Result of FASTA (omim) for
pFN21AA1461
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1461, 1494 aa
1>>>pF1KA1461 1494 - 1494 aa - 1494 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.4475+/-0.000472; mu= -27.0712+/- 0.029
mean_var=484.3719+/-101.083, 0's: 0 Z-trim(121.3): 38 B-trim: 62 in 1/59
Lambda= 0.058275
statistics sampled from 37792 (37830) to 37792 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.444), width: 16
Scan time: 21.110
The best scores are: opt bits E(85289)
NP_060798 (OMIM: 156200,611472) methyl-CpG-binding (1494) 10118 866.5 0
XP_016859974 (OMIM: 156200,611472) PREDICTED: meth (1507) 9653 827.4 0
XP_016859973 (OMIM: 156200,611472) PREDICTED: meth (1700) 6458 558.8 1.3e-157
XP_016859972 (OMIM: 156200,611472) PREDICTED: meth (1713) 6458 558.8 1.3e-157
XP_016859971 (OMIM: 156200,611472) PREDICTED: meth (1727) 6458 558.8 1.3e-157
XP_011509772 (OMIM: 156200,611472) PREDICTED: meth (1740) 6458 558.8 1.3e-157
XP_011509774 (OMIM: 156200,611472) PREDICTED: meth (1740) 6458 558.8 1.3e-157
>>NP_060798 (OMIM: 156200,611472) methyl-CpG-binding dom (1494 aa)
initn: 10118 init1: 10118 opt: 10118 Z-score: 4614.7 bits: 866.5 E(85289): 0
Smith-Waterman score: 10118; 99.9% identity (99.9% similar) in 1494 aa overlap (1-1494:1-1494)
10 20 30 40 50 60
pF1KA1 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGDMSSINNTLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGDMSSINNTLSN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 HQLTHLQSLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HQLTHLQSLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 MQEDAALLNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MQEDAALLNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 GDASVDAIYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GDASVDAIYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 SAVIHGRNMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SAVIHGRNMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 QSPRGERNRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QSPRGERNRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKIL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 EENFRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EENFRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 SSNSLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SSNSLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRP
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA1 RTFNVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RTFNVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490
pF1KA1 RKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRRKISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRRKISR
1450 1460 1470 1480 1490
>>XP_016859974 (OMIM: 156200,611472) PREDICTED: methyl-C (1507 aa)
initn: 9645 init1: 9645 opt: 9653 Z-score: 4403.3 bits: 827.4 E(85289): 0
Smith-Waterman score: 10082; 99.1% identity (99.1% similar) in 1507 aa overlap (1-1494:1-1507)
10 20 30 40 50 60
pF1KA1 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGDMSSINNTLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGDMSSINNTLSN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 HQLTHLQSLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQLTHLQSLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 MQEDAALLNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQEDAALLNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 GDASVDAIYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDASVDAIYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 SAVIHGRNMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAVIHGRNMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 QSPRGERNRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSPRGERNRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKIL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 EENFRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EENFRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 SSNSLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSNSLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRP
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420
pF1KA1 RTFNVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKV-------------EPEKL
:::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 RTFNVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKVWVMWFGLHTFTQVEPEKL
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KA1 KTLTEGLEAYSRVRKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTLTEGLEAYSRVRKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKP
1450 1460 1470 1480 1490 1500
1490
pF1KA1 KRRKISR
:::::::
XP_016 KRRKISR
>>XP_016859973 (OMIM: 156200,611472) PREDICTED: methyl-C (1700 aa)
initn: 6413 init1: 6413 opt: 6458 Z-score: 2950.8 bits: 558.8 E(85289): 1.3e-157
Smith-Waterman score: 8293; 84.7% identity (84.7% similar) in 1526 aa overlap (1-1293:1-1526)
10 20 30 40 50 60
pF1KA1 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
850 860 870 880 890 900
910 920 930 940
pF1KA1 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEG-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGKSEINLHPLGF
910 920 930 940 950 960
pF1KA1 ------------------------------------------------------------
XP_016 LNPNVNAALAFLSSDMDGQVLQPVHFQLLAALLQNQAQAAAMLPLPSFNLTISDLLQQQN
970 980 990 1000 1010 1020
pF1KA1 ------------------------------------------------------------
XP_016 TPLPSLTQMTAPPDHLPSNQSDNSRAETLLTSPLGNPLPSFAGSDTTFNPLFLPAVNGAS
1030 1040 1050 1060 1070 1080
pF1KA1 ------------------------------------------------------------
XP_016 GLMTLNPQLLGGVLNSASANTANHPEVSIATSSQATTTTTTTSSAVAALTVSTLGGTAVV
1090 1100 1110 1120 1130 1140
950 960
pF1KA1 ------------------------------------------DMSSINNTLSNHQLTHLQ
::::::::::::::::::
XP_016 SMAETLLNISNNAGNTPGPAKLNSNSVVPQLLNPLLGTGLLGDMSSINNTLSNHQLTHLQ
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KA1 SLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVIMQEDAAL
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 SLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVRMQEDAAL
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KA1 LNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGPGDASVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGPGDASVDA
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KA1 IYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAVSAVIHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAVSAVIHGR
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KA1 NMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGEQSPRGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGEQSPRGER
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250 1260
pF1KA1 NRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKILEENFRYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKILEENFRYN
1450 1460 1470 1480 1490 1500
1270 1280 1290 1300 1310 1320
pF1KA1 NYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSNSLEN
::::::::::::::::::::::::::
XP_016 NYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSNSLEN
1510 1520 1530 1540 1550 1560
>--
initn: 1025 init1: 1025 opt: 1025 Z-score: 482.2 bits: 102.1 E(85289): 4.1e-20
Smith-Waterman score: 1025; 100.0% identity (100.0% similar) in 153 aa overlap (1294-1446:1527-1679)
1270 1280 1290 1300 1310 1320
pF1KA1 FRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSN
::::::::::::::::::::::::::::::
XP_016 FRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSN
1500 1510 1520 1530 1540 1550
1330 1340 1350 1360 1370 1380
pF1KA1 SLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTF
1560 1570 1580 1590 1600 1610
1390 1400 1410 1420 1430 1440
pF1KA1 NVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRVRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRVRKR
1620 1630 1640 1650 1660 1670
1450 1460 1470 1480 1490
pF1KA1 NRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRRKISR
:::
XP_016 NRKLRGRRKEEKAEKGRCHLEQDN
1680 1690 1700
>>XP_016859972 (OMIM: 156200,611472) PREDICTED: methyl-C (1713 aa)
initn: 6555 init1: 6413 opt: 6458 Z-score: 2950.7 bits: 558.8 E(85289): 1.3e-157
Smith-Waterman score: 8293; 84.7% identity (84.7% similar) in 1526 aa overlap (1-1293:1-1526)
10 20 30 40 50 60
pF1KA1 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
850 860 870 880 890 900
910 920 930 940
pF1KA1 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEG-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGKSEINLHPLGF
910 920 930 940 950 960
pF1KA1 ------------------------------------------------------------
XP_016 LNPNVNAALAFLSSDMDGQVLQPVHFQLLAALLQNQAQAAAMLPLPSFNLTISDLLQQQN
970 980 990 1000 1010 1020
pF1KA1 ------------------------------------------------------------
XP_016 TPLPSLTQMTAPPDHLPSNQSDNSRAETLLTSPLGNPLPSFAGSDTTFNPLFLPAVNGAS
1030 1040 1050 1060 1070 1080
pF1KA1 ------------------------------------------------------------
XP_016 GLMTLNPQLLGGVLNSASANTANHPEVSIATSSQATTTTTTTSSAVAALTVSTLGGTAVV
1090 1100 1110 1120 1130 1140
950 960
