Result of FASTA (omim) for
pF1KSDA0388
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0388, 747 aa
1>>>pF1KSDA0388 747 - 747 aa - 747 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5493+/-0.000415; mu= 15.5230+/- 0.026
mean_var=143.9707+/-27.585, 0's: 0 Z-trim(116.7): 179 B-trim: 227 in 1/54
Lambda= 0.106890
statistics sampled from 27862 (28043) to 27862 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.329), width: 16
Scan time: 11.760
The best scores are: opt bits E(85289)
NP_001982 (OMIM: 601674) histone-lysine N-methyltr ( 747) 5206 815.3 0
NP_001308008 (OMIM: 601674) histone-lysine N-methy ( 753) 5206 815.3 0
NP_001308010 (OMIM: 601674) histone-lysine N-methy ( 738) 4666 732.0 2.1e-210
XP_011522819 (OMIM: 601674) PREDICTED: histone-lys ( 744) 4666 732.0 2.1e-210
XP_016879839 (OMIM: 601674) PREDICTED: histone-lys ( 668) 4664 731.6 2.4e-210
NP_001308011 (OMIM: 601674) histone-lysine N-methy ( 707) 4383 688.3 2.8e-197
XP_005257202 (OMIM: 601674) PREDICTED: histone-lys ( 713) 4383 688.3 2.8e-197
XP_016879840 (OMIM: 601674) PREDICTED: histone-lys ( 637) 4382 688.1 2.9e-197
XP_016879841 (OMIM: 601674) PREDICTED: histone-lys ( 410) 2879 456.2 1.3e-127
NP_001190176 (OMIM: 277590,601573) histone-lysine ( 746) 2701 429.0 3.5e-119
XP_005250019 (OMIM: 277590,601573) PREDICTED: hist ( 754) 2701 429.0 3.5e-119
XP_011514186 (OMIM: 277590,601573) PREDICTED: hist ( 751) 2624 417.1 1.3e-115
NP_004447 (OMIM: 277590,601573) histone-lysine N-m ( 751) 2624 417.1 1.3e-115
XP_011514185 (OMIM: 277590,601573) PREDICTED: hist ( 759) 2624 417.1 1.3e-115
XP_016867306 (OMIM: 277590,601573) PREDICTED: hist ( 759) 2624 417.1 1.3e-115
XP_011514189 (OMIM: 277590,601573) PREDICTED: hist ( 742) 2599 413.2 1.9e-114
XP_011514190 (OMIM: 277590,601573) PREDICTED: hist ( 742) 2599 413.2 1.9e-114
XP_011514187 (OMIM: 277590,601573) PREDICTED: hist ( 750) 2599 413.2 1.9e-114
NP_001190177 (OMIM: 277590,601573) histone-lysine ( 737) 2491 396.6 1.9e-109
XP_005250020 (OMIM: 277590,601573) PREDICTED: hist ( 745) 2491 396.6 2e-109
XP_016867307 (OMIM: 277590,601573) PREDICTED: hist ( 738) 2487 396.0 3e-109
XP_016867310 (OMIM: 277590,601573) PREDICTED: hist ( 637) 2420 385.6 3.5e-106
XP_011514193 (OMIM: 277590,601573) PREDICTED: hist ( 718) 2413 384.5 8e-106
XP_011514191 (OMIM: 277590,601573) PREDICTED: hist ( 729) 2410 384.1 1.1e-105
XP_011514188 (OMIM: 277590,601573) PREDICTED: hist ( 743) 2410 384.1 1.1e-105
NP_694543 (OMIM: 277590,601573) histone-lysine N-m ( 707) 2354 375.4 4.3e-103
XP_011514195 (OMIM: 277590,601573) PREDICTED: hist ( 715) 2354 375.4 4.4e-103
XP_011514199 (OMIM: 277590,601573) PREDICTED: hist ( 642) 2343 373.7 1.3e-102
XP_011514200 (OMIM: 277590,601573) PREDICTED: hist ( 642) 2343 373.7 1.3e-102
XP_011514196 (OMIM: 277590,601573) PREDICTED: hist ( 712) 2266 361.9 5.3e-99
XP_011514192 (OMIM: 277590,601573) PREDICTED: hist ( 720) 2266 361.9 5.3e-99
XP_016867309 (OMIM: 277590,601573) PREDICTED: hist ( 703) 2260 360.9 9.9e-99
XP_011514197 (OMIM: 277590,601573) PREDICTED: hist ( 711) 2260 360.9 1e-98
XP_011514198 (OMIM: 277590,601573) PREDICTED: hist ( 673) 1262 207.0 2.1e-52
NP_001190178 (OMIM: 277590,601573) histone-lysine ( 695) 1262 207.0 2.1e-52
XP_005250021 (OMIM: 277590,601573) PREDICTED: hist ( 703) 1262 207.0 2.1e-52
XP_016867308 (OMIM: 277590,601573) PREDICTED: hist ( 712) 1262 207.0 2.1e-52
XP_011514194 (OMIM: 277590,601573) PREDICTED: hist ( 717) 1262 207.0 2.2e-52
XP_011514203 (OMIM: 277590,601573) PREDICTED: hist ( 432) 736 125.7 3.9e-28
XP_011514201 (OMIM: 277590,601573) PREDICTED: hist ( 511) 736 125.8 4.4e-28
NP_003164 (OMIM: 300254) histone-lysine N-methyltr ( 412) 347 65.7 4.4e-10
NP_001269095 (OMIM: 300254) histone-lysine N-methy ( 423) 347 65.7 4.4e-10
XP_016864077 (OMIM: 194190,602952) PREDICTED: hist ( 584) 347 65.9 5.6e-10
XP_016864076 (OMIM: 194190,602952) PREDICTED: hist ( 584) 347 65.9 5.6e-10
