Result of FASTA (omim) for
pF1KSDA0939
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0939, 581 aa
1>>>pF1KSDA0939 581 - 581 aa - 581 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5765+/-0.000509; mu= 17.1280+/- 0.031
mean_var=70.1812+/-14.539, 0's: 0 Z-trim(107.2): 74 B-trim: 0 in 0/52
Lambda= 0.153096
statistics sampled from 15221 (15286) to 15221 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.519), E-opt: 0.2 (0.179), width: 16
Scan time: 9.550
The best scores are: opt bits E(85289)
NP_056081 (OMIM: 612730) sodium/hydrogen exchanger ( 581) 3764 841.4 0
XP_011527041 (OMIM: 612730) PREDICTED: sodium/hydr ( 589) 3414 764.1 0
NP_001247420 (OMIM: 612730) sodium/hydrogen exchan ( 597) 2630 591.0 3.8e-168
XP_006723819 (OMIM: 612730) PREDICTED: sodium/hydr ( 614) 2256 508.4 2.8e-143
XP_011527039 (OMIM: 612730) PREDICTED: sodium/hydr ( 602) 2250 507.0 7e-143
XP_011527038 (OMIM: 612730) PREDICTED: sodium/hydr ( 630) 2250 507.0 7.3e-143
XP_016883244 (OMIM: 612730) PREDICTED: sodium/hydr ( 395) 2242 505.2 1.7e-142
XP_011527044 (OMIM: 612730) PREDICTED: sodium/hydr ( 395) 2242 505.2 1.7e-142
XP_016883245 (OMIM: 612730) PREDICTED: sodium/hydr ( 334) 2198 495.4 1.2e-139
XP_011527045 (OMIM: 612730) PREDICTED: sodium/hydr ( 334) 2198 495.4 1.2e-139
XP_011527046 (OMIM: 612730) PREDICTED: sodium/hydr ( 304) 1962 443.3 5.5e-124
XP_011527040 (OMIM: 612730) PREDICTED: sodium/hydr ( 591) 1854 419.6 1.5e-116
XP_016883243 (OMIM: 612730) PREDICTED: sodium/hydr ( 565) 1689 383.1 1.3e-105
XP_011527042 (OMIM: 612730) PREDICTED: sodium/hydr ( 564) 1682 381.6 3.9e-105
XP_011527043 (OMIM: 612730) PREDICTED: sodium/hydr ( 558) 1507 342.9 1.7e-93
XP_011527047 (OMIM: 612730) PREDICTED: sodium/hydr ( 299) 1165 267.2 5.3e-71
XP_016861691 (OMIM: 608396,613410) PREDICTED: sodi ( 578) 931 215.7 3.4e-55
NP_775924 (OMIM: 608396,613410) sodium/hydrogen ex ( 645) 931 215.7 3.7e-55
XP_016861692 (OMIM: 608396,613410) PREDICTED: sodi ( 528) 927 214.8 5.8e-55
XP_016885395 (OMIM: 300368) PREDICTED: sodium/hydr ( 706) 914 212.0 5.4e-54
XP_006724627 (OMIM: 300368) PREDICTED: sodium/hydr ( 706) 914 212.0 5.4e-54
XP_011542292 (OMIM: 300368) PREDICTED: sodium/hydr ( 726) 913 211.8 6.5e-54
XP_005272739 (OMIM: 300368) PREDICTED: sodium/hydr ( 726) 913 211.8 6.5e-54
XP_016885394 (OMIM: 300368) PREDICTED: sodium/hydr ( 726) 913 211.8 6.5e-54
XP_005272738 (OMIM: 300368) PREDICTED: sodium/hydr ( 726) 913 211.8 6.5e-54
NP_001244220 (OMIM: 300368) sodium/hydrogen exchan ( 726) 913 211.8 6.5e-54
NP_115980 (OMIM: 300368) sodium/hydrogen exchanger ( 725) 890 206.7 2.2e-52
NP_001317581 (OMIM: 300231,300243) sodium/hydrogen ( 617) 889 206.4 2.2e-52
XP_016884714 (OMIM: 300231,300243) PREDICTED: sodi ( 617) 889 206.4 2.2e-52
NP_006350 (OMIM: 300231,300243) sodium/hydrogen ex ( 669) 889 206.4 2.4e-52
NP_001171122 (OMIM: 300231,300243) sodium/hydrogen ( 649) 881 204.7 7.9e-52
XP_016884712 (OMIM: 300231,300243) PREDICTED: sodi ( 649) 881 204.7 7.9e-52
XP_006724789 (OMIM: 300231,300243) PREDICTED: sodi ( 649) 881 204.7 7.9e-52
XP_016884713 (OMIM: 300231,300243) PREDICTED: sodi ( 649) 881 204.7 7.9e-52
NP_001036002 (OMIM: 300231,300243) sodium/hydrogen ( 701) 881 204.7 8.4e-52
XP_016879083 (OMIM: 600477) PREDICTED: sodium/hydr ( 544) 780 182.3 3.5e-45
NP_003038 (OMIM: 107310,616291) sodium/hydrogen ex ( 815) 782 182.8 3.7e-45
NP_001310900 (OMIM: 600477) sodium/hydrogen exchan ( 675) 780 182.4 4.2e-45
NP_001310902 (OMIM: 600477) sodium/hydrogen exchan ( 895) 780 182.4 5.4e-45
NP_004585 (OMIM: 600477) sodium/hydrogen exchanger ( 896) 780 182.4 5.4e-45
XP_011540323 (OMIM: 107310,616291) PREDICTED: sodi ( 705) 769 179.9 2.4e-44
