Result of FASTA (omim) for
pF1KSDA0547
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0547, 686 aa
1>>>pF1KSDA0547 686 - 686 aa - 686 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2436+/-0.000393; mu= 19.7453+/- 0.024
mean_var=66.3879+/-13.498, 0's: 0 Z-trim(112.0): 54 B-trim: 0 in 0/54
Lambda= 0.157409
statistics sampled from 20708 (20739) to 20708 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.243), width: 16
Scan time: 8.850
The best scores are: opt bits E(85289)
NP_055608 (OMIM: 611246) tRNA wybutosine-synthesiz ( 686) 4662 1068.2 0
NP_057393 (OMIM: 610286) leucine carboxyl methyltr ( 334) 613 148.5 3.9e-35
XP_011544166 (OMIM: 610286) PREDICTED: leucine car ( 357) 593 144.0 9.6e-34
XP_005255411 (OMIM: 610286) PREDICTED: leucine car ( 234) 463 114.3 5.2e-25
NP_001027563 (OMIM: 610286) leucine carboxyl methy ( 279) 350 88.7 3.2e-17
XP_011544164 (OMIM: 610286) PREDICTED: leucine car ( 302) 350 88.7 3.4e-17
>>NP_055608 (OMIM: 611246) tRNA wybutosine-synthesizing (686 aa)
initn: 4662 init1: 4662 opt: 4662 Z-score: 5716.5 bits: 1068.2 E(85289): 0
Smith-Waterman score: 4662; 99.9% identity (100.0% similar) in 686 aa overlap (1-686:1-686)
10 20 30 40 50 60
pF1KSD MGPRSRERRAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGPRSRERRAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYVRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWEVDFPDVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWEVDFPDVAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RKAERIGETPELCALTGPFERGEPASALCFESADYCILGLDLRQLQRVEEALGAAGLDAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RKAERIGETPELCALTGPFERGEPASALCFESADYCILGLDLRQLQRVEEALGAAGLDAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PLHGLERFPDVEAQRRRFLQAGWTACGAVDINEFYHCFLPAEERRRVENIEPFDEFEEWH
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_055 PLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPASVVSSEGQVPNLKRYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPASVVSSEGQVPNLKRYGH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD ASVFLSPDVILSAGGFGEQEGRHCRVSQFHLLSRDCDSEWKGSQIGSCGTGVQWDGRLYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ASVFLSPDVILSAGGFGEQEGRHCRVSQFHLLSRDCDSEWKGSQIGSCGTGVQWDGRLYH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TMTRLSESRVLVLGGRLSPVSPALGVLQLHFFKSEDNNTEDLKVTITKAGRKDDSTLCCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TMTRLSESRVLVLGGRLSPVSPALGVLQLHFFKSEDNNTEDLKVTITKAGRKDDSTLCCW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD RHSTTEVSCQNQEYLFVYGGRSVVEPVLSDWHFLHVGTMAWVRIPVEGEVPEARHSHSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RHSTTEVSCQNQEYLFVYGGRSVVEPVLSDWHFLHVGTMAWVRIPVEGEVPEARHSHSAC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD TWQGGALIAGGLGASEEPLNSVLFLRPISCGFLWESVDIQPPITPRYSHTAHVLNGKLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TWQGGALIAGGLGASEEPLNSVLFLRPISCGFLWESVDIQPPITPRYSHTAHVLNGKLLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD VGGIWIHSSSFPGVTVINLTTGLSSEYQIDTTYVPWPLMLHNHTSILLPEEQQLLLLGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VGGIWIHSSSFPGVTVINLTTGLSSEYQIDTTYVPWPLMLHNHTSILLPEEQQLLLLGGG
610 620 630 640 650 660
670 680
pF1KSD GNCFSFGTYFNPHTVTLDLSSLSAGQ
::::::::::::::::::::::::::
NP_055 GNCFSFGTYFNPHTVTLDLSSLSAGQ
670 680
>>NP_057393 (OMIM: 610286) leucine carboxyl methyltransf (334 aa)
initn: 524 init1: 334 opt: 613 Z-score: 751.7 bits: 148.5 E(85289): 3.9e-35
Smith-Waterman score: 613; 36.1% identity (65.9% similar) in 305 aa overlap (13-314:26-323)
10 20 30 40
pF1KSD MGPRSRERRAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVP-GAA
:..: ....: :: .. :: .::. .: .
