Result of FASTA (omim) for
pFN21AB5261
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5261, 202 aa
1>>>pF1KB5261 202 - 202 aa - 202 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0086+/-0.000271; mu= 16.5348+/- 0.017
mean_var=77.1483+/-15.888, 0's: 0 Z-trim(121.4): 15 B-trim: 2566 in 2/50
Lambda= 0.146020
statistics sampled from 38031 (38048) to 38031 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.446), width: 16
Scan time: 6.400
The best scores are: opt bits E(85289)
NP_612141 (OMIM: 607587) interleukin-17D precursor ( 202) 1423 308.0 6.7e-84
XP_005266478 (OMIM: 607587) PREDICTED: interleukin ( 209) 1423 308.0 6.8e-84
XP_005266479 (OMIM: 607587) PREDICTED: interleukin ( 114) 745 165.0 4.3e-41
NP_037410 (OMIM: 604628) interleukin-17C precursor ( 197) 272 65.5 6.4e-11
NP_055258 (OMIM: 604627) interleukin-17B isoform 1 ( 180) 254 61.7 8.3e-10
XP_016864835 (OMIM: 604627) PREDICTED: interleukin ( 245) 255 62.0 9e-10
XP_011535924 (OMIM: 604627) PREDICTED: interleukin ( 128) 243 59.2 3.2e-09
XP_016864836 (OMIM: 604627) PREDICTED: interleukin ( 128) 243 59.2 3.2e-09
NP_001304916 (OMIM: 604627) interleukin-17B isofor ( 128) 243 59.2 3.2e-09
XP_016864837 (OMIM: 604627) PREDICTED: interleukin ( 128) 243 59.2 3.2e-09
NP_443104 (OMIM: 606496,613956) interleukin-17F pr ( 163) 216 53.6 2e-07
XP_011512578 (OMIM: 606496,613956) PREDICTED: inte ( 163) 216 53.6 2e-07
NP_002181 (OMIM: 603149) interleukin-17A precursor ( 155) 189 47.9 9.9e-06
NP_758525 (OMIM: 605658) interleukin-25 isoform 2 ( 161) 181 46.3 3.3e-05
NP_073626 (OMIM: 605658) interleukin-25 isoform 1 ( 177) 181 46.3 3.5e-05
>>NP_612141 (OMIM: 607587) interleukin-17D precursor [Ho (202 aa)
initn: 1423 init1: 1423 opt: 1423 Z-score: 1627.3 bits: 308.0 E(85289): 6.7e-84
Smith-Waterman score: 1423; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:1-202)
10 20 30 40 50 60
pF1KB5 MLVAGFLLALPPSWAAGAPRAGRRPARPRGCADRPEELLEQLYGRLAAGVLSAFHHTLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MLVAGFLLALPPSWAAGAPRAGRRPARPRGCADRPEELLEQLYGRLAAGVLSAFHHTLQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCLCRGCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 GPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCLCRGCL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TGLFGEEDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEPEKDADSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 TGLFGEEDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEPEKDADSI
130 140 150 160 170 180
190 200
pF1KB5 NSSIDKQGAKLLLGPNDAPAGP
::::::::::::::::::::::
NP_612 NSSIDKQGAKLLLGPNDAPAGP
190 200
>>XP_005266478 (OMIM: 607587) PREDICTED: interleukin-17D (209 aa)
initn: 1423 init1: 1423 opt: 1423 Z-score: 1627.1 bits: 308.0 E(85289): 6.8e-84
Smith-Waterman score: 1423; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:8-209)
10 20 30 40 50
