Result of FASTA (omim) for
pF1KSDB0050
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDB0050, 1290 aa
1>>>pF1KSDB0050 1290 - 1290 aa - 1290 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6107+/-0.000586; mu= 5.7497+/- 0.036
mean_var=287.4831+/-68.794, 0's: 0 Z-trim(110.8): 353 B-trim: 0 in 0/52
Lambda= 0.075643
statistics sampled from 18828 (19216) to 18828 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.568), E-opt: 0.2 (0.225), width: 16
Scan time: 11.620
The best scores are: opt bits E(85289)
NP_877963 (OMIM: 172420) 1-phosphatidylinositol 4, (1290) 8747 970.8 0
NP_002651 (OMIM: 172420) 1-phosphatidylinositol 4, (1291) 8735 969.5 0
XP_005260495 (OMIM: 172420) PREDICTED: 1-phosphati (1330) 7670 853.3 0
XP_011527167 (OMIM: 172420) PREDICTED: 1-phosphati (1151) 6455 720.7 1.4e-206
XP_011527169 (OMIM: 172420) PREDICTED: 1-phosphati ( 906) 6015 672.5 3.5e-192
NP_002652 (OMIM: 600220,614468,614878) 1-phosphati (1265) 1745 206.7 8.3e-52
XP_016861514 (OMIM: 614276) PREDICTED: inactive ph (1001) 721 94.8 3.1e-18
NP_055999 (OMIM: 614276) inactive phospholipase C- (1001) 721 94.8 3.1e-18
XP_006713136 (OMIM: 614276) PREDICTED: inactive ph (1022) 721 94.9 3.1e-18
NP_001137854 (OMIM: 614276) inactive phospholipase (1127) 721 94.9 3.3e-18
XP_016861512 (OMIM: 614276) PREDICTED: inactive ph (1127) 721 94.9 3.3e-18
XP_016861513 (OMIM: 614276) PREDICTED: inactive ph (1127) 721 94.9 3.3e-18
XP_016861511 (OMIM: 614276) PREDICTED: inactive ph (1127) 721 94.9 3.3e-18
NP_001289942 (OMIM: 612836) 1-phosphatidylinositol (1019) 696 92.1 2.1e-17
XP_016858363 (OMIM: 612836) PREDICTED: 1-phosphati (1094) 696 92.2 2.2e-17
NP_001289941 (OMIM: 612836) 1-phosphatidylinositol (1129) 696 92.2 2.2e-17
NP_055453 (OMIM: 612836) 1-phosphatidylinositol 4, (1416) 696 92.3 2.6e-17
XP_016858362 (OMIM: 612836) PREDICTED: 1-phosphati (1475) 696 92.3 2.6e-17
XP_016858361 (OMIM: 612836) PREDICTED: 1-phosphati (1511) 696 92.3 2.7e-17
XP_011540757 (OMIM: 612836) PREDICTED: 1-phosphati (1580) 696 92.3 2.8e-17
XP_011540758 (OMIM: 612836) PREDICTED: 1-phosphati (1580) 696 92.3 2.8e-17
NP_001124433 (OMIM: 612835) 1-phosphatidylinositol (1002) 692 91.7 2.8e-17
XP_016861418 (OMIM: 612835) PREDICTED: 1-phosphati (1002) 692 91.7 2.8e-17
XP_016861417 (OMIM: 612835) PREDICTED: 1-phosphati (1014) 692 91.7 2.8e-17
XP_011510869 (OMIM: 612835) PREDICTED: 1-phosphati (1014) 692 91.7 2.8e-17
XP_016861416 (OMIM: 612835) PREDICTED: 1-phosphati (1021) 692 91.7 2.8e-17
XP_016858360 (OMIM: 612836) PREDICTED: 1-phosphati (1670) 696 92.4 2.9e-17
XP_016858359 (OMIM: 612836) PREDICTED: 1-phosphati (1678) 696 92.4 2.9e-17
NP_055811 (OMIM: 612835) 1-phosphatidylinositol 4, (1655) 692 91.9 3.8e-17
XP_005247296 (OMIM: 612835) PREDICTED: 1-phosphati (1673) 692 91.9 3.9e-17
XP_011510867 (OMIM: 612835) PREDICTED: 1-phosphati (1675) 692 91.9 3.9e-17
XP_011510868 (OMIM: 612835) PREDICTED: 1-phosphati (1675) 692 91.9 3.9e-17
XP_016861415 (OMIM: 612835) PREDICTED: 1-phosphati (1675) 692 91.9 3.9e-17
XP_016861413 (OMIM: 612835) PREDICTED: 1-phosphati (1684) 692 91.9 3.9e-17
XP_011510866 (OMIM: 612835) PREDICTED: 1-phosphati (1685) 692 91.9 3.9e-17
NP_001124432 (OMIM: 612835) 1-phosphatidylinositol (1693) 692 91.9 3.9e-17
XP_016861412 (OMIM: 612835) PREDICTED: 1-phosphati (1704) 692 91.9 3.9e-17
XP_005247295 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 692 91.9 3.9e-17
XP_011510863 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 692 91.9 3.9e-17
XP_011510864 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 692 91.9 3.9e-17
XP_011510862 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 692 91.9 3.9e-17
XP_016861414 (OMIM: 612835) PREDICTED: 1-phosphati (1681) 691 91.8 4.2e-17
NP_588614 (OMIM: 608795) 1-phosphatidylinositol 4, ( 789) 665 88.6 1.8e-16
XP_016871801 (OMIM: 608414,610725) PREDICTED: 1-ph (1978) 660 88.5 4.9e-16
NP_001159451 (OMIM: 608414,610725) 1-phosphatidyli (1994) 660 88.5 4.9e-16
NP_001275918 (OMIM: 608414,610725) 1-phosphatidyli (2286) 660 88.6 5.3e-16
NP_057425 (OMIM: 608414,610725) 1-phosphatidylinos (2302) 660 88.6 5.4e-16
XP_016860608 (OMIM: 605939) PREDICTED: 1-phosphati ( 675) 642 86.0 9.4e-16
XP_016860607 (OMIM: 605939) PREDICTED: 1-phosphati ( 716) 642 86.1 9.8e-16
NP_116115 (OMIM: 605939) 1-phosphatidylinositol 4, ( 762) 642 86.1 1e-15
>>NP_877963 (OMIM: 172420) 1-phosphatidylinositol 4,5-bi (1290 aa)
initn: 8747 init1: 8747 opt: 8747 Z-score: 5180.7 bits: 970.8 E(85289): 0