XP_011511862 (OMIM: 194190,602952) PREDICTED: hist ( 584) 347 65.9 5.6e-10
NP_075447 (OMIM: 607083) histone-lysine N-methyltr (1437) 351 66.9 6.8e-10
XP_005248059 (OMIM: 194190,602952) PREDICTED: hist (1296) 347 66.2 9.7e-10
NP_001035889 (OMIM: 194190,602952) histone-lysine (1365) 347 66.2 1e-09
NP_579878 (OMIM: 194190,602952) histone-lysine N-m (1365) 347 66.2 1e-09
XP_011511859 (OMIM: 194190,602952) PREDICTED: hist (1365) 347 66.2 1e-09
>>NP_001982 (OMIM: 601674) histone-lysine N-methyltransf (747 aa)
initn: 5206 init1: 5206 opt: 5206 Z-score: 4348.4 bits: 815.3 E(85289): 0
Smith-Waterman score: 5206; 100.0% identity (100.0% similar) in 747 aa overlap (1-747:1-747)
10 20 30 40 50 60
pF1KSD MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
670 680 690 700 710 720
730 740
pF1KSD EELFFDYRYSQADALKYVGIERETDVL
:::::::::::::::::::::::::::
NP_001 EELFFDYRYSQADALKYVGIERETDVL
730 740
>>NP_001308008 (OMIM: 601674) histone-lysine N-methyltra (753 aa)
initn: 5206 init1: 5206 opt: 5206 Z-score: 4348.4 bits: 815.3 E(85289): 0
Smith-Waterman score: 5206; 100.0% identity (100.0% similar) in 747 aa overlap (1-747:7-753)
10 20 30 40 50
pF1KSD MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEDYSKMEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD ILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSW
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD SPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
670 680 690 700 710 720
720 730 740
pF1KSD RAIQAGEELFFDYRYSQADALKYVGIERETDVL
:::::::::::::::::::::::::::::::::
NP_001 RAIQAGEELFFDYRYSQADALKYVGIERETDVL
730 740 750
>>NP_001308010 (OMIM: 601674) histone-lysine N-methyltra (738 aa)
initn: 4664 init1: 4664 opt: 4666 Z-score: 3898.4 bits: 732.0 E(85289): 2.1e-210
Smith-Waterman score: 5115; 98.8% identity (98.8% similar) in 747 aa overlap (1-747:1-738)
10 20 30 40 50 60
pF1KSD MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 KKLRVQPVQSMKP---------CTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
70 80 90 100 110
130 140 150 160 170 180
pF1KSD FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
480 490 500 510 520 530
550 560 570 580 590 600
pF1KSD QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
540 550 560 570 580 590
610 620 630 640 650 660
pF1KSD SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
600 610 620 630 640 650
670 680 690 700 710 720
pF1KSD KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
660 670 680 690 700 710
730 740
pF1KSD EELFFDYRYSQADALKYVGIERETDVL
:::::::::::::::::::::::::::
NP_001 EELFFDYRYSQADALKYVGIERETDVL
720 730
>>XP_011522819 (OMIM: 601674) PREDICTED: histone-lysine (744 aa)
initn: 4664 init1: 4664 opt: 4666 Z-score: 3898.4 bits: 732.0 E(85289): 2.1e-210
Smith-Waterman score: 5115; 98.8% identity (98.8% similar) in 747 aa overlap (1-747:7-744)
10 20 30 40 50
pF1KSD MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEDYSKMEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD ILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSW
::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 ILNEEWKKLRVQPVQSMKP---------CTIESIFPGFASQHMLMRSLNTVALVPIMYSW
70 80 90 100 110
120 130 140 150 160 170
pF1KSD SPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KSD SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
360 370 380 390 400 410
420 430 440 450 460 470
pF1KSD ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
420 430 440 450 460 470
480 490 500 510 520 530
pF1KSD ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
480 490 500 510 520 530
540 550 560 570 580 590
pF1KSD CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
540 550 560 570 580 590
600 610 620 630 640 650
pF1KSD WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
600 610 620 630 640 650
660 670 680 690 700 710
pF1KSD RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
660 670 680 690 700 710
