Result of FASTA (omim) for
pFN21AB5728
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5728, 731 aa
1>>>pF1KB5728 731 - 731 aa - 731 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5364+/-0.000397; mu= 13.9553+/- 0.025
mean_var=281.4330+/-60.681, 0's: 0 Z-trim(120.4): 142 B-trim: 2082 in 1/58
Lambda= 0.076452
statistics sampled from 35414 (35580) to 35414 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.417), width: 16
Scan time: 13.970
The best scores are: opt bits E(85289)
NP_071902 (OMIM: 608067) E3 ubiquitin-protein liga ( 731) 4864 550.6 8.3e-156
XP_005245504 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 727) 4826 546.4 1.5e-154
XP_016857550 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 757) 4752 538.3 4.4e-152
XP_016857552 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 753) 4714 534.1 8e-151
XP_016857551 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 755) 4436 503.4 1.4e-141
XP_016857553 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 752) 4298 488.2 5.2e-137
XP_016857565 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 491) 3246 371.9 3.5e-102
NP_001273573 (OMIM: 608067) E3 ubiquitin-protein l ( 491) 3165 362.9 1.7e-99
XP_006711550 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 708) 3059 351.5 6.9e-96
XP_005245505 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 711) 2960 340.6 1.3e-92
NP_001001740 (OMIM: 608067) E3 ubiquitin-protein l ( 707) 2955 340.0 2e-92
XP_016857555 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 734) 2947 339.1 3.7e-92
XP_016857554 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 737) 2848 328.2 7.2e-89
XP_016857556 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 733) 2843 327.7 1e-88
XP_016857564 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 497) 2811 323.9 9.7e-88
XP_011508183 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 749) 2770 319.6 2.8e-86
XP_016857563 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 507) 2737 315.8 2.8e-85
XP_016857562 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 515) 2737 315.8 2.8e-85
XP_016857549 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 771) 2690 310.8 1.3e-83
XP_016857548 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 775) 2658 307.3 1.5e-82
XP_016857557 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 732) 2638 305.1 6.7e-82
XP_016857561 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 527) 2627 303.6 1.3e-81
XP_016857559 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 535) 2627 303.7 1.3e-81
XP_016857560 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 535) 2627 303.7 1.3e-81
XP_016857568 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 455) 2624 303.2 1.5e-81
XP_016857567 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 455) 2624 303.2 1.5e-81
XP_016857569 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 455) 2624 303.2 1.5e-81
XP_016857558 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 613) 2624 303.4 1.8e-81
XP_016857566 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 477) 2619 302.7 2.2e-81
NP_008882 (OMIM: 601787) transcription initiation ( 800) 289 46.0 0.00069
NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 272 43.7 0.0016
>>NP_071902 (OMIM: 608067) E3 ubiquitin-protein ligase R (731 aa)
initn: 4864 init1: 4864 opt: 4864 Z-score: 2918.3 bits: 550.6 E(85289): 8.3e-156
Smith-Waterman score: 4864; 100.0% identity (100.0% similar) in 731 aa overlap (1-731:1-731)
10 20 30 40 50 60
pF1KB5 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
670 680 690 700 710 720
730
pF1KB5 SQGTIKVLELV
:::::::::::
NP_071 SQGTIKVLELV
730
>>XP_005245504 (OMIM: 608067) PREDICTED: E3 ubiquitin-pr (727 aa)
initn: 3440 init1: 3440 opt: 4826 Z-score: 2895.6 bits: 546.4 E(85289): 1.5e-154
Smith-Waterman score: 4826; 99.5% identity (99.5% similar) in 731 aa overlap (1-731:1-727)
10 20 30 40 50 60
pF1KB5 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
:::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_005 DHLYPNFLVNELILKQKQRFEEKRFKLDHS----NGHRWQIFQDWLGTDQDNLDLANVNL
190 200 210 220 230
250 260 270 280 290 300
pF1KB5 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB5 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB5 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB5 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB5 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB5 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB5 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
660 670 680 690 700 710
730
pF1KB5 SQGTIKVLELV
:::::::::::
XP_005 SQGTIKVLELV
720
