Result of FASTA (omim) for
pF1KSDA0083
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0083, 1060 aa
1>>>pF1KSDA0083 1060 - 1060 aa - 1060 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7793+/-0.000568; mu= 19.4674+/- 0.035
mean_var=77.0506+/-15.440, 0's: 0 Z-trim(107.1): 57 B-trim: 0 in 0/49
Lambda= 0.146112
statistics sampled from 15075 (15129) to 15075 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.502), E-opt: 0.2 (0.177), width: 16
Scan time: 14.170
The best scores are: opt bits E(85289)
NP_001073918 (OMIM: 601810,615156,615807) DNA repl (1060) 6979 1482.0 0
XP_006717743 (OMIM: 601810,615156,615807) PREDICTE (1090) 6979 1482.0 0
XP_016871288 (OMIM: 601810,615156,615807) PREDICTE ( 836) 5498 1169.7 0
XP_011537719 (OMIM: 601810,615156,615807) PREDICTE ( 700) 4604 981.2 0
XP_005261980 (OMIM: 605794) PREDICTED: RNA helicas (1191) 380 91.0 4.5e-17
NP_061868 (OMIM: 605794) RNA helicase Mov10l1 isof (1211) 380 91.0 4.5e-17
NP_001157577 (OMIM: 605794) RNA helicase Mov10l1 i (1165) 372 89.3 1.4e-16
NP_001157578 (OMIM: 605794) RNA helicase Mov10l1 i ( 338) 310 75.9 4.3e-13
NP_002902 (OMIM: 601430) regulator of nonsense tra (1118) 299 73.9 5.8e-12
XP_016882595 (OMIM: 601430) PREDICTED: regulator o (1126) 299 73.9 5.9e-12
NP_001284478 (OMIM: 601430) regulator of nonsense (1129) 299 73.9 5.9e-12
XP_016882594 (OMIM: 601430) PREDICTED: regulator o (1137) 299 73.9 5.9e-12
NP_001157576 (OMIM: 605794) RNA helicase Mov10l1 i (1165) 296 73.3 9.4e-12
XP_011543296 (OMIM: 600502,604320,616155) PREDICTE ( 582) 262 65.9 7.5e-10
XP_005274032 (OMIM: 600502,604320,616155) PREDICTE ( 617) 262 65.9 7.9e-10
XP_005274031 (OMIM: 600502,604320,616155) PREDICTE ( 656) 262 66.0 8.3e-10
XP_016873158 (OMIM: 600502,604320,616155) PREDICTE ( 656) 262 66.0 8.3e-10
XP_016873159 (OMIM: 600502,604320,616155) PREDICTE ( 656) 262 66.0 8.3e-10
XP_016873160 (OMIM: 600502,604320,616155) PREDICTE ( 546) 259 65.3 1.1e-09
NP_002171 (OMIM: 600502,604320,616155) DNA-binding ( 993) 262 66.1 1.2e-09
XP_016884324 (OMIM: 605794) PREDICTED: RNA helicas ( 730) 242 61.8 1.7e-08
XP_011529005 (OMIM: 605794) PREDICTED: RNA helicas ( 730) 242 61.8 1.7e-08
XP_016884325 (OMIM: 605794) PREDICTED: RNA helicas ( 730) 242 61.8 1.7e-08
XP_011529004 (OMIM: 605794) PREDICTED: RNA helicas (1015) 242 61.8 2.2e-08
XP_011529003 (OMIM: 605794) PREDICTED: RNA helicas (1074) 242 61.9 2.3e-08
XP_011529002 (OMIM: 605794) PREDICTED: RNA helicas (1204) 242 61.9 2.6e-08
XP_011529001 (OMIM: 605794) PREDICTED: RNA helicas (1204) 242 61.9 2.6e-08
XP_011529000 (OMIM: 605794) PREDICTED: RNA helicas (1209) 242 61.9 2.6e-08
XP_016884322 (OMIM: 605794) PREDICTED: RNA helicas (1210) 242 61.9 2.6e-08
XP_011528999 (OMIM: 605794) PREDICTED: RNA helicas (1236) 242 61.9 2.6e-08
XP_011528998 (OMIM: 605794) PREDICTED: RNA helicas (1256) 242 61.9 2.7e-08
XP_016869985 (OMIM: 602433,606002,608465) PREDICTE ( 857) 235 60.3 5.4e-08
XP_005272228 (OMIM: 602433,606002,608465) PREDICTE (2706) 235 60.6 1.4e-07
XP_005272230 (OMIM: 602433,606002,608465) PREDICTE (2706) 235 60.6 1.4e-07
XP_011516706 (OMIM: 602433,606002,608465) PREDICTE (2706) 235 60.6 1.4e-07
XP_005272229 (OMIM: 602433,606002,608465) PREDICTE (2706) 235 60.6 1.4e-07
XP_011516707 (OMIM: 602433,606002,608465) PREDICTE (2706) 235 60.6 1.4e-07
XP_016869986 (OMIM: 602433,606002,608465) PREDICTE ( 828) 223 57.8 3e-07
XP_016869984 (OMIM: 602433,606002,608465) PREDICTE (2677) 223 58.1 8.1e-07
NP_055861 (OMIM: 602433,606002,608465) probable he (2677) 223 58.1 8.1e-07
XP_016880967 (OMIM: 606699) PREDICTED: probable he (1551) 207 54.6 5.3e-06
XP_006722279 (OMIM: 606699) PREDICTED: probable he (1578) 207 54.6 5.4e-06
XP_016880966 (OMIM: 606699) PREDICTED: probable he (1707) 207 54.6 5.7e-06
XP_006722278 (OMIM: 606699) PREDICTED: probable he (1735) 207 54.6 5.8e-06
NP_055692 (OMIM: 606699) probable helicase with zi (1942) 207 54.6 6.4e-06
NP_001317376 (OMIM: 606699) probable helicase with (1943) 207 54.6 6.4e-06