720 730 740
pF1KSD RAIQAGEELFFDYRYSQADALKYVGIERETDVL
:::::::::::::::::::::::::::::::::
XP_011 RAIQAGEELFFDYRYSQADALKYVGIERETDVL
720 730 740
>>XP_016879839 (OMIM: 601674) PREDICTED: histone-lysine (668 aa)
initn: 4664 init1: 4664 opt: 4664 Z-score: 3897.3 bits: 731.6 E(85289): 2.4e-210
Smith-Waterman score: 4664; 99.7% identity (99.9% similar) in 668 aa overlap (80-747:1-668)
50 60 70 80 90 100
pF1KSD QEKTQILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVP
.: :::::::::::::::::::::::::::
XP_016 MKPCTIESIFPGFASQHMLMRSLNTVALVP
10 20 30
110 120 130 140 150 160
pF1KSD IMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSV
40 50 60 70 80 90
170 180 190 200 210 220
pF1KSD LISDAVFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISDAVFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKK
100 110 120 130 140 150
230 240 250 260 270 280
pF1KSD QFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQ
160 170 180 190 200 210
290 300 310 320 330 340
pF1KSD SLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAM
220 230 240 250 260 270
350 360 370 380 390 400
pF1KSD LHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQT
280 290 300 310 320 330
410 420 430 440 450 460
pF1KSD PTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVF
340 350 360 370 380 390
470 480 490 500 510 520
pF1KSD QFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDR
400 410 420 430 440 450
530 540 550 560 570 580
pF1KSD PCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTC
460 470 480 490 500 510
590 600 610 620 630 640
pF1KSD GASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQ
520 530 540 550 560 570
650 660 670 680 690 700
pF1KSD DEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRI
580 590 600 610 620 630
710 720 730 740
pF1KSD GIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL
::::::::::::::::::::::::::::::::::::::
XP_016 GIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL
640 650 660
>>NP_001308011 (OMIM: 601674) histone-lysine N-methyltra (707 aa)
initn: 4382 init1: 4382 opt: 4383 Z-score: 3662.8 bits: 688.3 E(85289): 2.8e-197
Smith-Waterman score: 4842; 94.6% identity (94.6% similar) in 747 aa overlap (1-747:1-707)
10 20 30 40 50 60
pF1KSD MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
::::::::::::::::::::::
NP_001 KKLRVQPVQSMKPVSGHPFLKK--------------------------------------
70 80
130 140 150 160 170 180
pF1KSD FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --VEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
90 100 110 120 130 140
190 200 210 220 230 240
pF1KSD DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
150 160 170 180 190 200
250 260 270 280 290 300
pF1KSD ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
210 220 230 240 250 260
310 320 330 340 350 360
pF1KSD RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
270 280 290 300 310 320
370 380 390 400 410 420
pF1KSD RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
330 340 350 360 370 380
430 440 450 460 470 480
pF1KSD QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
390 400 410 420 430 440
490 500 510 520 530 540
pF1KSD LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
450 460 470 480 490 500
550 560 570 580 590 600
pF1KSD QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
510 520 530 540 550 560
610 620 630 640 650 660
pF1KSD SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
570 580 590 600 610 620
670 680 690 700 710 720
pF1KSD KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
630 640 650 660 670 680
730 740
pF1KSD EELFFDYRYSQADALKYVGIERETDVL
:::::::::::::::::::::::::::
NP_001 EELFFDYRYSQADALKYVGIERETDVL
690 700
>>XP_005257202 (OMIM: 601674) PREDICTED: histone-lysine (713 aa)
initn: 4382 init1: 4382 opt: 4383 Z-score: 3662.7 bits: 688.3 E(85289): 2.8e-197
Smith-Waterman score: 4842; 94.6% identity (94.6% similar) in 747 aa overlap (1-747:7-713)
10 20 30 40 50
