Result of FASTA (omim) for
pFN21AB3917
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3917, 1720 aa
1>>>pF1KB3917 1720 - 1720 aa - 1720 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.5535+/-0.000669; mu= 3.5959+/- 0.041
mean_var=289.2262+/-59.948, 0's: 0 Z-trim(113.3): 9 B-trim: 865 in 1/49
Lambda= 0.075415
statistics sampled from 22589 (22595) to 22589 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.589), E-opt: 0.2 (0.265), width: 16
Scan time: 15.500
The best scores are: opt bits E(85289)
NP_056240 (OMIM: 616404,616462) DNA-directed RNA p (1720) 11455 1262.4 0
NP_000928 (OMIM: 180660) DNA-directed RNA polymera (1970) 648 86.7 2.4e-15
NP_008986 (OMIM: 607694,614258) DNA-directed RNA p (1390) 485 68.8 4e-10
>>NP_056240 (OMIM: 616404,616462) DNA-directed RNA polym (1720 aa)
initn: 11455 init1: 11455 opt: 11455 Z-score: 6752.0 bits: 1262.4 E(85289): 0
Smith-Waterman score: 11455; 99.9% identity (99.9% similar) in 1720 aa overlap (1-1720:1-1720)
10 20 30 40 50 60
pF1KB3 MLISKNMPWRRLQGISFGMYSAEELKKLSVKSITNPRYLDSLGNPSANGLYDLALGPADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MLISKNMPWRRLQGISFGMYSAEELKKLSVKSITNPRYLDSLGNPSANGLYDLALGPADS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LCQLRVLEVGALQAVYELERILNRFLEENADPSASEIREELEQYTTEIVQNNLLGSQGAH
::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
NP_056 LCQLRVLEVGALQAVYELERILNRFLEENPDPSASEIREELEQYTTEIVQNNLLGSQGAH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VKNVCESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVHRTAGQKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VKNVCESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVHRTAGQKDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EPLGIEEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRFNPSVFFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EPLGIEEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRFNPSVFFLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 DEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYPGIRQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYPGIRQI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 LEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQEL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 RQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 HVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 SELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 LTDKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LTDKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKET
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 PRSVPGFNPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGKVLTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PRSVPGFNPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGKVLTC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 EVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 GAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 PPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 EDGLDIPKTQFLQPKQFPFLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EDGLDIPKTQFLQPKQFPFLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 NTLLRRGAFLSYSQKIQEAVKALKLESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NTLLRRGAFLSYSQKIQEAVKALKLESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB3 ACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKW
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB3 QRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB3 TPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEEKQNKFQVYQLRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEEKQNKFQVYQLRFQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB3 FLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB3 GELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEEN
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB3 DDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMER
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB3 RVQAVREIHPFIDDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RVQAVREIHPFIDDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGIT
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB3 RCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRV
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB3 IEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIRSNSSPLQQMTFETSFQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIRSNSSPLQQMTFETSFQF
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720
pF1KB3 LKQATMLGSHDELRSPSACLVVGKVVRGGTGLFELKQPLR
::::::::::::::::::::::::::::::::::::::::
NP_056 LKQATMLGSHDELRSPSACLVVGKVVRGGTGLFELKQPLR
1690 1700 1710 1720
>>NP_000928 (OMIM: 180660) DNA-directed RNA polymerase I (1970 aa)
initn: 1614 init1: 457 opt: 648 Z-score: 396.7 bits: 86.7 E(85289): 2.4e-15
Smith-Waterman score: 1641; 27.3% identity (52.6% similar) in 1743 aa overlap (8-1715:14-1473)
10 20 30 40 50
pF1KB3 MLISKNMPWRRLQGISFGMYSAEELKKLSVK--SITNPRYLDSLGNPSANGLYD
: : .. ..::. : .:::..:: .: :. .. : :. .::.:
NP_000 MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEG-GRPKLGGLMD
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 LALGPADSKEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTC
: . :.::. ....: ::.::::: :.. .. : . .:: :. :
NP_000 PRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFC-----
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 PRAVIHLLLCQLRVLEVGALQAVYELERILNRFLEENADPSASEIREELEQYTTEIVQNN
...: .. .:. ..: . . . . .
