Result of FASTA (omim) for
pF1KSDA0414
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0414, 467 aa
1>>>pF1KSDA0414 467 - 467 aa - 467 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0978+/-0.000635; mu= 6.2018+/- 0.039
mean_var=482.9536+/-116.134, 0's: 0 Z-trim(114.4): 1391 B-trim: 1200 in 1/53
Lambda= 0.058361
statistics sampled from 22412 (24177) to 22412 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.283), width: 16
Scan time: 7.680
The best scores are: opt bits E(85289)
XP_011517001 (OMIM: 611692) PREDICTED: zinc finger ( 504) 630 68.8 4e-11
XP_005252046 (OMIM: 611692) PREDICTED: zinc finger ( 514) 630 68.8 4e-11
NP_001092740 (OMIM: 611692) zinc finger and BTB do ( 500) 627 68.5 4.7e-11
NP_005444 (OMIM: 611439) zinc finger and BTB domai ( 634) 513 59.1 4.1e-08
NP_001138810 (OMIM: 611439) zinc finger and BTB do ( 634) 513 59.1 4.1e-08
XP_005259778 (OMIM: 610672) PREDICTED: nucleus acc ( 527) 352 45.4 0.00045
NP_443108 (OMIM: 610672) nucleus accumbens-associa ( 527) 352 45.4 0.00045
XP_011516523 (OMIM: 615786) PREDICTED: nucleus acc ( 587) 338 44.3 0.0011
NP_653254 (OMIM: 615786) nucleus accumbens-associa ( 587) 338 44.3 0.0011
XP_006711419 (OMIM: 607646) PREDICTED: zinc finger ( 539) 328 43.4 0.0019
XP_006711421 (OMIM: 607646) PREDICTED: zinc finger ( 539) 328 43.4 0.0019
XP_006711416 (OMIM: 607646) PREDICTED: zinc finger ( 539) 328 43.4 0.0019
XP_006711420 (OMIM: 607646) PREDICTED: zinc finger ( 539) 328 43.4 0.0019
XP_006711422 (OMIM: 607646) PREDICTED: zinc finger ( 539) 328 43.4 0.0019
XP_006711417 (OMIM: 607646) PREDICTED: zinc finger ( 539) 328 43.4 0.0019
XP_006711412 (OMIM: 607646) PREDICTED: zinc finger ( 539) 328 43.4 0.0019
XP_011507901 (OMIM: 607646) PREDICTED: zinc finger ( 539) 328 43.4 0.0019
NP_001243384 (OMIM: 607646) zinc finger and BTB do ( 539) 328 43.4 0.0019
NP_001239335 (OMIM: 607646) zinc finger and BTB do ( 573) 328 43.4 0.0019
XP_011507900 (OMIM: 607646) PREDICTED: zinc finger ( 573) 328 43.4 0.0019
XP_016856888 (OMIM: 607646) PREDICTED: zinc finger ( 630) 328 43.5 0.002
NP_006617 (OMIM: 605976) zinc finger and BTB domai ( 424) 319 42.5 0.0028
XP_011525788 (OMIM: 608640) PREDICTED: zinc finger ( 436) 308 41.6 0.0054
NP_001309757 (OMIM: 608640) zinc finger protein 46 ( 475) 308 41.6 0.0056
NP_001309756 (OMIM: 608640) zinc finger protein 46 ( 509) 308 41.7 0.0058
NP_001309755 (OMIM: 608640) zinc finger protein 46 ( 509) 308 41.7 0.0058
XP_016882959 (OMIM: 608640) PREDICTED: zinc finger ( 519) 308 41.7 0.0058
NP_001309752 (OMIM: 608640) zinc finger protein 46 ( 532) 308 41.7 0.0059
NP_001309754 (OMIM: 608640) zinc finger protein 46 ( 532) 308 41.7 0.0059
NP_001284552 (OMIM: 608640) zinc finger protein 46 ( 540) 308 41.7 0.006
NP_001309750 (OMIM: 608640) zinc finger protein 46 ( 557) 308 41.7 0.006
NP_694989 (OMIM: 608640) zinc finger protein 461 i ( 563) 308 41.7 0.0061
XP_016870103 (OMIM: 616290) PREDICTED: zinc finger (1059) 310 42.4 0.0073
NP_149350 (OMIM: 616290) zinc finger protein 658 [ (1059) 310 42.4 0.0073
XP_011543981 (OMIM: 616290) PREDICTED: zinc finger (1059) 310 42.4 0.0073
XP_005272572 (OMIM: 616290) PREDICTED: zinc finger (1059) 310 42.4 0.0073
NP_001304845 (OMIM: 616290) zinc finger protein 65 (1059) 310 42.4 0.0073