Smith-Waterman score: 8747; 99.9% identity (99.9% similar) in 1290 aa overlap (1-1290:1-1290)
10 20 30 40 50 60
pF1KSD MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 SLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD GFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLW
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_877 GFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLW
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD FPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 FPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD SLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 SLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVW
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD PAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 PAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD ELASLLIKIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 ELASLLIKIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDF
1210 1220 1230 1240 1250 1260
1270 1280 1290
pF1KSD RISQEHLADHFDSRERRAPRRTRVNGDNRL
::::::::::::::::::::::::::::::
NP_877 RISQEHLADHFDSRERRAPRRTRVNGDNRL
1270 1280 1290
>>NP_002651 (OMIM: 172420) 1-phosphatidylinositol 4,5-bi (1291 aa)
initn: 8388 init1: 8237 opt: 8735 Z-score: 5173.6 bits: 969.5 E(85289): 0
Smith-Waterman score: 8735; 99.8% identity (99.8% similar) in 1291 aa overlap (1-1290:1-1291)
10 20 30 40 50 60
pF1KSD MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD GFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLW
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_002 GFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLW
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD FPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD SLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVW
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD PAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250
pF1KSD ELASLLIKIDIFPAK-ENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFED
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_002 ELASLLIKIDIFPAKQENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFED
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290
pF1KSD FRISQEHLADHFDSRERRAPRRTRVNGDNRL
:::::::::::::::::::::::::::::::
NP_002 FRISQEHLADHFDSRERRAPRRTRVNGDNRL
1270 1280 1290
>>XP_005260495 (OMIM: 172420) PREDICTED: 1-phosphatidyli (1330 aa)
initn: 8223 init1: 7670 opt: 7670 Z-score: 4545.4 bits: 853.3 E(85289): 0
Smith-Waterman score: 8593; 96.9% identity (96.9% similar) in 1322 aa overlap (1-1282:1-1322)
10 20 30 40 50 60
pF1KSD MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD GFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLW
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_005 GFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLW
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD FPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KSD SLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFV---------
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVGQSVFPVIL
1090 1100 1110 1120 1130 1140
1140 1150 1160
pF1KSD ------------------------------VDNGLNPVWPAKPFHFQISNPEFAFLRFVV
::::::::::::::::::::::::::::::
XP_005 LILLGHCKPLPTSHPILSHGDLKPFVVAFTVDNGLNPVWPAKPFHFQISNPEFAFLRFVV
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210 1220
pF1KSD YEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAK-ENGDL
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_005 YEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKQENGDL
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KSD SPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDFRISQEHLADHFDSRERRAPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDFRISQEHLADHFDSRERRAPR
1270 1280 1290 1300 1310 1320
1290
pF1KSD RTRVNGDNRL
::
XP_005 RTRVNGDNRL
1330
>>XP_011527167 (OMIM: 172420) PREDICTED: 1-phosphatidyli (1151 aa)
initn: 7008 init1: 6455 opt: 6455 Z-score: 3829.5 bits: 720.7 E(85289): 1.4e-206
Smith-Waterman score: 7378; 96.4% identity (96.4% similar) in 1143 aa overlap (180-1282:1-1143)
150 160 170 180 190 200
pF1KSD PLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDIT
::::::::::::::::::::::::::::::
XP_011 MLSQVNYRVPNMRFLRERLTDLEQRSGDIT
10 20 30
210 220 230 240 250 260
pF1KSD YGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVD
40 50 60 70 80 90
270 280 290 300 310 320
pF1KSD RLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHY
100 110 120 130 140 150
330 340 350 360 370 380
pF1KSD WISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIK
