Result of FASTA (omim) for
pFN21AA1844
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1844, 647 aa
1>>>pF1KA1844 647 - 647 aa - 647 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.2138+/-0.000428; mu= -29.1313+/- 0.026
mean_var=454.5894+/-95.861, 0's: 0 Z-trim(122.0): 37 B-trim: 0 in 0/60
Lambda= 0.060154
statistics sampled from 39491 (39541) to 39491 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.464), width: 16
Scan time: 12.920
The best scores are: opt bits E(85289)
NP_057712 (OMIM: 615049,616708) WW domain-containi ( 647) 4275 385.6 3e-106
XP_011517793 (OMIM: 615049,616708) PREDICTED: WW d ( 602) 3955 357.8 6.4e-98
NP_567822 (OMIM: 615049,616708) WW domain-containi ( 602) 3955 357.8 6.4e-98
XP_016871805 (OMIM: 615049,616708) PREDICTED: WW d ( 601) 3938 356.3 1.8e-97
XP_016871804 (OMIM: 615049,616708) PREDICTED: WW d ( 601) 3938 356.3 1.8e-97
NP_567823 (OMIM: 615049,616708) WW domain-containi ( 544) 2189 204.5 8e-52
XP_016871806 (OMIM: 615049,616708) PREDICTED: WW d ( 499) 2182 203.9 1.1e-51
XP_016871807 (OMIM: 615049,616708) PREDICTED: WW d ( 498) 2165 202.5 3.1e-51
>>NP_057712 (OMIM: 615049,616708) WW domain-containing a (647 aa)
initn: 4275 init1: 4275 opt: 4275 Z-score: 2028.5 bits: 385.6 E(85289): 3e-106
Smith-Waterman score: 4275; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647)
10 20 30 40 50 60
pF1KA1 MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 FPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 SSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 TVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSE
550 560 570 580 590 600
610 620 630 640
pF1KA1 ICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV
:::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV
610 620 630 640
>>XP_011517793 (OMIM: 615049,616708) PREDICTED: WW domai (602 aa)
initn: 3955 init1: 3955 opt: 3955 Z-score: 1879.0 bits: 357.8 E(85289): 6.4e-98
Smith-Waterman score: 3955; 100.0% identity (100.0% similar) in 602 aa overlap (46-647:1-602)
20 30 40 50 60 70
pF1KA1 HDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGH
::::::::::::::::::::::::::::::
XP_011 MRDAGDPSPPNKMLRRSDSPENKYSDSTGH
10 20 30
80 90 100 110 120 130
pF1KA1 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA1 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA1 ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH
160 170 180 190 200 210
260 270 280 290 300 310
pF1KA1 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV
220 230 240 250 260 270
320 330 340 350 360 370
pF1KA1 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
280 290 300 310 320 330
380 390 400 410 420 430
pF1KA1 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
340 350 360 370 380 390
440 450 460 470 480 490
pF1KA1 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
400 410 420 430 440 450
500 510 520 530 540 550
pF1KA1 QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
460 470 480 490 500 510
560 570 580 590 600 610
pF1KA1 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
520 530 540 550 560 570
620 630 640
pF1KA1 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
::::::::::::::::::::::::::::::::
XP_011 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
580 590 600
>>NP_567822 (OMIM: 615049,616708) WW domain-containing a (602 aa)
initn: 3955 init1: 3955 opt: 3955 Z-score: 1879.0 bits: 357.8 E(85289): 6.4e-98
Smith-Waterman score: 3955; 100.0% identity (100.0% similar) in 602 aa overlap (46-647:1-602)
20 30 40 50 60 70
pF1KA1 HDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGH
::::::::::::::::::::::::::::::
NP_567 MRDAGDPSPPNKMLRRSDSPENKYSDSTGH
10 20 30
80 90 100 110 120 130
pF1KA1 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA1 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA1 ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH
160 170 180 190 200 210
260 270 280 290 300 310
pF1KA1 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV
220 230 240 250 260 270
320 330 340 350 360 370
pF1KA1 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
280 290 300 310 320 330
380 390 400 410 420 430
pF1KA1 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
340 350 360 370 380 390
440 450 460 470 480 490
pF1KA1 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
400 410 420 430 440 450
500 510 520 530 540 550
pF1KA1 QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
460 470 480 490 500 510
560 570 580 590 600 610
pF1KA1 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
520 530 540 550 560 570
620 630 640
pF1KA1 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
::::::::::::::::::::::::::::::::
NP_567 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
580 590 600
>>XP_016871805 (OMIM: 615049,616708) PREDICTED: WW domai (601 aa)
initn: 3217 init1: 3123 opt: 3938 Z-score: 1871.0 bits: 356.3 E(85289): 1.8e-97
Smith-Waterman score: 3938; 99.8% identity (99.8% similar) in 602 aa overlap (46-647:1-601)
20 30 40 50 60 70
pF1KA1 HDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGH
::::::::::::::::::::::::::::::
XP_016 MRDAGDPSPPNKMLRRSDSPENKYSDSTGH
10 20 30
80 90 100 110 120 130
pF1KA1 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA1 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA1 ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH
160 170 180 190 200 210
260 270 280 290 300 310
pF1KA1 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV
220 230 240 250 260 270
320 330 340 350 360 370
pF1KA1 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
280 290 300 310 320 330
380 390 400 410 420 430
pF1KA1 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
340 350 360 370 380 390
440 450 460 470 480 490
pF1KA1 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
400 410 420 430 440 450
500 510 520 530 540 550
pF1KA1 QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 QQPVTADKQQGHEPVSPRSLQRSS-QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
460 470 480 490 500
560 570 580 590 600 610
pF1KA1 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
510 520 530 540 550 560
620 630 640
pF1KA1 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
::::::::::::::::::::::::::::::::
XP_016 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
570 580 590 600
>>XP_016871804 (OMIM: 615049,616708) PREDICTED: WW domai (601 aa)
initn: 3217 init1: 3123 opt: 3938 Z-score: 1871.0 bits: 356.3 E(85289): 1.8e-97
Smith-Waterman score: 3938; 99.8% identity (99.8% similar) in 602 aa overlap (46-647:1-601)
