Result of FASTA (omim) for
pFN21AB0472
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0472, 993 aa
1>>>pF1KB0472 993 - 993 aa - 993 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8209+/-0.000426; mu= 1.9062+/- 0.027
mean_var=235.2594+/-46.374, 0's: 0 Z-trim(119.3): 63 B-trim: 0 in 0/55
Lambda= 0.083618
statistics sampled from 33066 (33129) to 33066 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.388), width: 16
Scan time: 10.010
The best scores are: opt bits E(85289)
NP_002171 (OMIM: 600502,604320,616155) DNA-binding ( 993) 6438 790.4 0
XP_005274031 (OMIM: 600502,604320,616155) PREDICTE ( 656) 4330 535.9 2.6e-151
XP_016873159 (OMIM: 600502,604320,616155) PREDICTE ( 656) 4330 535.9 2.6e-151
XP_016873158 (OMIM: 600502,604320,616155) PREDICTE ( 656) 4330 535.9 2.6e-151
XP_005274032 (OMIM: 600502,604320,616155) PREDICTE ( 617) 3846 477.5 9.2e-134
XP_011543296 (OMIM: 600502,604320,616155) PREDICTE ( 582) 3838 476.6 1.7e-133
XP_016873160 (OMIM: 600502,604320,616155) PREDICTE ( 546) 3440 428.5 4.6e-119
XP_005274033 (OMIM: 600502,604320,616155) PREDICTE ( 540) 2596 326.7 2e-88
NP_002902 (OMIM: 601430) regulator of nonsense tra (1118) 496 73.6 6.8e-12
XP_016882595 (OMIM: 601430) PREDICTED: regulator o (1126) 496 73.6 6.8e-12
NP_001284478 (OMIM: 601430) regulator of nonsense (1129) 496 73.6 6.8e-12
XP_016882594 (OMIM: 601430) PREDICTED: regulator o (1137) 496 73.6 6.9e-12
XP_016869985 (OMIM: 602433,606002,608465) PREDICTE ( 857) 405 62.5 1.1e-08
XP_011516706 (OMIM: 602433,606002,608465) PREDICTE (2706) 405 62.8 2.8e-08
XP_005272229 (OMIM: 602433,606002,608465) PREDICTE (2706) 405 62.8 2.8e-08
XP_005272228 (OMIM: 602433,606002,608465) PREDICTE (2706) 405 62.8 2.8e-08
XP_011516707 (OMIM: 602433,606002,608465) PREDICTE (2706) 405 62.8 2.8e-08
XP_005272230 (OMIM: 602433,606002,608465) PREDICTE (2706) 405 62.8 2.8e-08
XP_016869986 (OMIM: 602433,606002,608465) PREDICTE ( 828) 384 60.0 6.2e-08
NP_055861 (OMIM: 602433,606002,608465) probable he (2677) 384 60.3 1.6e-07
XP_016869984 (OMIM: 602433,606002,608465) PREDICTE (2677) 384 60.3 1.6e-07
XP_011516708 (OMIM: 602433,606002,608465) PREDICTE (2413) 292 49.2 0.00033
NP_208384 (OMIM: 611265) helicase with zinc finger (2080) 277 47.3 0.001
NP_001032412 (OMIM: 611265) helicase with zinc fin (2649) 277 47.4 0.0012
XP_011537719 (OMIM: 601810,615156,615807) PREDICTE ( 700) 262 45.2 0.0014
XP_016871288 (OMIM: 601810,615156,615807) PREDICTE ( 836) 262 45.3 0.0017
NP_001073918 (OMIM: 601810,615156,615807) DNA repl (1060) 262 45.3 0.002
XP_006717743 (OMIM: 601810,615156,615807) PREDICTE (1090) 262 45.3 0.0021
>>NP_002171 (OMIM: 600502,604320,616155) DNA-binding pro (993 aa)
initn: 6438 init1: 6438 opt: 6438 Z-score: 4209.3 bits: 790.4 E(85289): 0
Smith-Waterman score: 6438; 99.8% identity (99.9% similar) in 993 aa overlap (1-993:1-993)
10 20 30 40 50 60
pF1KB0 MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 EIHPLTFFNTCLDTSQKEAVSFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
NP_002 EIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 TEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 YNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 VTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 HAATKPQGPAASTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGV
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HAATKPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 ESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 TVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 VRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 KCTAGVTTLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KCTAGVTTLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGS
910 920 930 940 950 960
970 980 990
pF1KB0 LDPAKRAQLQRRLDKKLSELSNQRTSRRKERGT
:::::::::::::::::::::::::::::::::
NP_002 LDPAKRAQLQRRLDKKLSELSNQRTSRRKERGT
970 980 990
>>XP_005274031 (OMIM: 600502,604320,616155) PREDICTED: D (656 aa)
initn: 4330 init1: 4330 opt: 4330 Z-score: 2837.6 bits: 535.9 E(85289): 2.6e-151
Smith-Waterman score: 4330; 99.8% identity (100.0% similar) in 656 aa overlap (338-993:1-656)