NP_057 MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD RRAPLIHRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLA
:.:: :.:::..:...: . ..:::. .. . ::..::::.:. ..::: :
NP_057 RKAPEINRGYFARVHGVSQLIKAFLR-----KTECHCQIVNLGAGMDTTFWRLKDEDLLP
70 80 90 100 110
110 120 130 140 150 160
pF1KSD RAAVWEVDFPDVARRKAERIGETPELCA--LTGPFERGEPASALCFESADYCILGLDLRQ
. .::::: .. :: . : : : . : : .. ..: : ..: :::.
NP_057 -SKYFEVDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRD
120 130 140 150 160 170
170 180 190 200 210 220
pF1KSD LQRVEEALGAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQ
:...:: : .... ::::.:: ::.:. ::..: :. :::. : :.:. :::.
NP_057 LSELEEKLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KSD DAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDINEFYHCFLPAEER
: :::.:....:. . : :.: ..:.:..:.:. :: . .:::. :.:. :: :
NP_057 DRFGQIMIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYN-RLPRAEV
240 250 260 270 280 290
290 300 310 320 330 340
pF1KSD RRVENIEPFDEFEEWHLKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPAS
:.:..: .::.: . :: . :..:
NP_057 SRIESLEFLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
300 310 320 330
>>XP_011544166 (OMIM: 610286) PREDICTED: leucine carboxy (357 aa)
initn: 497 init1: 334 opt: 593 Z-score: 726.8 bits: 144.0 E(85289): 9.6e-34
Smith-Waterman score: 593; 36.1% identity (65.3% similar) in 294 aa overlap (24-314:60-346)
10 20 30 40 50
pF1KSD MGPRSRERRAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVP-GAARRAPLI
.: .. :: .::. .: . :.:: :
XP_011 ILATLIGWTVRSFFLGRMETCCSHLGLRSGRRFAVSIGYWHDPYIQHFVRLSKERKAPEI
30 40 50 60 70 80
60 70 80 90 100 110
pF1KSD HRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWE
.:::..:...: . ..:::. .. . ::..::::.:. ..::: : . .:
XP_011 NRGYFARVHGVSQLIKAFLR-----KTECHCQIVNLGAGMDTTFWRLKDEDLLP-SKYFE
90 100 110 120 130 140
120 130 140 150 160 170
pF1KSD VDFPDVARRKAERIGETPELCA--LTGPFERGEPASALCFESADYCILGLDLRQLQRVEE
:::: .. :: . : : : . : : .. ..: : ..: :::.:...::
XP_011 VDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEE
150 160 170 180 190 200
180 190 200 210 220 230
pF1KSD ALGAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQF
: .... ::::.:: ::.:. ::..: :. :::. : :.:. :::. : :::.
XP_011 KLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI
210 220 230 240 250 260
240 250 260 270 280 290
pF1KSD MLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDINEFYHCFLPAEERRRVENI
:....:. . : :.: ..:.:..:.:. :: . .:::. :.:. :: : :.:..
XP_011 MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYN-RLPRAEVSRIESL
270 280 290 300 310 320
300 310 320 330 340 350
pF1KSD EPFDEFEEWHLKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPASVVSSEG
: .::.: . :: . :..:
XP_011 EFLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
330 340 350
>>XP_005255411 (OMIM: 610286) PREDICTED: leucine carboxy (234 aa)
initn: 371 init1: 334 opt: 463 Z-score: 569.9 bits: 114.3 E(85289): 5.2e-25
Smith-Waterman score: 463; 36.6% identity (64.3% similar) in 224 aa overlap (93-314:2-223)
70 80 90 100 110 120
pF1KSD VRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWEVDFPDVARRK
:. ..::: : . .::::: .. ::
XP_005 MDTTFWRLKDEDLLP-SKYFEVDFPMIVTRK
10 20 30
130 140 150 160 170 180
pF1KSD AERIGETPELCA--LTGPFERGEPASALCFESADYCILGLDLRQLQRVEEALGAAGLDAA
. : : : . : : .. ..: : ..: :::.:...:: : ....
XP_005 LHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEEKLKKCNMNTQ
40 50 60 70 80 90
190 200 210 220 230 240
pF1KSD SPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNS
::::.:: ::.:. ::..: :. :::. : :.:. :::. : :::.:....:. .
XP_005 LPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQC
100 110 120 130 140 150
250 260 270 280 290 300
pF1KSD PLHGLERFPDVEAQRRRFLQAGWTACGAVDINEFYHCFLPAEERRRVENIEPFDEFEEWH
: :.: ..:.:..:.:. :: . .:::. :.:. :: : :.:..: .::.: .