>>XP_011517001 (OMIM: 611692) PREDICTED: zinc finger and (504 aa)
initn: 784 init1: 406 opt: 630 Z-score: 320.8 bits: 68.8 E(85289): 4e-11
Smith-Waterman score: 631; 30.3% identity (58.3% similar) in 465 aa overlap (1-447:3-451)
10 20 30 40 50
pF1KSD MEPGTNSF-RVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPY
.: ..:: . . :..:::.:..::. : ::.:::. . .::. ::::::::::::::
XP_011 MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD FCDQVLLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVD
: :. :.. . . . :: :::..: ::::. . ..::.::::::::: :.:
XP_011 FRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVID
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD KCTEVLEG-NPTVLCQKLNHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGEN
:::..::. . . .. . . : ::. .: ... . . : .. :
XP_011 KCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGR----
130 140 150 160 170
180 190 200 210 220 230
pF1KSD EEESTKDELSSQLTEHEYLPSNSSTEHDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPS
. ::.: . : ::.. ..::. : :. : :. . :.. . . .
XP_011 -----QPTASSDL-RMETTPSKAL--RSRLQEEGHSDRGSSGSVSEYEIQIEGD-HEQGD
180 190 200 210 220
240 250 260 270 280 290
pF1KSD IMAHKRWI---HVKPERLEQ-ACEGMDVHATYDEHQVTESINTVQTEHT-VQPSGVEEDF
..... : .:: :. .. .: : . :. :: .. :. . : : .
XP_011 LLVRESQITEVKVKMEKSDRPSCS--DSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQH
230 240 250 260 270 280
300 310 320 330 340
pF1KSD HIGEKKVEAEFDEQADESNYDEQVDFYGSSMEEFSGERSDG----NLIGHRQEAALAAGY
. ... .. . .. . . . : . : : :. .. : . .:. :
XP_011 AYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQG-
290 300 310 320 330 340
350 360 370 380 390 400
pF1KSD SENIEMVTGIKEEASHLGFSATDKLYP------C-QCGKSFTHKSQRDRHMSMHLGLRPY
:.. :... :.: :: . :: : :::::..:.. :::: .:.:. :.
XP_011 SDSEAMMNNPGYESSPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPF
350 360 370 380 390 400
410 420 430 440 450 460
pF1KSD GCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEAAKAE
: ::::. : .: :.. :: ::..:.::.: : .. ....:.
XP_011 VCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSR
410 420 430 440 450 460
pF1KSD QNTTEAN
XP_011 IESPERTDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD
470 480 490 500
>>XP_005252046 (OMIM: 611692) PREDICTED: zinc finger and (514 aa)
initn: 784 init1: 406 opt: 630 Z-score: 320.7 bits: 68.8 E(85289): 4e-11
Smith-Waterman score: 631; 30.3% identity (58.3% similar) in 465 aa overlap (1-447:13-461)
10 20 30 40
pF1KSD MEPGTNSF-RVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAH
.: ..:: . . :..:::.:..::. : ::.:::. . .::. ::::
XP_005 MEECKSRVRFMSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD KAVLAASSPYFCDQVLLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAA
::::::::::: :. :.. . . . :: :::..: ::::. . ..::.::::
XP_005 KAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD SFLQMWHVVDKCTEVLEG-NPTVLCQKLNHGSDHQSPSSSSYNGLVESFELGSGGHTDFP
::::: :.::::..::. . . .. . . : ::. .: ... . . :
XP_005 SFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD KAQELRDGENEEESTKDELSSQLTEHEYLPSNSSTEHDRLSTEMASQDGEEGASDSAEFH
.. : . ::.: . : ::.. ..::. : :. : :. . :..
XP_005 YCSQGR---------QPTASSDL-RMETTPSKAL--RSRLQEEGHSDRGSSGSVSEYEIQ
190 200 210 220
230 240 250 260 270 280
pF1KSD YTRPMYSKPSIMAHKRWI---HVKPERLEQ-ACEGMDVHATYDEHQVTESINTVQTEHT-
. . ...... : .:: :. .. .: : . :. :: .. :. .