XP_005257945 (OMIM: 606699) PREDICTED: probable he (1969) 207 54.6 6.5e-06
XP_006722277 (OMIM: 606699) PREDICTED: probable he (1970) 207 54.6 6.5e-06
XP_011523846 (OMIM: 606699) PREDICTED: probable he (1970) 207 54.6 6.5e-06
NP_208384 (OMIM: 611265) helicase with zinc finger (2080) 198 52.7 2.5e-05
>>NP_001073918 (OMIM: 601810,615156,615807) DNA replicat (1060 aa)
initn: 6979 init1: 6979 opt: 6979 Z-score: 7946.1 bits: 1482.0 E(85289): 0
Smith-Waterman score: 6979; 100.0% identity (100.0% similar) in 1060 aa overlap (1-1060:1-1060)
10 20 30 40 50 60
pF1KSD MEQLNELELLMEKSFWEEAELPAELFQKKVVASFPRTVLSTGMDNRYLVLAVNTVQNKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEQLNELELLMEKSFWEEAELPAELFQKKVVASFPRTVLSTGMDNRYLVLAVNTVQNKEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NCEKRLVITASQSLENKELCILRNDWCSVPVEPGDIIHLEGDCTSDTWIIDKDFGYLILY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCEKRLVITASQSLENKELCILRNDWCSVPVEPGDIIHLEGDCTSDTWIIDKDFGYLILY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PDMLISGTSIASSIRCMRRAVLSETFRSSDPATRQMLIGTVLHEVFQKAINNSFAPEKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDMLISGTSIASSIRCMRRAVLSETFRSSDPATRQMLIGTVLHEVFQKAINNSFAPEKLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYLPSFCKWAGDFMHKNTSTDFPQMQLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYLPSFCKWAGDFMHKNTSTDFPQMQLSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PSDNSKDNSTCNIEVVKPMDIEESIWSPRFGLKGKIDVTVGVKIHRGYKTKYKIMPLELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSDNSKDNSTCNIEVVKPMDIEESIWSPRFGLKGKIDVTVGVKIHRGYKTKYKIMPLELK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD TGKESNSIEHRSQVVLYTLLSQERRADPEAGLLLYLKTGQMYPVPANHLDKRELLKLRNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGKESNSIEHRSQVVLYTLLSQERRADPEAGLLLYLKTGQMYPVPANHLDKRELLKLRNQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD MAFSLFHRISKSATRQKTQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQMDCSSVPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAFSLFHRISKSATRQKTQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQMDCSSVPI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD VMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NLIRMEHVKIVCDGQYLHNFQCKHGAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLIRMEHVKIVCDGQYLHNFQCKHGAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD TTVTCLLDRNLSVLPESTLFRLDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTVTCLLDRNLSVLPESTLFRLDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFRE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LVRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD RFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD TYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD PAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGM
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD VEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSL
970 980 990 1000 1010 1020
1030 1040 1050 1060
pF1KSD NCYPPLEKLLNHLNSEKLIIDLPSREHESLCHILGDFQRE
::::::::::::::::::::::::::::::::::::::::
NP_001 NCYPPLEKLLNHLNSEKLIIDLPSREHESLCHILGDFQRE
1030 1040 1050 1060
>>XP_006717743 (OMIM: 601810,615156,615807) PREDICTED: D (1090 aa)
initn: 6979 init1: 6979 opt: 6979 Z-score: 7946.0 bits: 1482.0 E(85289): 0
Smith-Waterman score: 6979; 100.0% identity (100.0% similar) in 1060 aa overlap (1-1060:31-1090)
10 20 30
pF1KSD MEQLNELELLMEKSFWEEAELPAELFQKKV
::::::::::::::::::::::::::::::
XP_006 MKTPCIPSPKQGSKGRGQSPAAQFAIPASRMEQLNELELLMEKSFWEEAELPAELFQKKV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD VASFPRTVLSTGMDNRYLVLAVNTVQNKEGNCEKRLVITASQSLENKELCILRNDWCSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VASFPRTVLSTGMDNRYLVLAVNTVQNKEGNCEKRLVITASQSLENKELCILRNDWCSVP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD VEPGDIIHLEGDCTSDTWIIDKDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEPGDIIHLEGDCTSDTWIIDKDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSD
