Result of FASTA (ccds) for
pFN21AB5624
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5624, 2286 aa
1>>>pF1KB5624 2286 - 2286 aa - 2286 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6944+/-0.0013; mu= 13.4862+/- 0.078
mean_var=113.2097+/-22.567, 0's: 0 Z-trim(103.5): 18 B-trim: 163 in 1/49
Lambda= 0.120540
statistics sampled from 7446 (7452) to 7446 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.563), E-opt: 0.2 (0.229), width: 16
Scan time: 4.120
The best scores are: opt bits E(32554)
CCDS9278.1 POLE gene_id:5426|Hs108|chr12 (2286) 15330 2678.5 0
>>CCDS9278.1 POLE gene_id:5426|Hs108|chr12 (2286 aa)
initn: 15330 init1: 15330 opt: 15330 Z-score: 14400.8 bits: 2678.5 E(32554): 0
Smith-Waterman score: 15330; 100.0% identity (100.0% similar) in 2286 aa overlap (1-2286:1-2286)
10 20 30 40 50 60
pF1KB5 MSLRSGGRRRADPGADGEASRDDGATSSVSALKRLERSQWTDKMDLRFGFERLKEPGEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 MSLRSGGRRRADPGADGEASRDDGATSSVSALKRLERSQWTDKMDLRFGFERLKEPGEKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GWLINMHPTEILDEDKRLGSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 GWLINMHPTEILDEDKRLGSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 SKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIRLSFHTVEDLVKVRKEISPAVKKNREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 SKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIRLSFHTVEDLVKVRKEISPAVKKNREQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DHASDAYTALLSSVLQRGGVITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLKIHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 DHASDAYTALLSSVLQRGGVITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLKIHV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AHWYNVRYRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 AHWYNVRYRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEAHLIQRWFEHVQETKPTIMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 DGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEAHLIQRWFEHVQETKPTIMV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 TYNGDFFDWPFVEARAAVHGLSMQQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 TYNGDFFDWPFVEARAAVHGLSMQQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 SHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTLRHALEEEEKVPVEQVTNFEEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTLRHALEEEEKVPVEQVTNFEEVC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 DEIKSKLASLKDVPSRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 DEIKSKLASLKDVPSRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 ANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 ANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 RRLADYCRKAYKKIHITKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 RRLADYCRKAYKKIHITKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 AAVEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 AAVEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVFKTTNVKKPKVTISYPGAMLNIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVFKTTNVKKPKVTISYPGAMLNIM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB5 VKEGFTNDQYQELAEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 VKEGFTNDQYQELAEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB5 EDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 EDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB5 AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB5 SRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRAILDWDYYIERLGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 SRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRAILDWDYYIERLGSA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB5 IQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVYKQKKISELFTLEGRRQVTMAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 IQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVYKQKKISELFTLEGRRQVTMAEA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB5 SEDSPRPSAPDMEDFGLVKLPHPAAPVTVKRKRVLWESQEESQDLTPTVPWQEILGQPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 SEDSPRPSAPDMEDFGLVKLPHPAAPVTVKRKRVLWESQEESQDLTPTVPWQEILGQPPA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB5 LGTSQEEWLVWLRFHKKKWQLQARQRLARRKRQRLESAEGVLRPGAIRDGPATGLGSFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 LGTSQEEWLVWLRFHKKKWQLQARQRLARRKRQRLESAEGVLRPGAIRDGPATGLGSFLR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB5 RTARSILDLPWQIVQISETSQAGLFRLWALVGSDLHCIRLSIPRVFYVNQRVAKAEEGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 RTARSILDLPWQIVQISETSQAGLFRLWALVGSDLHCIRLSIPRVFYVNQRVAKAEEGAS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB5 YRKVNRVLPRSNMVYNLYEYSVPEDMYQEHINEINAELSAPDIEGVYETQVPLLFRALVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 YRKVNRVLPRSNMVYNLYEYSVPEDMYQEHINEINAELSAPDIEGVYETQVPLLFRALVH
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB5 LGCVCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHIYLYHHAQAHKALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 LGCVCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHIYLYHHAQAHKALF
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB5 GIFIPSQRRASVFVLDTVRSNQMPSLGALYSAEHGLLLEKVGPELLPPPKHTFEVRAETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 GIFIPSQRRASVFVLDTVRSNQMPSLGALYSAEHGLLLEKVGPELLPPPKHTFEVRAETD
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB5 LKTICRAIQRFLLAYKEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKINYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 LKTICRAIQRFLLAYKEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKINYG
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB5 VLDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 VLDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRH
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB5 NHLLWLSPTARPDLGGKEADDNCLVMEFDDQATVEINSSGCYSTVCVELDLQNLAVNTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 NHLLWLSPTARPDLGGKEADDNCLVMEFDDQATVEINSSGCYSTVCVELDLQNLAVNTIL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB5 QSHHVNDMEGADSMGISFDVIQQASLEDMITGGQAASAPASYDETALCSNTFRILKSMVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 QSHHVNDMEGADSMGISFDVIQQASLEDMITGGQAASAPASYDETALCSNTFRILKSMVV
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB5 GWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 GWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLG
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB5 SSVIYANFNRIILCTKKRRVEDAIAYVEYITSSIHSKETFHSLTISFSRCWEFLLWMDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 SSVIYANFNRIILCTKKRRVEDAIAYVEYITSSIHSKETFHSLTISFSRCWEFLLWMDPS
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB5 NYGGIKGKVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 NYGGIKGKVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENNW
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB5 NILQFLPQAASCQNYFLMIVSAYIVAVYHCMKDGLRRSAPGSTPVRRRGASQLSQEAEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 NILQFLPQAASCQNYFLMIVSAYIVAVYHCMKDGLRRSAPGSTPVRRRGASQLSQEAEGA
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB5 VGALPGMITFSQDYVANELTQSFFTITQKIQKKVTGSRNSTELSEMFPVLPGSHLLLNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 VGALPGMITFSQDYVANELTQSFFTITQKIQKKVTGSRNSTELSEMFPVLPGSHLLLNNP
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB5 ALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 ALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRS
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB5 CNFCRDLDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 CNFCRDLDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLV
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB5 CLKCRGVKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHYGMSYLLETLEWLLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 CLKCRGVKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHYGMSYLLETLEWLLQK
2230 2240 2250 2260 2270 2280
pF1KB5 NPQLGH
::::::
CCDS92 NPQLGH
2286 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:29:21 2016 done: Tue Nov 8 17:29:22 2016
Total Scan time: 4.120 Total Display time: 0.240
Function used was FASTA [36.3.4 Apr, 2011]