NP_001011552 (OMIM: 600531) sodium/hydrogen exchan ( 798) 758 177.5 1.4e-43
NP_004165 (OMIM: 182307,616868) sodium/hydrogen ex ( 834) 757 177.3 1.7e-43
NP_003039 (OMIM: 600530) sodium/hydrogen exchanger ( 812) 754 176.7 2.7e-43
NP_001271280 (OMIM: 182307,616868) sodium/hydrogen ( 825) 724 170.0 2.7e-41
XP_011511005 (OMIM: 608396,613410) PREDICTED: sodi ( 429) 668 157.5 8e-38
XP_011509460 (OMIM: 600531) PREDICTED: sodium/hydr ( 769) 594 141.3 1.1e-32
NP_001310901 (OMIM: 600477) sodium/hydrogen exchan ( 795) 533 127.8 1.3e-28
XP_011511006 (OMIM: 608396,613410) PREDICTED: sodi ( 369) 520 124.8 4.9e-28
NP_001310903 (OMIM: 600477) sodium/hydrogen exchan ( 600) 291 74.3 1.2e-12
>>NP_056081 (OMIM: 612730) sodium/hydrogen exchanger 8 i (581 aa)
initn: 3764 init1: 3764 opt: 3764 Z-score: 4493.6 bits: 841.4 E(85289): 0
Smith-Waterman score: 3764; 100.0% identity (100.0% similar) in 581 aa overlap (1-581:1-581)
10 20 30 40 50 60
pF1KSD MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD MMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD WFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 WFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAHYIRRQDLKGFVWLDAKYLNPFFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAHYIRRQDLKGFVWLDAKYLNPFFT
490 500 510 520 530 540
550 560 570 580
pF1KSD RRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDEQELL
:::::::::::::::::::::::::::::::::::::::::
NP_056 RRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDEQELL
550 560 570 580
>>XP_011527041 (OMIM: 612730) PREDICTED: sodium/hydrogen (589 aa)
initn: 3096 init1: 1962 opt: 3414 Z-score: 4075.7 bits: 764.1 E(85289): 0
Smith-Waterman score: 3414; 90.8% identity (92.5% similar) in 597 aa overlap (1-581:1-589)
10 20 30 40 50 60
pF1KSD MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
70 80 90 100 110 120
130 140 150 160 170
pF1KSD FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQ--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQGF
130 140 150 160 170 180
180 190 200 210 220
pF1KSD --------------ADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFG
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFVCVCVFVCFILQADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD ESILNDAVSIVLTNTAEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISAL
::::::::::::::: : . . .: .. . : ...: . : :
XP_011 ESILNDAVSIVLTNTEEKYAPGSCCHLS---LVIRIIPGFEEVYFINDHLQ-----IVIY
250 260 270 280 290
290 300 310 320 330 340
pF1KSD VLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQ
300 310 320 330 340 350
350 360 370 380 390 400
pF1KSD ILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLL
360 370 380 390 400 410
410 420 430 440 450 460
pF1KSD NFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLG
420 430 440 450 460 470
470 480 490 500 510 520
pF1KSD GSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAHYIRRQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAHYIRRQDL
480 490 500 510 520 530
530 540 550 560 570 580
pF1KSD KGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDEQELL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDEQELL
540 550 560 570 580
>>NP_001247420 (OMIM: 612730) sodium/hydrogen exchanger (597 aa)
initn: 2630 init1: 2630 opt: 2630 Z-score: 3139.8 bits: 591.0 E(85289): 3.8e-168
Smith-Waterman score: 3722; 97.3% identity (97.3% similar) in 597 aa overlap (1-581:1-597)
10 20 30 40 50 60
pF1KSD MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
70 80 90 100 110 120
130 140 150 160 170
pF1KSD FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQ--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQGF
130 140 150 160 170 180
180 190 200 210 220