160 170 180 190 200 210
390 400 410 420 430 440
pF1KSD FSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGL
220 230 240 250 260 270
450 460 470 480 490 500
pF1KSD PSPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHY
280 290 300 310 320 330
510 520 530 540 550 560
pF1KSD FVLTSSKIYYSEETSSDQGNEDEEEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVLTSSKIYYSEETSSDQGNEDEEEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLL
340 350 360 370 380 390
570 580 590 600 610 620
pF1KSD TEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVF
400 410 420 430 440 450
630 640 650 660 670 680
pF1KSD DSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDG
460 470 480 490 500 510
690 700 710 720 730 740
pF1KSD AFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRK
520 530 540 550 560 570
750 760 770 780 790 800
pF1KSD MKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDE
580 590 600 610 620 630
810 820 830 840 850 860
pF1KSD LTFTKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLG
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLG
640 650 660 670 680 690
870 880 890 900 910 920
pF1KSD DLLRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREV
700 710 720 730 740 750
930 940 950 960 970 980
pF1KSD AQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAE
760 770 780 790 800 810
990 1000 1010 1020 1030 1040
pF1KSD KYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQM
820 830 840 850 860 870
1050 1060 1070 1080 1090 1100
pF1KSD NQALFMTGRHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAISIEVLGARHLPKNGRGIVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQALFMTGRHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAISIEVLGARHLPKNGRGIVC
880 890 900 910 920 930
1110 1120 1130
pF1KSD PFVEIEVAGAEYDSTKQKTEFV--------------------------------------
::::::::::::::::::::::
XP_011 PFVEIEVAGAEYDSTKQKTEFVGQSVFPVILLILLGHCKPLPTSHPILSHGDLKPFVVAF
940 950 960 970 980 990
1140 1150 1160 1170 1180 1190
pF1KSD -VDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAV
1000 1010 1020 1030 1040 1050
1200 1210 1220 1230 1240
pF1KSD PLKNNYSEDLELASLLIKIDIFPAK-ENGDLSPFSGTSLRERGSDASGQLFHGRAREGSF
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 PLKNNYSEDLELASLLIKIDIFPAKQENGDLSPFSGTSLRERGSDASGQLFHGRAREGSF
1060 1070 1080 1090 1100 1110
1250 1260 1270 1280 1290
pF1KSD ESRYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL
:::::::::::::::::::::::::::::::::
XP_011 ESRYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL
1120 1130 1140 1150
>>XP_011527169 (OMIM: 172420) PREDICTED: 1-phosphatidyli (906 aa)
initn: 6163 init1: 6012 opt: 6015 Z-score: 3571.2 bits: 672.5 E(85289): 3.5e-192
Smith-Waterman score: 6015; 99.4% identity (99.4% similar) in 891 aa overlap (1-889:1-891)
10 20 30 40 50 60
pF1KSD MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD GFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLW
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_011 GFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLW
790 800 810 820 830 840
850 860 870 880 890
pF1KSD FPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIR--PEGKNNRLFVFS
:::::::::::::::::::::::::::::::::::::::::::: : : :
XP_011 FPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAWRRWPTGPWMLLPTHR
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD ISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVV
XP_011 RSCRTG
>>NP_002652 (OMIM: 600220,614468,614878) 1-phosphatidyli (1265 aa)
initn: 3330 init1: 1133 opt: 1745 Z-score: 1051.1 bits: 206.7 E(85289): 8.3e-52
Smith-Waterman score: 4203; 50.9% identity (76.9% similar) in 1279 aa overlap (18-1285:11-1259)
10 20 30 40 50 60
pF1KSD MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
.. : .. :.::.:::::.: .:: :::.: :: .::::.
NP_002 MSTTVNVDSLAEYEKSQIKRALELGTVMTVFSFRKST-PERRTVQVIMETRQV
10 20 30 40 50
70 80 90 100 110 120
pF1KSD TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
.::. :::::: .:: :::::::::.:.::.: . : : .. ::.:::: .: :.::
NP_002 AWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAK---AVRQKEDCCFTILYGTQFVLSTL
60 70 80 90 100
130 140 150 160 170
pF1KSD SLQATS-EDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKN
:: : : :: :: :..:: : .....: :: :: :::::.::::..:.. :: ..::.
NP_002 SLAADSKEDAVN-WLSGLKILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKT
110 120 130 140 150 160
180 190 200 210 220 230
pF1KSD MLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEAST--
.: .:..: . .::....... .. .... :: .:..::. ::.. : . :.
NP_002 ILPLINFKVSSAKFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVF
170 180 190 200 210 220
240 250 260 270 280 290
pF1KSD -LRAGERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLD
: .::. : : .::.::. : : :: : .:.: : .:. : .:: ::..:.:
NP_002 ILGNTDRPDASAVYLHDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KSD EFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARC
::.:.:::.:::.:. . ::: . ::::::::::::::::::::::. :::: ::: ::
NP_002 EFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRC
290 300 310 320 330 340
360 370 380 390 400 410
pF1KSD LRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDH
:::::::::::::::::: :::::: : ::::::.::...::.::::.: .:::::::.:
NP_002 LRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEH
350 360 370 380 390 400
420 430 440 450 460 470
pF1KSD CSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVP
::. :::.::. ::.:.:: :::::.: ::: ::::.::..::.::::::. . .:
NP_002 CSVEQQRHMAKAFKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRG---DVD
410 420 430 440 450 460
480 490 500 510 520 530
pF1KSD TSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPK
..: :. .. ..: ::. : ....: :: .....:. .:.. .: : :: :.
NP_002 VNM---EDKKDEHKQQGELYMWDSIDQKWTRHYCAIADAKLSFSDDI--EQTME-EEVPQ
470 480 490 500 510
540 550 560 570 580 590
pF1KSD EVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYT
.. :::: .::::: :. . : ::.:: :::.:::. ::.::::::::: .:::
NP_002 DIPP-TELHFGEKWFHKKV----EKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYT
520 530 540 550 560 570
600 610 620 630 640 650
pF1KSD LSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEP
:::::.:.::::::.: ...:: :..:::::.:.:.: :: ::... ::: :::.::..:
NP_002 LSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDP
580 590 600 610 620 630
660 670 680 690 700 710
pF1KSD VPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCR
::. : :::: ::. ::.:..:: ::::.:::::::.:::. .::::.:::.::.::::
NP_002 VPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCR
640 650 660 670 680 690
720 730 740 750 760 770
pF1KSD VQQEGQTVMLGNSE-FDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALY
....:. .::.: :.:::.:.:::::: :::::.::::.. : ::. . : : ..::
NP_002 INRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNM-ERDINSLY
700 710 720 730 740 750
780 790 800 810 820 830
pF1KSD EGRNPGFYV---EANP-MPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRG
. .:: : :: :: . .::::.::::.: :::.: ..:.:.:: :. ::::.:
NP_002 DVSR--MYVDPSEINPSMP--QRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKG
760 770 780 790 800
840 850 860 870 880 890
pF1KSD DYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKN
::: . : .:::::::. .. . .: .... :..:::.: ::.::. . ... :.:::
NP_002 DYGTRIQQYFPSNYVED-ISTADFEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKN
810 820 830 840 850 860
900 910 920 930 940 950
pF1KSD NRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIAL
.. ::: . . . .. :.: ::: .: ..:::.. :.. .. : :. ..::.
NP_002 QKSFVFILEPKQQGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAI
870 880 890 900 910 920
960 970 980 990 1000 1010
pF1KSD ELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRI
:::.:::::.:. .. : . : .:.. :: ::::.. . . : .:.::. :.:.
NP_002 ELSDLVVYCKPT--SKTKDNLENPDFREIRSFVETKADSII-RQKPVDLLKYNQKGLTRV
930 940 950 960 970 980
1020 1030 1040 1050 1060 1070
pF1KSD YPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRD
::::::.:::::::. .:.::::.::::::: :: ::::.::: . . :::::: .::
NP_002 YPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRT
990 1000 1010 1020 1030 1040
1080 1090 1100 1110 1120 1130
pF1KSD EAFDPFDKSSLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFV
: .::. : : . .....::::::::: ::.:.:::::.:. :::::..: :: :
NP_002 EKYDPMPPESQRKIL-MTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVV
1050 1060 1070 1080 1090 1100
1140 1150 1160 1170 1180
pF1KSD VDNGLNPVW-PAKP-FHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRA
::::.:.: :.. :.: .:..::::::::::::::: ::::.::.:.:..:.:.:.
NP_002 NDNGLSPIWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRS
1110 1120 1130 1140 1150 1160
1190 1200 1210 1220 1230 1240
pF1KSD VPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRAREGSF
:::::.::::.::::::. .. :. :. . : .::.: . ..::: ....
NP_002 VPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLR
1170 1180 1190 1200 1210 1220
1250 1260 1270 1280 1290
pF1KSD ESRYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL
.. . ..: .....: . .. ..: :. ::.
