Result of FASTA (omim) for
pFN21AB0412
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0412, 824 aa
1>>>pF1KB0412 824 - 824 aa - 824 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8999+/-0.000396; mu= 7.9320+/- 0.025
mean_var=128.0277+/-25.514, 0's: 0 Z-trim(115.2): 135 B-trim: 323 in 1/54
Lambda= 0.113350
statistics sampled from 25309 (25446) to 25309 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.298), width: 16
Scan time: 11.520
The best scores are: opt bits E(85289)
NP_009135 (OMIM: 606168) probable ATP-dependent RN ( 824) 5448 902.9 0
NP_001958 (OMIM: 601102) eukaryotic initiation fac ( 407) 834 148.3 6.7e-35
NP_001407 (OMIM: 602641) eukaryotic initiation fac ( 406) 825 146.8 1.9e-34
NP_055555 (OMIM: 268305,608546) eukaryotic initiat ( 411) 798 142.4 4e-33
NP_542165 (OMIM: 142560) spliceosome RNA helicase ( 428) 782 139.8 2.5e-32
NP_004631 (OMIM: 142560) spliceosome RNA helicase ( 428) 782 139.8 2.5e-32
NP_009173 (OMIM: 605812) ATP-dependent RNA helicas ( 479) 679 122.9 3.3e-27
XP_011521136 (OMIM: 605812) PREDICTED: ATP-depende ( 484) 679 122.9 3.3e-27
XP_011521134 (OMIM: 605812) PREDICTED: ATP-depende ( 539) 679 123.0 3.7e-27
NP_001191439 (OMIM: 602641) eukaryotic initiation ( 347) 653 118.6 4.7e-26
NP_001244103 (OMIM: 605812) ATP-dependent RNA heli ( 370) 643 117.0 1.6e-25
XP_016878379 (OMIM: 605812) PREDICTED: ATP-depende ( 370) 643 117.0 1.6e-25
XP_006721190 (OMIM: 605812) PREDICTED: ATP-depende ( 370) 643 117.0 1.6e-25
NP_001244102 (OMIM: 605812) ATP-dependent RNA heli ( 370) 643 117.0 1.6e-25
NP_001014449 (OMIM: 605812) ATP-dependent RNA heli ( 370) 643 117.0 1.6e-25
XP_011541093 (OMIM: 607663) PREDICTED: ATP-depende ( 482) 620 113.3 2.7e-24
NP_037396 (OMIM: 607663) ATP-dependent RNA helicas ( 483) 620 113.3 2.7e-24
XP_011541092 (OMIM: 607663) PREDICTED: ATP-depende ( 486) 620 113.3 2.7e-24
NP_060365 (OMIM: 616621) probable ATP-dependent RN ( 796) 613 112.2 9.3e-24
NP_001014451 (OMIM: 605812) ATP-dependent RNA heli ( 448) 603 110.5 1.7e-23
NP_001244101 (OMIM: 605812) ATP-dependent RNA heli ( 453) 603 110.5 1.7e-23
XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439) 602 110.3 1.9e-23
XP_011521135 (OMIM: 605812) PREDICTED: ATP-depende ( 508) 603 110.5 1.9e-23
XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529) 602 110.4 2.2e-23
XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529) 602 110.4 2.2e-23
XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604) 602 110.4 2.5e-23
NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648) 602 110.4 2.7e-23
NP_001317367 (OMIM: 607663) ATP-dependent RNA heli ( 369) 581 106.9 1.7e-22
NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455) 579 106.6 2.6e-22
XP_011523824 (OMIM: 268305,608546) PREDICTED: euka ( 390) 557 103.0 2.8e-21
NP_006377 (OMIM: 608469) probable ATP-dependent RN ( 729) 552 102.2 8.6e-21
NP_001091974 (OMIM: 608469) probable ATP-dependent ( 731) 552 102.2 8.6e-21
NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619) 548 101.6 1.2e-20
XP_016857920 (OMIM: 174300,615464) PREDICTED: prob ( 619) 548 101.6 1.2e-20
XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619) 548 101.6 1.2e-20
XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619) 548 101.6 1.2e-20
NP_001244104 (OMIM: 605812) ATP-dependent RNA heli ( 328) 539 100.0 1.8e-20
NP_076977 (OMIM: 611665) ATP-dependent RNA helicas ( 881) 545 101.1 2.3e-20
NP_001104792 (OMIM: 611665) ATP-dependent RNA heli ( 882) 545 101.1 2.3e-20
NP_001243839 (OMIM: 606357) nucleolar RNA helicase ( 715) 526 98.0 1.6e-19
NP_004719 (OMIM: 606357) nucleolar RNA helicase 2 ( 783) 526 98.0 1.8e-19
NP_001307524 (OMIM: 180630) probable ATP-dependent ( 614) 510 95.3 8.6e-19
NP_001307526 (OMIM: 180630) probable ATP-dependent ( 614) 510 95.3 8.6e-19