pF1KSD MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEDYSKMEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD ILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSW
::::::::::::::::::::::::::::
XP_005 ILNEEWKKLRVQPVQSMKPVSGHPFLKK--------------------------------
70 80
120 130 140 150 160 170
pF1KSD SPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 --------VEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
90 100 110 120 130 140
180 190 200 210 220 230
pF1KSD VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
150 160 170 180 190 200
240 250 260 270 280 290
pF1KSD MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
210 220 230 240 250 260
300 310 320 330 340 350
pF1KSD HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
270 280 290 300 310 320
360 370 380 390 400 410
pF1KSD SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
330 340 350 360 370 380
420 430 440 450 460 470
pF1KSD ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
390 400 410 420 430 440
480 490 500 510 520 530
pF1KSD ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
450 460 470 480 490 500
540 550 560 570 580 590
pF1KSD CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
510 520 530 540 550 560
600 610 620 630 640 650
pF1KSD WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
570 580 590 600 610 620
660 670 680 690 700 710
pF1KSD RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
630 640 650 660 670 680
720 730 740
pF1KSD RAIQAGEELFFDYRYSQADALKYVGIERETDVL
:::::::::::::::::::::::::::::::::
XP_005 RAIQAGEELFFDYRYSQADALKYVGIERETDVL
690 700 710
>>XP_016879840 (OMIM: 601674) PREDICTED: histone-lysine (637 aa)
initn: 4454 init1: 4382 opt: 4382 Z-score: 3662.5 bits: 688.1 E(85289): 2.9e-197
Smith-Waterman score: 4382; 100.0% identity (100.0% similar) in 625 aa overlap (123-747:13-637)
100 110 120 130 140 150
pF1KSD ASQHMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELIN
::::::::::::::::::::::::::::::
XP_016 MKPVSGHPFLKKVEDETVLCNIPYMGDEVKEEDETFIEELIN
10 20 30 40
160 170 180 190 200 210
pF1KSD NYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVT
50 60 70 80 90 100
220 230 240 250 260 270
pF1KSD RKRKRHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKRKRHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQ
110 120 130 140 150 160
280 290 300 310 320 330
pF1KSD CTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEP
170 180 190 200 210 220
340 350 360 370 380 390
pF1KSD CGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDT
230 240 250 260 270 280
400 410 420 430 440 450
pF1KSD GNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNN
290 300 310 320 330 340
460 470 480 490 500 510
pF1KSD FCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKD
350 360 370 380 390 400
520 530 540 550 560 570
pF1KSD NSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQC
410 420 430 440 450 460
580 590 600 610 620 630
pF1KSD PCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKES
470 480 490 500 510 520
640 650 660 670 680 690
pF1KSD VQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSV
530 540 550 560 570 580
700 710 720 730 740
pF1KSD NPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL
590 600 610 620 630
>>XP_016879841 (OMIM: 601674) PREDICTED: histone-lysine (410 aa)
initn: 2879 init1: 2879 opt: 2879 Z-score: 2412.3 bits: 456.2 E(85289): 1.3e-127
Smith-Waterman score: 2879; 99.8% identity (99.8% similar) in 409 aa overlap (339-747:2-410)
310 320 330 340 350 360
pF1KSD LHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHIV
:: :::::::::::::::::::::::::::
XP_016 MLLKEGAKEYAMLHNPRSKCSGRRRRRHHIV
10 20 30
370 380 390 400 410 420
pF1KSD SASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAP
40 50 60 70 80 90
430 440 450 460 470 480
pF1KSD SEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMN
100 110 120 130 140 150
490 500 510 520 530 540