NP_002 NANRDALVKEFSVNENQLQLYQEKCNKRL-REKRVSNSKFYS
1230 1240 1250 1260
>>XP_016861514 (OMIM: 614276) PREDICTED: inactive phosph (1001 aa)
initn: 1058 init1: 571 opt: 721 Z-score: 448.4 bits: 94.8 E(85289): 3.1e-18
Smith-Waterman score: 758; 31.6% identity (61.6% similar) in 474 aa overlap (41-502:27-480)
20 30 40 50 60 70
pF1KSD GCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIE
....: .. : . . ... : . :
XP_016 MPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSE
10 20 30 40 50
80 90 100 110 120
pF1KSD GA-IDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHC-FVILYGMEFRLKTLSLQATSED
: :::. :::.: ::.. : .. . . : : ..:: .. ..:.: :.: :
XP_016 KAKIDIKSIKEVRTGKNT---DIFRSNGISDQISEDCAFSVIYGENY--ESLDLVANSAD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD EVNMWIKGLTWLME------DTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNMLS
.:.:. :: .:. : :.. . :. ..: .: . .:. . . .
XP_016 VANIWVTGLRYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNAVQCIR
120 130 140 150 160 170
190 200 210 220 230
pF1KSD QVN--YRVPNMRFLRERLTDLEQRSG-DITYGQFAQLYRSLMYSAQKTMDLPFLEASTLR
..: .. .... ..: ....: ..: .: .... : . . :: ..
XP_016 NLNPGLKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELCTRPE----IYFL---LVQ
180 190 200 210 220
240 250 260 270 280 290
pF1KSD AGERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEP-YFFLDEF
. :. .. ....:: :: ..... :.. .. .: .: .: .. .: :
XP_016 FSSNKEF--LDTKDLMMFLEAEQGVAHINEEISL-EIIHKY--EPSKEGQEKGWLSIDGF
230 240 250 260 270
300 310 320 330 340 350
pF1KSD VTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLR
...:.: . ... . :: : :..:::::.:.::::::: ::: . :.. .: : :.
XP_016 TNYLMSPDCYIFDPEHKKVCQD-MKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALK
280 290 300 310 320 330
360 370 380 390 400 410
pF1KSD MGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCS
:::: .::: :::::. :::: :::.:..: : .:. :...:: :::::.:: .:.:::
XP_016 MGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCS
340 350 360 370 380 390
420 430 440 450 460 470
pF1KSD IAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTS
: ::. :.:..::.::: : : .. . ::::. :: ::::: :::. : : .
XP_016 IKQQKVMVQHMKKLLGDKLYTTSPNVEESYLPSPDVLKGKILIKAKKLS--SNCSGVEGD
400 410 420 430 440 450
480 490 500 510 520 530
pF1KSD MMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEV
. .. : . : .:.: :
XP_016 VTDEDEGAEMSQRMGKENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKY
460 470 480 490 500 510
>--
initn: 468 init1: 254 opt: 667 Z-score: 416.5 bits: 89.0 E(85289): 1.8e-16
Smith-Waterman score: 667; 35.9% identity (66.5% similar) in 340 aa overlap (945-1275:484-809)
920 930 940 950 960 970
pF1KSD SQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTER
.: .. :::::: :. : : : ... .
XP_016 EGDVTDEDEGAEMSQRMGKENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQV
460 470 480 490 500 510
980 990 1000 1010 1020 1030
pF1KSD ACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQ
: .. :: :. : ::.:. : :..::. :.:..:. .:.::::..: .: :: :
XP_016 QKYWEVCSFNEVLASKYANENPGD-FVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQ
520 530 540 550 560 570
1040 1050 1060 1070 1080 1090
pF1KSD LVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEA--FDPFDKSSLRGLEPCAISI
.::.::::: :..: . : . .:::::.:. ::.:. :. :.:. :. : . :
XP_016 IVAMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHI
580 590 600 610 620 630
1100 1110 1120 1130 1140
pF1KSD EVLGARHLPK-NGRG----IVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHF
........:: .: : .: :.: .:. : : ..:.:. : .:: :.. . :.:
XP_016 KIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVHQNGDAPIFD-ESFEF
640 650 660 670 680 690
1150 1160 1170 1180 1190 1200
pF1KSD QISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLI
::. ::.:..:::: ..:...:. :..: :.: . :.:::: :::.. .: : :::..
XP_016 QINLPELAMVRFVVLDDDYIGDE-FIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFV
700 710 720 730 740 750
1210 1220 1230 1240 1250 1260
pF1KSD KIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRARE-GSFESRYQQPFED-FRISQE
.. : ...: : :.: .:. ..:: .:... . . .. :. .:
XP_016 HVAI-TNRRGGGKPHKRGLSVR-KGK---------KSREYASLRTLWIKTVDEVFKNAQP
760 770 780 790
1270 1280 1290
pF1KSD HLADHFDSRERRAPRRTRVNGDNRL
. : : ::
XP_016 PIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEQYP
800 810 820 830 840 850
>>NP_055999 (OMIM: 614276) inactive phospholipase C-like (1001 aa)
initn: 1058 init1: 571 opt: 721 Z-score: 448.4 bits: 94.8 E(85289): 3.1e-18
Smith-Waterman score: 758; 31.6% identity (61.6% similar) in 474 aa overlap (41-502:27-480)
20 30 40 50 60 70
pF1KSD GCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIE
....: .. : . . ... : . :
NP_055 MPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSE
10 20 30 40 50
80 90 100 110 120
pF1KSD GA-IDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHC-FVILYGMEFRLKTLSLQATSED
: :::. :::.: ::.. : .. . . : : ..:: .. ..:.: :.: :
NP_055 KAKIDIKSIKEVRTGKNT---DIFRSNGISDQISEDCAFSVIYGENY--ESLDLVANSAD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD EVNMWIKGLTWLME------DTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNMLS
.:.:. :: .:. : :.. . :. ..: .: . .:. . . .
