Result of FASTA (omim) for
pFN21AB5617
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5617, 1408 aa
1>>>pF1KB5617 1408 - 1408 aa - 1408 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.9312+/-0.000985; mu= -2.7244+/- 0.058
mean_var=949.8027+/-228.313, 0's: 0 Z-trim(110.1): 1111 B-trim: 1068 in 1/50
Lambda= 0.041616
statistics sampled from 17234 (18433) to 17234 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.535), E-opt: 0.2 (0.216), width: 16
Scan time: 12.500
The best scores are: opt bits E(85289)
NP_001120972 (OMIM: 114550,164860,605074,607278,61 (1408) 9470 587.9 1.7e-166
NP_001311330 (OMIM: 114550,164860,605074,607278,61 ( 934) 5103 325.4 1.2e-87
NP_000236 (OMIM: 114550,164860,605074,607278,61670 (1390) 5103 325.7 1.5e-87
XP_011514525 (OMIM: 114550,164860,605074,607278,61 (1409) 5103 325.7 1.5e-87
NP_001311331 (OMIM: 114550,164860,605074,607278,61 ( 960) 4243 273.8 4.3e-72
XP_006716053 (OMIM: 114550,164860,605074,607278,61 ( 960) 4243 273.8 4.3e-72
NP_001305842 (OMIM: 600168,617075) macrophage-stim (1294) 1318 98.4 3.6e-19
XP_011532046 (OMIM: 600168,617075) PREDICTED: macr (1295) 1318 98.4 3.6e-19
NP_001231866 (OMIM: 600168,617075) macrophage-stim (1351) 1318 98.5 3.7e-19
XP_011532042 (OMIM: 600168,617075) PREDICTED: macr (1352) 1318 98.5 3.7e-19
XP_011532041 (OMIM: 600168,617075) PREDICTED: macr (1361) 1318 98.5 3.7e-19
NP_002438 (OMIM: 600168,617075) macrophage-stimula (1400) 1318 98.5 3.8e-19
XP_005265227 (OMIM: 600168,617075) PREDICTED: macr (1401) 1318 98.5 3.8e-19
XP_011532043 (OMIM: 600168,617075) PREDICTED: macr (1332) 1289 96.7 1.2e-18
XP_011532044 (OMIM: 600168,617075) PREDICTED: macr (1324) 908 73.8 9.4e-12
XP_016858654 (OMIM: 604705,613862) PREDICTED: tyro ( 594) 847 69.5 8.3e-11
XP_016858653 (OMIM: 604705,613862) PREDICTED: tyro ( 936) 847 69.9 1e-10
XP_011508792 (OMIM: 604705,613862) PREDICTED: tyro ( 936) 847 69.9 1e-10
NP_006334 (OMIM: 604705,613862) tyrosine-protein k ( 999) 847 70.0 1.1e-10
NP_001265528 (OMIM: 109135) tyrosine-protein kinas ( 626) 793 66.3 8e-10
NP_001690 (OMIM: 109135) tyrosine-protein kinase r ( 885) 793 66.6 9.4e-10
NP_068713 (OMIM: 109135) tyrosine-protein kinase r ( 894) 793 66.6 9.5e-10
XP_005263622 (OMIM: 604705,613862) PREDICTED: tyro ( 832) 762 64.7 3.3e-09
NP_001005861 (OMIM: 600524) tyrosine-protein kinas ( 610) 733 62.7 9.7e-09
XP_016862505 (OMIM: 600524) PREDICTED: tyrosine-pr ( 411) 727 62.0 1e-08
NP_002949 (OMIM: 600524) tyrosine-protein kinase R ( 607) 724 62.2 1.4e-08
XP_011519819 (OMIM: 147370,270450) PREDICTED: insu ( 922) 716 62.0 2.4e-08
NP_001317193 (OMIM: 600341) tyrosine-protein kinas ( 845) 714 61.8 2.5e-08
XP_011519818 (OMIM: 147370,270450) PREDICTED: insu (1064) 716 62.1 2.5e-08
NP_006284 (OMIM: 600341) tyrosine-protein kinase r ( 890) 714 61.9 2.5e-08
XP_016877628 (OMIM: 147370,270450) PREDICTED: insu (1246) 716 62.3 2.7e-08
NP_001278787 (OMIM: 147370,270450) insulin-like gr (1366) 716 62.3 2.8e-08
NP_000866 (OMIM: 147370,270450) insulin-like growt (1367) 716 62.3 2.8e-08
XP_016877627 (OMIM: 147370,270450) PREDICTED: insu (1391) 716 62.3 2.9e-08
XP_016877626 (OMIM: 147370,270450) PREDICTED: insu (1392) 716 62.3 2.9e-08
XP_016877625 (OMIM: 147370,270450) PREDICTED: insu (1392) 716 62.3 2.9e-08
XP_011526291 (OMIM: 147670,246200,262190,609968,61 (1369) 706 61.7 4.3e-08
NP_001073285 (OMIM: 147670,246200,262190,609968,61 (1370) 706 61.7 4.3e-08
XP_011526290 (OMIM: 147670,246200,262190,609968,61 (1381) 706 61.7 4.3e-08
NP_000199 (OMIM: 147670,246200,262190,609968,61054 (1382) 706 61.7 4.3e-08
NP_001129473 (OMIM: 164690) Abelson tyrosine-prote ( 542) 682 59.6 7.6e-08
NP_055030 (OMIM: 147671) insulin receptor-related (1297) 690 60.7 8.1e-08
NP_001161711 (OMIM: 164690) Abelson tyrosine-prote (1043) 687 60.4 8.4e-08
NP_001161710 (OMIM: 164690) Abelson tyrosine-prote (1058) 687 60.4 8.4e-08
NP_001129472 (OMIM: 164690) Abelson tyrosine-prote (1064) 687 60.4 8.4e-08
NP_001161709 (OMIM: 164690) Abelson tyrosine-prote (1079) 687 60.4 8.5e-08
XP_005245145 (OMIM: 164690) PREDICTED: Abelson tyr (1146) 687 60.5 8.7e-08
NP_001161708 (OMIM: 164690) Abelson tyrosine-prote (1161) 687 60.5 8.8e-08
NP_005149 (OMIM: 164690) Abelson tyrosine-protein (1167) 687 60.5 8.8e-08
NP_009298 (OMIM: 164690) Abelson tyrosine-protein (1182) 687 60.5 8.9e-08
>>NP_001120972 (OMIM: 114550,164860,605074,607278,616705 (1408 aa)
initn: 9470 init1: 9470 opt: 9470 Z-score: 3109.9 bits: 587.9 E(85289): 1.7e-166
Smith-Waterman score: 9470; 100.0% identity (100.0% similar) in 1408 aa overlap (1-1408:1-1408)
10 20 30 40 50 60