NP_000 ------------------------------SKLLVDSNNPKIKDILAKSKGQPKKRLTHV
120 130 140
180 190 200 210 220 230
pF1KB3 LLGSQGAHVKNVCESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVH
.: ::.::. . :. : . : . ::.. . ..
NP_000 YDLCKG---KNICEGGEE---------MDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIR
150 160 170 180 190
240 250 260 270 280 290
pF1KB3 RTAGQKDSEPLGIEEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRF
:.. . .: ..: . :. :.: ..: .. . .: : : ::: :.
NP_000 RSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVL----------GMEPRY
200 210 220 230 240
300 310 320 330 340 350
pF1KB3 N-PSVFFLDFLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKL
: ... : ::: ::. . : . .: .: . :.: : . : :.
NP_000 ARPEWMIVTVLPVPPLSVRPAVVM--QGSARNQD-DLTHKLADIVKINNQLRRNEQNGAA
250 260 270 280 290
360 370 380 390 400
pF1KB3 PEEVATPTTDEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKL--
. .: . :: :: :: . :.:. :
NP_000 AHVIAEDV--------------------------KL------LQFHVATMVDNELPGLPR
300 310 320
410 420 430 440 450 460
pF1KB3 MMDK--YP--GIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATK
:.: : ...: :. ::: : ..::::::..::.:: :: .. ...:.: .:..
NP_000 AMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAAN
330 340 350 360 370 380
470 480 490 500 510 520
pF1KB3 LTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTP
.:. . :::.:...:.. : : . .:::...: ..:.: .:. . :
NP_000 MTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDR-----IDLR---------FHP
390 400 410 420 430
530 540 550 560 570 580
pF1KB3 ATGAPKPQGTKIVCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAY
. . : : ::. .:::...:::::::. :...::.:::: ...::. . :
NP_000 KPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPW-STFRLNLSVTTPY
440 450 460 470 480 490
590 600 610 620 630 640
pF1KB3 NADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRG
:::::::::: :.::: ::: :: . .. ..:....:. :..:: ... ..: :
NP_000 NADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRD
500 510 520 530 540 550
650 660 670 680 690 700
pF1KB3 CFFTREHYMELVYRGLTDKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNL
:. : . :.:.. :. :.: .:.:::: :::::::. : ::: ::
NP_000 VFLERGEVMNLLMF-LSTWDGKVP--QPAILKPRPLWTGKQIFSL----IIP-GHINC--
560 570 580 590 600
710 720 730 740 750 760
pF1KB3 SGKAKITGKAWVKETPRSVPGFNPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCC
: .. . : : .. : ...:....:::. :.: : :.:: .:::
NP_000 -----IRTHSTHPDDEDSGP-YKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHIS
610 620 630 640 650
770 780 790 800 810 820
pF1KB3 YEIYGGETSGKVLTCLARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQ
: .: . . . . ... .: : .: :.:. : . :: : . :... . . :
NP_000 YLEMGHDITRLFYSNIQTVINNWL-LIEGHTIGIGDSI----ADSKTYQDIQNTIKKAKQ
660 670 680 690 700 710
830 840 850 860 870 880
pF1KB3 AVRAALNLPEAASYDEVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGL
: ... : : .:. . : . :...::. :. .