NP_055 VANIWVTGLRYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNAVQCIR
120 130 140 150 160 170
190 200 210 220 230
pF1KSD QVN--YRVPNMRFLRERLTDLEQRSG-DITYGQFAQLYRSLMYSAQKTMDLPFLEASTLR
..: .. .... ..: ....: ..: .: .... : . . :: ..
NP_055 NLNPGLKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELCTRPE----IYFL---LVQ
180 190 200 210 220
240 250 260 270 280 290
pF1KSD AGERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEP-YFFLDEF
. :. .. ....:: :: ..... :.. .. .: .: .: .. .: :
NP_055 FSSNKEF--LDTKDLMMFLEAEQGVAHINEEISL-EIIHKY--EPSKEGQEKGWLSIDGF
230 240 250 260 270
300 310 320 330 340 350
pF1KSD VTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLR
...:.: . ... . :: : :..:::::.:.::::::: ::: . :.. .: : :.
NP_055 TNYLMSPDCYIFDPEHKKVCQD-MKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALK
280 290 300 310 320 330
360 370 380 390 400 410
pF1KSD MGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCS
:::: .::: :::::. :::: :::.:..: : .:. :...:: :::::.:: .:.:::
NP_055 MGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCS
340 350 360 370 380 390
420 430 440 450 460 470
pF1KSD IAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTS
: ::. :.:..::.::: : : .. . ::::. :: ::::: :::. : : .
NP_055 IKQQKVMVQHMKKLLGDKLYTTSPNVEESYLPSPDVLKGKILIKAKKLS--SNCSGVEGD
400 410 420 430 440 450
480 490 500 510 520 530
pF1KSD MMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEV
. .. : . : .:.: :
NP_055 VTDEDEGAEMSQRMGKENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKY
460 470 480 490 500 510
>--
initn: 468 init1: 254 opt: 667 Z-score: 416.5 bits: 89.0 E(85289): 1.8e-16
Smith-Waterman score: 667; 35.9% identity (66.5% similar) in 340 aa overlap (945-1275:484-809)
920 930 940 950 960 970
pF1KSD SQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTER
.: .. :::::: :. : : : ... .
NP_055 EGDVTDEDEGAEMSQRMGKENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQV
460 470 480 490 500 510
980 990 1000 1010 1020 1030
pF1KSD ACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQ
: .. :: :. : ::.:. : :..::. :.:..:. .:.::::..: .: :: :
NP_055 QKYWEVCSFNEVLASKYANENPGD-FVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQ
520 530 540 550 560 570
1040 1050 1060 1070 1080 1090
pF1KSD LVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEA--FDPFDKSSLRGLEPCAISI
.::.::::: :..: . : . .:::::.:. ::.:. :. :.:. :. : . :
NP_055 IVAMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHI
580 590 600 610 620 630
1100 1110 1120 1130 1140
pF1KSD EVLGARHLPK-NGRG----IVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHF
........:: .: : .: :.: .:. : : ..:.:. : .:: :.. . :.:
NP_055 KIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVHQNGDAPIFD-ESFEF
640 650 660 670 680 690
1150 1160 1170 1180 1190 1200
pF1KSD QISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLI
::. ::.:..:::: ..:...:. :..: :.: . :.:::: :::.. .: : :::..
NP_055 QINLPELAMVRFVVLDDDYIGDE-FIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFV
700 710 720 730 740 750
1210 1220 1230 1240 1250 1260
pF1KSD KIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRARE-GSFESRYQQPFED-FRISQE
.. : ...: : :.: .:. ..:: .:... . . .. :. .:
NP_055 HVAI-TNRRGGGKPHKRGLSVR-KGK---------KSREYASLRTLWIKTVDEVFKNAQP
760 770 780 790
1270 1280 1290
pF1KSD HLADHFDSRERRAPRRTRVNGDNRL
. : : ::
NP_055 PIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEQYP
800 810 820 830 840 850
>>XP_006713136 (OMIM: 614276) PREDICTED: inactive phosph (1022 aa)
initn: 1058 init1: 571 opt: 721 Z-score: 448.3 bits: 94.9 E(85289): 3.1e-18
Smith-Waterman score: 758; 31.6% identity (61.6% similar) in 474 aa overlap (41-502:48-501)
20 30 40 50 60 70
pF1KSD GCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIE
....: .. : . . ... : . :
XP_006 SFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSE
20 30 40 50 60 70
80 90 100 110 120
pF1KSD GA-IDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHC-FVILYGMEFRLKTLSLQATSED
: :::. :::.: ::.. : .. . . : : ..:: .. ..:.: :.: :
XP_006 KAKIDIKSIKEVRTGKNT---DIFRSNGISDQISEDCAFSVIYGENY--ESLDLVANSAD
80 90 100 110 120 130
130 140 150 160 170 180
pF1KSD EVNMWIKGLTWLME------DTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNMLS
.:.:. :: .:. : :.. . :. ..: .: . .:. . . .