NP_004387 (OMIM: 180630) probable ATP-dependent RN ( 614) 510 95.3 8.6e-19
NP_001307525 (OMIM: 180630) probable ATP-dependent ( 614) 510 95.3 8.6e-19
NP_001307110 (OMIM: 174300,615464) probable ATP-de ( 567) 491 92.2 6.9e-18
XP_006711625 (OMIM: 174300,615464) PREDICTED: prob ( 557) 489 91.9 8.6e-18
NP_001160006 (OMIM: 605281) probable ATP-dependent ( 575) 487 91.6 1.1e-17
XP_011541799 (OMIM: 605281) PREDICTED: probable AT ( 678) 487 91.6 1.3e-17
NP_001136021 (OMIM: 605281) probable ATP-dependent ( 690) 487 91.6 1.3e-17
>>NP_009135 (OMIM: 606168) probable ATP-dependent RNA he (824 aa)
initn: 5448 init1: 5448 opt: 5448 Z-score: 4820.4 bits: 902.9 E(85289): 0
Smith-Waterman score: 5448; 99.8% identity (99.8% similar) in 824 aa overlap (1-824:1-824)
10 20 30 40 50 60
pF1KB0 MAAAFEASGALAAVATAMPAEHVAVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MAAAFEASGALAAVATAMPAEHVAVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 CHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 CHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQML
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 AVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 AVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 RVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 MMMRIAQKCNINLLPLPDPIPSGLMEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MMMRIAQKCNINLLPLPDPIPSGLMEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 RTLQIQKAHGDHMASSRNNSVSGLSVKSKNNTKQKLPVKSHSECGIIEKATSPKELGCDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RTLQIQKAHGDHMASSRNNSVSGLSVKSKNNTKQKLPVKSHSECGIIEKATSPKELGCDR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QSEEQMKNSVQTPVENSTNSQHQVKEALPVSLPQIPCLSSFKIHQPYTLTFAELVEDYEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QSEEQMKNSVQTPVENSTNSQHQVKEALPVSLPQIPCLSSFKIHQPYTLTFAELVEDYEH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 YIKEGLEKPVEIIRHYTGPGDQTVNPQNGFVRNKVTEQRVPVLASSSQSGDSESDSDSYS
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_009 YIKEGLEKPVEIIRHYTGPGDQTVNPQNGFVRNKVIEQRVPVLASSSQSGDSESDSDSYS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 SRTSSQSKGNKSYLEGSSDNQLKDSESTPVDDRISLEQPPNGSDTPNPEKYQESPGIQMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SRTSSQSKGNKSYLEGSSDNQLKDSESTPVDDRISLEQPPNGSDTPNPEKYQESPGIQMK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 TRLKEGASQRAKQSRRNLPRRSSFRLQTGAQEDDWYDCHREIRLSFSDTYQDYEEYWRAY
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
NP_009 TRLKEGASQRAKQSRRNLPRRSSFRLQTEAQEDDWYDCHREIRLSFSDTYQDYEEYWRAY
730 740 750 760 770 780
790 800 810 820
pF1KB0 YRAWQEYYAAASHSYYWNAQRHPSWMAAYHMNTIYLQEMMHSNQ
::::::::::::::::::::::::::::::::::::::::::::
NP_009 YRAWQEYYAAASHSYYWNAQRHPSWMAAYHMNTIYLQEMMHSNQ
790 800 810 820
>>NP_001958 (OMIM: 601102) eukaryotic initiation factor (407 aa)
initn: 640 init1: 270 opt: 834 Z-score: 747.5 bits: 148.3 E(85289): 6.7e-35
Smith-Waterman score: 835; 38.7% identity (70.3% similar) in 364 aa overlap (63-424:34-386)
40 50 60 70 80 90
pF1KB0 TPGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKA
.:... :.. .:.:. : :::.:: .: .:
NP_001 GSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRA
10 20 30 40 50 60
100 110 120 130 140 150
pF1KB0 IPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITA
: : :.:.::.:::::: .:. :..: .: :: :.::::::.: ::..:: :
NP_001 IIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILA
70 80 90 100 110 120
160 170 180 190 200 210
pF1KB0 IGIKMEGLECHVFIGGTPLSQDKTRLKKC--HIAVGSPGRIKQLIELDYLNPGSIRLFIL
.: : : ::. :::: . .. .:. ::.::.:::. .... ::.: :..:.:
NP_001 LGDYM-GATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVL
130 140 150 160 170 180
220 230 240 250 260 270
pF1KB0 DEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSD
::::..: .: :..:: :...: .: :.. .:::.: . .. :.:::: . ... .
