Result of FASTA (omim) for
pFN21AA0413
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0413, 1237 aa
1>>>pF1KA0413 1237 - 1237 aa - 1237 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9670+/-0.000676; mu= 14.2891+/- 0.041
mean_var=189.6322+/-40.685, 0's: 0 Z-trim(108.7): 310 B-trim: 14 in 1/50
Lambda= 0.093136
statistics sampled from 16476 (16852) to 16476 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.538), E-opt: 0.2 (0.198), width: 16
Scan time: 14.570
The best scores are: opt bits E(85289)
NP_037361 (OMIM: 602233) apoptotic protease-activa (1237) 8373 1140.2 0
NP_863651 (OMIM: 602233) apoptotic protease-activa (1248) 7765 1058.5 0
NP_001151 (OMIM: 602233) apoptotic protease-activa (1194) 5646 773.8 0
NP_863658 (OMIM: 602233) apoptotic protease-activa (1205) 5038 692.1 5.9e-198
NP_863659 (OMIM: 602233) apoptotic protease-activa ( 338) 1421 205.4 5.2e-52
XP_016874739 (OMIM: 602233) PREDICTED: apoptotic p ( 327) 1414 204.5 9.8e-52
NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 368 63.9 2.1e-09
XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 337 59.7 3.6e-08
XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 337 59.7 3.6e-08
XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 337 59.7 3.6e-08
XP_016860390 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 337 59.7 3.6e-08
XP_016860387 (OMIM: 612173) PREDICTED: sperm-assoc ( 390) 337 59.8 4e-08
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 335 59.5 4.4e-08
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 335 59.5 4.4e-08
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 335 59.5 4.4e-08
XP_016860385 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 337 60.0 4.8e-08
XP_016860386 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 337 60.0 4.8e-08
XP_011510124 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 337 60.0 4.9e-08
XP_011510125 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 337 60.0 4.9e-08
XP_011510123 (OMIM: 612173) PREDICTED: sperm-assoc ( 537) 337 60.0 4.9e-08
XP_011510120 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 337 60.0 5.2e-08
XP_011510121 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 337 60.0 5.2e-08
XP_011510119 (OMIM: 612173) PREDICTED: sperm-assoc ( 582) 337 60.0 5.2e-08
XP_011510118 (OMIM: 612173) PREDICTED: sperm-assoc ( 592) 337 60.0 5.3e-08
XP_011510117 (OMIM: 612173) PREDICTED: sperm-assoc ( 592) 337 60.0 5.3e-08
XP_011510116 (OMIM: 612173) PREDICTED: sperm-assoc ( 600) 337 60.0 5.3e-08
NP_078808 (OMIM: 612173) sperm-associated antigen ( 631) 337 60.1 5.5e-08
NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 330 58.8 6.7e-08
NP_056441 (OMIM: 610091) WD repeat and SOCS box-co ( 421) 323 58.0 1.6e-07
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 299 54.6 1.2e-06
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 299 54.6 1.2e-06
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 299 54.6 1.2e-06
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 299 54.7 1.3e-06
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 299 54.7 1.3e-06
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 299 54.7 1.3e-06
NP_006775 (OMIM: 604737) WD repeat-containing prot ( 943) 305 56.0 1.4e-06
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 299 54.7 1.4e-06
NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 295 54.2 2.2e-06
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 295 54.3 2.3e-06
XP_016879922 (OMIM: 610091) PREDICTED: WD repeat a ( 383) 288 53.2 3.8e-06
NP_599027 (OMIM: 610091) WD repeat and SOCS box-co ( 275) 274 51.2 1.1e-05
NP_599020 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 266 50.4 3.6e-05
NP_599021 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 266 50.4 3.6e-05
NP_150600 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 266 50.4 3.6e-05
XP_005262629 (OMIM: 400033) PREDICTED: F-box-like/ ( 536) 266 50.4 3.7e-05
XP_016885576 (OMIM: 400033) PREDICTED: F-box-like/ ( 540) 266 50.5 3.7e-05
XP_016885575 (OMIM: 400033) PREDICTED: F-box-like/ ( 577) 266 50.5 3.9e-05
NP_620640 (OMIM: 601787) transcription initiation ( 745) 266 50.6 4.6e-05
NP_001132940 (OMIM: 300196) F-box-like/WD repeat-c ( 526) 262 49.9 5.3e-05
XP_011543873 (OMIM: 300196) PREDICTED: F-box-like/ ( 526) 262 49.9 5.3e-05
>>NP_037361 (OMIM: 602233) apoptotic protease-activating (1237 aa)
initn: 8373 init1: 8373 opt: 8373 Z-score: 6096.5 bits: 1140.2 E(85289): 0
Smith-Waterman score: 8373; 99.9% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237)
10 20 30 40 50 60
pF1KA0 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSVRTVLCEGGVPQRPVVFVTRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSVRTVLCEGGVPQRPVVFVTRKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSIS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 ASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 DPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 NHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 NHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWET
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 KKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 HLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 HLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 WQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 WQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 RIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWNVVTGESSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 RIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWNVVTGESSQ
1150 1160 1170 1180 1190 1200
1210 1220 1230
pF1KA0 TFYTNGTNLKKIHVSPDFKTYVTVDNLGIIYILQTLE
:::::::::::::::::::::::::::::.:::::::
NP_037 TFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
1210 1220 1230
>>NP_863651 (OMIM: 602233) apoptotic protease-activating (1248 aa)
initn: 7757 init1: 7757 opt: 7765 Z-score: 5655.0 bits: 1058.5 E(85289): 0
Smith-Waterman score: 8341; 99.0% identity (99.1% similar) in 1248 aa overlap (1-1237:1-1248)
10 20 30 40 50 60
pF1KA0 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
10 20 30 40 50 60
70 80 90 100
pF1KA0 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSS-----------VRTVLCEGGVP
:::::::::::::::::::::::::::::::::::::: :::::::::::
NP_863 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA0 KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA0 MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAV
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA0 SENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 SENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINK
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA0 KNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 KNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA0 LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA0 SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA0 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHH
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA0 STIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 STIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTS
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA0 SDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 SDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLT
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA0 EAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 EAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA0 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKD
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA0 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA0 LLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 LLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIK
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230
pF1KA0 WWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGIIYILQTLE
::::::::::::::::::::::::::::::::::::::::.:::::::
NP_863 WWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
1210 1220 1230 1240
>>NP_001151 (OMIM: 602233) apoptotic protease-activating (1194 aa)
initn: 5473 init1: 5473 opt: 5646 Z-score: 4116.4 bits: 773.8 E(85289): 0
Smith-Waterman score: 7979; 96.4% identity (96.5% similar) in 1237 aa overlap (1-1237:1-1194)
10 20 30 40 50 60
pF1KA0 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSVRTVLCEGGVPQRPVVFVTRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSVRTVLCEGGVPQRPVVFVTRKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSIS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 DPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQ
::::::::::::::::::::::::::::::::
NP_001 DPQEDMEVIVKCCSWSADGARIMVAAKNKIFL----------------------------
790 800 810
850 860 870 880 890 900
pF1KA0 NHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWET
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---------------WNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWET
820 830 840 850
910 920 930 940 950 960
pF1KA0 KKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSP
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KA0 HLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWN
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KA0 WQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KA0 DISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEI
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KA0 RIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWNVVTGESSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWNVVTGESSQ
1100 1110 1120 1130 1140 1150
1210 1220 1230
pF1KA0 TFYTNGTNLKKIHVSPDFKTYVTVDNLGIIYILQTLE
:::::::::::::::::::::::::::::.:::::::
NP_001 TFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
1160 1170 1180 1190
>>NP_863658 (OMIM: 602233) apoptotic protease-activating (1205 aa)
initn: 4857 init1: 4857 opt: 5038 Z-score: 3674.9 bits: 692.1 E(85289): 5.9e-198
Smith-Waterman score: 7947; 95.6% identity (95.7% similar) in 1248 aa overlap (1-1237:1-1205)
10 20 30 40 50 60
pF1KA0 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
10 20 30 40 50 60
70 80 90 100
pF1KA0 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSS-----------VRTVLCEGGVP
:::::::::::::::::::::::::::::::::::::: :::::::::::
NP_863 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA0 KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA0 MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAV
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA0 SENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 SENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINK
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA0 KNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 KNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA0 LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA0 SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA0 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHH
:::::::::::::::::::::::::::::::::::::::::::
NP_863 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFL-----------------