XP_006 VANIWVTGLRYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNAVQCIR
140 150 160 170 180 190
190 200 210 220 230
pF1KSD QVN--YRVPNMRFLRERLTDLEQRSG-DITYGQFAQLYRSLMYSAQKTMDLPFLEASTLR
..: .. .... ..: ....: ..: .: .... : . . :: ..
XP_006 NLNPGLKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELCTRPE----IYFL---LVQ
200 210 220 230 240
240 250 260 270 280 290
pF1KSD AGERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEP-YFFLDEF
. :. .. ....:: :: ..... :.. .. .: .: .: .. .: :
XP_006 FSSNKEF--LDTKDLMMFLEAEQGVAHINEEISL-EIIHKY--EPSKEGQEKGWLSIDGF
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD VTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLR
...:.: . ... . :: : :..:::::.:.::::::: ::: . :.. .: : :.
XP_006 TNYLMSPDCYIFDPEHKKVCQD-MKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALK
310 320 330 340 350
360 370 380 390 400 410
pF1KSD MGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCS
:::: .::: :::::. :::: :::.:..: : .:. :...:: :::::.:: .:.:::
XP_006 MGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCS
360 370 380 390 400 410
420 430 440 450 460 470
pF1KSD IAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTS
: ::. :.:..::.::: : : .. . ::::. :: ::::: :::. : : .
XP_006 IKQQKVMVQHMKKLLGDKLYTTSPNVEESYLPSPDVLKGKILIKAKKLS--SNCSGVEGD
420 430 440 450 460 470
480 490 500 510 520 530
pF1KSD MMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEV
. .. : . : .:.: :
XP_006 VTDEDEGAEMSQRMGKENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKY
480 490 500 510 520 530
>--
initn: 468 init1: 254 opt: 667 Z-score: 416.4 bits: 89.0 E(85289): 1.9e-16
Smith-Waterman score: 667; 35.9% identity (66.5% similar) in 340 aa overlap (945-1275:505-830)
920 930 940 950 960 970
pF1KSD SQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTER
.: .. :::::: :. : : : ... .
XP_006 EGDVTDEDEGAEMSQRMGKENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQV
480 490 500 510 520 530
980 990 1000 1010 1020 1030
pF1KSD ACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQ
: .. :: :. : ::.:. : :..::. :.:..:. .:.::::..: .: :: :
XP_006 QKYWEVCSFNEVLASKYANENPGD-FVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQ
540 550 560 570 580 590
1040 1050 1060 1070 1080 1090
pF1KSD LVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEA--FDPFDKSSLRGLEPCAISI
.::.::::: :..: . : . .:::::.:. ::.:. :. :.:. :. : . :
XP_006 IVAMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHI
600 610 620 630 640 650
1100 1110 1120 1130 1140
pF1KSD EVLGARHLPK-NGRG----IVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHF
........:: .: : .: :.: .:. : : ..:.:. : .:: :.. . :.:
XP_006 KIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVHQNGDAPIFD-ESFEF
660 670 680 690 700 710
1150 1160 1170 1180 1190 1200
pF1KSD QISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLI
::. ::.:..:::: ..:...:. :..: :.: . :.:::: :::.. .: : :::..
XP_006 QINLPELAMVRFVVLDDDYIGDE-FIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFV
720 730 740 750 760 770
1210 1220 1230 1240 1250 1260
pF1KSD KIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRARE-GSFESRYQQPFED-FRISQE
.. : ...: : :.: .:. ..:: .:... . . .. :. .:
XP_006 HVAI-TNRRGGGKPHKRGLSVR-KGK---------KSREYASLRTLWIKTVDEVFKNAQP
780 790 800 810 820
1270 1280 1290
pF1KSD HLADHFDSRERRAPRRTRVNGDNRL
. : : ::
XP_006 PIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEQYP
830 840 850 860 870 880
>>NP_001137854 (OMIM: 614276) inactive phospholipase C-l (1127 aa)
initn: 1058 init1: 571 opt: 721 Z-score: 447.8 bits: 94.9 E(85289): 3.3e-18
Smith-Waterman score: 758; 31.6% identity (61.6% similar) in 474 aa overlap (41-502:153-606)
20 30 40 50 60 70
pF1KSD GCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIE
....: .. : . . ... : . :
NP_001 SFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSE
130 140 150 160 170 180
80 90 100 110 120
pF1KSD GA-IDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHC-FVILYGMEFRLKTLSLQATSED
: :::. :::.: ::.. : .. . . : : ..:: .. ..:.: :.: :
NP_001 KAKIDIKSIKEVRTGKNT---DIFRSNGISDQISEDCAFSVIYGENY--ESLDLVANSAD
190 200 210 220 230
130 140 150 160 170 180
pF1KSD EVNMWIKGLTWLME------DTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNMLS
.:.:. :: .:. : :.. . :. ..: .: . .:. . . .