NP_000 DV---IEVIEKAHNNEL-----------EPTPGNTLRQTFENQVNRILNDARDKTGSSAQ
720 730 740 750
890 900 910 920 930 940
pF1KB3 HRQFPENSLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTP
. :... :: :::::: .: :. ..:: ..::.: :. . ..:: : .. :
NP_000 KSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGP
760 770 780 790 800 810
950 960 970 980 990 1000
pF1KB3 RAGGFVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDL
.. ::: . .:.:. : ::::: :.:::::.::::::...::.:: .:: .:...:.::
NP_000 ESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDA
820 830 840 850 860 870
1010 1020 1030 1040 1050
pF1KB3 TVRDSDGSVVQFLYGEDGLDIPKTQF-----LQP------KQFPFLASNYEVIMKSQH--
:::.: ..:::. :::::: ...: :.: :.: : .: ... .. .
NP_000 TVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQED
880 890 900 910 920 930
1060 1070 1080 1090 1100 1110
pF1KB3 -LHEVLSRADPKKALHHFRAIKKWQSKHPNTLLRRGAFLSYSQKIQEAVKALKLESENR-
...::: : .. :. .... . . . : : . ..:. . :.. . .
NP_000 LVKDVLSNAHIQNELE-----REFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQK
940 950 960 970 980 990
1120 1130 1140 1150 1160
pF1KB3 ----NGRSPGTQEMLRMWYELDEESRRKYQKKAAACPDPSLSVWRPDIYFASVSETFETK
: : :. . ... . : :. : . . : :: : :.. ... .
NP_000 IFHINPRLPSDLHPIKVVEGVKELSK----KLVIVNGDDPLS--RQAQENATLLFNIHLR
1000 1010 1020 1030 1040
1170 1180 1190 1200 1210 1220
pF1KB3 VDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQM
:.. : . . : : ..: : .. :..... .::: :: :::::.:::.:::
NP_000 STLCSRRMAEEFRLSGE----AFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQM
1050 1060 1070 1080 1090 1100
1230 1240 1250 1260 1270 1280
pF1KB3 TLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLN-TKKALKRVKSLKKQL
::::::.:: . :::::.:::.:.. . : . ::: ..: .:. . . .:.:.. .:
NP_000 TLNTFHYAGVSAKNVTLGVPRLKELINI-SKKPKTPSLTVFLLGQSARDAERAKDILCRL
1110 1120 1130 1140 1150 1160
1290 1300 1310 1320 1330 1340
pF1KB3 TRVCLGEVLQKIDVQ-----ESFCMEEKQNKFQVYQLRFQFLPHAYYQQEKCLRPEDILR
.. : .: . . .: . : :. .:: .: . . :: : .
NP_000 EHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDF--DVARISPWLLRVELDRK
1170 1180 1190 1200 1210
1350 1360 1370 1380 1390 1400
pF1KB3 FMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHI
: : :: ::.: .: : :: .: . . .:.. : .
NP_000 HMTDR--KLTMEQIAEKIN--------------------AG-FGDDLNCIFNDDNAEKLV
1220 1230 1240 1250
1410 1420 1430 1440 1450 1460
pF1KB3 VDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQ
. . . :: .. ...:: :: ... : : : ::
NP_000 LRIRIMN-----SDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMT--------------
1260 1270 1280 1290
1470 1480 1490 1500 1510 1520
pF1KB3 EQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVREIHPFIDDYQYDTE
.:....:
NP_000 -----------------------------------------LQGIEQIS-----------
1300
1530 1540 1550 1560 1570 1580
pF1KB3 ESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGITRCLLNETTNNKNEKELVLNT
.: ..:: : . . ...: . : .: .:.:
NP_000 -----KVYMHLP----------------------QTDNKKKIIITEDGEFKALQEWILET
1310 1320 1330
1590 1600 1610 1620 1630 1640
pF1KB3 EGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRVIEKEIKDVFAVYGIAVDPRH
.:..: .... .: : : :::: : .. ::::. ...:.:. :.. : :. ::
NP_000 DGVSLMRVLSEKDV-DPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRH
1340 1350 1360 1370 1380 1390
1650 1660 1670 1680 1690
pF1KB3 LSLVADYMCFEGVYKPLNRFGI-RSNSSPLQQMTFETSFQFLKQATMLGSHDELRSPSAC
:.:. : : .: ..: :. :....::.. .:: . . : .:. : : ... :
NP_000 LALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSEN
1400 1410 1420 1430 1440 1450
1700 1710 1720
pF1KB3 LVVGKVVRGGTGLFELKQPLR
...:... .::: :.:
NP_000 IMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAM
1460 1470 1480 1490 1500 1510
>>NP_008986 (OMIM: 607694,614258) DNA-directed RNA polym (1390 aa)
initn: 1492 init1: 459 opt: 485 Z-score: 302.8 bits: 68.8 E(85289): 4e-10
Smith-Waterman score: 1498; 29.3% identity (55.0% similar) in 1311 aa overlap (10-1298:13-1118)
10 20 30 40 50
pF1KB3 MLISKNMPWRRLQGISFGMYSAEELKKLS-VKSITNPRY-LDSLGNPSANGLYDLAL
.... : ::: : ::... . .. ... : :. : :. : .