pF1KSD --------------ADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFG
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFVCVCVFVCFILQADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD ESILNDAVSIVLTNTAEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESILNDAVSIVLTNTAEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISAL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KSD VLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQ
310 320 330 340 350 360
350 360 370 380 390 400
pF1KSD ILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KSD NFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLG
430 440 450 460 470 480
470 480 490 500 510 520
pF1KSD GSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAHYIRRQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAHYIRRQDL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KSD KGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDEQELL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDEQELL
550 560 570 580 590
>>XP_006723819 (OMIM: 612730) PREDICTED: sodium/hydrogen (614 aa)
initn: 2242 init1: 2242 opt: 2256 Z-score: 2693.2 bits: 508.4 E(85289): 2.8e-143
Smith-Waterman score: 3676; 94.5% identity (94.6% similar) in 613 aa overlap (2-581:2-614)
10 20 30 40 50 60
pF1KSD MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQAD
130 140 150 160 170 180
190 200 210 220 230
pF1KSD VISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNT-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTE
190 200 210 220 230 240
240 250 260
pF1KSD --------------------------------AEGLTRKNMSDVSGWQTFLQALDYFLKM
.:::::::::::::::::::::::::::
XP_006 EKYAPGSCCHLSLVIRIIPGFEEVYFINDHLQTEGLTRKNMSDVSGWQTFLQALDYFLKM
250 260 270 280 290 300
270 280 290 300 310 320
pF1KSD FFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFS
310 320 330 340 350 360
330 340 350 360 370 380
pF1KSD GIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIV
370 380 390 400 410 420
390 400 410 420 430 440
pF1KSD LVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQL
430 440 450 460 470 480
450 460 470 480 490 500
pF1KSD IGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLS
490 500 510 520 530 540
510 520 530 540 550 560
pF1KSD ELTEEEYEAHYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELTEEEYEAHYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVR
550 560 570 580 590 600
570 580
pF1KSD QGPSGSEDDEQELL
::::::::::::::
XP_006 QGPSGSEDDEQELL
610
>>XP_011527039 (OMIM: 612730) PREDICTED: sodium/hydrogen (602 aa)
initn: 2965 init1: 2242 opt: 2250 Z-score: 2686.1 bits: 507.0 E(85289): 7e-143
Smith-Waterman score: 3384; 87.6% identity (87.8% similar) in 630 aa overlap (1-581:1-602)
10 20 30 40 50 60
pF1KSD MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWK----
70 80 90 100 110
130 140 150 160 170
pF1KSD FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQ--
::::::::::::::::::::::::::::::::::
XP_011 ------------------------GNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQGF
120 130 140 150
180 190 200 210 220
pF1KSD --------------ADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFG
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFVCVCVFVCFILQADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFG
160 170 180 190 200 210
230 240 250
pF1KSD ESILNDAVSIVLTNT---------------------------------AEGLTRKNMSDV
::::::::::::::: .:::::::::::
XP_011 ESILNDAVSIVLTNTEEKYAPGSCCHLSLVIRIIPGFEEVYFINDHLQTEGLTRKNMSDV
220 230 240 250 260 270
260 270 280 290 300 310
pF1KSD SGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYG
280 290 300 310 320 330
320 330 340 350 360 370
pF1KSD LAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIF
340 350 360 370 380 390
380 390 400 410 420 430
pF1KSD SFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPY
400 410 420 430 440 450
440 450 460 470 480 490
pF1KSD ALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNL
460 470 480 490 500 510
500 510 520 530 540 550
pF1KSD SKTEKMGNTVESEHLSELTEEEYEAHYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKTEKMGNTVESEHLSELTEEEYEAHYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHG
520 530 540 550 560 570
560 570 580
pF1KSD RIQMKTLTNKWYEEVRQGPSGSEDDEQELL
::::::::::::::::::::::::::::::
XP_011 RIQMKTLTNKWYEEVRQGPSGSEDDEQELL
580 590 600
>>XP_011527038 (OMIM: 612730) PREDICTED: sodium/hydrogen (630 aa)
initn: 3376 init1: 2242 opt: 2250 Z-score: 2685.8 bits: 507.0 E(85289): 7.3e-143
Smith-Waterman score: 3526; 91.8% identity (92.0% similar) in 613 aa overlap (18-581:18-630)
10 20 30 40 50 60
pF1KSD MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
:::::::::::::::::::::::::::::::::::::::::::
XP_011 MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
70 80 90 100 110 120
130 140 150 160 170
pF1KSD FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQ--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQGF
130 140 150 160 170 180
180 190 200 210 220
pF1KSD --------------ADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFG
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFVCVCVFVCFILQADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFG
190 200 210 220 230 240
230 240 250
pF1KSD ESILNDAVSIVLTNT---------------------------------AEGLTRKNMSDV
::::::::::::::: .:::::::::::
XP_011 ESILNDAVSIVLTNTEEKYAPGSCCHLSLVIRIIPGFEEVYFINDHLQTEGLTRKNMSDV
250 260 270 280 290 300
260 270 280 290 300 310
pF1KSD SGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYG
310 320 330 340 350 360
320 330 340 350 360 370
pF1KSD LAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIF
370 380 390 400 410 420
380 390 400 410 420 430
pF1KSD SFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPY
430 440 450 460 470 480
440 450 460 470 480 490
pF1KSD ALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNL
490 500 510 520 530 540
500 510 520 530 540 550
pF1KSD SKTEKMGNTVESEHLSELTEEEYEAHYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKTEKMGNTVESEHLSELTEEEYEAHYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHG
550 560 570 580 590 600
560 570 580
pF1KSD RIQMKTLTNKWYEEVRQGPSGSEDDEQELL
::::::::::::::::::::::::::::::
XP_011 RIQMKTLTNKWYEEVRQGPSGSEDDEQELL
610 620 630
>>XP_016883244 (OMIM: 612730) PREDICTED: sodium/hydrogen (395 aa)
initn: 2242 init1: 2242 opt: 2242 Z-score: 2679.4 bits: 505.2 E(85289): 1.7e-142
Smith-Waterman score: 2282; 91.4% identity (91.6% similar) in 395 aa overlap (220-581:1-395)
190 200 210 220 230
pF1KSD SFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNT----------
::::::::::::::::::::
XP_016 MLVFGESILNDAVSIVLTNTEEKYAPGSCC
10 20 30
240 250 260 270
pF1KSD -----------------------AEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGT
.::::::::::::::::::::::::::::::::::::
XP_016 HLSLVIRIIPGFEEVYFINDHLQTEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGT
40 50 60 70 80 90
280 290 300 310 320 330
pF1KSD LTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTH
100 110 120 130 140 150
340 350 360 370 380 390
pF1KSD HNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVN
160 170 180 190 200 210
400 410 420 430 440 450
pF1KSD IFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIV
220 230 240 250 260 270
460 470 480 490 500 510
pF1KSD LFTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEA
280 290 300 310 320 330
520 530 540 550 560 570
