Result of FASTA (omim) for
pFN21AB5755
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5755, 810 aa
1>>>pF1KB5755 810 - 810 aa - 810 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2461+/-0.000371; mu= 16.4982+/- 0.023
mean_var=109.3823+/-21.746, 0's: 0 Z-trim(116.5): 347 B-trim: 0 in 0/60
Lambda= 0.122631
statistics sampled from 27326 (27698) to 27326 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.325), width: 16
Scan time: 8.900
The best scores are: opt bits E(85289)
NP_000292 (OMIM: 173350,217090) plasminogen isofor ( 810) 5880 1051.7 0
NP_005568 (OMIM: 152200) apolipoprotein(a) precurs (2040) 2359 429.1 9.3e-119
XP_011532040 (OMIM: 142408) PREDICTED: hepatocyte ( 515) 1109 207.5 1.2e-52
XP_011532039 (OMIM: 142408) PREDICTED: hepatocyte ( 523) 1109 207.5 1.2e-52
NP_066278 (OMIM: 142408) hepatocyte growth factor- ( 725) 1109 207.6 1.6e-52
XP_016861957 (OMIM: 142408) PREDICTED: hepatocyte ( 366) 970 182.8 2.4e-45
NP_001161810 (OMIM: 173350,217090) plasminogen iso ( 136) 907 171.3 2.5e-42
XP_016867586 (OMIM: 142409,608265) PREDICTED: hepa ( 290) 811 154.6 5.8e-37
NP_001010931 (OMIM: 142409,608265) hepatocyte grow ( 290) 811 154.6 5.8e-37
XP_016867587 (OMIM: 142409,608265) PREDICTED: hepa ( 285) 777 148.6 3.7e-35
NP_001010933 (OMIM: 142409,608265) hepatocyte grow ( 285) 777 148.6 3.7e-35
NP_001010932 (OMIM: 142409,608265) hepatocyte grow ( 723) 775 148.5 9.7e-35
XP_011514417 (OMIM: 142409,608265) PREDICTED: hepa ( 723) 775 148.5 9.7e-35
XP_006716019 (OMIM: 142409,608265) PREDICTED: hepa ( 728) 775 148.5 9.7e-35
NP_000592 (OMIM: 142409,608265) hepatocyte growth ( 728) 775 148.5 9.7e-35
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 681 131.6 5.3e-30
NP_001243246 (OMIM: 605511) transmembrane protease ( 453) 681 131.7 6.9e-30
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 681 131.7 6.9e-30
XP_011520749 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 678 131.1 8.1e-30
XP_011520748 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 678 131.1 8.1e-30
NP_036599 (OMIM: 609341) tryptase gamma preproprot ( 321) 671 129.9 1.8e-29
NP_002763 (OMIM: 226200,606635) enteropeptidase pr (1019) 659 128.1 1.9e-28
XP_011527961 (OMIM: 226200,606635) PREDICTED: ente (1034) 656 127.6 2.8e-28
XP_011527960 (OMIM: 226200,606635) PREDICTED: ente (1037) 656 127.6 2.8e-28
XP_011527959 (OMIM: 226200,606635) PREDICTED: ente (1049) 656 127.6 2.8e-28
XP_011527956 (OMIM: 226200,606635) PREDICTED: ente (1064) 656 127.6 2.8e-28
XP_011527958 (OMIM: 226200,606635) PREDICTED: ente (1064) 656 127.6 2.8e-28
XP_011527957 (OMIM: 226200,606635) PREDICTED: ente (1064) 656 127.6 2.8e-28
NP_001231924 (OMIM: 610050) transmembrane protease ( 563) 646 125.6 5.9e-28
NP_001193718 (OMIM: 610050) transmembrane protease ( 532) 645 125.4 6.4e-28
NP_001070731 (OMIM: 610050) transmembrane protease ( 567) 645 125.5 6.7e-28
NP_001898 (OMIM: 118888) chymotrypsin-like proteas ( 264) 636 123.6 1.1e-27
NP_001897 (OMIM: 118890) chymotrypsinogen B isofor ( 263) 624 121.5 4.9e-27
NP_254275 (OMIM: 609443) chymotrypsin-like elastas ( 269) 620 120.8 8.2e-27
XP_011532034 (OMIM: 142408) PREDICTED: hepatocyte ( 737) 626 122.2 8.5e-27
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384) 612 119.5 2.9e-26
NP_001275930 (OMIM: 206200,609862) transmembrane p ( 802) 616 120.4 3.1e-26
NP_705837 (OMIM: 206200,609862) transmembrane prot ( 811) 616 120.4 3.1e-26
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452) 612 119.5 3.2e-26
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492) 612 119.6 3.5e-26
NP_005647 (OMIM: 602060) transmembrane protease se ( 492) 612 119.6 3.5e-26
NP_001128571 (OMIM: 602060) transmembrane protease ( 529) 612 119.6 3.7e-26
NP_001027564 (OMIM: 173340) plasminogen-like prote ( 96) 600 116.9 4.3e-26