pF1KB5 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB5 ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB5 TALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB5 YRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB5 VQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB5 QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB5 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTG
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB5 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB5 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCV
1330 1340 1350 1360 1370 1380
1390 1400
pF1KB5 APYPSLLSSEDNADDEVDTRPASFWETS
::::::::::::::::::::::::::::
NP_001 APYPSLLSSEDNADDEVDTRPASFWETS
1390 1400
>>NP_001311330 (OMIM: 114550,164860,605074,607278,616705 (934 aa)
initn: 5103 init1: 5103 opt: 5103 Z-score: 1694.4 bits: 325.4 E(85289): 1.2e-87
Smith-Waterman score: 6080; 98.1% identity (98.1% similar) in 928 aa overlap (1-928:1-910)
10 20 30 40 50 60
pF1KB5 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITG
::::::::::::::::::::::::::::::::::: :::::::
NP_001 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFIS------------------GGSTITG
730 740 750 760
790 800 810 820 830 840
pF1KB5 VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM
770 780 790 800 810 820
850 860 870 880 890 900
pF1KB5 LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC
830 840 850 860 870 880
910 920 930 940 950 960
pF1KB5 ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS
::::::::::::::::::::::::::::
NP_001 ENIHLHSEAVLCTVPNDLLKLNSELNIEVGFLHSSHDVNKEASVIMLFSGLK
890 900 910 920 930
>>NP_000236 (OMIM: 114550,164860,605074,607278,616705) h (1390 aa)
initn: 5103 init1: 5103 opt: 5103 Z-score: 1693.0 bits: 325.7 E(85289): 1.5e-87
Smith-Waterman score: 9288; 98.7% identity (98.7% similar) in 1408 aa overlap (1-1408:1-1390)
10 20 30 40 50 60
pF1KB5 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITG
::::::::::::::::::::::::::::::::::: :::::::
NP_000 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFIS------------------GGSTITG
730 740 750 760
790 800 810 820 830 840
pF1KB5 VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM
770 780 790 800 810 820
850 860 870 880 890 900
pF1KB5 LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC
830 840 850 860 870 880
910 920 930 940 950 960
pF1KB5 ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KB5 TALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVD
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KB5 YRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPEL
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KB5 VQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVS
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KB5 QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLI
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KB5 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTG
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KB5 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRL
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KB5 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCV
1310 1320 1330 1340 1350 1360
1390 1400
pF1KB5 APYPSLLSSEDNADDEVDTRPASFWETS
::::::::::::::::::::::::::::
NP_000 APYPSLLSSEDNADDEVDTRPASFWETS
1370 1380 1390
>>XP_011514525 (OMIM: 114550,164860,605074,607278,616705 (1409 aa)
initn: 5103 init1: 5103 opt: 5103 Z-score: 1692.9 bits: 325.7 E(85289): 1.5e-87
Smith-Waterman score: 9288; 98.7% identity (98.7% similar) in 1408 aa overlap (1-1408:20-1409)
10 20 30 40
pF1KB5 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKY
:::::::::::::::::::::::::::::::::::::::::
XP_011 MKSKSKSLAECFPYDKPLIMKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 QLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 SSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 FSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKE
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB5 TKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRF
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 CSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDI
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB5 LFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRT
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB5 LLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGR
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB5 FMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCR
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB5 HFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRL
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB5 TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIIS
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB5 NGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB5 VSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFIS------
730 740 750 760 770