pF1KA1 ------------------------------------------DMSSINNTLSNHQLTHLQ
::::::::::::::::::
XP_016 SMAETLLNISNNAGNTPGPAKLNSNSVVPQLLNPLLGTGLLGDMSSINNTLSNHQLTHLQ
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KA1 SLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVIMQEDAAL
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 SLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVRMQEDAAL
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KA1 LNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGPGDASVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGPGDASVDA
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KA1 IYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAVSAVIHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAVSAVIHGR
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KA1 NMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGEQSPRGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGEQSPRGER
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250 1260
pF1KA1 NRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKILEENFRYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKILEENFRYN
1450 1460 1470 1480 1490 1500
1270 1280 1290 1300 1310 1320
pF1KA1 NYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSNSLEN
::::::::::::::::::::::::::
XP_016 NYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSNSLEN
1510 1520 1530 1540 1550 1560
>--
initn: 876 init1: 876 opt: 989 Z-score: 465.7 bits: 99.0 E(85289): 3.3e-19
Smith-Waterman score: 989; 92.2% identity (92.2% similar) in 166 aa overlap (1294-1446:1527-1692)
1270 1280 1290 1300 1310 1320
pF1KA1 FRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSN
::::::::::::::::::::::::::::::
XP_016 FRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSN
1500 1510 1520 1530 1540 1550
1330 1340 1350 1360 1370 1380
pF1KA1 SLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTF
1560 1570 1580 1590 1600 1610
1390 1400 1410 1420 1430
pF1KA1 NVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKV-------------EPEKLKTL
::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 NVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKVWVMWFGLHTFTQVEPEKLKTL
1620 1630 1640 1650 1660 1670
1440 1450 1460 1470 1480 1490
pF1KA1 TEGLEAYSRVRKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRR
::::::::::::::::
XP_016 TEGLEAYSRVRKRNRKLRGRRKEEKAEKGRCHLEQDN
1680 1690 1700 1710
>>XP_016859971 (OMIM: 156200,611472) PREDICTED: methyl-C (1727 aa)
initn: 6413 init1: 6413 opt: 6458 Z-score: 2950.6 bits: 558.8 E(85289): 1.3e-157
Smith-Waterman score: 8293; 84.7% identity (84.7% similar) in 1526 aa overlap (1-1293:1-1526)
10 20 30 40 50 60
pF1KA1 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
850 860 870 880 890 900
910 920 930 940
pF1KA1 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEG-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGKSEINLHPLGF
910 920 930 940 950 960
pF1KA1 ------------------------------------------------------------
XP_016 LNPNVNAALAFLSSDMDGQVLQPVHFQLLAALLQNQAQAAAMLPLPSFNLTISDLLQQQN
970 980 990 1000 1010 1020
pF1KA1 ------------------------------------------------------------
XP_016 TPLPSLTQMTAPPDHLPSNQSDNSRAETLLTSPLGNPLPSFAGSDTTFNPLFLPAVNGAS
1030 1040 1050 1060 1070 1080
pF1KA1 ------------------------------------------------------------
XP_016 GLMTLNPQLLGGVLNSASANTANHPEVSIATSSQATTTTTTTSSAVAALTVSTLGGTAVV
1090 1100 1110 1120 1130 1140
950 960
pF1KA1 ------------------------------------------DMSSINNTLSNHQLTHLQ
::::::::::::::::::
XP_016 SMAETLLNISNNAGNTPGPAKLNSNSVVPQLLNPLLGTGLLGDMSSINNTLSNHQLTHLQ
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KA1 SLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVIMQEDAAL
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 SLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVRMQEDAAL
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KA1 LNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGPGDASVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGPGDASVDA
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KA1 IYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAVSAVIHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAVSAVIHGR
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KA1 NMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGEQSPRGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGEQSPRGER
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250 1260
pF1KA1 NRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKILEENFRYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKILEENFRYN
1450 1460 1470 1480 1490 1500
1270 1280 1290 1300 1310 1320
pF1KA1 NYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSNSLEN
::::::::::::::::::::::::::
XP_016 NYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSNSLEN
1510 1520 1530 1540 1550 1560
>--
initn: 1349 init1: 1349 opt: 1349 Z-score: 629.3 bits: 129.3 E(85289): 2.6e-28
Smith-Waterman score: 1349; 100.0% identity (100.0% similar) in 201 aa overlap (1294-1494:1527-1727)
1270 1280 1290 1300 1310 1320
pF1KA1 FRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSN
::::::::::::::::::::::::::::::
XP_016 FRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSN
1500 1510 1520 1530 1540 1550
1330 1340 1350 1360 1370 1380
pF1KA1 SLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTF
1560 1570 1580 1590 1600 1610
1390 1400 1410 1420 1430 1440
pF1KA1 NVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRVRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRVRKR
1620 1630 1640 1650 1660 1670
1450 1460 1470 1480 1490
pF1KA1 NRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRRKISR
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRRKISR
1680 1690 1700 1710 1720
>>XP_011509772 (OMIM: 156200,611472) PREDICTED: methyl-C (1740 aa)
initn: 6879 init1: 6413 opt: 6458 Z-score: 2950.6 bits: 558.8 E(85289): 1.3e-157
Smith-Waterman score: 8293; 84.7% identity (84.7% similar) in 1526 aa overlap (1-1293:1-1526)
10 20 30 40 50 60
pF1KA1 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
850 860 870 880 890 900
910 920 930 940
pF1KA1 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEG-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGKSEINLHPLGF
910 920 930 940 950 960
pF1KA1 ------------------------------------------------------------
XP_011 LNPNVNAALAFLSSDMDGQVLQPVHFQLLAALLQNQAQAAAMLPLPSFNLTISDLLQQQN
970 980 990 1000 1010 1020
pF1KA1 ------------------------------------------------------------
XP_011 TPLPSLTQMTAPPDHLPSNQSDNSRAETLLTSPLGNPLPSFAGSDTTFNPLFLPAVNGAS
1030 1040 1050 1060 1070 1080
pF1KA1 ------------------------------------------------------------
XP_011 GLMTLNPQLLGGVLNSASANTANHPEVSIATSSQATTTTTTTSSAVAALTVSTLGGTAVV
1090 1100 1110 1120 1130 1140
950 960
pF1KA1 ------------------------------------------DMSSINNTLSNHQLTHLQ
::::::::::::::::::
XP_011 SMAETLLNISNNAGNTPGPAKLNSNSVVPQLLNPLLGTGLLGDMSSINNTLSNHQLTHLQ
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KA1 SLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVIMQEDAAL
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_011 SLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVRMQEDAAL
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KA1 LNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGPGDASVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGPGDASVDA
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KA1 IYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAVSAVIHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAVSAVIHGR
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KA1 NMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGEQSPRGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGEQSPRGER
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250 1260
pF1KA1 NRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKILEENFRYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKILEENFRYN
1450 1460 1470 1480 1490 1500
1270 1280 1290 1300 1310 1320
pF1KA1 NYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSNSLEN
::::::::::::::::::::::::::
XP_011 NYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSNSLEN
1510 1520 1530 1540 1550 1560
>--
initn: 876 init1: 876 opt: 1313 Z-score: 612.9 bits: 126.3 E(85289): 2.1e-27
Smith-Waterman score: 1313; 93.9% identity (93.9% similar) in 214 aa overlap (1294-1494:1527-1740)
1270 1280 1290 1300 1310 1320
pF1KA1 FRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSN
::::::::::::::::::::::::::::::
XP_011 FRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSN
1500 1510 1520 1530 1540 1550
1330 1340 1350 1360 1370 1380
pF1KA1 SLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTF
1560 1570 1580 1590 1600 1610
1390 1400 1410 1420 1430
pF1KA1 NVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKV-------------EPEKLKTL
::::::::::::::::::::::::::::::::::::::: ::::::::
XP_011 NVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKVWVMWFGLHTFTQVEPEKLKTL
1620 1630 1640 1650 1660 1670
1440 1450 1460 1470 1480 1490