XP_005 IEGD-HEQGDLLVRESQITEVKVKMEKSDRPSCS--DSSSLGDDGYHTEMVDGEQVVAVN
230 240 250 260 270 280
290 300 310 320 330
pF1KSD VQPSGVEEDFHIGEKKVEAEFDEQADESNYDEQVDFYGSSMEEFSGERSDG----NLIGH
: : . . ... .. . .. . . . : . : : :. .. :
XP_005 VGSYGSVLQHAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLH
290 300 310 320 330 340
340 350 360 370 380 390
pF1KSD RQEAALAAGYSENIEMVTGIKEEASHLGFSATDKLYP------C-QCGKSFTHKSQRDRH
. .:. : :.. :... :.: :: . :: : :::::..:.. :::
XP_005 SDLQGLVQG-SDSEAMMNNPGYESSPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRH
350 360 370 380 390 400
400 410 420 430 440 450
pF1KSD MSMHLGLRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSC
: .:.:. :. : ::::. : .: :.. :: ::..:.::.: : .. ....:.
XP_005 MRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKN
410 420 430 440 450 460
460
pF1KSD TKSYEAAKAEQNTTEAN
XP_005 HPGVAEVRSRIESPERTDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD
470 480 490 500 510
>>NP_001092740 (OMIM: 611692) zinc finger and BTB domain (500 aa)
initn: 784 init1: 406 opt: 627 Z-score: 319.4 bits: 68.5 E(85289): 4.7e-11
Smith-Waterman score: 628; 30.4% identity (58.4% similar) in 461 aa overlap (5-447:3-447)
10 20 30 40 50
pF1KSD MEPGTNSF-RVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFC
..:: . . :..:::.:..::. : ::.:::. . .::. :::::::::::::::
NP_001 MDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFR
10 20 30 40 50
60 70 80 90 100 110
pF1KSD DQVLLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKC
:. :.. . . . :: :::..: ::::. . ..::.::::::::: :.:::
NP_001 DHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD TEVLEG-NPTVLCQKLNHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGENEE
:..::. . . .. . . : ::. .: ... . . : .. :
NP_001 TQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGR------
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD ESTKDELSSQLTEHEYLPSNSSTEHDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPSIM
. ::.: . : ::.. ..::. : :. : :. . :.. . . ...
NP_001 ---QPTASSDL-RMETTPSKAL--RSRLQEEGHSDRGSSGSVSEYEIQIEGD-HEQGDLL
180 190 200 210 220
240 250 260 270 280 290
pF1KSD AHKRWI---HVKPERLEQ-ACEGMDVHATYDEHQVTESINTVQTEHT-VQPSGVEEDFHI
... : .:: :. .. .: : . :. :: .. :. . : : .
NP_001 VRESQITEVKVKMEKSDRPSCS--DSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAY
230 240 250 260 270 280
300 310 320 330 340
pF1KSD GEKKVEAEFDEQADESNYDEQVDFYGSSMEEFSGERSDG----NLIGHRQEAALAAGYSE
. ... .. . .. . . . : . : : :. .. : . .:. : :.
NP_001 SYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQG-SD
290 300 310 320 330 340
350 360 370 380 390 400
pF1KSD NIEMVTGIKEEASHLGFSATDKLYP------C-QCGKSFTHKSQRDRHMSMHLGLRPYGC
. :... :.: :: . :: : :::::..:.. :::: .:.:. :. :
NP_001 SEAMMNNPGYESSPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVC
350 360 370 380 390 400
410 420 430 440 450 460
pF1KSD GVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEAAKAEQN
::::. : .: :.. :: ::..:.::.: : .. ....:.