XP_011526284 (OMIM: 610477) PREDICTED: transmembra ( 562) 608 118.9 6.2e-26
XP_011526282 (OMIM: 610477) PREDICTED: transmembra ( 690) 608 119.0 7.3e-26
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436) 605 118.3 7.4e-26
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436) 605 118.3 7.4e-26
NP_001182058 (OMIM: 613517,613858) serine protease ( 603) 606 118.6 8.4e-26
NP_000883 (OMIM: 229000,612423) plasma kallikrein ( 638) 605 118.4 9.9e-26
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649) 605 118.4 1e-25
>>NP_000292 (OMIM: 173350,217090) plasminogen isoform 1 (810 aa)
initn: 5880 init1: 5880 opt: 5880 Z-score: 5625.2 bits: 1051.7 E(85289): 0
Smith-Waterman score: 5880; 99.9% identity (99.9% similar) in 810 aa overlap (1-810:1-810)
10 20 30 40 50 60
pF1KB5 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 CEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 AQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 QLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 LTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEED
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 CMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 PWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 RFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 PTRKDIALLKLSSPADITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQ
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_000 PTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 LPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSW
730 740 750 760 770 780
790 800 810
pF1KB5 GLGCARPNKPGVYVRVSRFVTWIEGVMRNN
::::::::::::::::::::::::::::::
NP_000 GLGCARPNKPGVYVRVSRFVTWIEGVMRNN
790 800 810
>>NP_005568 (OMIM: 152200) apolipoprotein(a) precursor [ (2040 aa)
initn: 2309 init1: 2287 opt: 2359 Z-score: 2253.0 bits: 429.1 E(85289): 9.3e-119
Smith-Waterman score: 3626; 63.9% identity (78.0% similar) in 785 aa overlap (95-810:1266-2040)
70 80 90 100 110 120
pF1KB5 QYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGITC
:.. ...: :.:..:::..: : .: ::
NP_005 RWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTTVTGRTC
1240 1250 1260 1270 1280 1290
130 140 150 160 170 180
pF1KB5 QKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILEC---
:.::: .:: . . .:. :: .::::::: . . ::::: :: :..::.. .:
NP_005 QSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIR-PWCYTMDPSVRWEYCNLTQCPVM
1300 1310 1320 1330 1340 1350
190 200 210
pF1KB5 --------------------EE----------ECMHCSGENYDGKISKTMSGLECQAWDS
:: .:.. .:..: : .: :..: ::.:.:
NP_005 ESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSS
1360 1370 1380 1390 1400 1410
220 230 240 250 260
pF1KB5 QSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRC--------T
..:: : :: .:: .: .::::::: :.::::.: ::. ::: :.. :: :
NP_005 MTPHWHRRIPLYYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTRCPVTESSVLT
1420 1430 1440 1450 1460 1470
270 280 290 300
pF1KB5 TP---------------PPSSGPTYQ-CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTH
:: :: ..:. : : .: :..::: ..::.:.::: ::.. :: :
NP_005 TPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWH
1480 1490 1500 1510 1520 1530
310 320 330 340 350
pF1KB5 NRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSS-----------P
.:::::.: .: ::::::::. . :::.::. ::::::.. .:. . :
NP_005 QRTPENYPNAGLTENYCRNPDSGKQPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVP
1540 1550 1560 1570 1580 1590
360 370 380 390 400 410
pF1KB5 V-STEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPEN
: : : . .:: : ::::..::::.::::::: :::.::. :::::::::::::.::::
NP_005 VPSMEAHSEAAPTEQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPEN
1600 1610 1620 1630 1640 1650
420 430 440 450 460 470
pF1KB5 YPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVET
::: ::::::::::::: :::::: :::.::::::: .:: ::..::::: :. .:..
