Result of FASTA (omim) for
pF1KSDA0952
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0952, 522 aa
1>>>pF1KSDA0952 522 - 522 aa - 522 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6871+/-0.000407; mu= 16.4416+/- 0.025
mean_var=77.7811+/-16.232, 0's: 0 Z-trim(112.4): 206 B-trim: 524 in 1/53
Lambda= 0.145424
statistics sampled from 21018 (21276) to 21018 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.249), width: 16
Scan time: 9.480
The best scores are: opt bits E(85289)
NP_055777 (OMIM: 615566) BTB/POZ domain-containing ( 522) 3470 738.0 1.6e-212
NP_852108 (OMIM: 615566) BTB/POZ domain-containing ( 565) 3338 710.3 3.7e-204
XP_016883218 (OMIM: 615566) PREDICTED: BTB/POZ dom ( 461) 3086 657.4 2.6e-188
NP_001269479 (OMIM: 615566) BTB/POZ domain-contain ( 461) 3086 657.4 2.6e-188
NP_001269480 (OMIM: 615566) BTB/POZ domain-contain ( 461) 3086 657.4 2.6e-188
XP_016883217 (OMIM: 615566) PREDICTED: BTB/POZ dom ( 461) 3086 657.4 2.6e-188
NP_001269481 (OMIM: 615566) BTB/POZ domain-contain ( 371) 2468 527.7 2.3e-149
XP_016883219 (OMIM: 615566) PREDICTED: BTB/POZ dom ( 371) 2468 527.7 2.3e-149
NP_001269483 (OMIM: 615566) BTB/POZ domain-contain ( 371) 2468 527.7 2.3e-149
NP_060267 (OMIM: 608531) BTB/POZ domain-containing ( 525) 1303 283.4 1.2e-75
NP_079514 (OMIM: 608530) BTB/POZ domain-containing ( 482) 1244 271.0 5.9e-72
XP_005259650 (OMIM: 608531) PREDICTED: BTB/POZ dom ( 377) 1079 236.3 1.3e-61
NP_001011885 (OMIM: 608530) BTB/POZ domain-contain ( 385) 940 207.1 7.7e-53
XP_011526429 (OMIM: 608531) PREDICTED: BTB/POZ dom ( 204) 478 110.0 6.9e-24
XP_011512584 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 387) 321 77.2 9.6e-14
XP_016865716 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 387) 321 77.2 9.6e-14
XP_011512583 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 391) 321 77.3 9.7e-14
XP_011512582 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 401) 321 77.3 9.9e-14
NP_443125 (OMIM: 611237) BTB/POZ domain-containing ( 612) 321 77.4 1.4e-13
NP_001092742 (OMIM: 611237) BTB/POZ domain-contain ( 612) 321 77.4 1.4e-13
XP_011512581 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 612) 321 77.4 1.4e-13
NP_006054 (OMIM: 607701,615731) kelch-like protein ( 606) 288 70.4 1.7e-11
XP_016867930 (OMIM: 611119,612943,617055) PREDICTE ( 303) 260 64.4 5.6e-10
XP_016867929 (OMIM: 611119,612943,617055) PREDICTE ( 325) 260 64.4 5.9e-10
NP_001165889 (OMIM: 611237) BTB/POZ domain-contain ( 582) 262 65.0 7.2e-10
NP_061334 (OMIM: 611119,612943,617055) kelch-like ( 538) 260 64.5 9e-10
XP_016867928 (OMIM: 611119,612943,617055) PREDICTE ( 564) 260 64.5 9.3e-10
NP_001026880 (OMIM: 611119,612943,617055) kelch-li ( 586) 260 64.6 9.6e-10
NP_001278932 (OMIM: 611967) kelch-like protein 8 i ( 620) 251 62.7 3.7e-09
NP_065854 (OMIM: 611967) kelch-like protein 8 isof ( 620) 251 62.7 3.7e-09
NP_689606 (OMIM: 615340,615348) kelch-like protein ( 621) 247 61.8 6.7e-09
NP_001316524 (OMIM: 608778,615081) kelch-like prot ( 608) 244 61.2 1e-08
NP_689680 (OMIM: 608778,615081) kelch-like protein ( 608) 244 61.2 1e-08
NP_987096 (OMIM: 606016) kelch-like ECH-associated ( 624) 241 60.6 1.6e-08
XP_005260230 (OMIM: 606016) PREDICTED: kelch-like ( 624) 241 60.6 1.6e-08
XP_005260231 (OMIM: 606016) PREDICTED: kelch-like ( 624) 241 60.6 1.6e-08
XP_011526754 (OMIM: 606016) PREDICTED: kelch-like ( 624) 241 60.6 1.6e-08
NP_036421 (OMIM: 606016) kelch-like ECH-associated ( 624) 241 60.6 1.6e-08
NP_689946 (OMIM: 611237) BTB/POZ domain-containing ( 544) 240 60.3 1.7e-08
XP_011529874 (OMIM: 605774) PREDICTED: kelch-like ( 633) 239 60.2 2.2e-08
NP_001007076 (OMIM: 608064) kelch-like protein 5 i ( 709) 235 59.4 4.3e-08
NP_057074 (OMIM: 608064) kelch-like protein 5 isof ( 755) 235 59.4 4.5e-08
XP_011512002 (OMIM: 608064) PREDICTED: kelch-like ( 788) 235 59.4 4.7e-08