NP_008 MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 GPADSKEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRA
: ... . : :: .....: :: :.:.: : .. : . .:. : .: :
NP_008 GTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTC----C---
70 80 90 100 110
120 130 140 150 160 170
pF1KB3 VIHLLLCQLRVLEVGALQAVYELERILNRFLEENADPSASEIREE-LEQYTTEIVQNNLL
:..: : : .. .::. :. . .... :.. .. ..
NP_008 --HIMLSQ-------------EEKK---QFLDYLKRPGLTYLQKRGLKKKISDKCRK---
120 130 140 150
180 190 200 210 220 230
pF1KB3 GSQGAHVKNVCESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVHRT
::.:. . . . : . . ::...:: .. : :. :
NP_008 -------KNICHHCGAFNGTVKKCGLLKIIHEKYKTNKKVVDPIVSNFLQSFETAIEH--
160 170 180 190 200
240 250 260 270 280 290
pF1KB3 AGQKDSEPLGIEEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRF--
.:. ::: .:. :.:.:. : :: ::. . . . .
NP_008 --NKEVEPL------LGR--------AQENLNPL-----VVLN-LFKRIPAEDVPLLLMN
210 220 230 240
300 310 320 330 340
pF1KB3 ----NPSVFFLDFLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQE
.:: ..: :.::: :: : ..: . .. . .: . ..... .. ..
NP_008 PEAGKPSDLILTRLLVPPLCIRP-SVVSD-LKSGTNEDDLTMKLTEIIFLNDVI----KK
250 260 270 280 290
350 360 370 380 390 400
pF1KB3 QKLPEEVATPTTDEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDK
... . : ..: : : :: . . ..::..
NP_008 HRI---------SGAKTQMIMED-------------------WDFLQLQCALYINSELSG
300 310 320
410 420 430 440 450 460
pF1KB3 LMMDKYP-----GIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFA
. .. : :. : :. :.: :: .. :::::...:.:: :: . .:...:. :
NP_008 IPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPVHVA
330 340 350 360 370 380
470 480 490 500 510 520
pF1KB3 TKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLL
::.:. :. :.. ::. : :::.:::::... .. . . . . .:: .:..:
NP_008 KILTFPEKVNKANINFLRKLVQNGPEVHPGANFIQQRHTQMKRF--LKYGNREKMAQEL-
390 400 410 420 430 440
530 540 550 560 570 580
pF1KB3 TPATGAPKPQGTKIVCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCK
. :: ::. .::..:.::::.::. ::.:: ::. :. ...:.. :
NP_008 ---------KYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLARVKPH-RTFRFNECVCT
450 460 470 480 490
590 600 610 620 630 640
pF1KB3 AYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTT
::::::::::: :.::.: ..::: :: : . ..:..:.:: . ::: .... .:
NP_008 PYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIAAIQDFLTGAYLLTL
500 510 520 530 540 550
650 660 670 680 690 700
pF1KB3 RGCFFTREHYMELVYRGLT--DKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHI
. :: : . ... :. :. .:.: :.:::: ::::::. :..: : :
NP_008 KDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVTLWTGKQIFSVILR---PSDDN
560 570 580 590 600 610
710 720 730 740 750
pF1KB3 PLNLSGKAKITGKAWVKETPRSVPGFNPDSMC--ESQVIIREGELLCGVLDKAHYGS-SA
:. . ..: :: . : . : .: .: : :...::. : .::. :: :
NP_008 PVRANLRTK--GKQYC--------GKGED-LCANDSYVTIQNSELMSGSMDKGTLGSGSK
620 630 640 650 660
760 770 780 790 800 810
pF1KB3 YGLVHCCYEIYGGETSGKVLTCLARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEE
.. . . .: . .. ... :::: .::. :::..:. : : : . . . :
NP_008 NNIFYILLRDWGQNEAADAMSRLARLAPVYLS-NRGFSIGIGD--VTPGQGLLKAKY--E
670 680 690 700 710
820 830 840 850 860 870
pF1KB3 STHCGPQAVRAALNLPEAASYDEVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINK
. : . . :: . :: :. .. .. . :: :.. .. ..