20 30 40 50 60 70
pF1KA1 HDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGH
::::::::::::::::::::::::::::::
XP_016 MRDAGDPSPPNKMLRRSDSPENKYSDSTGH
10 20 30
80 90 100 110 120 130
pF1KA1 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA1 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA1 ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH
160 170 180 190 200 210
260 270 280 290 300 310
pF1KA1 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV
220 230 240 250 260 270
320 330 340 350 360 370
pF1KA1 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
280 290 300 310 320 330
380 390 400 410 420 430
pF1KA1 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
340 350 360 370 380 390
440 450 460 470 480 490
pF1KA1 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
400 410 420 430 440 450
500 510 520 530 540 550
pF1KA1 QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 QQPVTADKQQGHEPVSPRSLQRSS-QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
460 470 480 490 500
560 570 580 590 600 610
pF1KA1 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
510 520 530 540 550 560
620 630 640
pF1KA1 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
::::::::::::::::::::::::::::::::
XP_016 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
570 580 590 600
>>NP_567823 (OMIM: 615049,616708) WW domain-containing a (544 aa)
initn: 2182 init1: 2182 opt: 2189 Z-score: 1051.4 bits: 204.5 E(85289): 8e-52
Smith-Waterman score: 3374; 83.9% identity (84.1% similar) in 647 aa overlap (1-647:1-544)
10 20 30 40 50 60
pF1KA1 MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 FPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETH
:::::::::::::::::::::::
NP_567 FPKDRDYRREVMQATATSGFASG-------------------------------------
190 200
250 260 270 280 290 300
pF1KA1 SSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA
NP_567 ------------------------------------------------------------
310 320 330 340 350 360
pF1KA1 QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDP
.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 ------KSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDP
210 220 230 240 250
370 380 390 400 410 420
pF1KA1 NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI
260 270 280 290 300 310
430 440 450 460 470 480
pF1KA1 SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV
320 330 340 350 360 370
490 500 510 520 530 540
pF1KA1 STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA
380 390 400 410 420 430
550 560 570 580 590 600
pF1KA1 TVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_567 TVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSE
440 450 460 470 480 490
610 620 630 640
pF1KA1 ICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV
:::::::::::::::::::::::::::::::::::::::::::::::
NP_567 ICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV
500 510 520 530 540
>>XP_016871806 (OMIM: 615049,616708) PREDICTED: WW domai (499 aa)
initn: 2182 init1: 2182 opt: 2182 Z-score: 1048.7 bits: 203.9 E(85289): 1.1e-51
Smith-Waterman score: 3054; 82.7% identity (82.9% similar) in 602 aa overlap (46-647:1-499)
20 30 40 50 60 70
pF1KA1 HDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGH
::::::::::::::::::::::::::::::
XP_016 MRDAGDPSPPNKMLRRSDSPENKYSDSTGH
10 20 30
80 90 100 110 120 130
pF1KA1 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA1 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA1 ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH
::::::::
XP_016 ATSGFASG----------------------------------------------------
260 270 280 290 300 310
pF1KA1 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV
.::::::::
XP_016 ---------------------------------------------------KSTSGDKPV
160
320 330 340 350 360 370
pF1KA1 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
170 180 190 200 210 220
380 390 400 410 420 430
pF1KA1 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
230 240 250 260 270 280
440 450 460 470 480 490
pF1KA1 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
290 300 310 320 330 340
500 510 520 530 540 550
pF1KA1 QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
350 360 370 380 390 400
560 570 580 590 600 610
pF1KA1 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
410 420 430 440 450 460
620 630 640
pF1KA1 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
::::::::::::::::::::::::::::::::
XP_016 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
470 480 490
>>XP_016871807 (OMIM: 615049,616708) PREDICTED: WW domai (498 aa)
initn: 2473 init1: 1349 opt: 2165 Z-score: 1040.8 bits: 202.5 E(85289): 3.1e-51
Smith-Waterman score: 3037; 82.6% identity (82.7% similar) in 602 aa overlap (46-647:1-498)
20 30 40 50 60 70
pF1KA1 HDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGH
::::::::::::::::::::::::::::::
XP_016 MRDAGDPSPPNKMLRRSDSPENKYSDSTGH
10 20 30
80 90 100 110 120 130
pF1KA1 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDW
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA1 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQAT
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA1 ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH
::::::::
XP_016 ATSGFASG----------------------------------------------------
260 270 280 290 300 310
pF1KA1 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV
.::::::::
XP_016 ---------------------------------------------------KSTSGDKPV
160
320 330 340 350 360 370
pF1KA1 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ
170 180 190 200 210 220
380 390 400 410 420 430
pF1KA1 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ
230 240 250 260 270 280
440 450 460 470 480 490
pF1KA1 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT
290 300 310 320 330 340
500 510 520 530 540 550
pF1KA1 QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 QQPVTADKQQGHEPVSPRSLQRSS-QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL
350 360 370 380 390 400
560 570 580 590 600 610
pF1KA1 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVC
410 420 430 440 450 460
620 630 640
pF1KA1 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
::::::::::::::::::::::::::::::::
XP_016 EIQATLREQRILFLRQQIKELEKLKNQNSFMV
470 480 490
647 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 04:40:12 2016 done: Mon Nov 7 04:40:14 2016
Total Scan time: 12.920 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]