310 320 330 340 350 360
pF1KB0 KKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGPLKLLPES
::::::::::::::::::::::::::::::
XP_005 MLESLTSANVVLATNTGASADGPLKLLPES
10 20 30
370 380 390 400 410 420
pF1KB0 YFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLA
40 50 60 70 80 90
430 440 450 460 470 480
pF1KB0 EEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVP
100 110 120 130 140 150
490 500 510 520 530 540
pF1KB0 LLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDL
160 170 180 190 200 210
550 560 570 580 590 600
pF1KB0 LRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRH
220 230 240 250 260 270
610 620 630 640 650 660
pF1KB0 VAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQ
280 290 300 310 320 330
670 680 690 700 710 720
pF1KB0 GPAASTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVD
340 350 360 370 380 390
730 740 750 760 770 780
pF1KB0 HFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAP
400 410 420 430 440 450
790 800 810 820 830 840
pF1KB0 RPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQ
460 470 480 490 500 510
850 860 870 880 890 900
pF1KB0 PASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVT
520 530 540 550 560 570
910 920 930 940 950 960
pF1KB0 TLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLDPAKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLDPAKRA
580 590 600 610 620 630
970 980 990
pF1KB0 QLQRRLDKKLSELSNQRTSRRKERGT
::::::::::::::::::::::::::
XP_005 QLQRRLDKKLSELSNQRTSRRKERGT
640 650
>>XP_016873159 (OMIM: 600502,604320,616155) PREDICTED: D (656 aa)
initn: 4330 init1: 4330 opt: 4330 Z-score: 2837.6 bits: 535.9 E(85289): 2.6e-151
Smith-Waterman score: 4330; 99.8% identity (100.0% similar) in 656 aa overlap (338-993:1-656)
310 320 330 340 350 360
pF1KB0 KKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGPLKLLPES
::::::::::::::::::::::::::::::
XP_016 MLESLTSANVVLATNTGASADGPLKLLPES
10 20 30
370 380 390 400 410 420
pF1KB0 YFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLA
40 50 60 70 80 90
430 440 450 460 470 480
pF1KB0 EEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVP
100 110 120 130 140 150
490 500 510 520 530 540
pF1KB0 LLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDL
160 170 180 190 200 210
550 560 570 580 590 600
pF1KB0 LRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRH
220 230 240 250 260 270
610 620 630 640 650 660
pF1KB0 VAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQ
280 290 300 310 320 330
670 680 690 700 710 720
pF1KB0 GPAASTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVD
340 350 360 370 380 390
730 740 750 760 770 780
pF1KB0 HFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAP
400 410 420 430 440 450
790 800 810 820 830 840
pF1KB0 RPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQ
460 470 480 490 500 510
850 860 870 880 890 900
pF1KB0 PASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVT
520 530 540 550 560 570
910 920 930 940 950 960
pF1KB0 TLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLDPAKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLDPAKRA
580 590 600 610 620 630
970 980 990
pF1KB0 QLQRRLDKKLSELSNQRTSRRKERGT
::::::::::::::::::::::::::
XP_016 QLQRRLDKKLSELSNQRTSRRKERGT
640 650
>>XP_016873158 (OMIM: 600502,604320,616155) PREDICTED: D (656 aa)
initn: 4330 init1: 4330 opt: 4330 Z-score: 2837.6 bits: 535.9 E(85289): 2.6e-151
Smith-Waterman score: 4330; 99.8% identity (100.0% similar) in 656 aa overlap (338-993:1-656)
310 320 330 340 350 360
pF1KB0 KKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGPLKLLPES
::::::::::::::::::::::::::::::
XP_016 MLESLTSANVVLATNTGASADGPLKLLPES
10 20 30
370 380 390 400 410 420
pF1KB0 YFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLA
40 50 60 70 80 90
430 440 450 460 470 480
pF1KB0 EEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVP
100 110 120 130 140 150
490 500 510 520 530 540
pF1KB0 LLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDL
160 170 180 190 200 210
550 560 570 580 590 600
pF1KB0 LRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRH
220 230 240 250 260 270