770 780 790 800 810 820
pF1KB5 LNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTT
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ------------GGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTT
780 790 800 810 820
830 840 850 860 870 880
pF1KB5 PSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGN
830 840 850 860 870 880
890 900 910 920 930 940
pF1KB5 DIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKV
890 900 910 920 930 940
950 960 970 980 990 1000
pF1KB5 IVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRL
950 960 970 980 990 1000
1010 1020 1030 1040 1050 1060
pF1KB5 VSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDIS
1010 1020 1030 1040 1050 1060
1070 1080 1090 1100 1110 1120
pF1KB5 SPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGK
1070 1080 1090 1100 1110 1120
1130 1140 1150 1160 1170 1180
pF1KB5 KIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHG
1130 1140 1150 1160 1170 1180
1190 1200 1210 1220 1230 1240
pF1KB5 DLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADF
1190 1200 1210 1220 1230 1240
1250 1260 1270 1280 1290 1300
pF1KB5 GLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPP
1250 1260 1270 1280 1290 1300
1310 1320 1330 1340 1350 1360
pF1KB5 YPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFST
1310 1320 1330 1340 1350 1360
1370 1380 1390 1400
pF1KB5 FIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPASFWETS
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPASFWETS
1370 1380 1390 1400
>>NP_001311331 (OMIM: 114550,164860,605074,607278,616705 (960 aa)
initn: 4243 init1: 4243 opt: 4243 Z-score: 1415.2 bits: 273.8 E(85289): 4.3e-72
Smith-Waterman score: 6369; 98.2% identity (98.2% similar) in 978 aa overlap (431-1408:1-960)
410 420 430 440 450 460
pF1KB5 TLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEG
::::::::::::::::::::::::::::::
NP_001 MGQFSEVLLTSISTFIKGDLTIANLGTSEG
10 20 30
470 480 490 500 510 520
pF1KB5 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
40 50 60 70 80 90
530 540 550 560 570 580
pF1KB5 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
100 110 120 130 140 150
590 600 610 620 630 640
pF1KB5 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
160 170 180 190 200 210
650 660 670 680 690 700
pF1KB5 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
220 230 240 250 260 270
710 720 730 740 750 760
pF1KB5 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFIS-----
280 290 300 310 320
770 780 790 800 810 820
pF1KB5 PLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCT
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------------GGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCT
330 340 350 360 370
830 840 850 860 870 880
pF1KB5 TPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKG
380 390 400 410 420 430
890 900 910 920 930 940
pF1KB5 NDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGK
440 450 460 470 480 490
950 960 970 980 990 1000
pF1KB5 VIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDR
500 510 520 530 540 550
1010 1020 1030 1040 1050 1060
pF1KB5 LVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDI
560 570 580 590 600 610
1070 1080 1090 1100 1110 1120
pF1KB5 SSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDG
620 630 640 650 660 670
1130 1140 1150 1160 1170 1180
pF1KB5 KKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKH
680 690 700 710 720 730
1190 1200 1210 1220 1230 1240
pF1KB5 GDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVAD
740 750 760 770 780 790
1250 1260 1270 1280 1290 1300
pF1KB5 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP
800 810 820 830 840 850
1310 1320 1330 1340 1350 1360
pF1KB5 PYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFS
860 870 880 890 900 910
1370 1380 1390 1400
pF1KB5 TFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPASFWETS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPASFWETS
920 930 940 950 960
>>XP_006716053 (OMIM: 114550,164860,605074,607278,616705 (960 aa)
initn: 4243 init1: 4243 opt: 4243 Z-score: 1415.2 bits: 273.8 E(85289): 4.3e-72
Smith-Waterman score: 6369; 98.2% identity (98.2% similar) in 978 aa overlap (431-1408:1-960)
410 420 430 440 450 460
pF1KB5 TLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEG
::::::::::::::::::::::::::::::
XP_006 MGQFSEVLLTSISTFIKGDLTIANLGTSEG
10 20 30
470 480 490 500 510 520
pF1KB5 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
40 50 60 70 80 90
530 540 550 560 570 580
pF1KB5 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
100 110 120 130 140 150
590 600 610 620 630 640
pF1KB5 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
160 170 180 190 200 210
650 660 670 680 690 700
pF1KB5 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
220 230 240 250 260 270