XP_011512003 (OMIM: 608064) PREDICTED: kelch-like ( 788) 235 59.4 4.7e-08
XP_016863765 (OMIM: 608064) PREDICTED: kelch-like ( 788) 235 59.4 4.7e-08
XP_016863764 (OMIM: 608064) PREDICTED: kelch-like ( 788) 235 59.4 4.7e-08
XP_005262712 (OMIM: 608064) PREDICTED: kelch-like ( 789) 235 59.4 4.7e-08
XP_016863763 (OMIM: 608064) PREDICTED: kelch-like ( 804) 235 59.4 4.7e-08
XP_011512001 (OMIM: 608064) PREDICTED: kelch-like ( 804) 235 59.4 4.7e-08
XP_016863762 (OMIM: 608064) PREDICTED: kelch-like ( 804) 235 59.4 4.7e-08
>>NP_055777 (OMIM: 615566) BTB/POZ domain-containing pro (522 aa)
initn: 3470 init1: 3470 opt: 3470 Z-score: 3936.4 bits: 738.0 E(85289): 1.6e-212
Smith-Waterman score: 3470; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KSD MVDDKEKNMKCLTFFLMLPETVKNRSKKSSKKANTSSSSSNSSKLPPVCYEIITLKTKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MVDDKEKNMKCLTFFLMLPETVKNRSKKSSKKANTSSSSSNSSKLPPVCYEIITLKTKKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KMAADIFPRKKPANSSSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRERNAMMFNNDLMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KMAADIFPRKKPANSSSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRERNAMMFNNDLMA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DVHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDVEPAAFLAMLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DVHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDVEPAAFLAMLKY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD IYCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IYCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TQRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TQRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD DLALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DLALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QFVSKARKGLVPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QFVSKARKGLVPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EYSAKIELKRQGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EYSAKIELKRQGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSY
430 440 450 460 470 480
490 500 510 520
pF1KSD FGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
::::::::::::::::::::::::::::::::::::::::::
NP_055 FGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
490 500 510 520
>>NP_852108 (OMIM: 615566) BTB/POZ domain-containing pro (565 aa)
initn: 3338 init1: 3338 opt: 3338 Z-score: 3786.2 bits: 710.3 E(85289): 3.7e-204
Smith-Waterman score: 3338; 100.0% identity (100.0% similar) in 503 aa overlap (20-522:63-565)
10 20 30 40
pF1KSD MVDDKEKNMKCLTFFLMLPETVKNRSKKSSKKANTSSSSSNSSKLPPVC
::::::::::::::::::::::::::::::
NP_852 ISECPGRGLRSGHRARRRTAASPEARRSAGETVKNRSKKSSKKANTSSSSSNSSKLPPVC
40 50 60 70 80 90
50 60 70 80 90 100
pF1KSD YEIITLKTKKKKMAADIFPRKKPANSSSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 YEIITLKTKKKKMAADIFPRKKPANSSSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRER
100 110 120 130 140 150
110 120 130 140 150 160
pF1KSD NAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 NAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDV
160 170 180 190 200 210
170 180 190 200 210 220
pF1KSD EPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLL
220 230 240 250 260 270
230 240 250 260 270 280
pF1KSD SQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 SQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAA
280 290 300 310 320 330
290 300 310 320 330 340
pF1KSD LNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 LNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIF
340 350 360 370 380 390
350 360 370 380 390 400
pF1KSD LWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 LWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAG
400 410 420 430 440 450
410 420 430 440 450 460
pF1KSD FGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 FGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTA
460 470 480 490 500 510
470 480 490 500 510 520
pF1KSD SVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 SVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
520 530 540 550 560
>>XP_016883218 (OMIM: 615566) PREDICTED: BTB/POZ domain- (461 aa)
initn: 3086 init1: 3086 opt: 3086 Z-score: 3501.8 bits: 657.4 E(85289): 2.6e-188
Smith-Waterman score: 3086; 100.0% identity (100.0% similar) in 461 aa overlap (62-522:1-461)
40 50 60 70 80 90
pF1KSD KANTSSSSSNSSKLPPVCYEIITLKTKKKKMAADIFPRKKPANSSSTSVQQYHQQNLSNN
::::::::::::::::::::::::::::::
XP_016 MAADIFPRKKPANSSSTSVQQYHQQNLSNN
10 20 30
100 110 120 130 140 150
pF1KSD NLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHA
40 50 60 70 80 90
160 170 180 190 200 210
pF1KSD MFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARA
100 110 120 130 140 150
220 230 240 250 260 270
pF1KSD CVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLES
160 170 180 190 200 210
280 290 300 310 320 330
pF1KSD ILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFA
220 230 240 250 260 270
340 350 360 370 380 390
pF1KSD NGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRYR
280 290 300 310 320 330
400 410 420 430 440 450
pF1KSD GRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNTF
340 350 360 370 380 390
460 470 480 490 500 510
pF1KSD PVWFEYPVQIEPDTFYTASVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVWFEYPVQIEPDTFYTASVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQ
400 410 420 430 440 450
520
pF1KSD GGQIPELIFYA
:::::::::::
XP_016 GGQIPELIFYA
460
>>NP_001269479 (OMIM: 615566) BTB/POZ domain-containing (461 aa)
initn: 3086 init1: 3086 opt: 3086 Z-score: 3501.8 bits: 657.4 E(85289): 2.6e-188
Smith-Waterman score: 3086; 100.0% identity (100.0% similar) in 461 aa overlap (62-522:1-461)
40 50 60 70 80 90
pF1KSD KANTSSSSSNSSKLPPVCYEIITLKTKKKKMAADIFPRKKPANSSSTSVQQYHQQNLSNN
::::::::::::::::::::::::::::::
NP_001 MAADIFPRKKPANSSSTSVQQYHQQNLSNN
10 20 30
100 110 120 130 140 150
pF1KSD NLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHA
40 50 60 70 80 90
160 170 180 190 200 210
pF1KSD MFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARA
100 110 120 130 140 150
220 230 240 250 260 270
pF1KSD CVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLES
160 170 180 190 200 210
280 290 300 310 320 330
pF1KSD ILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFA
220 230 240 250 260 270
340 350 360 370 380 390
pF1KSD NGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRYR
280 290 300 310 320 330
400 410 420 430 440 450
pF1KSD GRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNTF
340 350 360 370 380 390
460 470 480 490 500 510
pF1KSD PVWFEYPVQIEPDTFYTASVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVWFEYPVQIEPDTFYTASVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQ
400 410 420 430 440 450
520
pF1KSD GGQIPELIFYA
:::::::::::
NP_001 GGQIPELIFYA
460
>>NP_001269480 (OMIM: 615566) BTB/POZ domain-containing (461 aa)
initn: 3086 init1: 3086 opt: 3086 Z-score: 3501.8 bits: 657.4 E(85289): 2.6e-188
Smith-Waterman score: 3086; 100.0% identity (100.0% similar) in 461 aa overlap (62-522:1-461)
40 50 60 70 80 90
pF1KSD KANTSSSSSNSSKLPPVCYEIITLKTKKKKMAADIFPRKKPANSSSTSVQQYHQQNLSNN
::::::::::::::::::::::::::::::
NP_001 MAADIFPRKKPANSSSTSVQQYHQQNLSNN
10 20 30
100 110 120 130 140 150
pF1KSD NLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHA
40 50 60 70 80 90
160 170 180 190 200 210
pF1KSD MFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARA
100 110 120 130 140 150
220 230 240 250 260 270
pF1KSD CVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLES
160 170 180 190 200 210
280 290 300 310 320 330
pF1KSD ILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFA
220 230 240 250 260 270
340 350 360 370 380 390
pF1KSD NGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRYR
280 290 300 310 320 330