XP_005 DLAGVETCKSLESQKERLLSNGWETASAVDMMELYN-RLPRAEVSRIESLEFLDEMELLE
160 170 180 190 200
310 320 330 340 350 360
pF1KSD LKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPASVVSSEGQVPNLKRYGH
:: . :..:
XP_005 QLMRHYCLCWATKGGNELGLKEITY
210 220 230
>>NP_001027563 (OMIM: 610286) leucine carboxyl methyltra (279 aa)
initn: 486 init1: 295 opt: 350 Z-score: 430.1 bits: 88.7 E(85289): 3.2e-17
Smith-Waterman score: 450; 32.0% identity (57.4% similar) in 303 aa overlap (13-314:26-268)
10 20 30 40
pF1KSD MGPRSRERRAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVP-GAA
:..: ....: :: .. :: .::. .: .
NP_001 MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD RRAPLIHRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLA
:.:: :.:::..:...: . ..:::. .. . ::..::::.:. ..::: :
NP_001 RKAPEINRGYFARVHGVSQLIKAFLR-----KTECHCQIVNLGAGMDTTFWRLKDEDLLP
70 80 90 100 110
110 120 130 140 150 160
pF1KSD RAAVWEVDFPDVARRKAERIGETPELCALTGPFERGEPASALCFESADYCILGLDLRQLQ
. .::::: .. :: . : .:
NP_001 -SKYFEVDFPMIVTRKLHSI-------------------------------------KL-
120 130
170 180 190 200 210 220
pF1KSD RVEEALGAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDA
::::.:: ::.:. ::..: :. :::. : :.:. :::. :
NP_001 ---------------PTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDR
140 150 160 170 180
230 240 250 260 270 280
pF1KSD FGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDINEFYHCFLPAEERRR
:::.:....:. . : :.: ..:.:..:.:. :: . .:::. :.:. :: : :
NP_001 FGQIMIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYN-RLPRAEVSR
190 200 210 220 230 240
290 300 310 320 330 340
pF1KSD VENIEPFDEFEEWHLKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPASVV
.:..: .::.: . :: . :..:
NP_001 IESLEFLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
250 260 270
>>XP_011544164 (OMIM: 610286) PREDICTED: leucine carboxy (302 aa)
initn: 459 init1: 295 opt: 350 Z-score: 429.6 bits: 88.7 E(85289): 3.4e-17
Smith-Waterman score: 430; 31.8% identity (56.5% similar) in 292 aa overlap (24-314:60-291)
10 20 30 40 50
pF1KSD MGPRSRERRAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVP-GAARRAPLI
.: .. :: .::. .: . :.:: :
XP_011 ILATLIGWTVRSFFLGRMETCCSHLGLRSGRRFAVSIGYWHDPYIQHFVRLSKERKAPEI
30 40 50 60 70 80
60 70 80 90 100 110
pF1KSD HRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWE
.:::..:...: . ..:::. .. . ::..::::.:. ..::: : . .:
XP_011 NRGYFARVHGVSQLIKAFLR-----KTECHCQIVNLGAGMDTTFWRLKDEDLLP-SKYFE
90 100 110 120 130 140
120 130 140 150 160 170
pF1KSD VDFPDVARRKAERIGETPELCALTGPFERGEPASALCFESADYCILGLDLRQLQRVEEAL
:::: .. :: . : .:
XP_011 VDFPMIVTRKLHSI-------------------------------------KL-------
150
180 190 200 210 220 230
pF1KSD GAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFML
::::.:: ::.:. ::..: :. :::. : :.:. :::. : :::.:.
XP_011 ---------PTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMI
160 170 180 190 200 210
240 250 260 270 280 290
pF1KSD QHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDINEFYHCFLPAEERRRVENIEP
...:. . : :.: ..:.:..:.:. :: . .:::. :.:. :: : :.:..:
XP_011 ENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYN-RLPRAEVSRIESLEF
220 230 240 250 260
300 310 320 330 340 350
pF1KSD FDEFEEWHLKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPASVVSSEGQV
.::.: . :: . :..:
XP_011 LDEMELLEQLMRHYCLCWATKGGNELGLKEITY
270 280 290 300
686 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 02:01:55 2016 done: Thu Nov 3 02:01:57 2016
Total Scan time: 8.850 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]