790 800 810 820
830 840 850 860 870 880
pF1KA0 STIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTS
::::::::::::::::::::::::::::::::::
NP_863 --------------------------WNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTS
830 840 850
890 900 910 920 930 940
pF1KA0 SDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 SDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLT
860 870 880 890 900 910
950 960 970 980 990 1000
pF1KA0 EAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 EAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS
920 930 940 950 960 970
1010 1020 1030 1040 1050 1060
pF1KA0 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKD
980 990 1000 1010 1020 1030
1070 1080 1090 1100 1110 1120
pF1KA0 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST
1040 1050 1060 1070 1080 1090
1130 1140 1150 1160 1170 1180
pF1KA0 LLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 LLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIK
1100 1110 1120 1130 1140 1150
1190 1200 1210 1220 1230
pF1KA0 WWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGIIYILQTLE
::::::::::::::::::::::::::::::::::::::::.:::::::
NP_863 WWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
1160 1170 1180 1190 1200
>>NP_863659 (OMIM: 602233) apoptotic protease-activating (338 aa)
initn: 1406 init1: 1406 opt: 1421 Z-score: 1054.7 bits: 205.4 E(85289): 5.2e-52
Smith-Waterman score: 1997; 92.0% identity (93.8% similar) in 338 aa overlap (1-327:1-335)
10 20 30 40 50 60
pF1KA0 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
10 20 30 40 50 60
70 80 90 100
pF1KA0 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSS-----------VRTVLCEGGVP
:::::::::::::::::::::::::::::::::::::: :::::::::::
NP_863 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_863 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
:::::::::::::::::: .: ..: :. ..:
NP_863 MKKADLPEQAHSIIKECK---VVERCHWGILTDLLHKWNQS
310 320 330
350 360 370 380 390 400
pF1KA0 YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
>>XP_016874739 (OMIM: 602233) PREDICTED: apoptotic prote (327 aa)
initn: 1406 init1: 1406 opt: 1414 Z-score: 1049.8 bits: 204.5 E(85289): 9.8e-52
Smith-Waterman score: 1990; 96.5% identity (96.5% similar) in 318 aa overlap (1-307:1-318)
10 20 30 40 50 60
pF1KA0 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
10 20 30 40 50 60
70 80 90 100
pF1KA0 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSS-----------VRTVLCEGGVP
:::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
::::::::::::::::::
XP_016 MKKADLPEQAHSIIKECKDRVSHCSSG
310 320
>>NP_004805 (OMIM: 607797) U5 small nuclear ribonucleopr (357 aa)
initn: 280 init1: 125 opt: 368 Z-score: 289.8 bits: 63.9 E(85289): 2.1e-09
Smith-Waterman score: 368; 27.4% identity (60.7% similar) in 270 aa overlap (582-849:89-347)
560 570 580 590 600 610
pF1KA0 IVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHAC
: : : . : . : . :. ::..
NP_004 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATL--KGHSGAVMELH
60 70 80 90 100 110
620 630 640 650 660 670
pF1KA0 FSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFST-DDRFIATCSVDKKV
.. ::. . : ..:::. :. .::::.. ..:.: . : : . ... : : : :
NP_004 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV
120 130 140 150 160 170
680 690 700 710 720 730
pF1KA0 KIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFG
:.:. ..:. ... :: :...: ... .:. : .:.::: :.. :: :
NP_004 KLWDIRKKAAIQTF-QNTYQVLAVTFNDTSDQII--SGGIDNDIKVWDLRQNKLTYTMRG
180 190 200 210 220 230
740 750 760 770 780 790
pF1KA0 HTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIV
:..::. .: . . : : . :.:...::. .. :: : :... .... .
NP_004 HADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERC-VKIFQGNVHNFEKNL---L
240 250 260 270 280
800 810 820 830 840
pF1KA0 KCCSWSADGARIMVAAKNK-IFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALS
.: ::: ::..: ... .. ....: . .: .. :: ..:. : :.. . . : :
NP_004 RC-SWSPDGSKIAAGSADRFVYVWDTTSRRILYKL-PGHAGSINEVAFHPDEPIIISASS
290 300 310 320 330 340
850 860 870 880 890 900
pF1KA0 QYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAV
NP_004 DKRLYMGEIQ
350
>>XP_011510137 (OMIM: 612173) PREDICTED: sperm-associate (323 aa)
initn: 580 init1: 184 opt: 337 Z-score: 267.8 bits: 59.7 E(85289): 3.6e-08
Smith-Waterman score: 376; 28.9% identity (58.4% similar) in 305 aa overlap (599-898:39-322)
570 580 590 600 610 620
pF1KA0 AKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQR--IASCGADK
. : : : .: : . .. ..::: :.
XP_011 EFPIDMQPNPNLNVSKESLSPAKFDYKLKNIFRLHELPV--SCVSMQPHKDILVSCGEDR
10 20 30 40 50 60
630 640 650 660 670 680
pF1KA0 TLQVFKAETGEKLLEIKAHEDEVL-CCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYD
.:. . :: .: : . :: . :. .:: : : ::.:. :. . :..
XP_011 LWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDK-LATSSGDTTVKLWDLCKGDCILTFE
70 80 90 100 110 120
690 700 710 720 730 740
pF1KA0 EHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDK
::. : : . . .. ..:..: : :.::.:...:: :..:::.::: .: : ..
XP_011 GHSRAVWSCTWHSCGN--FVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSN
130 140 150 160 170 180
750 760 770 780 790 800
pF1KA0 LLASCSADGTLKLWDATSANERKSINVKQFFLN--LEDPQEDMEVIVKCCSWSADGARIM
: . ::: ::..::: .. ..:. .. .: . ::. : :..: .: :
XP_011 TLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHM--IASC---DACG----
190 200 210 220 230
810 820 830 840 850 860
pF1KA0 VAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSK
..: :.:.. . : : : . .:. .... . : .. ..: . : ..