710 720 730 740 750 760
pF1KB5 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFIS-----
280 290 300 310 320
770 780 790 800 810 820
pF1KB5 PLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCT
:::::::::::::::::::::::::::::::::::::::::::::::
XP_006 -------------GGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCT
330 340 350 360 370
830 840 850 860 870 880
pF1KB5 TPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKG
380 390 400 410 420 430
890 900 910 920 930 940
pF1KB5 NDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGK
440 450 460 470 480 490
950 960 970 980 990 1000
pF1KB5 VIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDR
500 510 520 530 540 550
1010 1020 1030 1040 1050 1060
pF1KB5 LVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDI
560 570 580 590 600 610
1070 1080 1090 1100 1110 1120
pF1KB5 SSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDG
620 630 640 650 660 670
1130 1140 1150 1160 1170 1180
pF1KB5 KKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKH
680 690 700 710 720 730
1190 1200 1210 1220 1230 1240
pF1KB5 GDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVAD
740 750 760 770 780 790
1250 1260 1270 1280 1290 1300
pF1KB5 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP
800 810 820 830 840 850
1310 1320 1330 1340 1350 1360
pF1KB5 PYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFS
860 870 880 890 900 910
1370 1380 1390 1400
pF1KB5 TFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPASFWETS
::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPASFWETS
920 930 940 950 960
>>NP_001305842 (OMIM: 600168,617075) macrophage-stimulat (1294 aa)
initn: 2074 init1: 1269 opt: 1318 Z-score: 465.1 bits: 98.4 E(85289): 3.6e-19
Smith-Waterman score: 2297; 33.0% identity (57.9% similar) in 1414 aa overlap (7-1377:7-1257)
10 20 30 40 50
pF1KB5 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
: ..:.::. .. . :: : .. . . ..:: .:.:.: .: ..
NP_001 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
.: .:.. : ..::. ::..: :::. . : : : :. . :
NP_001 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
:. . .::.: :.:::: .: : : . . :: . :.:: . ..:..:
NP_001 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
::::.: ::..: . . :.:....... . .:.:.:::: .:: :..
NP_001 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
180 190 200 210 220 230
240 250 260 270 280
pF1KB5 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
..:::. :: :.:::.:... :.:::::: .. : ...:::. :. . . :
NP_001 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
.: :. :.: .. ::..:.. . . . .:..:. . ::::: ... . ....:::::
NP_001 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNS
. .: . :..::::: :... ..... :: . .: :
NP_001 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCE---SPVHPGL---------
360 370 380 390
410 420 430 440 450 460
pF1KB5 SGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVV
:: .:.:..
NP_001 -----RRG------------LDFFQS----------------------------------
400
470 480 490 500 510 520
pF1KB5 VSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSC
:: . .:: ..:..: ::::: .:
NP_001 -----PS-------FCPNPV------------------------FQVPIQGPGCRHFLTC
410 420
530 540 550 560 570 580
pF1KB5 SQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGW
..:: : :. :::: . : ...:: :.: :. : : . . :.:.::.:.::::.::
NP_001 GRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPHSGPLRGSTRLTLCGS
430 440 450 460 470 480
590 600 610 620 630
pF1KB5 DFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNTLKCTVGPAMNKHF--
.: .. .. .: .:. : ..:. .. ..: . : ..
NP_001 NFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFECELEPLGTQAVGP
490 500 510 520 530 540
640 650 660 670 680
pF1KB5 -NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSG
:.:. ..: :. ::. ::...::. ...: .:: :::: ::: :. :. :
NP_001 TNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAGGTCLTLEGQSLSVG
550 560 570 580 590 600
690 700 710 720 730 740
pF1KB5 NSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLANRETS-IFSYREDPIV
.:: . ..: : : ::.. : : :: . . ..:.. :. : :.:::::.:
NP_001 TSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQVPGSWTFQYREDPVV
610 620 630 640 650 660
750 760 770 780 790 800
pF1KB5 YEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGRNF
: :. ..:. : :: :..:.:. ..:.. :.. :
NP_001 LSISPNCGYIN--------------------SHITICGQHLTSAW--HLVLSFHDGLRAV
670 680 690 700
810 820 830 840 850 860
pF1KB5 TVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEK
:. :. : : : . : . . :: . . . : : .
NP_001 ESRCE-RQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSAN
710 720 730 740 750 760
870 880 890 900 910 920
pF1KB5 PVMISMGNENV-LEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNS
: .. .. . .: : . : : . ::..::.. ..... :.: .: .: ..