NP_001 DEADEMLSRG-FKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEE
190 200 210 220 230 240
280 290 300 310 320 330
pF1KB0 PSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILS
.: :.::.: :. : : . : .:. . ..::..: : . ... :.. .
NP_001 LTLEGIKQFYINVERE-------EWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMH
250 260 270 280 290
340 350 360 370 380 390
pF1KB0 SKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDW
.. : . . :.:.:..: : ... ::::.::: .::::...:.::.: :.: .
NP_001 ARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR
300 310 320 330 340 350
400 410 420 430 440 450
pF1KB0 ETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCNINLLPLPDPIPSGLMEECVD
:.:.:::::.:::: :..... ::.. ..:
NP_001 ENYIHRIGRGGRFGRKGVAINFVT--EEDKRILRDIETFYNTTVEEMPMNVADLI
360 370 380 390 400
460 470 480 490 500 510
pF1KB0 WDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNNSVSGLSVKSKN
>>NP_001407 (OMIM: 602641) eukaryotic initiation factor (406 aa)
initn: 460 init1: 264 opt: 825 Z-score: 739.6 bits: 146.8 E(85289): 1.9e-34
Smith-Waterman score: 826; 37.6% identity (69.3% similar) in 378 aa overlap (64-437:34-399)
40 50 60 70 80 90
pF1KB0 PGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAI
:... ::. .:.:. : :::.:: .: .::
NP_001 SQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAI
10 20 30 40 50 60
100 110 120 130 140 150
pF1KB0 -PLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITA
: . : :.:.::.:::::: .:. :... :. .:: :.::::::.: ::..:. :
NP_001 LPCIK-GYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMA
70 80 90 100 110 120
160 170 180 190 200 210
pF1KB0 IGIKMEGLECHVFIGGTPLSQD--KTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFIL
.: : : ::. :::: . . : ... :: ::.:::. .... ::.: :..:.:
NP_001 LGDYM-GASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVL
130 140 150 160 170 180
220 230 240 250 260 270
pF1KB0 DEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSD
::::..: .: :..:: :...: .. :.. .:::.: . .. :.:::: . ... .
NP_001 DEADEMLSRG-FKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE
190 200 210 220 230 240
280 290 300 310 320 330
pF1KB0 PSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILS
.: :..:.: :. : : . : .:. . ..::..: : . ... :.. .
NP_001 LTLEGIRQFYINVERE-------EWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH
250 260 270 280 290
340 350 360 370 380 390
pF1KB0 SKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDW
.. : . . :.:.:..: : ... ::::.::: .::::...:.::.: :.: .
NP_001 ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR
300 310 320 330 340 350
400 410 420 430 440
pF1KB0 ETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMR-IAQKCNINLLPLPDPIPSGLMEECV
:.:.:::::.:::: :..... ::.. .: : : .. .:
NP_001 ENYIHRIGRGGRFGRKGVAINMVT--EEDKRTLRDIETFYNTSIEEMPLNVADLI
360 370 380 390 400
450 460 470 480 490 500
pF1KB0 DWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNNSVSGLSVKSK
>>NP_055555 (OMIM: 268305,608546) eukaryotic initiation (411 aa)
initn: 515 init1: 332 opt: 798 Z-score: 715.7 bits: 142.4 E(85289): 4e-33
Smith-Waterman score: 804; 34.2% identity (68.6% similar) in 401 aa overlap (38-437:16-404)
10 20 30 40 50 60
pF1KB0 SGALAAVATAMPAEHVAVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAEPADFESL
:.:. .:... . .:.. . . :. :...