NP_001 KFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIE
410 420 430 440 450 460
pF1KSD TTEAN
NP_001 SPERTDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD
470 480 490 500
>>NP_005444 (OMIM: 611439) zinc finger and BTB domain-co (634 aa)
initn: 1074 init1: 510 opt: 513 Z-score: 266.7 bits: 59.1 E(85289): 4.1e-08
Smith-Waterman score: 693; 34.7% identity (57.0% similar) in 505 aa overlap (3-410:27-523)
10 20 30
pF1KSD MEPGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVS
:.. .: ::. .:..:..::::: ::::::::
NP_005 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD IVVQGHIFRAHKAVLAASSPYFCDQVLLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMP
: :::. ::::.:::::::::: ::::::. : ::.::.: .::..: :.::::: :
NP_005 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
70 80 90 100 110 120
100 110 120
pF1KSD APEIVSYLTAASFLQMWHVVDKCTEVL-EGN-----------------------------
: .::..::..: :::::.::::::.: ::
NP_005 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
130 140 150 160 170 180
130 140 150 160 170 180
pF1KSD --PTVLCQKLNHGS----DHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGENEEES
:... . .:.: ..::::::.: . :: ...:... : . : .:...
NP_005 VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAV---GSGERRG
190 200 210 220 230
190 200 210 220 230
pF1KSD TKDELSSQLTEHEYLPSNSST-EHDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPSIMA
. . .. :.. : :.: . . ::. .. .: .. :: :. ::::
NP_005 GGPVFPAPVVGSGGATSGKLLLEADELCDD--GGDGRGAVVPGAGLR--RPTYTPPSIMP
240 250 260 270 280 290
240 250 260
pF1KSD HKRWIHVK------------PER--LEQACEGMDVHAT----YDEH-------------Q
.:.:..:: :. ::. : :. : ::. .
NP_005 QKHWVYVKRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPE
300 310 320 330 340 350
270 280 290 300 310
pF1KSD VTESINTVQTEHTVQPSGVEE--------DF--HIGEKKVEAEFDEQADE--SNYDEQ--
.: ::. :.: .: :. :: . : : : .:... :.: .
NP_005 ATLSISDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPV-AGLDDSGGPTPSSYAPSHP
360 370 380 390 400 410
320 330 340 350
pF1KSD ------VDFYGSSMEEF------SGERSDGNLIGHRQE--AALAAGYSENIEMVTG-IKE
.:. :... : :. .. :. :.. : :. ..: : . : : .
NP_005 PRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGG
420 430 440 450 460 470
360 370 380 390 400 410
pF1KSD EASHLGFSATDKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHM
. : . .:.. :.:::.:.:::.::::..:::.:::. : ::.::::
NP_005 VPGGTGSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHM
480 490 500 510 520 530
420 430 440 450 460
pF1KSD KIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEAAKAEQNTTEAN
NP_005 KTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRES
540 550 560 570 580 590
>>NP_001138810 (OMIM: 611439) zinc finger and BTB domain (634 aa)
initn: 1074 init1: 510 opt: 513 Z-score: 266.7 bits: 59.1 E(85289): 4.1e-08
Smith-Waterman score: 693; 34.7% identity (57.0% similar) in 505 aa overlap (3-410:27-523)
10 20 30
pF1KSD MEPGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVS
:.. .: ::. .:..:..::::: ::::::::
NP_001 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD IVVQGHIFRAHKAVLAASSPYFCDQVLLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMP
: :::. ::::.:::::::::: ::::::. : ::.::.: .::..: :.::::: :
NP_001 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
70 80 90 100 110 120
100 110 120
pF1KSD APEIVSYLTAASFLQMWHVVDKCTEVL-EGN-----------------------------
: .::..::..: :::::.::::::.: ::
NP_001 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
130 140 150 160 170 180
130 140 150 160 170 180
pF1KSD --PTVLCQKLNHGS----DHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGENEEES
:... . .:.: ..::::::.: . :: ...:... : . : .:...
NP_001 VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAV---GSGERRG
190 200 210 220 230
190 200 210 220 230
pF1KSD TKDELSSQLTEHEYLPSNSST-EHDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPSIMA
. . .. :.. : :.: . . ::. .. .: .. :: :. ::::
NP_001 GGPVFPAPVVGSGGATSGKLLLEADELCDD--GGDGRGAVVPGAGLR--RPTYTPPSIMP
240 250 260 270 280 290
240 250 260
pF1KSD HKRWIHVK------------PER--LEQACEGMDVHAT----YDEH-------------Q
.:.:..:: :. ::. : :. : ::. .
NP_001 QKHWVYVKRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPE
300 310 320 330 340 350
270 280 290 300 310
pF1KSD VTESINTVQTEHTVQPSGVEE--------DF--HIGEKKVEAEFDEQADE--SNYDEQ--
.: ::. :.: .: :. :: . : : : .:... :.: .