610 620 630 640 650 660
pF1KB0 VAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQ
280 290 300 310 320 330
670 680 690 700 710 720
pF1KB0 GPAASTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVD
340 350 360 370 380 390
730 740 750 760 770 780
pF1KB0 HFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAP
400 410 420 430 440 450
790 800 810 820 830 840
pF1KB0 RPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQ
460 470 480 490 500 510
850 860 870 880 890 900
pF1KB0 PASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVT
520 530 540 550 560 570
910 920 930 940 950 960
pF1KB0 TLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLDPAKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLDPAKRA
580 590 600 610 620 630
970 980 990
pF1KB0 QLQRRLDKKLSELSNQRTSRRKERGT
::::::::::::::::::::::::::
XP_016 QLQRRLDKKLSELSNQRTSRRKERGT
640 650
>>XP_005274032 (OMIM: 600502,604320,616155) PREDICTED: D (617 aa)
initn: 3838 init1: 3838 opt: 3846 Z-score: 2522.5 bits: 477.5 E(85289): 9.2e-134
Smith-Waterman score: 3846; 97.0% identity (98.3% similar) in 601 aa overlap (393-993:18-617)
370 380 390 400 410 420
pF1KB0 LLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSL
..: . . :. . :. ::::::::::
XP_005 MNSELSLFSEDRKKMCKKSCRVESHHRGVGSPGVGG-AALAGLSLSL
10 20 30 40
430 440 450 460 470 480
pF1KB0 MERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATE
50 60 70 80 90 100
490 500 510 520 530 540
pF1KB0 ETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYN
110 120 130 140 150 160
550 560 570 580 590 600
pF1KB0 LQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVT
170 180 190 200 210 220
610 620 630 640 650 660
pF1KB0 RARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHA
230 240 250 260 270 280
670 680 690 700 710 720
pF1KB0 ATKPQGPAASTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVES
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATKPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVES
290 300 310 320 330 340
730 740 750 760 770 780
pF1KB0 QDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITV
350 360 370 380 390 400
790 800 810 820 830 840
pF1KB0 SKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVR
410 420 430 440 450 460
850 860 870 880 890 900
pF1KB0 SAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKC
470 480 490 500 510 520
910 920 930 940 950 960
pF1KB0 TAGVTTLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAGVTTLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLD
530 540 550 560 570 580
970 980 990
pF1KB0 PAKRAQLQRRLDKKLSELSNQRTSRRKERGT
:::::::::::::::::::::::::::::::
XP_005 PAKRAQLQRRLDKKLSELSNQRTSRRKERGT
590 600 610
>>XP_011543296 (OMIM: 600502,604320,616155) PREDICTED: D (582 aa)
initn: 3838 init1: 3838 opt: 3838 Z-score: 2517.6 bits: 476.6 E(85289): 1.7e-133
Smith-Waterman score: 3838; 99.8% identity (100.0% similar) in 581 aa overlap (413-993:2-582)
390 400 410 420 430 440
pF1KB0 ASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQY
::::::::::::::::::::::::::::::
XP_011 MAALAGLSLSLMERLAEEYGARVVRTLTVQY
10 20 30
450 460 470 480 490 500
pF1KB0 RMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGCGLFELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGCGLFELE
40 50 60 70 80 90
510 520 530 540 550 560
pF1KB0 EEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHPELEIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHPELEIK
100 110 120 130 140 150
570 580 590 600 610 620
pF1KB0 SVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAF
160 170 180 190 200 210
630 640 650 660 670 680
pF1KB0 LKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQGPAASTRTGSQRQEG
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_011 LKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQGPATSTRTGSQRQEG
220 230 240 250 260 270
690 700 710 720 730 740
pF1KB0 GQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVDHFRAMIVEFMASKKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVDHFRAMIVEFMASKKM
280 290 300 310 320 330
750 760 770 780 790 800
pF1KB0 QLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAPRPRAALGPPAGTGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAPRPRAALGPPAGTGGP
340 350 360 370 380 390
810 820 830 840 850 860
pF1KB0 APLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQPASKEQQASGQQKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQPASKEQQASGQQKLP
400 410 420 430 440 450
870 880 890 900 910 920
pF1KB0 EKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVTTLGQFCQLCSRRYCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVTTLGQFCQLCSRRYCL
460 470 480 490 500 510
930 940 950 960 970 980
pF1KB0 SHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLDPAKRAQLQRRLDKKLSELSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLDPAKRAQLQRRLDKKLSELSN
520 530 540 550 560 570
990
pF1KB0 QRTSRRKERGT
:::::::::::
XP_011 QRTSRRKERGT
580
>>XP_016873160 (OMIM: 600502,604320,616155) PREDICTED: D (546 aa)
initn: 3440 init1: 3440 opt: 3440 Z-score: 2258.5 bits: 428.5 E(85289): 4.6e-119
Smith-Waterman score: 3440; 99.8% identity (99.8% similar) in 544 aa overlap (1-544:1-544)
10 20 30 40 50 60
pF1KB0 MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 EIHPLTFFNTCLDTSQKEAVSFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_016 EIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 TEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 YNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVA
::::
XP_016 YNLQAP
>>XP_005274033 (OMIM: 600502,604320,616155) PREDICTED: D (540 aa)
initn: 2623 init1: 2596 opt: 2596 Z-score: 1708.4 bits: 326.7 E(85289): 2e-88
Smith-Waterman score: 2596; 98.1% identity (98.6% similar) in 420 aa overlap (1-420:1-420)
10 20 30 40 50 60
pF1KB0 MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 EIHPLTFFNTCLDTSQKEAVSFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_005 EIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSL
:::::::::::::::::::::::::::::::::::::::::::::::::::. . ::
XP_005 LKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHNLQSVDTSL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAA
XP_005 DGGHWAETQQTMVLPCGDTGALMQWPGPGCPGGDTGVLMRWPGPGCPGGDTGALMQWPGP
430 440 450 460 470 480
>>NP_002902 (OMIM: 601430) regulator of nonsense transcr (1118 aa)
initn: 382 init1: 221 opt: 496 Z-score: 334.6 bits: 73.6 E(85289): 6.8e-12
Smith-Waterman score: 690; 29.8% identity (58.8% similar) in 638 aa overlap (17-633:312-895)
10 20 30 40
pF1KB0 MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKE---LQSR
:: . : ...: .. :.::... :...
NP_002 KPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQT-QDNITVRWDLGLNKK
290 300 310 320 330 340
50 60 70 80 90 100
pF1KB0 GVCLLKL-QVSSQRTGLYGRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLA
. . : ...:. . : . : :. : : .. : .. . : : :...:
NP_002 RIAYFTLPKTDSDMRLMQGDEICL---RYKGDLAPLWKGI---GHVIKVPD--NYGDEIA
350 360 370 380 390
110 120 130 140 150 160
pF1KB0 TGILTRVTQKSVTVAFDESHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGP
. ..:: . . .:.::... . ..... :...:: .. ...
NP_002 IEL-----RSSVGAPVEVTHNFQVDF----------VWKSTSFDRMQSALKTFAVDETSV
400 410 420 430
170 180 190 200 210
pF1KB0 ASSLIEVLFGRSAPSPASEIH-PLTFFNTCL---DTSQKEAVSFALSQKELAIIHGPPGT
.. . . :.:. . . . . : : : . :: ::. .: :. :..:.:::::
NP_002 SGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVL-QRPLSLIQGPPGT
440 450 460 470 480 490
220 230 240 250 260 270
pF1KB0 GKTTTVVEIILQAVKQGL-KVLCCAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQ
:::.: . :. . ..:: :: :::::::::.:.:.. ...:: .: :.:.
NP_002 GKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSR--EAID-
500 510 520 530 540 550
280 290 300 310 320 330
pF1KB0 HSLDAVLARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAA
: . :: . :: ...:.. .: : : : ... . . . ::. :
NP_002 -SPVSFLALHN--QI-----RNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAER-
560 570 580 590 600
340 350 360 370 380 390
pF1KB0 MLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPL-LKARKCI
: : .:.:. : .:: : .: . : ..::: .:: : : .:. : :.. :
NP_002 --ELLMNADVICCTCVGA---GDPRL-AKMQFRSILIDESTQATEPECMVPVVLGAKQLI
610 620 630 640 650
400 410 420 430 440 450
pF1KB0 LAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTM
:.::: :: :... .::: :::: ::.:::. : : .: : :::::: :. . :. .