NP_001 LVPLKPEEHAIKFEYIGLGAVADCV-GINVTVGGESCQH-EFRGDMVVCPLPPSLQLGQD
770 780 790 800 810 820
930 940 950 960 970
pF1KB5 ELNIEWKQAISSTVLGKVIVQ-----PDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQ
.. .::.:. :.... :.. .. . .:: : : : . :::
NP_001 GAPLQVCVDGECHILGRVVRPGPDGVPQSTLLGILLPLLLLVAALATALVFSYWWR-RKQ
830 840 850 860 870 880
980 990 1000 1010 1020 1030
pF1KB5 IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPEDQFPNSSQNG
. : :.:. :.: ... .: . . . :::. . .: .
NP_001 L-------------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGL---ALPAIDGLD
890 900 910 920
1040 1050 1060 1070 1080 1090
pF1KB5 SCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVH
: :. . ....... :::.. :.: :. :. :. :.: ...:
NP_001 STTCVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVLIPHERVVTH
930 940 950 960 970
1100 1110 1120 1130 1140 1150
pF1KB5 FNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV
..:::.:::: :::: .:. ..:.::.:::.:::.. .: :: ::..:. ..::::
NP_001 SDRVIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNV
980 990 1000 1010 1020 1030
1160 1170 1180 1190 1200 1210
pF1KB5 LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKK
:.:.:: : :: : :.:::: :::: .:::. .::::::::.::::::.::.::: .:
NP_001 LALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQK
1040 1050 1060 1070 1080 1090
1220 1230 1240 1250 1260 1270
pF1KB5 FVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQK
:::::::::::::::.:::::::::::::. :.:::::... :.::::::::::::: .
NP_001 FVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYR
1100 1110 1120 1130 1140 1150
1280 1290 1300 1310 1320 1330
pF1KB5 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
:::::::::::::::::.::::::: .. ::.: .: ::::: ::::::: ::.:: .:
NP_001 FTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPDSLYQVMQQC
1160 1170 1180 1190 1200 1210
1340 1350 1360 1370 1380 1390
pF1KB5 WHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEV
:. .::.: ::... : :...:.:::.. :::.:.
NP_001 WEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTSHEMNVRPEQPQFSPM
1220 1230 1240 1250 1260 1270
1400
pF1KB5 DTRPASFWETS
NP_001 PGNVRRPRPLSEPPRPT
1280 1290
>>XP_011532046 (OMIM: 600168,617075) PREDICTED: macropha (1295 aa)
initn: 2019 init1: 1269 opt: 1318 Z-score: 465.1 bits: 98.4 E(85289): 3.6e-19
Smith-Waterman score: 2288; 32.9% identity (57.9% similar) in 1414 aa overlap (7-1377:7-1258)
10 20 30 40 50
pF1KB5 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
: ..:.::. .. . :: : .. . . ..:: .:.:.: .: ..
XP_011 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
.: .:.. : ..::. ::..: :::. . : : : :. . :
XP_011 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
:. . .::.: :.:::: .: : : . . :: . :.:: . ..:..:
XP_011 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
::::.: ::..: . . :.:....... . .:.:.:::: .:: :..
XP_011 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
180 190 200 210 220 230
240 250 260 270 280
pF1KB5 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
..:::. :: :.:::.:... :.:::::: .. : ...:::. :. . . :
XP_011 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
.: :. :.: .. ::..:.. . . . .:..:. . ::::: ... . ....:::::
XP_011 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNS
. .: . :..::::: :... ..... :: . .: :
XP_011 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCE---SPVHPGL---------
360 370 380 390
410 420 430 440 450 460
pF1KB5 SGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVV
:: .:.:..
XP_011 -----RRG------------LDFFQS----------------------------------
400
470 480 490 500 510 520
pF1KB5 VSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSC
:: . .:: ..:..: ::::: .:
XP_011 -----PS-------FCPNPV------------------------FQVPIQGPGCRHFLTC
410 420
530 540 550 560 570 580
pF1KB5 SQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGW
..:: : :. :::: . : ...:: :.: :. : : . . :.:.::.:.::::.::
XP_011 GRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPHSGPLRGSTRLTLCGS
430 440 450 460 470 480
590 600 610 620 630
pF1KB5 DFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNTLKCTVGPAMNKHF--
.: .. .. .: .:. : ..:. .. ..: . : ..
XP_011 NFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFECELEPLGTQAVGP
490 500 510 520 530 540
640 650 660 670 680
pF1KB5 -NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSG
:.:. ..: :. ::. ::...::. ...: .:: :::: ::: :. :. :
XP_011 TNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAGGTCLTLEGQSLSVG
550 560 570 580 590 600
690 700 710 720 730 740
pF1KB5 NSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLANRETS-IFSYREDPIV
.:: . ..: : : ::.. : : :: . . ..:.. :. : :.:::::.:
XP_011 TSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQVPGSWTFQYREDPVV
610 620 630 640 650 660
750 760 770 780 790 800
pF1KB5 YEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGRNF
: :. ..:. : :: :..:.:. ..:.. :.. :
XP_011 LSISPNCGYIN--------------------SHITICGQHLTSAW--HLVLSFHDGLRAV
670 680 690 700
810 820 830 840 850 860
pF1KB5 TVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEK
.:. : : : . : . . :: . . . : : .