NP_055 MATTATMATSGSARKRLLKE-EDMTKVEFETSEEVDVTPT-FDTM
10 20 30 40
70 80 90 100 110 120
pF1KB0 LLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLE
: . .:.:. : :::.:: .: .:: : :.:.:..:::::: .:: .:. : ..
NP_055 GLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQ
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB0 NLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKC-HIAVG
:: ::::::::.::::.. . :.: :. ..::. :::: ...: .: :...:
NP_055 VRETQALILAPTRELAVQIQKGLLALGDYMN-VQCHACIGGTNVGEDIRKLDYGQHVVAG
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB0 SPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATY
.:::. ..:. : .:....:::::..:..: :.::: .: :: . :.. .:::
NP_055 TPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKG-FKEQIYDVYRYLPPATQVVLISATL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB0 PEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSR
:. . . .:.: :: . .. .. .: :.::.. .:. : : . : .:..
NP_055 PHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVERE-------EWKFDTLCDLYDT
230 240 250 260 270
310 320 330 340 350 360
pF1KB0 IPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLIST
. ..::..: : . ... :.. . .: . . :.: :..: . : ... ::::::
NP_055 LTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIST
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB0 DLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIA
:. .::.:. .:.:..: :.: . : :.:::::.::.: :..... .... .. :
NP_055 DVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV-KNDDIRILRDIE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB0 QKCNINLLPLPDPIPSGLMEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQ
: . .. .:
NP_055 QYYSTQIDEMPMNVADLI
400 410
>>NP_542165 (OMIM: 142560) spliceosome RNA helicase DDX3 (428 aa)
initn: 793 init1: 366 opt: 782 Z-score: 701.2 bits: 139.8 E(85289): 2.5e-32
Smith-Waterman score: 782; 35.2% identity (66.8% similar) in 398 aa overlap (54-447:37-426)
30 40 50 60 70 80
pF1KB0 AVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFE
:. . . . :...::. .:... :::
NP_542 DNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFE
10 20 30 40 50 60
90 100 110 120 130 140
pF1KB0 RPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIA
.:: :: . :: . :.:.. ::::: ::: :: .:..: . ....:.. :::.:
NP_542 HPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELA
70 80 90 100 110 120
150 160 170 180 190 200
pF1KB0 VQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKK-C-HIAVGSPGRIKQLIELDYLN
:: . .. : ... ::.:: ...:. ::: : ::.::.:::: : . ::
NP_542 FQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLN
130 140 150 160 170 180
210 220 230 240 250 260
pF1KB0 PGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDP
:. ::::: ::.::. ....... :. : ::.. ::: . . . :.:.::
NP_542 LKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDP
190 200 210 220 230 240
270 280 290 300 310 320
pF1KB0 TFVRLNSSDP-SLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHS
. ... .: ::.::: ... .::...: .:.. . :::...: . .
NP_542 MEIFVDDETKLTLHGLQQYYVKLKD--------NEKNRKLFDLLDVLEFNQVVIFVKSVQ
250 260 270 280 290
330 340 350 360 370 380
pF1KB0 RAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNL
: ::..: ..::: : .: :..::. . ..: :. :.:..:.: .::.: :.::.
NP_542 RCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNI
300 310 320 330 340 350
390 400 410 420 430 440
pF1KB0 VVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCNINLLPLPDPI
. : :.: : .::.::..::::::: ::..:. .. ... . .. ..:. ::: :
NP_542 AFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEI
360 370 380 390 400 410
450 460 470 480 490
pF1KB0 P-SGLMEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNN
:. .:.
NP_542 DISSYIEQTR
420
>>NP_004631 (OMIM: 142560) spliceosome RNA helicase DDX3 (428 aa)
initn: 793 init1: 366 opt: 782 Z-score: 701.2 bits: 139.8 E(85289): 2.5e-32
Smith-Waterman score: 782; 35.2% identity (66.8% similar) in 398 aa overlap (54-447:37-426)
30 40 50 60 70 80
pF1KB0 AVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFE
:. . . . :...::. .:... :::
NP_004 DNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFE
10 20 30 40 50 60
90 100 110 120 130 140
pF1KB0 RPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIA
.:: :: . :: . :.:.. ::::: ::: :: .:..: . ....:.. :::.:
NP_004 HPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELA
70 80 90 100 110 120
150 160 170 180 190 200
pF1KB0 VQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKK-C-HIAVGSPGRIKQLIELDYLN
:: . .. : ... ::.:: ...:. ::: : ::.::.:::: : . ::
NP_004 FQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLN
130 140 150 160 170 180
210 220 230 240 250 260
pF1KB0 PGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDP
:. ::::: ::.::. ....... :. : ::.. ::: . . . :.:.::
NP_004 LKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDP
190 200 210 220 230 240
270 280 290 300 310 320
pF1KB0 TFVRLNSSDP-SLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHS
. ... .: ::.::: ... .::...: .:.. . :::...: . .
