Result of FASTA (ccds) for
pFN21AA0413
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0413, 1237 aa
1>>>pF1KA0413 1237 - 1237 aa - 1237 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9888+/-0.00146; mu= 7.9367+/- 0.084
mean_var=154.5288+/-33.656, 0's: 0 Z-trim(102.3): 176 B-trim: 3 in 1/49
Lambda= 0.103174
statistics sampled from 6700 (6907) to 6700 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.552), E-opt: 0.2 (0.212), width: 16
Scan time: 4.340
The best scores are: opt bits E(32554)
CCDS55862.1 APAF1 gene_id:317|Hs108|chr12 (1237) 8373 1260.3 0
CCDS9069.1 APAF1 gene_id:317|Hs108|chr12 (1248) 7765 1169.8 0
CCDS55863.1 APAF1 gene_id:317|Hs108|chr12 (1194) 5646 854.4 0
CCDS9070.1 APAF1 gene_id:317|Hs108|chr12 (1205) 5038 763.9 0
CCDS9071.1 APAF1 gene_id:317|Hs108|chr12 ( 338) 1421 225.2 2.3e-58
CCDS340.1 SNRNP40 gene_id:9410|Hs108|chr1 ( 357) 368 68.4 3.6e-11
>>CCDS55862.1 APAF1 gene_id:317|Hs108|chr12 (1237 aa)
initn: 8373 init1: 8373 opt: 8373 Z-score: 6745.5 bits: 1260.3 E(32554): 0
Smith-Waterman score: 8373; 99.9% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237)
10 20 30 40 50 60
pF1KA0 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSVRTVLCEGGVPQRPVVFVTRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSVRTVLCEGGVPQRPVVFVTRKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSIS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 DPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 NHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWET
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 KKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 HLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 HLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 WQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 WQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 RIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWNVVTGESSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 RIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWNVVTGESSQ
1150 1160 1170 1180 1190 1200
1210 1220 1230
pF1KA0 TFYTNGTNLKKIHVSPDFKTYVTVDNLGIIYILQTLE
:::::::::::::::::::::::::::::.:::::::
CCDS55 TFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
1210 1220 1230
>>CCDS9069.1 APAF1 gene_id:317|Hs108|chr12 (1248 aa)
initn: 7757 init1: 7757 opt: 7765 Z-score: 6256.4 bits: 1169.8 E(32554): 0
Smith-Waterman score: 8341; 99.0% identity (99.1% similar) in 1248 aa overlap (1-1237:1-1248)
10 20 30 40 50 60
pF1KA0 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
10 20 30 40 50 60
70 80 90 100
pF1KA0 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSS-----------VRTVLCEGGVP
:::::::::::::::::::::::::::::::::::::: :::::::::::
CCDS90 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA0 KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA0 MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAV
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA0 SENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 SENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINK
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA0 KNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 KNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA0 LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA0 SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA0 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHH
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA0 STIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 STIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTS
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA0 SDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 SDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLT
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA0 EAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 EAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA0 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKD
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA0 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA0 LLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 LLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIK
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230
pF1KA0 WWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGIIYILQTLE
::::::::::::::::::::::::::::::::::::::::.:::::::
CCDS90 WWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
1210 1220 1230 1240
>>CCDS55863.1 APAF1 gene_id:317|Hs108|chr12 (1194 aa)
initn: 5473 init1: 5473 opt: 5646 Z-score: 4552.1 bits: 854.4 E(32554): 0
Smith-Waterman score: 7979; 96.4% identity (96.5% similar) in 1237 aa overlap (1-1237:1-1194)
10 20 30 40 50 60
pF1KA0 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSVRTVLCEGGVPQRPVVFVTRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSVRTVLCEGGVPQRPVVFVTRKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSIS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 DPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQ
::::::::::::::::::::::::::::::::
CCDS55 DPQEDMEVIVKCCSWSADGARIMVAAKNKIFL----------------------------
790 800 810
850 860 870 880 890 900
pF1KA0 NHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWET
:::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ---------------WNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWET
820 830 840 850
910 920 930 940 950 960
pF1KA0 KKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSP
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KA0 HLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 HLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWN
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KA0 WQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 WQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KA0 DISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEI
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KA0 RIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWNVVTGESSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 RIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWNVVTGESSQ
1100 1110 1120 1130 1140 1150
1210 1220 1230
pF1KA0 TFYTNGTNLKKIHVSPDFKTYVTVDNLGIIYILQTLE
:::::::::::::::::::::::::::::.:::::::
CCDS55 TFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
1160 1170 1180 1190
>>CCDS9070.1 APAF1 gene_id:317|Hs108|chr12 (1205 aa)
initn: 4857 init1: 4857 opt: 5038 Z-score: 4062.9 bits: 763.9 E(32554): 0
Smith-Waterman score: 7947; 95.6% identity (95.7% similar) in 1248 aa overlap (1-1237:1-1205)
10 20 30 40 50 60
pF1KA0 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
10 20 30 40 50 60
70 80 90 100
pF1KA0 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSS-----------VRTVLCEGGVP
:::::::::::::::::::::::::::::::::::::: :::::::::::
CCDS90 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA0 KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA0 MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAV
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA0 SENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 SENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINK
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA0 KNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 KNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA0 LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA0 SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA0 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHH
:::::::::::::::::::::::::::::::::::::::::::
CCDS90 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFL-----------------
790 800 810 820
830 840 850 860 870 880
pF1KA0 STIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTS
::::::::::::::::::::::::::::::::::
CCDS90 --------------------------WNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTS
830 840 850
890 900 910 920 930 940
pF1KA0 SDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 SDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLT
860 870 880 890 900 910
950 960 970 980 990 1000
pF1KA0 EAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 EAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS
920 930 940 950 960 970
1010 1020 1030 1040 1050 1060
pF1KA0 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKD
980 990 1000 1010 1020 1030
1070 1080 1090 1100 1110 1120
pF1KA0 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST
1040 1050 1060 1070 1080 1090
1130 1140 1150 1160 1170 1180
pF1KA0 LLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 LLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIK
1100 1110 1120 1130 1140 1150
1190 1200 1210 1220 1230
pF1KA0 WWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGIIYILQTLE
::::::::::::::::::::::::::::::::::::::::.:::::::
CCDS90 WWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
1160 1170 1180 1190 1200
>>CCDS9071.1 APAF1 gene_id:317|Hs108|chr12 (338 aa)
initn: 1406 init1: 1406 opt: 1421 Z-score: 1161.4 bits: 225.2 E(32554): 2.3e-58
Smith-Waterman score: 1997; 92.0% identity (93.8% similar) in 338 aa overlap (1-327:1-335)
10 20 30 40 50 60
pF1KA0 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
10 20 30 40 50 60
70 80 90 100
pF1KA0 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSS-----------VRTVLCEGGVP
:::::::::::::::::::::::::::::::::::::: :::::::::::
CCDS90 LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
:::::::::::::::::: .: ..: :. ..:
CCDS90 MKKADLPEQAHSIIKECK---VVERCHWGILTDLLHKWNQS
310 320 330
350 360 370 380 390 400
pF1KA0 YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
>>CCDS340.1 SNRNP40 gene_id:9410|Hs108|chr1 (357 aa)
initn: 280 init1: 125 opt: 368 Z-score: 314.0 bits: 68.4 E(32554): 3.6e-11
Smith-Waterman score: 368; 27.4% identity (60.7% similar) in 270 aa overlap (582-849:89-347)
560 570 580 590 600 610
pF1KA0 IVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHAC
: : : . : . : . :. ::..
CCDS34 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATL--KGHSGAVMELH
60 70 80 90 100 110
620 630 640 650 660 670
pF1KA0 FSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFST-DDRFIATCSVDKKV
.. ::. . : ..:::. :. .::::.. ..:.: . : : . ... : : : :
CCDS34 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV
120 130 140 150 160 170
680 690 700 710 720 730
pF1KA0 KIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFG
:.:. ..:. ... :: :...: ... .:. : .:.::: :.. :: :
CCDS34 KLWDIRKKAAIQTF-QNTYQVLAVTFNDTSDQII--SGGIDNDIKVWDLRQNKLTYTMRG
180 190 200 210 220 230
740 750 760 770 780 790
pF1KA0 HTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIV
:..::. .: . . : : . :.:...::. .. :: : :... .... .
CCDS34 HADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERC-VKIFQGNVHNFEKNL---L
240 250 260 270 280
800 810 820 830 840
pF1KA0 KCCSWSADGARIMVAAKNK-IFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALS
.: ::: ::..: ... .. ....: . .: .. :: ..:. : :.. . . : :
CCDS34 RC-SWSPDGSKIAAGSADRFVYVWDTTSRRILYKL-PGHAGSINEVAFHPDEPIIISASS
290 300 310 320 330 340
850 860 870 880 890 900
pF1KA0 QYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAV
CCDS34 DKRLYMGEIQ
350
1237 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 04:37:48 2016 done: Mon Nov 7 04:37:48 2016
Total Scan time: 4.340 Total Display time: 0.280
Function used was FASTA [36.3.4 Apr, 2011]