NP_002 LVGDHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIR-LQVQYRMHPALSAFPSNIF
660 670 680 690 700 710
460 470 480 490 500 510
pF1KB0 YLGQLTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVR
: :.: ..: .. . . . :... : : .:. :.:. :
NP_002 YEGSLQNGVTAADRVKKGFD--FQWPQPDKPMFFYVTQG-------QEEIASSGTSYLNR
720 730 740 750 760
520 530 540 550 560
pF1KB0 LVSLHIQA----LVDAGVPARDIAVVSPYNLQVDLLRQSL-----VHR--HPELEIKSVD
. ... :. ::. .:....::. : . : : . .: . :.:: :::
NP_002 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD
770 780 790 800 810 820
570 580 590 600 610 620
pF1KB0 GFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKT
.::::::. .::: ::.:.. .::: . ::.:::.:::: : .. . ...... . .
NP_002 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH
830 840 850 860 870 880
630 640 650 660 670 680
pF1KB0 LVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQGPAASTRTGSQRQEGGQE
:..:. ..
NP_002 LLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVY
890 900 910 920 930 940
>>XP_016882595 (OMIM: 601430) PREDICTED: regulator of no (1126 aa)
initn: 382 init1: 221 opt: 496 Z-score: 334.5 bits: 73.6 E(85289): 6.8e-12
Smith-Waterman score: 695; 29.7% identity (58.4% similar) in 639 aa overlap (17-633:312-903)
10 20 30 40
pF1KB0 MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKE---LQSR
:: . : ...: .. :.::... :...
XP_016 KPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQT-QDNITVRWDLGLNKK
290 300 310 320 330 340
50 60 70 80 90 100
pF1KB0 GVCLLKL-QVSSQRTGLYGRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLA
. . : ...:. . : . : :. : : .. : .. . : :: ..
XP_016 RIAYFTLPKTDSDMRLMQGDEICL---RYKGDLAPLWKGI---GHVIKVPDNANLTQHTD
350 360 370 380 390
110 120 130 140 150 160
pF1KB0 TGILTRVTQKS-VTVAFDESHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSG
: . .: : . . .:.::... . ..... :...:: .. ...
XP_016 YGDEIAIELRSSVGAPVEVTHNFQVDF----------VWKSTSFDRMQSALKTFAVDETS
400 410 420 430 440
170 180 190 200 210
pF1KB0 PASSLIEVLFGRSAPSPASEIH-PLTFFNTCL---DTSQKEAVSFALSQKELAIIHGPPG
.. . . :.:. . . . . : : : . :: ::. .: :. :..:.::::
XP_016 VSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVL-QRPLSLIQGPPG
450 460 470 480 490 500
220 230 240 250 260 270
pF1KB0 TGKTTTVVEIILQAVKQGL-KVLCCAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQ
::::.: . :. . ..:: :: :::::::::.:.:.. ...:: .: :.:.
XP_016 TGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSR--EAID
510 520 530 540 550 560
280 290 300 310 320 330
pF1KB0 QHSLDAVLARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEA
: . :: . :: ...:.. .: : : : ... . . . ::. :
XP_016 --SPVSFLALHN--QI-----RNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAER
570 580 590 600 610
340 350 360 370 380 390
pF1KB0 AMLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPL-LKARKC
: : .:.:. : .:: : .: . : ..::: .:: : : .:. : :..
XP_016 ---ELLMNADVICCTCVGA---GDPRL-AKMQFRSILIDESTQATEPECMVPVVLGAKQL
620 630 640 650 660
400 410 420 430 440 450
pF1KB0 ILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDT
::.::: :: :... .::: :::: ::.:::. : : .: : :::::: :. . :.
XP_016 ILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIR-LQVQYRMHPALSAFPSNI
670 680 690 700 710 720
460 470 480 490 500 510
pF1KB0 MYLGQLTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEV
.: :.: ..: .. . . . :... : : .:. :.:.
XP_016 FYEGSLQNGVTAADRVKKGFD--FQWPQPDKPMFFYVTQG-------QEEIASSGTSYLN
730 740 750 760 770
520 530 540 550 560
pF1KB0 RLVSLHIQA----LVDAGVPARDIAVVSPYNLQVDLLRQSL-----VHR--HPELEIKSV
: . ... :. ::. .:....::. : . : : . .: . :.:: ::
XP_016 RTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASV
780 790 800 810 820 830
570 580 590 600 610 620
pF1KB0 DGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLK
:.::::::. .::: ::.:.. .::: . ::.:::.:::: : .. . ...... . .
XP_016 DAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWN
840 850 860 870 880 890
630 640 650 660 670 680
pF1KB0 TLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQGPAASTRTGSQRQEGGQ
:..:. ..
XP_016 HLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSV
900 910 920 930 940 950
993 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:50:16 2016 done: Mon Nov 7 18:50:17 2016
Total Scan time: 10.010 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]