NP_001 ATLSISDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPV-AGLDDSGGPTPSSYAPSHP
360 370 380 390 400 410
320 330 340 350
pF1KSD ------VDFYGSSMEEF------SGERSDGNLIGHRQE--AALAAGYSENIEMVTG-IKE
.:. :... : :. .. :. :.. : :. ..: : . : : .
NP_001 PRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGG
420 430 440 450 460 470
360 370 380 390 400 410
pF1KSD EASHLGFSATDKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHM
. : . .:.. :.:::.:.:::.::::..:::.:::. : ::.::::
NP_001 VPGGTGSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHM
480 490 500 510 520 530
420 430 440 450 460
pF1KSD KIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEAAKAEQNTTEAN
NP_001 KTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRES
540 550 560 570 580 590
>>XP_005259778 (OMIM: 610672) PREDICTED: nucleus accumbe (527 aa)
initn: 355 init1: 329 opt: 352 Z-score: 194.1 bits: 45.4 E(85289): 0.00045
Smith-Waterman score: 352; 36.0% identity (69.7% similar) in 178 aa overlap (7-182:4-177)
10 20 30 40 50 60
pF1KSD MEPGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCD
....:.:.:...::. ::.:: :: ::::.::.:: :.::.::::::: :: :
XP_005 MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRD
10 20 30 40 50
70 80 90 100 110
pF1KSD QVLLKNSRRIV--LPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDK
:..::: : :: ...:. :..:: ::::: : . . . .:.:::. ....:
XP_005 --LFNNSRSAVVELPAAVQPQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD CTEVLEGNPTVLCQKLNHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGENEE
:: . . :.. . .. ..::: . .... . . : .: ..... ..:
XP_005 GTEFFLKVSSPSCDSQGLHAE-EAPSSEPQSPVAQTSGWPACS-TPLPLVSRVKTEQQES
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD ESTKDELSSQLTEHEYLPSNSSTEHDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPSIM
.:..
XP_005 DSVQCMPVAKRLWDSGQKEAGGGGNGSRKMAKFSTPDLAANRPHQPPPPQQAPVVAAAQP
180 190 200 210 220 230
>>NP_443108 (OMIM: 610672) nucleus accumbens-associated (527 aa)
initn: 355 init1: 329 opt: 352 Z-score: 194.1 bits: 45.4 E(85289): 0.00045
Smith-Waterman score: 352; 36.0% identity (69.7% similar) in 178 aa overlap (7-182:4-177)
10 20 30 40 50 60
pF1KSD MEPGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCD
....:.:.:...::. ::.:: :: ::::.::.:: :.::.::::::: :: :
NP_443 MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRD
10 20 30 40 50
70 80 90 100 110
pF1KSD QVLLKNSRRIV--LPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDK
:..::: : :: ...:. :..:: ::::: : . . . .:.:::. ....:
NP_443 --LFNNSRSAVVELPAAVQPQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD CTEVLEGNPTVLCQKLNHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGENEE
:: . . :.. . .. ..::: . .... . . : .: ..... ..:
NP_443 GTEFFLKVSSPSCDSQGLHAE-EAPSSEPQSPVAQTSGWPACS-TPLPLVSRVKTEQQES
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD ESTKDELSSQLTEHEYLPSNSSTEHDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPSIM
.:..
NP_443 DSVQCMPVAKRLWDSGQKEAGGGGNGSRKMAKFSTPDLAANRPHQPPPPQQAPVVAAAQP
180 190 200 210 220 230
>>XP_011516523 (OMIM: 615786) PREDICTED: nucleus accumbe (587 aa)
initn: 284 init1: 284 opt: 338 Z-score: 187.3 bits: 44.3 E(85289): 0.0011
Smith-Waterman score: 338; 42.3% identity (67.6% similar) in 142 aa overlap (8-143:5-145)
10 20 30 40 50 60
pF1KSD MEPGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCD
...:.:.:..:.: ::.:: : :::::::.:. :.::.::::::: :: :
XP_011 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRD
10 20 30 40 50
70 80 90 100 110
pF1KSD QVLLKNSRRIV-LPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKC
.. ::. :: . : :..:: :::::.: : : . . .:.:::. :.:..