NP_005 YPNDGLTMNYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGP
1660 1670 1680 1690 1700 1710
480 490 500 510 520 530
pF1KB5 PSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPD
:::.:::::::::::::.::::::::::.:::::::::: : : :: ::::::::::::
NP_005 PSEQDCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPD
1720 1730 1740 1750 1760 1770
540 550 560 570 580 590
pF1KB5 GDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQ
::..:::::: :::::.::::.: ::. :::::::::::::::: .::::::::::::::
NP_005 GDINGPWCYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQ
1780 1790 1800 1810 1820 1830
600 610 620 630 640 650
pF1KB5 VSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVS
:::::::: ::::::::::::::::::::.:: :::::::::::::::::: ::::::::
NP_005 VSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVS
1840 1850 1860 1870 1880 1890
660 670 680 690 700 710
pF1KB5 RLFLEPTRKDIALLKLSSPADITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGL
:::::::. :::::::: :: :::::.:::::::.:.:. ::::.::::::::::::.::
NP_005 RLFLEPTQADIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGL
1900 1910 1920 1930 1940 1950
720 730 740 750 760 770
pF1KB5 LKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQ
:::::: ::::.:::.:... :: ::: ::::::::::::::::::::::::
NP_005 LKEAQLLVIENEVCNHYKYI---------CAEHLARGTDSCQGDSGGPLVCFEKDKYILQ
1960 1970 1980 1990 2000
780 790 800 810
pF1KB5 GVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
::::::::::::::::::.:::::::::::.::::
NP_005 GVTSWGLGCARPNKPGVYARVSRFVTWIEGMMRNN
2010 2020 2030 2040
>--
initn: 600 init1: 600 opt: 898 Z-score: 856.1 bits: 170.6 E(85289): 6e-41
Smith-Waterman score: 1493; 48.3% identity (69.2% similar) in 439 aa overlap (183-574:26-462)
160 170 180 190 200 210
pF1KB5 RNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQ
..:.: .:..: : : :..: ::::.:.
NP_005 MEHKEVVLLLLLFLKSAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSM
10 20 30 40 50
220 230 240 250 260
pF1KB5 SPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCT---------
.:: :. ..:: .: ::::::: :.:.: ::. ::: :.. .:.
NP_005 TPHQHNRTTENYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAP
60 70 80 90 100 110
270 280 290 300
pF1KB5 ---TPPPS------SGPTYQ------CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHN
:: :: ..:: : : .:.:..:::. ..::.:.::: ::..:::.:.