NP_001 VANIWVTGLRYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNAVQCIR
240 250 260 270 280 290
190 200 210 220 230
pF1KSD QVN--YRVPNMRFLRERLTDLEQRSG-DITYGQFAQLYRSLMYSAQKTMDLPFLEASTLR
..: .. .... ..: ....: ..: .: .... : . . :: ..
NP_001 NLNPGLKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELCTRPE----IYFL---LVQ
300 310 320 330 340 350
240 250 260 270 280 290
pF1KSD AGERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEP-YFFLDEF
. :. .. ....:: :: ..... :.. .. .: .: .: .. .: :
NP_001 FSSNKEF--LDTKDLMMFLEAEQGVAHINEEISL-EIIHKY--EPSKEGQEKGWLSIDGF
360 370 380 390 400
300 310 320 330 340 350
pF1KSD VTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLR
...:.: . ... . :: : :..:::::.:.::::::: ::: . :.. .: : :.
NP_001 TNYLMSPDCYIFDPEHKKVCQD-MKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALK
410 420 430 440 450 460
360 370 380 390 400 410
pF1KSD MGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCS
:::: .::: :::::. :::: :::.:..: : .:. :...:: :::::.:: .:.:::
NP_001 MGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCS
470 480 490 500 510 520
420 430 440 450 460 470
pF1KSD IAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTS
: ::. :.:..::.::: : : .. . ::::. :: ::::: :::. : : .
NP_001 IKQQKVMVQHMKKLLGDKLYTTSPNVEESYLPSPDVLKGKILIKAKKLS--SNCSGVEGD
530 540 550 560 570 580
480 490 500 510 520 530
pF1KSD MMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEV
. .. : . : .:.: :
NP_001 VTDEDEGAEMSQRMGKENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKY
590 600 610 620 630 640
>--
initn: 468 init1: 254 opt: 667 Z-score: 415.9 bits: 89.0 E(85289): 2e-16
Smith-Waterman score: 667; 35.9% identity (66.5% similar) in 340 aa overlap (945-1275:610-935)
920 930 940 950 960 970
pF1KSD SQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTER
.: .. :::::: :. : : : ... .
NP_001 EGDVTDEDEGAEMSQRMGKENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQV
580 590 600 610 620 630
980 990 1000 1010 1020 1030
pF1KSD ACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQ
: .. :: :. : ::.:. : :..::. :.:..:. .:.::::..: .: :: :
NP_001 QKYWEVCSFNEVLASKYANENPGD-FVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQ
640 650 660 670 680 690
1040 1050 1060 1070 1080 1090
pF1KSD LVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEA--FDPFDKSSLRGLEPCAISI
.::.::::: :..: . : . .:::::.:. ::.:. :. :.:. :. : . :
NP_001 IVAMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHI
700 710 720 730 740 750
1100 1110 1120 1130 1140
pF1KSD EVLGARHLPK-NGRG----IVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHF
........:: .: : .: :.: .:. : : ..:.:. : .:: :.. . :.:
NP_001 KIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVHQNGDAPIFD-ESFEF
760 770 780 790 800 810
1150 1160 1170 1180 1190 1200
pF1KSD QISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLI
::. ::.:..:::: ..:...:. :..: :.: . :.:::: :::.. .: : :::..
NP_001 QINLPELAMVRFVVLDDDYIGDE-FIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFV
820 830 840 850 860 870
1210 1220 1230 1240 1250 1260
pF1KSD KIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRARE-GSFESRYQQPFED-FRISQE
.. : ...: : :.: .:. ..:: .:... . . .. :. .:
NP_001 HVAI-TNRRGGGKPHKRGLSVR-KGK---------KSREYASLRTLWIKTVDEVFKNAQP
880 890 900 910 920
1270 1280 1290
pF1KSD HLADHFDSRERRAPRRTRVNGDNRL
. : : ::
NP_001 PIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEQYP
930 940 950 960 970 980
1290 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:19:03 2016 done: Thu Nov 3 19:19:05 2016
Total Scan time: 11.620 Total Display time: 0.570
Function used was FASTA [36.3.4 Apr, 2011]