>>XP_016857550 (OMIM: 608067) PREDICTED: E3 ubiquitin-pr (757 aa)
initn: 4752 init1: 4752 opt: 4752 Z-score: 2851.3 bits: 538.3 E(85289): 4.4e-152
Smith-Waterman score: 4752; 100.0% identity (100.0% similar) in 711 aa overlap (1-711:1-711)
10 20 30 40 50 60
pF1KB5 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGYPRIAWEKQ
670 680 690 700 710 720
730
pF1KB5 SQGTIKVLELV
XP_016 RSHLCHIQSWSHRWKFRSAKVFPTVAAANLFFLYRSD
730 740 750
>>XP_016857552 (OMIM: 608067) PREDICTED: E3 ubiquitin-pr (753 aa)
initn: 3328 init1: 3328 opt: 4714 Z-score: 2828.7 bits: 534.1 E(85289): 8e-151
Smith-Waterman score: 4714; 99.4% identity (99.4% similar) in 711 aa overlap (1-711:1-707)
10 20 30 40 50 60
pF1KB5 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
:::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_016 DHLYPNFLVNELILKQKQRFEEKRFKLDHS----NGHRWQIFQDWLGTDQDNLDLANVNL
190 200 210 220 230
250 260 270 280 290 300
pF1KB5 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB5 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB5 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB5 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB5 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB5 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB5 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGYPRIAWEKQ
660 670 680 690 700 710
730
pF1KB5 SQGTIKVLELV
XP_016 RSHLCHIQSWSHRWKFRSAKVFPTVAAANLFFLYRSD
720 730 740 750
>>XP_016857551 (OMIM: 608067) PREDICTED: E3 ubiquitin-pr (755 aa)
initn: 4454 init1: 2619 opt: 4436 Z-score: 2663.0 bits: 503.4 E(85289): 1.4e-141
Smith-Waterman score: 4538; 94.8% identity (94.8% similar) in 729 aa overlap (1-711:1-709)
10 20 30 40 50 60
pF1KB5 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
::::::::::::::::::::::::::::::::::::: :::
XP_016 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKRE--------------------EMS
250 260 270 280
310 320 330 340
pF1KB5 GLYSPVSEDSTVPQFEAPSPSHS------------------SIIDSTEYSQPPGFSGSSQ
::::::::::::::::::::::: :::::::::::::::::::
XP_016 GLYSPVSEDSTVPQFEAPSPSHSLEFSSDMHRIFVNGILIISIIDSTEYSQPPGFSGSSQ
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB5 TKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRY
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB5 NSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHY
410 420 430 440 450 460
470 480 490 500 510 520
pF1KB5 PENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFN
470 480 490 500 510 520
530 540 550 560 570 580
pF1KB5 LMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHY
530 540 550 560 570 580
590 600 610 620 630 640
pF1KB5 YDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINE
590 600 610 620 630 640
650 660 670 680 690 700
pF1KB5 KNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSA
650 660 670 680 690 700
710 720 730
pF1KB5 VCWRALPDGESNVLIAANSQGTIKVLELV
:::::::::
XP_016 VCWRALPDGYPRIAWEKQRSHLCHIQSWSHRWKFRSAKVFPTVAAANLFFLYRSD
710 720 730 740 750
>>XP_016857553 (OMIM: 608067) PREDICTED: E3 ubiquitin-pr (752 aa)
initn: 4416 init1: 2619 opt: 4298 Z-score: 2580.7 bits: 488.2 E(85289): 5.2e-137
Smith-Waterman score: 4508; 94.4% identity (94.4% similar) in 729 aa overlap (1-711:1-706)
10 20 30 40 50 60
pF1KB5 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
:::::::::::::: :::::::::::::::::::::::
XP_016 MLELLVQKKKQLEA-----------------------QLEQIQKELSVLEEDIKRVEEMS
250 260 270
310 320 330 340
pF1KB5 GLYSPVSEDSTVPQFEAPSPSHS------------------SIIDSTEYSQPPGFSGSSQ
::::::::::::::::::::::: :::::::::::::::::::
XP_016 GLYSPVSEDSTVPQFEAPSPSHSLEFSSDMHRIFVNGILIISIIDSTEYSQPPGFSGSSQ
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB5 TKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRY
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB5 NSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHY
400 410 420 430 440 450
470 480 490 500 510 520
pF1KB5 PENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFN
460 470 480 490 500 510
530 540 550 560 570 580
pF1KB5 LMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHY
520 530 540 550 560 570
590 600 610 620 630 640
pF1KB5 YDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINE
580 590 600 610 620 630
650 660 670 680 690 700
pF1KB5 KNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSA
640 650 660 670 680 690
710 720 730
pF1KB5 VCWRALPDGESNVLIAANSQGTIKVLELV
:::::::::
XP_016 VCWRALPDGYPRIAWEKQRSHLCHIQSWSHRWKFRSAKVFPTVAAANLFFLYRSD
700 710 720 730 740 750
>>XP_016857565 (OMIM: 608067) PREDICTED: E3 ubiquitin-pr (491 aa)
initn: 3246 init1: 3246 opt: 3246 Z-score: 1955.6 bits: 371.9 E(85289): 3.5e-102
Smith-Waterman score: 3246; 100.0% identity (100.0% similar) in 491 aa overlap (241-731:1-491)