NP_005 PTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHS
120 130 140 150 160 170
310 320 330 340 350
pF1KB5 RTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDS-----------SPV
:::: .: .: :::::::. ::.:.: . ::::::.. .:.. .::
NP_005 RTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPV
180 190 200 210 220 230
360 370 380 390 400 410
pF1KB5 -STEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENY
: : . :: : : ::.::::.::::::: :::.::. ::.::::::: :..::: :
NP_005 PSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYY
240 250 260 270 280 290
420 430 440 450 460 470
pF1KB5 PNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETP
::::: ::::::::: .:.:.: ::.:::::::: .:: .:...:::: :. .:..:.:
NP_005 PNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAP
300 310 320 330 340 350
480 490 500 510 520
pF1KB5 SEE----------DCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGL
::. .:. :::..::: .::::: :: :... :: :: ::: : :::
NP_005 SEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHS-RTPEYYPNAGL
360 370 380 390 400 410
530 540 550 560 570 580
pF1KB5 EKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCA-APSFDCGKPQVEPKKCPGRVVGGC
:::::::. :..:.::: .: ..::.. ::. : . . : : :
NP_005 IMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA
420 430 440 450 460 470
590 600 610 620 630 640
pF1KB5 VAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNL
NP_005 PTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYC
480 490 500 510 520 530
>--
initn: 586 init1: 586 opt: 888 Z-score: 846.5 bits: 168.9 E(85289): 2.1e-40
Smith-Waterman score: 1509; 48.5% identity (69.2% similar) in 439 aa overlap (183-574:482-918)
160 170 180 190 200 210
pF1KB5 RNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQ
.::.: .:..: : : :..: ::::.:.
NP_005 GTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSM
460 470 480 490 500 510
220 230 240 250 260
pF1KB5 SPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCT---------
.::.:. : .:: .: ::::::: :.:.: ::. ::: :.. .:.
NP_005 TPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAP
520 530 540 550 560 570
270 280 290 300
pF1KB5 ---TPPPS------SGPTYQ------CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHN
:: :: ..:: : : .:.:..:::. ..::.:.::: ::..:::.:.
NP_005 PTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHS
580 590 600 610 620 630
310 320 330 340 350
pF1KB5 RTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDS-----------SPV
:::: .: .: :::::::. ::.:.: . ::::::.. .:.. .::
NP_005 RTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPV
640 650 660 670 680 690
360 370 380 390 400 410
pF1KB5 -STEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENY
: : . :: : : ::.::::.::::::: :::.::. ::.::::::: :..::: :
NP_005 PSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYY
700 710 720 730 740 750
420 430 440 450 460 470
pF1KB5 PNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETP
::::: ::::::::: .:.:.: ::.:::::::: .:: .:...:::: :. .:..:.:
NP_005 PNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAP
760 770 780 790 800 810
480 490 500 510 520
pF1KB5 SEE----------DCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGL
::. .:. :::..::: .::::: :: :... :: :: ::: : :::
NP_005 SEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHS-RTPEYYPNAGL
820 830 840 850 860 870
530 540 550 560 570 580
pF1KB5 EKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCA-APSFDCGKPQVEPKKCPGRVVGGC
::::::: :..:.::: .: ..::.. ::. : . . : . :
NP_005 IMNYCRNPD-PVAAPYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQA
880 890 900 910 920
590 600 610 620 630 640
pF1KB5 VAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNL
NP_005 PTEQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYC
930 940 950 960 970 980
>--
initn: 558 init1: 558 opt: 884 Z-score: 842.7 bits: 168.2 E(85289): 3.4e-40
Smith-Waterman score: 1196; 51.2% identity (70.5% similar) in 322 aa overlap (183-468:938-1259)
160 170 180 190 200 210
pF1KB5 RNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQ
.::.: .:..:.: :..: ::::.:.
NP_005 GTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSM
910 920 930 940 950 960
220 230 240 250 260
pF1KB5 SPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCT-------TP
.::.:. :. .:: .: :::::::: :::.::::. ::: :.. ::. .:
NP_005 TPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVP
970 980 990 1000 1010 1020
270 280 290 300
pF1KB5 P-----PS-----------SGPTYQ-CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHN
: :: : : : :..:::. ..::.:.::: ::..::: :.