400 410 420 430 440 450
pF1KSD GRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNTF
340 350 360 370 380 390
460 470 480 490 500 510
pF1KSD PVWFEYPVQIEPDTFYTASVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVWFEYPVQIEPDTFYTASVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQ
400 410 420 430 440 450
520
pF1KSD GGQIPELIFYA
:::::::::::
NP_001 GGQIPELIFYA
460
>>XP_016883217 (OMIM: 615566) PREDICTED: BTB/POZ domain- (461 aa)
initn: 3086 init1: 3086 opt: 3086 Z-score: 3501.8 bits: 657.4 E(85289): 2.6e-188
Smith-Waterman score: 3086; 100.0% identity (100.0% similar) in 461 aa overlap (62-522:1-461)
40 50 60 70 80 90
pF1KSD KANTSSSSSNSSKLPPVCYEIITLKTKKKKMAADIFPRKKPANSSSTSVQQYHQQNLSNN
::::::::::::::::::::::::::::::
XP_016 MAADIFPRKKPANSSSTSVQQYHQQNLSNN
10 20 30
100 110 120 130 140 150
pF1KSD NLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHA
40 50 60 70 80 90
160 170 180 190 200 210
pF1KSD MFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARA
100 110 120 130 140 150
220 230 240 250 260 270
pF1KSD CVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLES
160 170 180 190 200 210
280 290 300 310 320 330
pF1KSD ILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFA
220 230 240 250 260 270
340 350 360 370 380 390
pF1KSD NGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRYR
280 290 300 310 320 330
400 410 420 430 440 450
pF1KSD GRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNTF
340 350 360 370 380 390
460 470 480 490 500 510
pF1KSD PVWFEYPVQIEPDTFYTASVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVWFEYPVQIEPDTFYTASVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGVQ
400 410 420 430 440 450
520
pF1KSD GGQIPELIFYA
:::::::::::
XP_016 GGQIPELIFYA
460
>>NP_001269481 (OMIM: 615566) BTB/POZ domain-containing (371 aa)
initn: 2468 init1: 2468 opt: 2468 Z-score: 2802.4 bits: 527.7 E(85289): 2.3e-149
Smith-Waterman score: 2468; 100.0% identity (100.0% similar) in 371 aa overlap (152-522:1-371)
130 140 150 160 170 180
pF1KSD VHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDVEPAAFLAMLKYI
::::::::::::::::::::::::::::::
NP_001 MFYGELAEDKDEIRIPDVEPAAFLAMLKYI
10 20 30
190 200 210 220 230 240
pF1KSD YCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLT
40 50 60 70 80 90
250 260 270 280 290 300
pF1KSD QRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQD
100 110 120 130 140 150
310 320 330 340 350 360
pF1KSD LALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQ
160 170 180 190 200 210
370 380 390 400 410 420
pF1KSD FVSKARKGLVPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVSKARKGLVPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAE
220 230 240 250 260 270
430 440 450 460 470 480
pF1KSD YSAKIELKRQGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSAKIELKRQGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
280 290 300 310 320 330
490 500 510 520
pF1KSD GQEGMTEVQCGKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
:::::::::::::::::::::::::::::::::::::::::
NP_001 GQEGMTEVQCGKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
340 350 360 370
>>XP_016883219 (OMIM: 615566) PREDICTED: BTB/POZ domain- (371 aa)
initn: 2468 init1: 2468 opt: 2468 Z-score: 2802.4 bits: 527.7 E(85289): 2.3e-149
Smith-Waterman score: 2468; 100.0% identity (100.0% similar) in 371 aa overlap (152-522:1-371)
130 140 150 160 170 180
pF1KSD VHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDVEPAAFLAMLKYI
::::::::::::::::::::::::::::::
XP_016 MFYGELAEDKDEIRIPDVEPAAFLAMLKYI
10 20 30
190 200 210 220 230 240
pF1KSD YCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLT
40 50 60 70 80 90
250 260 270 280 290 300
pF1KSD QRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQD
100 110 120 130 140 150
310 320 330 340 350 360
pF1KSD LALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQ
160 170 180 190 200 210
370 380 390 400 410 420