pF1KSD HYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDD
340 350 360 370 380 390
580
pF1KSD EQELL
:::::
XP_016 EQELL
>>XP_011527044 (OMIM: 612730) PREDICTED: sodium/hydrogen (395 aa)
initn: 2242 init1: 2242 opt: 2242 Z-score: 2679.4 bits: 505.2 E(85289): 1.7e-142
Smith-Waterman score: 2282; 91.4% identity (91.6% similar) in 395 aa overlap (220-581:1-395)
190 200 210 220 230
pF1KSD SFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNT----------
::::::::::::::::::::
XP_011 MLVFGESILNDAVSIVLTNTEEKYAPGSCC
10 20 30
240 250 260 270
pF1KSD -----------------------AEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGT
.::::::::::::::::::::::::::::::::::::
XP_011 HLSLVIRIIPGFEEVYFINDHLQTEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGT
40 50 60 70 80 90
280 290 300 310 320 330
pF1KSD LTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTH
100 110 120 130 140 150
340 350 360 370 380 390
pF1KSD HNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVN
160 170 180 190 200 210
400 410 420 430 440 450
pF1KSD IFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIV
220 230 240 250 260 270
460 470 480 490 500 510
pF1KSD LFTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEA
280 290 300 310 320 330
520 530 540 550 560 570
pF1KSD HYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDD
340 350 360 370 380 390
580
pF1KSD EQELL
:::::
XP_011 EQELL
>>XP_016883245 (OMIM: 612730) PREDICTED: sodium/hydrogen (334 aa)
initn: 2198 init1: 2198 opt: 2198 Z-score: 2628.0 bits: 495.4 E(85289): 1.2e-139
Smith-Waterman score: 2198; 100.0% identity (100.0% similar) in 334 aa overlap (248-581:1-334)
220 230 240 250 260 270
pF1KSD LNMLVFGESILNDAVSIVLTNTAEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTL
::::::::::::::::::::::::::::::
XP_016 MSDVSGWQTFLQALDYFLKMFFGSAALGTL
10 20 30
280 290 300 310 320 330
pF1KSD TGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHH
40 50 60 70 80 90
340 350 360 370 380 390
pF1KSD NLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNI
100 110 120 130 140 150
400 410 420 430 440 450
pF1KSD FPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVL
160 170 180 190 200 210
460 470 480 490 500 510
pF1KSD FTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAH
220 230 240 250 260 270
520 530 540 550 560 570
pF1KSD YIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDE
280 290 300 310 320 330
580
pF1KSD QELL
::::
XP_016 QELL
>>XP_011527045 (OMIM: 612730) PREDICTED: sodium/hydrogen (334 aa)
initn: 2198 init1: 2198 opt: 2198 Z-score: 2628.0 bits: 495.4 E(85289): 1.2e-139
Smith-Waterman score: 2198; 100.0% identity (100.0% similar) in 334 aa overlap (248-581:1-334)
220 230 240 250 260 270
pF1KSD LNMLVFGESILNDAVSIVLTNTAEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTL
::::::::::::::::::::::::::::::
XP_011 MSDVSGWQTFLQALDYFLKMFFGSAALGTL
10 20 30
280 290 300 310 320 330
pF1KSD TGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHH
40 50 60 70 80 90
340 350 360 370 380 390
pF1KSD NLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNI
100 110 120 130 140 150
400 410 420 430 440 450
pF1KSD FPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVL
160 170 180 190 200 210
460 470 480 490 500 510
pF1KSD FTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTILLLGGSTMPLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAH
220 230 240 250 260 270
520 530 540 550 560 570
pF1KSD YIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDE
280 290 300 310 320 330
580
pF1KSD QELL
::::
XP_011 QELL
581 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 04:19:05 2016 done: Thu Nov 3 04:19:06 2016
Total Scan time: 9.550 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]