pF1KA1 TEGLEAYSRVRKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEGLEAYSRVRKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRR
1680 1690 1700 1710 1720 1730
pF1KA1 KISR
::::
XP_011 KISR
1740
>>XP_011509774 (OMIM: 156200,611472) PREDICTED: methyl-C (1740 aa)
initn: 6879 init1: 6413 opt: 6458 Z-score: 2950.6 bits: 558.8 E(85289): 1.3e-157
Smith-Waterman score: 8293; 84.7% identity (84.7% similar) in 1526 aa overlap (1-1293:1-1526)
10 20 30 40 50 60
pF1KA1 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMIGSSNAMGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDPIPSKPVNQNPVIINPTSFHSNVHSQVPMMNVSMPPAVVPLPSNLPLPTVKPGHMNHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATSSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPTASAGSSSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDALRKRK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNST
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGCGASNTALPCSANQLHFTDPSMNSSVLQNIPLRGEAVHCHNANTNFVHSNSPVPNHHL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHF
850 860 870 880 890 900
910 920 930 940
pF1KA1 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEG-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGKSEINLHPLGF
910 920 930 940 950 960
pF1KA1 ------------------------------------------------------------
XP_011 LNPNVNAALAFLSSDMDGQVLQPVHFQLLAALLQNQAQAAAMLPLPSFNLTISDLLQQQN
970 980 990 1000 1010 1020
pF1KA1 ------------------------------------------------------------
XP_011 TPLPSLTQMTAPPDHLPSNQSDNSRAETLLTSPLGNPLPSFAGSDTTFNPLFLPAVNGAS
1030 1040 1050 1060 1070 1080
pF1KA1 ------------------------------------------------------------
XP_011 GLMTLNPQLLGGVLNSASANTANHPEVSIATSSQATTTTTTTSSAVAALTVSTLGGTAVV
1090 1100 1110 1120 1130 1140
950 960
pF1KA1 ------------------------------------------DMSSINNTLSNHQLTHLQ
::::::::::::::::::
XP_011 SMAETLLNISNNAGNTPGPAKLNSNSVVPQLLNPLLGTGLLGDMSSINNTLSNHQLTHLQ
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KA1 SLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVIMQEDAAL
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_011 SLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVRMQEDAAL
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KA1 LNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGPGDASVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNKRISTQPGLTALPENPNTTLPPFQDTPCELQPRIDPSLGQQVKDGLVVGGPGDASVDA
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KA1 IYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAVSAVIHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLNLSSAVSAVIHGR
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KA1 NMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGEQSPRGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMGGVDHDGRLRNSRGARLPKNLDHGKNVNEGDGFEYFKSASCHTSKKQWDGEQSPRGER
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250 1260
pF1KA1 NRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKILEENFRYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRWKYEEFLDHPGHIHSSPCHERPNNVSTLPFLPGEQHPILLPPRNCPGDKILEENFRYN
1450 1460 1470 1480 1490 1500
1270 1280 1290 1300 1310 1320
pF1KA1 NYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSNSLEN
::::::::::::::::::::::::::
XP_011 NYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSNSLEN
1510 1520 1530 1540 1550 1560
>--
initn: 876 init1: 876 opt: 1313 Z-score: 612.9 bits: 126.3 E(85289): 2.1e-27
Smith-Waterman score: 1313; 93.9% identity (93.9% similar) in 214 aa overlap (1294-1494:1527-1740)
1270 1280 1290 1300 1310 1320
pF1KA1 FRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSN
::::::::::::::::::::::::::::::
XP_011 FRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTAKQDLVLEEQSPSSSN
1500 1510 1520 1530 1540 1550
1330 1340 1350 1360 1370 1380
pF1KA1 SLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTF
1560 1570 1580 1590 1600 1610
1390 1400 1410 1420 1430
pF1KA1 NVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKV-------------EPEKLKTL
::::::::::::::::::::::::::::::::::::::: ::::::::
XP_011 NVGDLVWGQIKGLTSWPGKLVREDDVHNSCQQSPEEGKVWVMWFGLHTFTQVEPEKLKTL
1620 1630 1640 1650 1660 1670
1440 1450 1460 1470 1480 1490
pF1KA1 TEGLEAYSRVRKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEGLEAYSRVRKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRR
1680 1690 1700 1710 1720 1730
pF1KA1 KISR
::::
XP_011 KISR
1740
1494 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:46:40 2016 done: Mon Nov 7 03:46:43 2016
Total Scan time: 21.110 Total Display time: 0.760
Function used was FASTA [36.3.4 Apr, 2011]