pF1KSD FVSKARKGLVPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVSKARKGLVPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAE
220 230 240 250 260 270
430 440 450 460 470 480
pF1KSD YSAKIELKRQGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSAKIELKRQGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
280 290 300 310 320 330
490 500 510 520
pF1KSD GQEGMTEVQCGKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
:::::::::::::::::::::::::::::::::::::::::
XP_016 GQEGMTEVQCGKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
340 350 360 370
>>NP_001269483 (OMIM: 615566) BTB/POZ domain-containing (371 aa)
initn: 2468 init1: 2468 opt: 2468 Z-score: 2802.4 bits: 527.7 E(85289): 2.3e-149
Smith-Waterman score: 2468; 100.0% identity (100.0% similar) in 371 aa overlap (152-522:1-371)
130 140 150 160 170 180
pF1KSD VHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDVEPAAFLAMLKYI
::::::::::::::::::::::::::::::
NP_001 MFYGELAEDKDEIRIPDVEPAAFLAMLKYI
10 20 30
190 200 210 220 230 240
pF1KSD YCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLT
40 50 60 70 80 90
250 260 270 280 290 300
pF1KSD QRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQD
100 110 120 130 140 150
310 320 330 340 350 360
pF1KSD LALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQ
160 170 180 190 200 210
370 380 390 400 410 420
pF1KSD FVSKARKGLVPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVSKARKGLVPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAE
220 230 240 250 260 270
430 440 450 460 470 480
pF1KSD YSAKIELKRQGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSAKIELKRQGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
280 290 300 310 320 330
490 500 510 520
pF1KSD GQEGMTEVQCGKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
:::::::::::::::::::::::::::::::::::::::::
NP_001 GQEGMTEVQCGKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
340 350 360 370
>>NP_060267 (OMIM: 608531) BTB/POZ domain-containing pro (525 aa)
initn: 1266 init1: 957 opt: 1303 Z-score: 1479.2 bits: 283.4 E(85289): 1.2e-75
Smith-Waterman score: 1303; 46.8% identity (75.9% similar) in 436 aa overlap (96-521:93-524)
70 80 90 100 110 120
pF1KSD IFPRKKPANSSSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFV
: :::. ::..:: :..:::... ::::.
NP_060 PGPGTDAQAAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD VGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDE
:: ..::.:.:..::::::.:: ::: : .: . ::..::::::::::.::..: ::
NP_060 VGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD IDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCW
.... .::..:::.:::: :: : ::.::. .: : :: .::.:. ::.::.:.. :
NP_060 VQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQDLALS
: :: .. :. .::: :::..:: ..:.:.::. .:. .:.:.. :.:.:::::.: ..
NP_060 ENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD IENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSK
::.:::::::: :::.: :....:: : ::::.:. :. ..:: .:. ::...:...
NP_060 PENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD ARKGLVPQRC--HRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYS
: : ..: .:::. : : : : : :.:.:.::.:..::::::: : ..:.
NP_060 PRCCLRGKECSINRFQQVESR---WGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQ
370 380 390 400 410
430 440 450 460 470 480
pF1KSD AKIELKR--QGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
..:.. . ...::::: . . :::..:: : :. ::.. :.. ::: . : : . :..
NP_060 VNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPD-SHY
420 430 440 450 460 470
490 500 510 520
pF1KSD GQEGMTEVQ-----CG-KVTVQFQCSSDSTNGTGVQGGQIPELIFYA
: .:. .: : :. : .. ..:::.:. :::::.:::
NP_060 GTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
480 490 500 510 520
522 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 04:22:12 2016 done: Thu Nov 3 04:22:14 2016
Total Scan time: 9.480 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]