XP_011 ESRQCERQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSAN
710 720 730 740 750 760
870 880 890 900 910 920
pF1KB5 PVMISMGNENV-LEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNS
: .. .. . .: : . : : . ::..::.. ..... :.: .: .: ..
XP_011 LVPLKPEEHAIKFEYIGLGAVADCV-GINVTVGGESCQH-EFRGDMVVCPLPPSLQLGQD
770 780 790 800 810 820
930 940 950 960 970
pF1KB5 ELNIEWKQAISSTVLGKVIVQ-----PDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQ
.. .::.:. :.... :.. .. . .:: : : : . :::
XP_011 GAPLQVCVDGECHILGRVVRPGPDGVPQSTLLGILLPLLLLVAALATALVFSYWWR-RKQ
830 840 850 860 870 880
980 990 1000 1010 1020 1030
pF1KB5 IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPEDQFPNSSQNG
. : :.:. :.: ... .: . . . :::. . .: .
XP_011 L-------------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGL---ALPAIDGLD
890 900 910 920
1040 1050 1060 1070 1080 1090
pF1KB5 SCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVH
: :. . ....... :::.. :.: :. :. :. :.: ...:
XP_011 STTCVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVLIPHERVVTH
930 940 950 960 970
1100 1110 1120 1130 1140 1150
pF1KB5 FNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV
..:::.:::: :::: .:. ..:.::.:::.:::.. .: :: ::..:. ..::::
XP_011 SDRVIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNV
980 990 1000 1010 1020 1030
1160 1170 1180 1190 1200 1210
pF1KB5 LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKK
:.:.:: : :: : :.:::: :::: .:::. .::::::::.::::::.::.::: .:
XP_011 LALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQK
1040 1050 1060 1070 1080 1090
1220 1230 1240 1250 1260 1270
pF1KB5 FVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQK
:::::::::::::::.:::::::::::::. :.:::::... :.::::::::::::: .
XP_011 FVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYR
1100 1110 1120 1130 1140 1150
1280 1290 1300 1310 1320 1330
pF1KB5 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
:::::::::::::::::.::::::: .. ::.: .: ::::: ::::::: ::.:: .:
XP_011 FTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPDSLYQVMQQC
1160 1170 1180 1190 1200 1210
1340 1350 1360 1370 1380 1390
pF1KB5 WHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEV
:. .::.: ::... : :...:.:::.. :::.:.
XP_011 WEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTSHEMNVRPEQPQFSPM
1220 1230 1240 1250 1260 1270
1400
pF1KB5 DTRPASFWETS
XP_011 PGNVRRPRPLSEPPRPT
1280 1290
>>NP_001231866 (OMIM: 600168,617075) macrophage-stimulat (1351 aa)
initn: 2283 init1: 1269 opt: 1318 Z-score: 464.9 bits: 98.5 E(85289): 3.7e-19
Smith-Waterman score: 2500; 35.0% identity (60.7% similar) in 1423 aa overlap (7-1377:7-1314)
10 20 30 40 50
pF1KB5 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
: ..:.::. .. . :: : .. . . ..:: .:.:.: .: ..
NP_001 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
.: .:.. : ..::. ::..: :::. . : : : :. . :
NP_001 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
:. . .::.: :.:::: .: : : . . :: . :.:: . ..:..:
NP_001 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
::::.: ::..: . . :.:....... . .:.:.:::: .:: :..
NP_001 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
180 190 200 210 220 230
240 250 260 270 280
pF1KB5 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
..:::. :: :.:::.:... :.:::::: .. : ...:::. :. . . :
NP_001 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
.: :. :.: .. ::..:.. . . . .:..:. . ::::: ... . ....:::::
NP_001 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
300 310 320 330 340 350
350 360 370 380 390
pF1KB5 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRC------------LQHFYGPNH
. .: . :..::::: :... ..... :: :. : .:.
NP_001 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPS-
360 370 380 390 400
400 410 420 430 440 450
pF1KB5 EHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIAN
: : :. : . : .. .....::::: : .. : .:.. . ..:.:.
NP_001 -FCPNPPGLEALSPNTSCR-HFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAH
410 420 430 440 450 460
460 470 480 490 500 510
pF1KB5 LGTSEGRFMQVVVSRSGPSTPHV-NFLL-DS-HPVSPEVIVEHTLNQNGYTLVITGKKIT
.:: .::..:: . :: .: :: : :: .::. .: . . : .: ..
