2 3.8e-20
CCDS2140.1 BIN1 gene_id:274|Hs108|chr2 ( 506) 785 93.0 1.2e-18
CCDS2139.1 BIN1 gene_id:274|Hs108|chr2 ( 550) 785 93.0 1.3e-18
>>CCDS5456.1 AMPH gene_id:273|Hs108|chr7 (695 aa)
initn: 4575 init1: 4575 opt: 4575 Z-score: 2513.4 bits: 475.5 E(32554): 1.1e-133
Smith-Waterman score: 4575; 100.0% identity (100.0% similar) in 695 aa overlap (1-695:1-695)
10 20 30 40 50 60
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
610 620 630 640 650 660
670 680 690
pF1KB5 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
:::::::::::::::::::::::::::::::::::
CCDS54 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
670 680 690
>>CCDS47574.1 AMPH gene_id:273|Hs108|chr7 (653 aa)
initn: 2868 init1: 2829 opt: 2875 Z-score: 1586.6 bits: 303.9 E(32554): 4.7e-82
Smith-Waterman score: 4213; 94.0% identity (94.0% similar) in 695 aa overlap (1-695:1-653)
10 20 30 40 50 60
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL
:::: ::::::::::::::
CCDS47 ICNL------------------------------------------IIPGADADAAVGTL
430
490 500 510 520 530 540
pF1KB5 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB5 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB5 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
560 570 580 590 600 610
670 680 690
pF1KB5 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
:::::::::::::::::::::::::::::::::::
CCDS47 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
620 630 640 650
>>CCDS42744.1 BIN1 gene_id:274|Hs108|chr2 (482 aa)
initn: 1788 init1: 1155 opt: 1462 Z-score: 817.9 bits: 161.3 E(32554): 3.1e-39
Smith-Waterman score: 1462; 63.3% identity (86.1% similar) in 346 aa overlap (4-345:9-353)
10 20 30 40 50
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTR
. .: .:.::::.:.::::::::::::::::::::::. ::::..: .::::
CCDS42 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVD
::..:: :::..:.:.::: ::.: :.::::::: ::.... ..:. :.:: :.::::::
CCDS42 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQK
.:::.:::::::::::.:::::.:::::::::::: :.::..:.:::..:.:::::. :
CCDS42 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 AQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLG
:::::::.::::::::::::. :::::::::.....:: .::::.. : ..: .:.. :
CCDS42 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 DQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPA---SPAPARPR
::....::... :::..: . :.::::. :: .: :: :: .:. . :.
CCDS42 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPD-GSPAATPEIRVNHEPEPAGGATPGATLPK
250 260 270 280 290
300 310 320 330 340 350
pF1KB5 SPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQ-NEVPEVKKEETL
:::: :::::::: :: ::.::..::.:.:.:::.:::::::::::: :. ::
CCDS42 SPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 LDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSL
CCDS42 AAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHD
360 370 380 390 400 410
>>CCDS2142.1 BIN1 gene_id:274|Hs108|chr2 (518 aa)
initn: 1812 init1: 1168 opt: 1461 Z-score: 816.9 bits: 161.2 E(32554): 3.5e-39
Smith-Waterman score: 1550; 43.4% identity (61.1% similar) in 694 aa overlap (4-694:9-517)
10 20 30 40 50
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTR
. .: .:.::::.:.::::::::::::::::::::::. ::::..: .::::
CCDS21 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVD
::..:: :::..:.:.::: ::.: :.::::::: ::.... ..:. :.:: :.::::::
CCDS21 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQK
.:::.:::::::::::.:::::.:::::::::::: :.::..:.:::..:.:::::. :
CCDS21 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 AQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLG
:::::::.::::::::::::. :::::::::.....:: .::::.. : ..: .:.. :
CCDS21 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 DQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPA---SPAPARPR
::....::... :::..: . :.::::. :: .: :: :: .:. . :.
CCDS21 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPD-GSPAATPEIRVNHEPEPAGGATPGATLPK
250 260 270 280 290
300 310 320 330 340 350
pF1KB5 SPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLL
:::: :::::::: :: ::.::..::.:.:.:::.::::::::::::
CCDS21 SPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ-------------
300 310 320 330 340
360 370 380 390 400 410
pF1KB5 DLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLF
: .:::: :: ::
CCDS21 --------PTESPAGS-----------LP--------------SG---------------
350
420 430 440 450 460 470
pF1KB5 TMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGAD
::.: : ::. : . : ::
CCDS21 ---------------------EPSAAEGTFAVS--------------WPSQTAE--PG--
360 370
480 490 500 510 520 530
pF1KB5 ADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEA
:.. ::: .. :: ::. . ::.