pF1KB5 MLVAGFLLALPPSWAAGAPRAGRRPARPRGCADRPEELLEQLYGRLAAGVLSA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLGALVWMLVAGFLLALPPSWAAGAPRAGRRPARPRGCADRPEELLEQLYGRLAAGVLSA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 FHHTLQLGPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHHTLQLGPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 CLCRGCLTGLFGEEDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLCRGCLTGLFGEEDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEP
130 140 150 160 170 180
180 190 200
pF1KB5 EKDADSINSSIDKQGAKLLLGPNDAPAGP
:::::::::::::::::::::::::::::
XP_005 EKDADSINSSIDKQGAKLLLGPNDAPAGP
190 200
>>XP_005266479 (OMIM: 607587) PREDICTED: interleukin-17D (114 aa)
initn: 758 init1: 745 opt: 745 Z-score: 858.7 bits: 165.0 E(85289): 4.3e-41
Smith-Waterman score: 745; 100.0% identity (100.0% similar) in 106 aa overlap (97-202:9-114)
70 80 90 100 110 120
pF1KB5 RNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCLCRGCLTGLFGE
::::::::::::::::::::::::::::::
XP_005 MPPSYLLQRISYDPARYPRYLPEAYCLCRGCLTGLFGE
10 20 30
130 140 150 160 170 180
pF1KB5 EDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEPEKDADSINSSIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEPEKDADSINSSIDK
40 50 60 70 80 90
190 200
pF1KB5 QGAKLLLGPNDAPAGP
::::::::::::::::
XP_005 QGAKLLLGPNDAPAGP
100 110
>>NP_037410 (OMIM: 604628) interleukin-17C precursor [Ho (197 aa)
initn: 285 init1: 203 opt: 272 Z-score: 317.0 bits: 65.5 E(85289): 6.4e-11
Smith-Waterman score: 272; 33.5% identity (60.5% similar) in 167 aa overlap (17-170:32-192)
10 20 30 40
pF1KB5 MLVAGFLLALPPSWAAGAPRAGRRPARPRGCADRPEELLEQ--LYG
:.:. : : : : .:: . .:
NP_037 TLLPGLLFLTWLHTCLAHHDPSLRGHPHSHGTPHCYSAEELPLGQA--PPHLLARGAKWG
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 R-LAAGVLSAFHHTLQLGPREQARNAS-CPAGGRPADRRFRPPTNLRSVSPWAYRISYDP
. : ....:... . . : .:. .. ::. :: .. .. :. ::.::: ::.. :
NP_037 QALPVALVSSLEAASHRGRHERPSATTQCPVL-RP-EEVLEADTHQRSISPWRYRVDTDE
60 70 80 90 100 110
110 120 130 140 150
pF1KB5 ARYPRYLPEAYCLCRGCLTGLFGEEDVRFRSAPVYMPTVVLRRTPACA---------GGR
:::. : : ::::::. . :.: . . :. . . .:::: : :. :.
NP_037 DRYPQKLAFAECLCRGCIDARTGRETAALNSVRLLQSLLVLRRRP-CSRDGSGLPTPGAF
120 130 140 150 160 170
160 170 180 190 200
pF1KB5 SVYTEAYVTIPVGCTCVPEPEKDADSINSSIDKQGAKLLLGPNDAPAGP
. .:: .. .:::::::
NP_037 AFHTE-FIHVPVGCTCVLPRSV
180 190
>>NP_055258 (OMIM: 604627) interleukin-17B isoform 1 pre (180 aa)
initn: 275 init1: 205 opt: 254 Z-score: 297.0 bits: 61.7 E(85289): 8.3e-10
Smith-Waterman score: 254; 32.4% identity (56.1% similar) in 173 aa overlap (6-170:9-179)
10 20 30 40 50
pF1KB5 MLVAGFLLALPPSWAAGAPRAGRRP----ARPRGCADRPEELLEQLYGRLAAGV-LS
:::.. . : ::. . .:: : :... .: .:. . .
NP_055 MDWPHNLLFLLTISIFLGLGQPRSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARME
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 AFHHTLQLGPREQARNASCPAGGRPADRRFRP-PTNLRSVSPWAYRISYDPARYPRYLPE
...... : ::.: : : . .. .: ::.:::.: :..::.: : :::
NP_055 EYERNIEEMV-AQLRNSSELAQ-RKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPE
70 80 90 100 110
120 130 140 150 160
pF1KB5 AYCLCRGCLTGLFGEEDVRFRSAPVYMPTVVLRRT--PACAGGRSVYTEAYVTIPVGCTC
: ::: ::.. . .:: . :.::. . : :: : : .. :: :::::
NP_055 ARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTC
120 130 140 150 160 170
170 180 190 200
pF1KB5 VPEPEKDADSINSSIDKQGAKLLLGPNDAPAGP
.