NP_005 PNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHS
1030 1040 1050 1060 1070 1080
310 320 330 340 350 360
pF1KB5 RTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSC---DSSPVSTEQLAPT
:::::.: .: .:::::::.. :::.: . .::::::.. .: .:: ..: ..:
NP_005 RTPENYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPD
1090 1100 1110 1120 1130 1140
370 380 390 400 410
pF1KB5 ---------APPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENY
:: : .: ::::::::::::::. :::.::. :::::::::: ::.: : :
NP_005 PSTEASSEEAPTEQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYY
1150 1160 1170 1180 1190 1200
420 430 440 450 460 470
pF1KB5 PNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETP
::.::: ::::::::. .:::.: ::.:::::::: .: ::.::.: .:
NP_005 PNGGLTRNYCRNPDAEISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQ
1210 1220 1230 1240 1250 1260
480 490 500 510 520 530
pF1KB5 SEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDG
NP_005 SPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPD
1270 1280 1290 1300 1310 1320
>>XP_011532040 (OMIM: 142408) PREDICTED: hepatocyte grow (515 aa)
initn: 1128 init1: 364 opt: 1109 Z-score: 1066.1 bits: 207.5 E(85289): 1.2e-52
Smith-Waterman score: 1439; 43.2% identity (65.3% similar) in 475 aa overlap (9-466:20-474)
10 20 30
pF1KB5 MEHKEVVLLLLLFLKS----GQGEPLDDYVNTQGASLFSVTKK------
::::. . :: ::.:. .:. : . .
XP_011 MGLWWVTVQPPARRMGWLPLLLLLTQCLGVPGQRSPLNDFQVLRGTELQHLLHAVVPGPW
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 QLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKS--SIIIRMRDVVLFEKK
: ... ::::..: . ::::.:. . . : .. ...: . . : ::.::
XP_011 QEDVADAEECAGRC--GPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLFQKK
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 VYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDN
:. : .:: .:::::. : .:. :: :: :. ...:. . .:::::.:::::.
XP_011 DYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLR--NGLEENFCRNPDG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 DPQGPWCYTTDPEKRYDYCDILECEEE-CMHCSGENYDGKISKTMSGLECQAWDSQSPHA
:: ::::::::: :.. : : :.: :. :.::.: : ...: :: ::: :: : ::
XP_011 DPGGPWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQ
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 HGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTP--PPSSGPTYQ
: . :.:: ...: ::::::: ::::.::::. . :.::.::: . : . . : .
XP_011 HPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVS
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPW
:..: ::.:::.. .:..: ::.:.:: :: : :::.. ::.: ::.::::::..:::
XP_011 CFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPW
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 CHTTNSQVRWEYC-KIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTT
: : .: .: .: : :... : :::::: :..:::: : :
XP_011 CFTLRPGMRAAFCYQIRRC------TDDVRP----------QDCYHGAGEQYRGTVSKTR
360 370 380 390 400
400 410 420 430 440 450
pF1KB5 TGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADK-GPWCFTTDPSVRWEYCNLK
: .:: ::. :::. : : . :.: : :.:::::.:. ::::.: :: . ..:: :.
XP_011 KGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALR
410 420 430 440 450 460
460 470 480 490 500 510
pF1KB5 KCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHR
.:. . . ::
XP_011 RCADDQPPSILDPPDQVQFEKCGKRVDRLDQRRSKLRVVGGHPGNSPWTVSLRNR
470 480 490 500 510
>>XP_011532039 (OMIM: 142408) PREDICTED: hepatocyte grow (523 aa)
initn: 1330 init1: 364 opt: 1109 Z-score: 1066.0 bits: 207.5 E(85289): 1.2e-52
Smith-Waterman score: 1444; 41.1% identity (63.6% similar) in 525 aa overlap (9-515:20-518)
10 20 30
pF1KB5 MEHKEVVLLLLLFLKS----GQGEPLDDYVNTQGASLFSVTKK------
::::. . :: ::.:. .:. : . .
XP_011 MGLWWVTVQPPARRMGWLPLLLLLTQCLGVPGQRSPLNDFQVLRGTELQHLLHAVVPGPW
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 QLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKS--SIIIRMRDVVLFEKK
: ... ::::..: . ::::.:. . . : .. ...: . . : ::.::
XP_011 QEDVADAEECAGRC--GPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLFQKK
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 VYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDN
:. : .:: .:::::. : .:. :: :: :. ...:. . .:::::.:::::.