220 230 240 250 260 270
pF1KB5 VSSTNGHRWQIFQDWLGTDQDNLDLANVNLMLELLVQKKKQLEAESHAAQLQILMEFLKV
::::::::::::::::::::::::::::::
XP_016 MLELLVQKKKQLEAESHAAQLQILMEFLKV
10 20 30
280 290 300 310 320 330
pF1KB5 ARRNKREQLEQIQKELSVLEEDIKRVEEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARRNKREQLEQIQKELSVLEEDIKRVEEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTE
40 50 60 70 80 90
340 350 360 370 380 390
pF1KB5 YSQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLD
100 110 120 130 140 150
400 410 420 430 440 450
pF1KB5 EFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEY
160 170 180 190 200 210
460 470 480 490 500 510
pF1KB5 DTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQ
220 230 240 250 260 270
520 530 540 550 560 570
pF1KB5 EHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYH
280 290 300 310 320 330
580 590 600 610 620 630
pF1KB5 LAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKP
340 350 360 370 380 390
640 650 660 670 680 690
pF1KB5 YCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKD
400 410 420 430 440 450
700 710 720 730
pF1KB5 RKEDDTNEFVSAVCWRALPDGESNVLIAANSQGTIKVLELV
:::::::::::::::::::::::::::::::::::::::::
XP_016 RKEDDTNEFVSAVCWRALPDGESNVLIAANSQGTIKVLELV
460 470 480 490
>>NP_001273573 (OMIM: 608067) E3 ubiquitin-protein ligas (491 aa)
initn: 3165 init1: 3165 opt: 3165 Z-score: 1907.3 bits: 362.9 E(85289): 1.7e-99
Smith-Waterman score: 3165; 100.0% identity (100.0% similar) in 477 aa overlap (255-731:15-491)
230 240 250 260 270 280
pF1KB5 WLGTDQDNLDLANVNLMLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQK
::::::::::::::::::::::::::::::
NP_001 MLWTILTICILISWESHAAQLQILMEFLKVARRNKREQLEQIQK
10 20 30 40
290 300 310 320 330 340
pF1KB5 ELSVLEEDIKRVEEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSVLEEDIKRVEEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTK
50 60 70 80 90 100
350 360 370 380 390 400
pF1KB5 KQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNS
110 120 130 140 150 160
410 420 430 440 450 460
pF1KB5 VRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPE
170 180 190 200 210 220
470 480 490 500 510 520
pF1KB5 NEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLM
230 240 250 260 270 280
530 540 550 560 570 580
pF1KB5 DPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYD
290 300 310 320 330 340
590 600 610 620 630 640
pF1KB5 LRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKN
350 360 370 380 390 400
650 660 670 680 690 700
pF1KB5 FVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVC
410 420 430 440 450 460
710 720 730
pF1KB5 WRALPDGESNVLIAANSQGTIKVLELV
:::::::::::::::::::::::::::
NP_001 WRALPDGESNVLIAANSQGTIKVLELV
470 480 490
>>XP_006711550 (OMIM: 608067) PREDICTED: E3 ubiquitin-pr (708 aa)
initn: 3025 init1: 3025 opt: 3059 Z-score: 1842.5 bits: 351.5 E(85289): 6.9e-96
Smith-Waterman score: 4666; 96.9% identity (96.9% similar) in 731 aa overlap (1-731:1-708)
10 20 30 40 50 60
pF1KB5 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
:::::::::::::: :::::::::::::::::::::::
XP_006 MLELLVQKKKQLEA-----------------------QLEQIQKELSVLEEDIKRVEEMS
250 260 270
310 320 330 340 350 360
pF1KB5 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB5 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB5 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB5 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB5 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
640 650 660 670 680 690
730
pF1KB5 SQGTIKVLELV
:::::::::::
XP_006 SQGTIKVLELV
700
>>XP_005245505 (OMIM: 608067) PREDICTED: E3 ubiquitin-pr (711 aa)
initn: 2911 init1: 2911 opt: 2960 Z-score: 1783.4 bits: 340.6 E(85289): 1.3e-92
Smith-Waterman score: 4696; 97.3% identity (97.3% similar) in 731 aa overlap (1-731:1-711)
10 20 30 40 50 60
pF1KB5 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
:::::::::::::::::::::::::::::::::::: ::::
XP_005 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKR--------------------EEMS
250 260 270 280
310 320 330 340 350 360
pF1KB5 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB5 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB5 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB5 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB5 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB5 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
650 660 670 680 690 700
730
pF1KB5 SQGTIKVLELV
:::::::::::
XP_005 SQGTIKVLELV
710
731 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:52:38 2016 done: Sun Nov 6 05:52:40 2016
Total Scan time: 13.970 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]