NP_055 IF
180
>>XP_016864835 (OMIM: 604627) PREDICTED: interleukin-17B (245 aa)
initn: 275 init1: 205 opt: 255 Z-score: 296.4 bits: 62.0 E(85289): 9e-10
Smith-Waterman score: 255; 32.6% identity (56.0% similar) in 175 aa overlap (4-170:72-244)
10 20
pF1KB5 MLVAGFLLALPPSWAAGAPRAGRRP----ARPR
: :::.. . : ::. . .::
XP_016 TVKLTCSHTVSESGDHPRRESAVSGRPGQSALFLLTISIFLGLGQPRSPKSKRKGQGRPG
50 60 70 80 90 100
30 40 50 60 70 80
pF1KB5 GCADRPEELLEQLYGRLAAGV-LSAFHHTLQLGPREQARNASCPAGGRPADRRFRP-PTN
: :... .: .:. . . ...... : ::.: : : . .. .:
XP_016 PLAPGPHQVPLDLVSRMKPYARMEEYERNIEEMV-AQLRNSSELAQ-RKCEVNLQLWMSN
110 120 130 140 150
90 100 110 120 130 140
pF1KB5 LRSVSPWAYRISYDPARYPRYLPEAYCLCRGCLTGLFGEEDVRFRSAPVYMPTVVLRRT-
::.:::.: :..::.: : :::: ::: ::.. . .:: . :.::. . : ::
XP_016 KRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLC
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB5 -PACAGGRSVYTEAYVTIPVGCTCVPEPEKDADSINSSIDKQGAKLLLGPNDAPAGP
: : .. :: :::::.
XP_016 PPPPRTGPCRQRAVMETIAVGCTCIF
220 230 240
>>XP_011535924 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 261 init1: 205 opt: 243 Z-score: 286.5 bits: 59.2 E(85289): 3.2e-09
Smith-Waterman score: 243; 43.7% identity (63.2% similar) in 87 aa overlap (86-170:41-127)
60 70 80 90 100 110
pF1KB5 HTLQLGPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCL
.: ::.:::.: :..::.: : :::: ::
XP_011 ERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCL
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB5 CRGCLTGLFGEEDVRFRSAPVYMPTVVLRRT--PACAGGRSVYTEAYVTIPVGCTCVPEP
: ::.. . .:: . :.::. . : :: : : .. :: :::::.
XP_011 CLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
80 90 100 110 120
180 190 200
pF1KB5 EKDADSINSSIDKQGAKLLLGPNDAPAGP
>>XP_016864836 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 261 init1: 205 opt: 243 Z-score: 286.5 bits: 59.2 E(85289): 3.2e-09
Smith-Waterman score: 243; 43.7% identity (63.2% similar) in 87 aa overlap (86-170:41-127)
60 70 80 90 100 110
pF1KB5 HTLQLGPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCL
.: ::.:::.: :..::.: : :::: ::
XP_016 ERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCL
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB5 CRGCLTGLFGEEDVRFRSAPVYMPTVVLRRT--PACAGGRSVYTEAYVTIPVGCTCVPEP
: ::.. . .:: . :.::. . : :: : : .. :: :::::.
XP_016 CLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
80 90 100 110 120
180 190 200
pF1KB5 EKDADSINSSIDKQGAKLLLGPNDAPAGP
>>NP_001304916 (OMIM: 604627) interleukin-17B isoform 2 (128 aa)
initn: 261 init1: 205 opt: 243 Z-score: 286.5 bits: 59.2 E(85289): 3.2e-09
Smith-Waterman score: 243; 43.7% identity (63.2% similar) in 87 aa overlap (86-170:41-127)
60 70 80 90 100 110
pF1KB5 HTLQLGPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCL
.: ::.:::.: :..::.: : :::: ::
NP_001 ERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCL
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB5 CRGCLTGLFGEEDVRFRSAPVYMPTVVLRRT--PACAGGRSVYTEAYVTIPVGCTCVPEP
: ::.. . .:: . :.::. . : :: : : .. :: :::::.
NP_001 CLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
80 90 100 110 120
180 190 200
pF1KB5 EKDADSINSSIDKQGAKLLLGPNDAPAGP
>>XP_016864837 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 261 init1: 205 opt: 243 Z-score: 286.5 bits: 59.2 E(85289): 3.2e-09
Smith-Waterman score: 243; 43.7% identity (63.2% similar) in 87 aa overlap (86-170:41-127)
60 70 80 90 100 110
pF1KB5 HTLQLGPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCL
.: ::.:::.: :..::.: : :::: ::
XP_016 ERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCL
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB5 CRGCLTGLFGEEDVRFRSAPVYMPTVVLRRT--PACAGGRSVYTEAYVTIPVGCTCVPEP
: ::.. . .:: . :.::. . : :: : : .. :: :::::.
XP_016 CLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
80 90 100 110 120
180 190 200
pF1KB5 EKDADSINSSIDKQGAKLLLGPNDAPAGP
202 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:47:11 2016 done: Sun Nov 6 23:47:12 2016
Total Scan time: 6.400 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]