NP_001 MGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVS-----RLGDHLLFASGDQVF
470 480 490 500 510
520 530 540 550 560 570
pF1KB5 KIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPN
..:..: ::::: .:..:: : :. :::: . : ...:: :.: :. : : . . :.
NP_001 QVPIQGPGCRHFLTCGRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPH
520 530 540 550 560 570
580 590 600 610 620
pF1KB5 SAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNT
:.::.:.::::.:: .: .. .. .: .:. : ..:. ..
NP_001 SGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEE
580 590 600 610 620 630
630 640 650 660 670
pF1KB5 LKCTVGPAMNKHF---NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMA
..: . : .. :.:. ..: :. ::. ::...::. ...: .:: :
NP_001 FECELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRA
640 650 660 670 680 690
680 690 700 710 720 730
pF1KB5 GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN
::: ::: :. :. :.:: . ..: : : ::.. : : :: . . ..:.. :.
NP_001 GGTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQ
700 710 720 730 740 750
740 750 760 770 780
pF1KB5 RETS-IFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVS
: :.:::::.: : :. ..:. : :: :..:.:.
NP_001 VPGSWTFQYREDPVVLSISPNCGYIN--------------------SHITICGQHLTSAW
760 770 780 790
790 800 810 820 830 840
pF1KB5 VPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYF
..:.. :.. : :. :. : : : . : . . :: . :
NP_001 --HLVLSFHDGLRAVESRCE-RQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDG--AAGF
800 810 820 830 840 850
850 860 870 880 890 900
pF1KB5 DLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEA
: : :. . : : :.. .: .. .:.: :: :. : :. ..
NP_001 TL-----PGFRFLPPPHPPS---ANLVPLKPEE---HAIKFEVCVDGE--C---HILGR-
860 870 880 890
910 920 930 940 950 960
pF1KB5 VLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGF
:. :. . . ::.:: :. : :. :....:::. :
NP_001 VVRPGPDGVPQ--------------STLLG--ILLP------LLLLVAALATALV----F
900 910 920
970 980 990 1000 1010 1020
pF1KB5 FLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPED
: . :::. : :.:. :.: ... .: . . . :::. .
NP_001 SYWWR-RKQL-------------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGL---
930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KB5 QFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVV
.: . : :. . ....... :::.. :.: :. :. :. :.
NP_001 ALPAIDGLDSTTCVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVL
980 990 1000 1010 1020
1090 1100 1110 1120 1130 1140
pF1KB5 IGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGII
: ...: ..:::.:::: :::: .:. ..:.::.:::.:::.. .: :: ::..
NP_001 IPHERVVTHSDRVIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLL
1030 1040 1050 1060 1070 1080
1150 1160 1170 1180 1190 1200
pF1KB5 MKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAK
:. ..:::::.:.:: : :: : :.:::: :::: .:::. .::::::::.::::::.
NP_001 MRGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVAR
1090 1100 1110 1120 1130 1140
1210 1220 1230 1240 1250 1260
pF1KB5 GMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWM
::.::: .::::::::::::::::.:::::::::::::. :.:::::... :.::::::
NP_001 GMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWM
1150 1160 1170 1180 1190 1200
1270 1280 1290 1300 1310 1320
pF1KB5 ALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPD
::::::: .:::::::::::::::::.::::::: .. ::.: .: ::::: :::::::
NP_001 ALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPD
1210 1220 1230 1240 1250 1260
1330 1340 1350 1360 1370 1380
pF1KB5 PLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLS
::.:: .::. .::.: ::... : :...:.:::.. :::.:.
NP_001 SLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTSHEMNVR
1270 1280 1290 1300 1310 1320
1390 1400
pF1KB5 SEDNADDEVDTRPASFWETS
NP_001 PEQPQFSPMPGNVRRPRPLSEPPRPT
1330 1340 1350
>>XP_011532042 (OMIM: 600168,617075) PREDICTED: macropha (1352 aa)
initn: 2228 init1: 1269 opt: 1318 Z-score: 464.9 bits: 98.5 E(85289): 3.7e-19
Smith-Waterman score: 2491; 34.9% identity (60.6% similar) in 1423 aa overlap (7-1377:7-1315)
10 20 30 40 50
pF1KB5 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
: ..:.::. .. . :: : .. . . ..:: .:.:.: .: ..
XP_011 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
.: .:.. : ..::. ::..: :::. . : : : :. . :
XP_011 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
:. . .::.: :.:::: .: : : . . :: . :.:: . ..:..:
XP_011 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
::::.: ::..: . . :.:....... . .:.:.:::: .:: :..
XP_011 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
180 190 200 210 220 230
240 250 260 270 280
pF1KB5 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
..:::. :: :.:::.:... :.:::::: .. : ...:::. :. . . :
XP_011 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
.: :. :.: .. ::..:.. . . . .:..:. . ::::: ... . ....:::::
XP_011 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
300 310 320 330 340 350
350 360 370 380 390
pF1KB5 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRC------------LQHFYGPNH
. .: . :..::::: :... ..... :: :. : .:.