pF1KSD PSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFC
160 170 180 190 200 210
550 560 570 580 590 600
pF1KSD QCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQ
220 230 240 250 260 270
610 620 630 640 650 660
pF1KSD RGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLF
280 290 300 310 320 330
670 680 690 700 710 720
pF1KSD NLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYR
340 350 360 370 380 390
730 740
pF1KSD YSQADALKYVGIERETDVL
:::::::::::::::::::
XP_016 YSQADALKYVGIERETDVL
400 410
>>NP_001190176 (OMIM: 277590,601573) histone-lysine N-me (746 aa)
initn: 3051 init1: 1795 opt: 2701 Z-score: 2260.7 bits: 429.0 E(85289): 3.5e-119
Smith-Waterman score: 3353; 65.0% identity (82.3% similar) in 758 aa overlap (15-746:15-745)
10 20 30 40 50 60
pF1KSD MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
:...:::::::::::::.. .:... .: :. :.:.:::.::
NP_001 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
:. :.:::. . ::. ..:.. : . : .: . ...::.:: :::::::::::::
NP_001 KQRRIQPVHILTSVSSLRGTRECSVTSDLD-FPTQVIPLKTLNAVASVPIMYSWSPLQQN
70 80 90 100 110
130 140 150 160 170 180
pF1KSD FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
::::::::: ::::::::: ..: :::::::.::::::::..: : .:.: .:.:::
NP_001 FMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDREC--G--FINDEIFVELV
120 130 140 150 160 170
190 200 210 220 230
pF1KSD DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNK--KSSK--KQFPNDMI
.::.::.:.. : .:: :: .: :..:.. .: .. : :. ..::.: :
NP_001 NALGQYNDDD-----DDDDG--DDPEE-----REEKQKDLEDHRDDKESRPPRKFPSDKI
180 190 200 210 220
240 250 260 270 280 290
pF1KSD FSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHT
: ::.::::..:. ...::.:.::::.. :.::::.::::::::::::::::::::::::
NP_001 FEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHT
230 240 250 260 270 280
300 310 320 330 340 350
pF1KSD LFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAM------L
:::::::::::::::::::::.::::: : .. .::: .:. ::::::.: .
NP_001 LFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERI
290 300 310 320 330 340
360 370 380 390
pF1KSD HNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGN---------------D
..: .. .:::: : :. :. . . : :.:. ::::..:. :
NP_001 KTPPKRPGGRRRGRLPNNSSRPSTPTIN-VLESKDTDSDREAGTETGGENNDKEEEEKKD
350 360 370 380 390 400
400 410 420 430 440 450
pF1KSD WASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCS
.::::::::::::: :.: . :: : :::.::: :.:::. :::..:::.
NP_001 ETSSSSEANSRCQTPIKMKPNIEPP---------ENVEWSGAEASMFRVLIGTYYDNFCA
410 420 430 440 450
460 470 480 490 500 510
pF1KSD IARLLGTKTCKQVFQFAVKES-LILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNS
::::.:::::.::..: :::: .: :.... .: .:::::::::::::::::::::.:
NP_001 IARLIGTKTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGS
460 470 480 490 500 510
520 530 540 550 560 570
pF1KSD STQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPC
:..:::::::::: .::::.:::...::::::::::. .:::::::::::.:::::::::
NP_001 SNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPC
520 530 540 550 560 570
580 590 600 610 620 630
pF1KSD YLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQ
:::::::::::::::::..::: : ::::::::::: ::::::::::::::: :::. ::
NP_001 YLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQ
580 590 600 610 620 630
640 650 660 670 680 690
pF1KSD KNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNP
:::::::::::.::::::::::::::::: ::::::::::::::::::::::::::::::
NP_001 KNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNP
640 650 660 670 680 690
700 710 720 730 740
pF1KSD NCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL
::::::.:::::::::::::::::.:::::::::::::::::::::::: ..
NP_001 NCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP
700 710 720 730 740
747 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:35:29 2016 done: Thu Nov 3 01:35:31 2016
Total Scan time: 11.760 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]