XP_011 -LFSGNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD TEVLEGNPTVLCQKL-----NHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDG
:... . :.. . ::. :::
XP_011 TDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHE
120 130 140 150 160 170
>>NP_653254 (OMIM: 615786) nucleus accumbens-associated (587 aa)
initn: 284 init1: 284 opt: 338 Z-score: 187.3 bits: 44.3 E(85289): 0.0011
Smith-Waterman score: 338; 42.3% identity (67.6% similar) in 142 aa overlap (8-143:5-145)
10 20 30 40 50 60
pF1KSD MEPGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCD
...:.:.:..:.: ::.:: : :::::::.:. :.::.::::::: :: :
NP_653 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRD
10 20 30 40 50
70 80 90 100 110
pF1KSD QVLLKNSRRIV-LPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKC
.. ::. :: . : :..:: :::::.: : : . . .:.:::. :.:..
NP_653 -LFSGNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD TEVLEGNPTVLCQKL-----NHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDG
:... . :.. . ::. :::
NP_653 TDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHE
120 130 140 150 160 170
>>XP_006711419 (OMIM: 607646) PREDICTED: zinc finger and (539 aa)
initn: 689 init1: 231 opt: 328 Z-score: 183.1 bits: 43.4 E(85289): 0.0019
Smith-Waterman score: 409; 25.3% identity (51.7% similar) in 482 aa overlap (3-447:4-449)
10 20 30 40 50
pF1KSD MEPGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFC
: . . . ::: :: .:. ::.::: :.:::..: .:: .:.:.::::: : ::
XP_006 MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYF-
10 20 30 40 50
60 70 80 90 100
pF1KSD DQVLLKNSRRIVLP------------------DVMNPRVFENILLSSYTGRLVMPAPEIV
... ... :. : ..:... .: .::. :. . ..
XP_006 KKLFTEGGGGAVMGAGGSGTATGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMP
60 70 80 90 100 110
110 120 130 140 150
pF1KSD SYLTAASFLQMWHVVDKCTEVLEGN----PTVL---CQKLNHGSDHQSPSSSSY--NGLV
. : :: .:.. :. : :.:.:. :. :.. . . . ...: ::
XP_006 AVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATASGVPNGED
120 130 140 150 160 170
160 170 180 190 200
pF1KSD ESFELG---SGGHTDFPKAQELRDGENEEESTKDELSSQLT-EHEYLPSNSSTEHDRLST
.. : :.. : .. .:: ...:. : .:.. : ...
XP_006 SPPQVPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPAHPLTYEEE---
180 190 200 210 220 230
210 220 230 240 250 260
pF1KSD EMASQDGEEGASDSAEFHYTRPMYSKPSIMAHKRWIHVKPERLEQACEGMDVHATYDEHQ
:.:.. : :.: .. :: :. : .: . : .:. ..
XP_006 EVAGRVGSSGGSGPGD------SYSPPTGTA-------SPPEGPQ---------SYEPYE
240 250 260 270
270 280 290 300 310 320
pF1KSD VTESINTVQTEHTVQPS--GVEEDFHIGEKKVEAEFDEQADESNYDEQVDFYGSSMEEFS
: . :. : : :. . : . : . .::. : .. : ::... .
XP_006 GEE-----EEEELVYPPAYGLAQG---GGPPLSPE-ELGSDEDAIDPDLMAYLSSLHQDN
280 290 300 310 320
330 340 350 360 370 380
pF1KSD ---GERSDGNLIGHRQEAALAAGYSENIEMVTGIKEEASHLGFSATDKLYPCQ-CGKSFT
: :. .:. .:. . . ... : . :. . .: . :. :: ::
XP_006 LAPGLDSQDKLVRKRR-SQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFT
330 340 350 360 370 380
390 400 410 420 430 440
pF1KSD HKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDS
.... :: : : :::.: : .: .. : .::..::: .::::..: : : .:
XP_006 RNDKLKIHMRKHTGERPYSCPHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDH
390 400 410 420 430 440
450 460
pF1KSD FHRHVTSCTKSYEAAKAEQNTTEAN
..::.
XP_006 LQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSTAAASPAGLDLSNGHLDTFRLSLARFWEQ
450 460 470 480 490 500
467 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:38:33 2016 done: Thu Nov 3 01:38:35 2016
Total Scan time: 7.680 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]