XP_011 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPS-
360 370 380 390 400
400 410 420 430 440 450
pF1KB5 EHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIAN
: : :. : . : .. .....::::: : .. : .:.. . ..:.:.
XP_011 -FCPNPPGLEALSPNTSCR-HFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAH
410 420 430 440 450 460
460 470 480 490 500 510
pF1KB5 LGTSEGRFMQVVVSRSGPSTPHV-NFLL-DS-HPVSPEVIVEHTLNQNGYTLVITGKKIT
.:: .::..:: . :: .: :: : :: .::. .: . . : .: ..
XP_011 MGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVS-----RLGDHLLFASGDQVF
470 480 490 500 510
520 530 540 550 560 570
pF1KB5 KIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPN
..:..: ::::: .:..:: : :. :::: . : ...:: :.: :. : : . . :.
XP_011 QVPIQGPGCRHFLTCGRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPH
520 530 540 550 560 570
580 590 600 610 620
pF1KB5 SAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNT
:.::.:.::::.:: .: .. .. .: .:. : ..:. ..
XP_011 SGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEE
580 590 600 610 620 630
630 640 650 660 670
pF1KB5 LKCTVGPAMNKHF---NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMA
..: . : .. :.:. ..: :. ::. ::...::. ...: .:: :
XP_011 FECELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRA
640 650 660 670 680 690
680 690 700 710 720 730
pF1KB5 GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN
::: ::: :. :. :.:: . ..: : : ::.. : : :: . . ..:.. :.
XP_011 GGTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQ
700 710 720 730 740 750
740 750 760 770 780
pF1KB5 RETS-IFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVS
: :.:::::.: : :. ..:. : :: :..:.:.
XP_011 VPGSWTFQYREDPVVLSISPNCGYIN--------------------SHITICGQHLTSAW
760 770 780 790
790 800 810 820 830 840
pF1KB5 VPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYF
..:.. :.. : .:. : : : . : . . :: . :
XP_011 --HLVLSFHDGLRAVESRQCERQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDG--AAGF
800 810 820 830 840 850
850 860 870 880 890 900
pF1KB5 DLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEA
: : :. . : : :.. .: .. .:.: :: :. : :. ..
XP_011 TL-----PGFRFLPPPHPPS---ANLVPLKPEE---HAIKFEVCVDGE--C---HILGR-
860 870 880 890
910 920 930 940 950 960
pF1KB5 VLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGF
:. :. . . ::.:: :. : :. :....:::. :
XP_011 VVRPGPDGVPQ--------------STLLG--ILLP------LLLLVAALATALV----F
900 910 920 930
970 980 990 1000 1010 1020
pF1KB5 FLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPED
: . :::. : :.:. :.: ... .: . . . :::. .
XP_011 SYWWR-RKQL-------------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGL---
940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KB5 QFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVV
.: . : :. . ....... :::.. :.: :. :. :. :.
XP_011 ALPAIDGLDSTTCVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVL
980 990 1000 1010 1020
1090 1100 1110 1120 1130 1140
pF1KB5 IGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGII
: ...: ..:::.:::: :::: .:. ..:.::.:::.:::.. .: :: ::..
XP_011 IPHERVVTHSDRVIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLL
1030 1040 1050 1060 1070 1080
1150 1160 1170 1180 1190 1200
pF1KB5 MKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAK
:. ..:::::.:.:: : :: : :.:::: :::: .:::. .::::::::.::::::.
XP_011 MRGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVAR
1090 1100 1110 1120 1130 1140
1210 1220 1230 1240 1250 1260
pF1KB5 GMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWM
::.::: .::::::::::::::::.:::::::::::::. :.:::::... :.::::::
XP_011 GMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWM
1150 1160 1170 1180 1190 1200
1270 1280 1290 1300 1310 1320
pF1KB5 ALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPD
::::::: .:::::::::::::::::.::::::: .. ::.: .: ::::: :::::::
XP_011 ALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPD
1210 1220 1230 1240 1250 1260
1330 1340 1350 1360 1370 1380
pF1KB5 PLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLS
::.:: .::. .::.: ::... : :...:.:::.. :::.:.
XP_011 SLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTSHEMNVR
1270 1280 1290 1300 1310 1320
1390 1400
pF1KB5 SEDNADDEVDTRPASFWETS
XP_011 PEQPQFSPMPGNVRRPRPLSEPPRPT
1330 1340 1350
1408 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:08:51 2016 done: Tue Nov 8 17:08:53 2016
Total Scan time: 12.500 Total Display time: 0.690
Function used was FASTA [36.3.4 Apr, 2011]