XP_011 -VTK----LWDFRKLLPIVSIDIGP-SPGNEVNFDSSGRVLAQASGNGVIHLLDLKS-GE
240 250 260 270 280
870 880 890 900 910 920
pF1KA0 VADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENE
. :: . .: :.:: :: ......: :.: :
XP_011 IHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS
290 300 310 320
930 940 950 960 970 980
pF1KA0 VMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVNNR
>>XP_016860391 (OMIM: 612173) PREDICTED: sperm-associate (323 aa)
initn: 580 init1: 184 opt: 337 Z-score: 267.8 bits: 59.7 E(85289): 3.6e-08
Smith-Waterman score: 376; 28.9% identity (58.4% similar) in 305 aa overlap (599-898:39-322)
570 580 590 600 610 620
pF1KA0 AKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQR--IASCGADK
. : : : .: : . .. ..::: :.
XP_016 EFPIDMQPNPNLNVSKESLSPAKFDYKLKNIFRLHELPV--SCVSMQPHKDILVSCGEDR
10 20 30 40 50 60
630 640 650 660 670 680
pF1KA0 TLQVFKAETGEKLLEIKAHEDEVL-CCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYD
.:. . :: .: : . :: . :. .:: : : ::.:. :. . :..
XP_016 LWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDK-LATSSGDTTVKLWDLCKGDCILTFE
70 80 90 100 110 120
690 700 710 720 730 740
pF1KA0 EHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDK
::. : : . . .. ..:..: : :.::.:...:: :..:::.::: .: : ..
XP_016 GHSRAVWSCTWHSCGN--FVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSN
130 140 150 160 170 180
750 760 770 780 790 800
pF1KA0 LLASCSADGTLKLWDATSANERKSINVKQFFLN--LEDPQEDMEVIVKCCSWSADGARIM
: . ::: ::..::: .. ..:. .. .: . ::. : :..: .: :
XP_016 TLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHM--IASC---DACG----
190 200 210 220 230
810 820 830 840 850 860
pF1KA0 VAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSK
..: :.:.. . : : : . .:. .... . : .. ..: . : ..
XP_016 -VTK----LWDFRKLLPIVSIDIGP-SPGNEVNFDSSGRVLAQASGNGVIHLLDLKS-GE
240 250 260 270 280
870 880 890 900 910 920
pF1KA0 VADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENE
. :: . .: :.:: :: ......: :.: :
XP_016 IHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS
290 300 310 320
930 940 950 960 970 980
pF1KA0 VMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVNNR
>>XP_016860389 (OMIM: 612173) PREDICTED: sperm-associate (323 aa)
initn: 580 init1: 184 opt: 337 Z-score: 267.8 bits: 59.7 E(85289): 3.6e-08
Smith-Waterman score: 376; 28.9% identity (58.4% similar) in 305 aa overlap (599-898:39-322)
570 580 590 600 610 620
pF1KA0 AKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQR--IASCGADK
. : : : .: : . .. ..::: :.
XP_016 EFPIDMQPNPNLNVSKESLSPAKFDYKLKNIFRLHELPV--SCVSMQPHKDILVSCGEDR
10 20 30 40 50 60
630 640 650 660 670 680
pF1KA0 TLQVFKAETGEKLLEIKAHEDEVL-CCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYD
.:. . :: .: : . :: . :. .:: : : ::.:. :. . :..
XP_016 LWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDK-LATSSGDTTVKLWDLCKGDCILTFE
70 80 90 100 110 120
690 700 710 720 730 740
pF1KA0 EHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDK
::. : : . . .. ..:..: : :.::.:...:: :..:::.::: .: : ..
XP_016 GHSRAVWSCTWHSCGN--FVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSN
130 140 150 160 170 180
750 760 770 780 790 800
pF1KA0 LLASCSADGTLKLWDATSANERKSINVKQFFLN--LEDPQEDMEVIVKCCSWSADGARIM
: . ::: ::..::: .. ..:. .. .: . ::. : :..: .: :
XP_016 TLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHM--IASC---DACG----
190 200 210 220 230
810 820 830 840 850 860
pF1KA0 VAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSK
..: :.:.. . : : : . .:. .... . : .. ..: . : ..
XP_016 -VTK----LWDFRKLLPIVSIDIGP-SPGNEVNFDSSGRVLAQASGNGVIHLLDLKS-GE
240 250 260 270 280
870 880 890 900 910 920
pF1KA0 VADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENE
. :: . .: :.:: :: ......: :.: :
XP_016 IHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS
290 300 310 320
930 940 950 960 970 980
pF1KA0 VMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVNNR
1237 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 04:37:49 2016 done: Mon Nov 7 04:37:51 2016
Total Scan time: 14.570 Total Display time: 0.350
Function used was FASTA [36.3.4 Apr, 2011]