NP_004 MEIFVDDETKLTLHGLQQYYVKLKD--------NEKNRKLFDLLDVLEFNQVVIFVKSVQ
250 260 270 280 290
330 340 350 360 370 380
pF1KB0 RAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNL
: ::..: ..::: : .: :..::. . ..: :. :.:..:.: .::.: :.::.
NP_004 RCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNI
300 310 320 330 340 350
390 400 410 420 430 440
pF1KB0 VVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCNINLLPLPDPI
. : :.: : .::.::..::::::: ::..:. .. ... . .. ..:. ::: :
NP_004 AFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEI
360 370 380 390 400 410
450 460 470 480 490
pF1KB0 P-SGLMEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNN
:. .:.
NP_004 DISSYIEQTR
420
>>NP_009173 (OMIM: 605812) ATP-dependent RNA helicase DD (479 aa)
initn: 644 init1: 215 opt: 679 Z-score: 609.4 bits: 122.9 E(85289): 3.3e-27
Smith-Waterman score: 679; 34.3% identity (64.6% similar) in 376 aa overlap (64-430:94-460)
40 50 60 70 80 90
pF1KB0 PGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAI
:: : :. .:.:. : ::.::: .: .:.
NP_009 KLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENAL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB0 PL--GRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVIT
:: .. .::.:..:::::: .: :... : : : :.:: :.:.: .::
NP_009 PLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB0 AIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLI-ELDYLNPGSIRLFIL
.: . :. . :. : . . .... .:..:.:: . . .: ...: .:..:.:
NP_009 QMGKFYPELKLAYAVRGNKLERGQ-KISE-QIVIGTPGTVLDWCSKLKFIDPKKIKVFVL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB0 DEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSD
:::: .. . :.: : :: . ::: :::. . . . : . ::. ..:. .
NP_009 DEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREE
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB0 PSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILS
.: .:::: . .: .:: : : .:.. : . ::..: . .. :. :: ::
NP_009 ETLDTIKQYYVLCSSR-------DEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELS
310 320 330 340 350
340 350 360 370 380 390
pF1KB0 SKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDW
..: . .::.: .:: .. .... . .::..:.. .::::.:.:..:.:.:.:.:
NP_009 KEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDK
360 370 380 390 400 410
400 410 420 430 440
pF1KB0 ------ETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCNINLLPLPDPIPSGL
:::.:::::.:::: ::.:.. . :.. :: .. :
NP_009 DGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEI
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB0 MEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNNSVSGL
NP_009 EKIAN
>>XP_011521136 (OMIM: 605812) PREDICTED: ATP-dependent R (484 aa)
initn: 644 init1: 215 opt: 679 Z-score: 609.3 bits: 122.9 E(85289): 3.3e-27
Smith-Waterman score: 679; 34.3% identity (64.6% similar) in 376 aa overlap (64-430:99-465)
40 50 60 70 80 90
pF1KB0 PGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAI
:: : :. .:.:. : ::.::: .: .:.
XP_011 KLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENAL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB0 PL--GRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVIT
:: .. .::.:..:::::: .: :... : : : :.:: :.:.: .::
XP_011 PLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB0 AIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLI-ELDYLNPGSIRLFIL
.: . :. . :. : . . .... .:..:.:: . . .: ...: .:..:.:
XP_011 QMGKFYPELKLAYAVRGNKLERGQ-KISE-QIVIGTPGTVLDWCSKLKFIDPKKIKVFVL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB0 DEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSD
:::: .. . :.: : :: . ::: :::. . . . : . ::. ..:. .