XP_011 DYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLR--NGLEENFCRNPDG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 DPQGPWCYTTDPEKRYDYCDILECEEE-CMHCSGENYDGKISKTMSGLECQAWDSQSPHA
:: ::::::::: :.. : : :.: :. :.::.: : ...: :: ::: :: : ::
XP_011 DPGGPWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQ
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 HGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTP--PPSSGPTYQ
: . :.:: ...: ::::::: ::::.::::. . :.::.::: . : . . : .
XP_011 HPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVS
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPW
:..: ::.:::.. .:..: ::.:.:: :: : :::.. ::.: ::.::::::..:::
XP_011 CFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPW
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 CHTTNSQVRWEYC-KIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTT
: : .: .: .: : :... : :::::: :..:::: : :
XP_011 CFTLRPGMRAAFCYQIRRC------TDDVRP----------QDCYHGAGEQYRGTVSKTR
360 370 380 390 400
400 410 420 430 440 450
pF1KB5 TGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADK-GPWCFTTDPSVRWEYCNLK
: .:: ::. :::. : : . :.: : :.:::::.:. ::::.: :: . ..:: :.
XP_011 KGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALR
410 420 430 440 450 460
460 470 480 490 500 510
pF1KB5 KCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQD-WAAQEPH
.:. . :: .: : .. :. . : .. .: : : .. :... .
XP_011 RCADDQ------PPSILDPPDQVQFEKCGKRVDRLDQRRSKLRVVGGHPGNSPWTVSLRN
470 480 490 500 510
520 530 540 550 560 570
pF1KB5 RHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQ
: ::
XP_011 RASISAGGL
520
>>NP_066278 (OMIM: 142408) hepatocyte growth factor-like (725 aa)
initn: 1330 init1: 364 opt: 1109 Z-score: 1064.0 bits: 207.6 E(85289): 1.6e-52
Smith-Waterman score: 1885; 38.2% identity (59.4% similar) in 820 aa overlap (9-808:20-723)
10 20 30
pF1KB5 MEHKEVVLLLLLFLKS----GQGEPLDDYVNTQGASLFSVTKK------
::::. . :: ::.:. .:. : . .
NP_066 MGLWWVTVQPPARRMGWLPLLLLLTQCLGVPGQRSPLNDFQVLRGTELQHLLHAVVPGPW
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 QLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKS--SIIIRMRDVVLFEKK
: ... ::::..: . ::::.:. . . : .. ...: . . : ::.::
NP_066 QEDVADAEECAGRC--GPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLFQKK
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 VYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDN
:. : .:: .:::::. : .:. :: :: :. ...:. . .:::::.:::::.
NP_066 DYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLR--NGLEENFCRNPDG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 DPQGPWCYTTDPEKRYDYCDILECEEE-CMHCSGENYDGKISKTMSGLECQAWDSQSPHA
:: ::::::::: :.. : : :.: :. :.::.: : ...: :: ::: :: : ::
NP_066 DPGGPWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQ
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 HGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTP--PPSSGPTYQ
: . :.:: ...: ::::::: ::::.::::. . :.::.::: . : . . : .
NP_066 HPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVS
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPW
:..: ::.:::.. .:..: ::.:.:: :: : :::.. ::.: ::.::::::..:::
NP_066 CFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPW
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 CHTTNSQVRWEYC-KIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTT
: : .: .: .: : :... : :::::: :..:::: : :
NP_066 CFTLRPGMRAAFCYQIRRC------TDDVRP----------QDCYHGAGEQYRGTVSKTR
360 370 380 390 400
400 410 420 430 440 450
pF1KB5 TGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADK-GPWCFTTDPSVRWEYCNLK
: .:: ::. :::. : : . :.: : :.:::::.:. ::::.: :: . ..:: :.
NP_066 KGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALR
410 420 430 440 450 460
460 470 480 490 500 510
pF1KB5 KCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHR
.:. . :: .: : .. :. : :::. . .:
NP_066 RCADDQ------PPSILDPPDQVQFEK-C---------GKRVDRLD------------QR
470 480 490
520 530 540 550 560 570
pF1KB5 HSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQV
.: ::
NP_066 RS-----------------------------------KL---------------------
580 590 600 610 620 630
pF1KB5 EPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRP-S
::::: :: . :: ::::.: :.:::::.:.. .:.::: .:. . : .