NP_008 LLNAGYKKCDEYI---EALN----TGKLQQQPGCTAEETLEALILK---ELSVIRDHAGS
720 730 740 750 760
880 890 900 910 920 930
pF1KB3 ACMPFGLHRQFPE-NSLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPC
::. :.. . :: :. :.::: .: :. .:: . : : : ..:::
NP_008 ACL-----RELDKSNSPLTMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPH
770 780 790 800 810 820
940 950 960 970 980 990
pF1KB3 FEPYEFTPRAGGFVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLE
:: . : : :::.. : .:. : ::::: ::::::::::::::...::.:: ..: ::
NP_008 FEKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLE
830 840 850 860 870 880
1000 1010 1020 1030 1040 1050
pF1KB3 GLVVQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFL-QPKQFPFLASNYEVIMKSQHLHEV
: :::::::.: :...::.:: :::: . .: .: . .: ....
NP_008 DLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCP-----
890 900 910 920 930
1060 1070 1080 1090 1100 1110
pF1KB3 LSRADPKKALHHFRAIKKWQSKHPNTLLRRGAFLSYSQK-IQEAVKALKLESENRNGRSP
..: :: . . : .: ..... :: ... .:: : .:
NP_008 ---SEP--ALSKNELILTTES-----IMKKSEFLCCQDSFLQEIKKFIK-----------
940 950 960 970
1120 1130 1140 1150 1160 1170
pF1KB3 GTQEMLRMWYELDEESRRKYQKKAAACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWA
:..: .. ..: :: . . .: . .: ..: .
NP_008 GVSEKIK-------KTRDKYGINDNGTTEPRV------LY----------QLDRITP---
980 990 1000
1180 1190 1200 1210 1220 1230
pF1KB3 AQTEKSYEKSELSLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAG
.:.:: : . : :..:. ::: ::: : :::::::.:::::.::::::
NP_008 TQVEKFLETCR---D--------KYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAG
1010 1020 1030 1040 1050
1240 1250 1260 1270 1280 1290
pF1KB3 RGEMNVTLGIPRLREILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQ
. ::.:::.::..::. :: :.::.... :. .. .: .. .. :::. .
NP_008 VASMNITLGVPRIKEIIN-ASKAISTPIITAQ-LDKDDDADYARLVKGRIEKTLLGEISE
1060 1070 1080 1090 1100 1110
1300 1310 1320 1330 1340 1350
pF1KB3 KIDVQESFCMEEKQNKFQVYQLRFQFLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIK
:.
NP_008 YIEEVFLPDDCFILVKLSLERIRLLRLEVNAETVRYSICTSKLRVKPGDVAVHGEAVVCV
1120 1130 1140 1150 1160 1170
1720 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:01:12 2016 done: Tue Nov 8 11:01:14 2016
Total Scan time: 15.500 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]