XP_011 DEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREE
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB0 PSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILS
.: .:::: . .: .:: : : .:.. : . ::..: . .. :. :: ::
XP_011 ETLDTIKQYYVLCSSR-------DEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELS
310 320 330 340 350
340 350 360 370 380 390
pF1KB0 SKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDW
..: . .::.: .:: .. .... . .::..:.. .::::.:.:..:.:.:.:.:
XP_011 KEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDK
360 370 380 390 400 410
400 410 420 430 440
pF1KB0 ------ETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCNINLLPLPDPIPSGL
:::.:::::.:::: ::.:.. . :.. :: .. :
XP_011 DGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEI
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB0 MEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNNSVSGL
XP_011 EKIAN
480
>>XP_011521134 (OMIM: 605812) PREDICTED: ATP-dependent R (539 aa)
initn: 644 init1: 215 opt: 679 Z-score: 608.6 bits: 123.0 E(85289): 3.7e-27
Smith-Waterman score: 679; 34.3% identity (64.6% similar) in 376 aa overlap (64-430:154-520)
40 50 60 70 80 90
pF1KB0 PGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAI
:: : :. .:.:. : ::.::: .: .:.
XP_011 KLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENAL
130 140 150 160 170 180
100 110 120 130 140 150
pF1KB0 PL--GRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVIT
:: .. .::.:..:::::: .: :... : : : :.:: :.:.: .::
XP_011 PLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIE
190 200 210 220 230 240
160 170 180 190 200 210
pF1KB0 AIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLI-ELDYLNPGSIRLFIL
.: . :. . :. : . . .... .:..:.:: . . .: ...: .:..:.:
XP_011 QMGKFYPELKLAYAVRGNKLERGQ-KISE-QIVIGTPGTVLDWCSKLKFIDPKKIKVFVL
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB0 DEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSD
:::: .. . :.: : :: . ::: :::. . . . : . ::. ..:. .
XP_011 DEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREE
310 320 330 340 350 360
280 290 300 310 320 330
pF1KB0 PSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILS
.: .:::: . .: .:: : : .:.. : . ::..: . .. :. :: ::
XP_011 ETLDTIKQYYVLCSSR-------DEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELS
370 380 390 400 410
340 350 360 370 380 390
pF1KB0 SKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDW
..: . .::.: .:: .. .... . .::..:.. .::::.:.:..:.:.:.:.:
XP_011 KEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDK
420 430 440 450 460 470
400 410 420 430 440
pF1KB0 ------ETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCNINLLPLPDPIPSGL
:::.:::::.:::: ::.:.. . :.. :: .. :
XP_011 DGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEI
480 490 500 510 520 530
450 460 470 480 490 500
pF1KB0 MEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNNSVSGL
XP_011 EKIAN
>>NP_001191439 (OMIM: 602641) eukaryotic initiation fact (347 aa)
initn: 294 init1: 264 opt: 653 Z-score: 588.7 bits: 118.6 E(85289): 4.7e-26
Smith-Waterman score: 653; 36.7% identity (68.8% similar) in 311 aa overlap (64-371:34-334)
40 50 60 70 80 90
pF1KB0 PGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAI
:... ::. .:.:. : :::.:: .: .::
NP_001 SQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAI
10 20 30 40 50 60
100 110 120 130 140 150
pF1KB0 -PLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITA
: . : :.:.::.:::::: .:. :... :. .:: :.::::::.: ::..:. :
NP_001 LPCIK-GYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMA
70 80 90 100 110 120
160 170 180 190 200 210
pF1KB0 IGIKMEGLECHVFIGGTPLSQD--KTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFIL
.: : : ::. :::: . . : ... :: ::.:::. .... ::.: :..:.:
NP_001 LGDYM-GASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVL
130 140 150 160 170 180
220 230 240 250 260 270
pF1KB0 DEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSD
::::..: .: :..:: :...: .. :.. .:::.: . .. :.:::: . ... .
NP_001 DEADEMLSRG-FKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE
190 200 210 220 230 240
280 290 300 310 320 330
pF1KB0 PSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILS
.: :..:.: :. : : . : .:. . ..::..: : . ... :.. .
NP_001 LTLEGIRQFYINVERE-------EWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH
250 260 270 280 290
340 350 360 370 380 390
pF1KB0 SKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDW
.. : . . :.:.:..: : ... ::::.::: ..
NP_001 ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLGKLYPQNRSRWTVWP
300 310 320 330 340
400 410 420 430 440 450
pF1KB0 ETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCNINLLPLPDPIPSGLMEECVD
824 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:51:44 2016 done: Mon Nov 7 18:51:46 2016
Total Scan time: 11.520 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]