NP_066 -------RVVGG---HPGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLT
500 510 520 530 540
640 650 660 670 680
pF1KB5 SYKVILGA--HQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPADITDKVIPACLPSP
.:.: ::. .. . :: .:.. :... :. ....:::: . ....: :::
NP_066 GYEVWLGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQLVLLKLERSVTLNQRVALICLPPE
550 560 570 580 590 600
690 700 710 720 730 740
pF1KB5 NYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHL
::: :.: :.:::::.:: . .:. : : :: :. :: . :::. .:.:. :
NP_066 WYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKH--RGRVRESEMCTEGL
610 620 630 640 650 660
750 760 770 780 790 800
pF1KB5 AGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRN
. . .:.:: ::::.:: .. ..:.:. . ::: :.:..::: :: ::. :::
NP_066 LAPVGACEGDYGGPLACFTHNCWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVMRL
670 680 690 700 710 720
810
pF1KB5 N
NP_066 G
>>XP_016861957 (OMIM: 142408) PREDICTED: hepatocyte grow (366 aa)
initn: 931 init1: 364 opt: 970 Z-score: 935.2 bits: 182.8 E(85289): 2.4e-45
Smith-Waterman score: 971; 41.3% identity (64.4% similar) in 351 aa overlap (9-343:20-366)
10 20 30
pF1KB5 MEHKEVVLLLLLFLKS----GQGEPLDDYVNTQGASLFSVTKK------
::::. . :: ::.:. .:. : . .
XP_016 MGLWWVTVQPPARRMGWLPLLLLLTQCLGVPGQRSPLNDFQVLRGTELQHLLHAVVPGPW
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 QLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKS--SIIIRMRDVVLFEKK
: ... ::::..: . ::::.:. . . : .. ...: . . : ::.::
XP_016 QEDVADAEECAGRC--GPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLFQKK
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 VYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDN
:. : .:: .:::::. : .:. :: :: :. ...:. . .:::::.:::::.
XP_016 DYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLR--NGLEENFCRNPDG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 DPQGPWCYTTDPEKRYDYCDILECEEE-CMHCSGENYDGKISKTMSGLECQAWDSQSPHA
:: ::::::::: :.. : : :.: :. :.::.: : ...: :: ::: :: : ::
XP_016 DPGGPWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQ
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 HGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTP--PPSSGPTYQ
: . :.:: ...: ::::::: ::::.::::. . :.::.::: . : . . : .
XP_016 HPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVS
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNP-DGKRAP
:..: ::.:::.. .:..: ::.:.:: :: : :::.. :: : . : :.. :
XP_016 CFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKLLPRRRGAVPRHGQQDP
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 WCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTT
. . ::
XP_016 QGCPVPALVR
360
>>NP_001161810 (OMIM: 173350,217090) plasminogen isoform (136 aa)
initn: 907 init1: 907 opt: 907 Z-score: 880.9 bits: 171.3 E(85289): 2.5e-42
Smith-Waterman score: 907; 100.0% identity (100.0% similar) in 136 aa overlap (1-136:1-136)
10 20 30 40 50 60
pF1KB5 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILE
::::::::::::::::
NP_001 GITCQKWSSTSPHRPR
130
>>XP_016867586 (OMIM: 142409,608265) PREDICTED: hepatocy (290 aa)
initn: 855 init1: 373 opt: 811 Z-score: 784.6 bits: 154.6 E(85289): 5.8e-37
Smith-Waterman score: 811; 45.1% identity (70.8% similar) in 233 aa overlap (37-264:61-290)
10 20 30 40 50 60
pF1KB5 VLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDE--EFTCRAF
::: ... ..:: .: ... :::.::
XP_016 GQRKRRNTIHEFKKSAKTTLIKIDPALKIKTKK---VNTADQCANRCTRNKGLPFTCKAF
40 50 60 70 80
70 80 90 100 110 120
pF1KB5 QYHSKEQQCVIMAENRKSSIIIRM--RDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGI
. . ..::. . : :: . . .. :.:.: :. .: :.:..:.::.: ::.::
XP_016 VFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGI
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB5 TCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECE
:: ::: ::. : :... .. :.::::::: .. ::::.:..:: ::. ::: .:
XP_016 KCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCS
150 160 170 180 190 200
190 200 210 220 230 240
pF1KB5 E-ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL
: ::: :.::.: : ...: :: :: :: :.:: : ..: ..:.:.. ::::::: .