CCDS21 ---------------PAQPAEASEV---AG----------GTQPAAGAQ-----------
380 390 400
540 550 560 570 580 590
pF1KB5 TVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQ
:: :: :: . .: : ...: :
CCDS21 -------------------------------EPGET---AASEAASSSLPAVVVETFP--
410 420
600 610 620 630 640 650
pF1KB5 DPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVV
: . :... ..: . .:::::..::.. ::. :...::: :. ::::::.
CCDS21 -------ATVNGTVEGGSGA--GRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVI
430 440 450 460 470
660 670 680 690
pF1KB5 PSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
: .. .:: :::.::::::: :...: .:.::::::.:.
CCDS21 PFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
480 490 500 510
>>CCDS42743.1 BIN1 gene_id:274|Hs108|chr2 (475 aa)
initn: 1569 init1: 1155 opt: 1246 Z-score: 700.1 bits: 139.5 E(32554): 1.1e-32
Smith-Waterman score: 1247; 39.2% identity (55.9% similar) in 691 aa overlap (4-694:9-474)
10 20 30 40 50
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTR
. .: .:.::::.:.::::::::::::::::::::::. ::::..: .::::
CCDS42 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVD
::..:: :::..:.:.::: ::.: :.::::::: ::.... ..:. :.:: :.::::::
CCDS42 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQK
.:::.:::::::::::.:::::.:::::::::::: :.::..:.:::..:.:::::. :
CCDS42 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 AQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLG
:::::::.::::::::::::. :::::::::.....:: .::::.. : ..: .:.. :
CCDS42 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 DQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPS
::....::... :::..: . :.::::. :: .: :: : :: .:.
CCDS42 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPD-GSPAATPEIRVNHE-----PEPAGGATPG
250 260 270 280 290
300 310 320 330 340 350
pF1KB5 QTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLD
: ::: .:::
CCDS42 AT--------LPK---------------------------SPSQ----------------
300
360 370 380 390 400 410
pF1KB5 FDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQ
: .:::: :: ::
CCDS42 -----PTESPAGS-----------LP--------------SG------------------
310
420 430 440 450 460 470
pF1KB5 TDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADA
::.: : ::. : . : ::
CCDS42 ------------------EPSAAEGTFAVS--------------WPSQTAE--PG-----
320 330
480 490 500 510 520 530
pF1KB5 AVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVP
:.. ::: .. :: ::. . ::.
CCDS42 ------------PAQPAEASEV---AG----------GTQPAAGAQ--------------
340 350
540 550 560 570 580 590
pF1KB5 QEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQ
:: :: :: . .: : ...: :
CCDS42 ----------------------------EPGET---AASEAASSSLPAVVVETFP-----
360 370 380
600 610 620 630 640 650
pF1KB5 PTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSD
: . :... ..: . .:::::..::.. ::. :...::: :. ::::::.: .
CCDS42 ----ATVNGTVEGGSGA--GRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQ
390 400 410 420 430
660 670 680 690
pF1KB5 SEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
. .:: :::.::::::: :...: .:.::::::.:.
CCDS42 NPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
440 450 460 470
>>CCDS46403.1 BIN1 gene_id:274|Hs108|chr2 (439 aa)
initn: 1503 init1: 1155 opt: 1235 Z-score: 694.6 bits: 138.3 E(32554): 2.3e-32
Smith-Waterman score: 1235; 56.2% identity (80.4% similar) in 336 aa overlap (4-336:9-343)
10 20 30 40 50
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTR
. .: .:.::::.:.::::::::::::::::::::::. ::::..: .::::
CCDS46 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVD
::..:: :::..:.:.::: ::.: :.::::::: ::.... ..:. :.:: :.::::::
CCDS46 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQK
.:::.:::::::::::.:::::.:::::::::::: :.::..:.:::..:.:::::. :
CCDS46 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 AQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLG
:::::::.::::::::::::. :::::::::.....:: .::::.. : ..: .:.. :
CCDS46 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 DQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPA---SPAPARPR
::....::... :::..: . :.::::. :: .: :: :: .:. . :.
CCDS46 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPD-GSPAATPEIRVNHEPEPAGGATPGATLPK
250 260 270 280 290
300 310 320 330 340 350
pF1KB5 SPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLL
:::: .. : . . . :. : .. .: . : :
CCDS46 SPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 DLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLF
CCDS46 RLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQ
360 370 380 390 400 410
>>CCDS2143.1 BIN1 gene_id:274|Hs108|chr2 (409 aa)
initn: 1506 init1: 1155 opt: 1232 Z-score: 693.5 bits: 138.0 E(32554): 2.6e-32
Smith-Waterman score: 1232; 61.6% identity (85.9% similar) in 297 aa overlap (4-297:9-304)
10 20 30 40 50
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTR
. .: .:.::::.:.::::::::::::::::::::::. ::::..: .::::
CCDS21 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVD
::..:: :::..:.:.::: ::.: :.::::::: ::.... ..:. :.:: :.::::::
CCDS21 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQK
.:::.:::::::::::.:::::.:::::::::::: :.::..:.:::..:.:::::. :
CCDS21 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 AQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLG
:::::::.::::::::::::. :::::::::.....:: .::::.. : ..: .:.. :
CCDS21 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 DQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPA---SPAPARPR
::....::... :::..: . :.::::. :: .: :: :: .:. . :.
CCDS21 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPD-GSPAATPEIRVNHEPEPAGGATPGATLPK
250 260 270 280 290
300 310 320 330 340 350
pF1KB5 SPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLL
::::.
CCDS21 SPSQSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKA
300 310 320 330 340 350
>>CCDS82508.1 BIN1 gene_id:274|Hs108|chr2 (424 aa)
initn: 1507 init1: 1105 opt: 1142 Z-score: 644.1 bits: 128.9 E(32554): 1.5e-29
Smith-Waterman score: 1192; 58.7% identity (81.7% similar) in 312 aa overlap (4-297:9-319)
10 20 30 40 50
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTR
. .: .:.::::.:.::::::::::::::::::::::. ::::..: .::::
CCDS82 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVD
::..:: :::..:.:.::: ::.: :.::::::: ::.... ..:. :.:: :.::::::
CCDS82 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQK
.:::.:::::::::::.:::::.:::::::::::: :.::..:.:::..:.:::::. :
CCDS82 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 AQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLG
:::::::.::::::::::::. :::::::::.....:: .::::.. : ..: .:.. :
CCDS82 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
190 200 210 220 230 240
240 250 260 270 280
pF1KB5 DQHADKAFTIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHT
::....::... : ::..: . :.::::. :: .: ::
CCDS82 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPD-GSPAATPEIRVNHE
250 260 270 280 290
290 300 310 320 330
pF1KB5 LAPA---SPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTP
:: .:. . :.::::.
CCDS82 PEPAGGATPGATLPKSPSQSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQ
300 310 320 330 340 350
>>CCDS2137.1 BIN1 gene_id:274|Hs108|chr2 (454 aa)
initn: 1504 init1: 1105 opt: 1141 Z-score: 643.2 bits: 128.9 E(32554): 1.7e-29
Smith-Waterman score: 1195; 53.8% identity (76.9% similar) in 351 aa overlap (4-336:9-358)
10 20 30 40 50
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTR
. .: .:.::::.:.::::::::::::::::::::::. ::::..: .::::
CCDS21 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVD
::..:: :::..:.:.::: ::.: :.::::::: ::.... ..:. :.:: :.::::::
CCDS21 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQK
.:::.:::::::::::.:::::.:::::::::::: :.::..:.:::..:.:::::. :
CCDS21 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 AQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLG
:::::::.::::::::::::. :::::::::.....:: .::::.. : ..: .:.. :
CCDS21 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
190 200 210 220 230 240
240 250 260 270 280
pF1KB5 DQHADKAFTIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHT
::....::... : ::..: . :.::::. :: .: ::
CCDS21 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPD-GSPAATPEIRVNHE
250 260 270 280 290
290 300 310 320 330
pF1KB5 LAPA---SPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTP
:: .:. . :.:::: .. : . . . :. : .. .: . : :
CCDS21 PEPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETF
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 SQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASG
CCDS21 PATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQ
360 370 380 390 400 410
>>CCDS2141.1 BIN1 gene_id:274|Hs108|chr2 (497 aa)
initn: 1789 init1: 1105 opt: 1140 Z-score: 642.1 bits: 128.8 E(32554): 1.9e-29
Smith-Waterman score: 1422; 60.7% identity (82.5% similar) in 361 aa overlap (4-345:9-368)
10 20 30 40 50
pF1KB5 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTR
. .: .:.::::.:.::::::::::::::::::::::. ::::..: .::::
CCDS21 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVD
::..:: :::..:.:.::: ::.: :.::::::: ::.... ..:. :.:: :.::::::
CCDS21 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQK
.:::.:::::::::::.:::::.:::::::::::: :.::..:.:::..:.:::::. :
CCDS21 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 AQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLG
:::::::.::::::::::::. :::::::::.....:: .::::.. : ..: .:.. :
CCDS21 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
190 200 210 220 230 240
240 250 260 270 280
pF1KB5 DQHADKAFTIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHT
::....::... : ::..: . :.::::. :: .: ::
CCDS21 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPD-GSPAATPEIRVNHE
250 260 270 280 290
290 300 310 320 330
pF1KB5 LAPA---SPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTP
:: .:. . :.:::: :::::::: :: ::.::..::.:.:.:::.::::::::::
CCDS21 PEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTP
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 SQ-NEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPAS
:: :. ::
CCDS21 SQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRL
360 370 380 390 400 410
695 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:59:33 2016 done: Mon Nov 7 15:59:34 2016
Total Scan time: 4.790 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]