XP_016 EVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP
210 220 230 240 250 260
250 260 270 280 290 300
pF1KB5 RPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSA
::::.: ::. ::: : : : :
XP_016 RPWCYTLDPHTRWEYCAIKTCET
270 280 290
>>NP_001010931 (OMIM: 142409,608265) hepatocyte growth f (290 aa)
initn: 855 init1: 373 opt: 811 Z-score: 784.6 bits: 154.6 E(85289): 5.8e-37
Smith-Waterman score: 811; 45.1% identity (70.8% similar) in 233 aa overlap (37-264:61-290)
10 20 30 40 50 60
pF1KB5 VLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDE--EFTCRAF
::: ... ..:: .: ... :::.::
NP_001 GQRKRRNTIHEFKKSAKTTLIKIDPALKIKTKK---VNTADQCANRCTRNKGLPFTCKAF
40 50 60 70 80
70 80 90 100 110 120
pF1KB5 QYHSKEQQCVIMAENRKSSIIIRM--RDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGI
. . ..::. . : :: . . .. :.:.: :. .: :.:..:.::.: ::.::
NP_001 VFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGI
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB5 TCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECE
:: ::: ::. : :... .. :.::::::: .. ::::.:..:: ::. ::: .:
NP_001 KCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCS
150 160 170 180 190 200
190 200 210 220 230 240
pF1KB5 E-ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL
: ::: :.::.: : ...: :: :: :: :.:: : ..: ..:.:.. ::::::: .
NP_001 EVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP
210 220 230 240 250 260
250 260 270 280 290 300
pF1KB5 RPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSA
::::.: ::. ::: : : : :
NP_001 RPWCYTLDPHTRWEYCAIKTCET
270 280 290
>>XP_016867587 (OMIM: 142409,608265) PREDICTED: hepatocy (285 aa)
initn: 1190 init1: 373 opt: 777 Z-score: 752.2 bits: 148.6 E(85289): 3.7e-35
Smith-Waterman score: 777; 44.2% identity (69.1% similar) in 233 aa overlap (37-264:61-285)
10 20 30 40 50 60
pF1KB5 VLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDE--EFTCRAF
::: ... ..:: .: ... :::.::
XP_016 GQRKRRNTIHEFKKSAKTTLIKIDPALKIKTKK---VNTADQCANRCTRNKGLPFTCKAF
40 50 60 70 80
70 80 90 100 110 120
pF1KB5 QYHSKEQQCVIMAENRKSSIIIRM--RDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGI
. . ..::. . : :: . . .. :.:.: :. .: :.:..:.::.: ::.::
XP_016 VFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGI
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB5 TCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECE
:: ::: ::. . .. :.::::::: .. ::::.:..:: ::. ::: .:
XP_016 KCQPWSSMIPHEHSYR-----GKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCS
150 160 170 180 190 200
190 200 210 220 230 240
pF1KB5 E-ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL
: ::: :.::.: : ...: :: :: :: :.:: : ..: ..:.:.. ::::::: .
XP_016 EVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP
210 220 230 240 250 260
250 260 270 280 290 300
pF1KB5 RPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSA
::::.: ::. ::: : : : :
XP_016 RPWCYTLDPHTRWEYCAIKTCET
270 280
810 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:14:40 2016 done: Tue Nov 8 17:14:42 2016
Total Scan time: 8.900 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]