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD PATRQMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PATRQMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD EDYLPSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKPMDIEESIWSPRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDYLPSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKPMDIEESIWSPRF
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD GLKGKIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLKGKIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD GLLLYLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLLLYLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEE
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD KTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD ESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVT
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD NLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCD
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD IDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQ
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD RQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLA
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD KFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPI
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLF
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD KRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLEL
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD EFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKA
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD GCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTV
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KSD GELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESL
1030 1040 1050 1060 1070 1080
1060
pF1KSD CHILGDFQRE
::::::::::
XP_006 CHILGDFQRE
1090
>>XP_016871288 (OMIM: 601810,615156,615807) PREDICTED: D (836 aa)
initn: 5498 init1: 5498 opt: 5498 Z-score: 6260.5 bits: 1169.7 E(85289): 0
Smith-Waterman score: 5498; 100.0% identity (100.0% similar) in 836 aa overlap (225-1060:1-836)
200 210 220 230 240 250
pF1KSD EMYRLNLSQDEIKQEVEDYLPSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIE
::::::::::::::::::::::::::::::
XP_016 MHKNTSTDFPQMQLSLPSDNSKDNSTCNIE
10 20 30
260 270 280 290 300 310
pF1KSD VVKPMDIEESIWSPRFGLKGKIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVKPMDIEESIWSPRFGLKGKIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQV
40 50 60 70 80 90
320 330 340 350 360 370
pF1KSD VLYTLLSQERRADPEAGLLLYLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLYTLLSQERRADPEAGLLLYLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSAT
100 110 120 130 140 150
380 390 400 410 420 430
pF1KSD RQKTQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQKTQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLK
160 170 180 190 200 210
440 450 460 470 480 490
pF1KSD QTHLEYFSLWCLMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTHLEYFSLWCLMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDG
220 230 240 250 260 270
500 510 520 530 540 550
pF1KSD QYLHNFQCKHGAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYLHNFQCKHGAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVL
280 290 300 310 320 330
560 570 580 590 600 610
pF1KSD PESTLFRLDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PESTLFRLDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHD
340 350 360 370 380 390
620 630 640 650 660 670
pF1KSD AKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLL
400 410 420 430 440 450
680 690 700 710 720 730
pF1KSD TSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYN
460 470 480 490 500 510
740 750 760 770 780 790
pF1KSD SQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPL
520 530 540 550 560 570
800 810 820 830 840 850
pF1KSD VLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVA
580 590 600 610 620 630
860 870 880 890 900 910
pF1KSD NAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNV
640 650 660 670 680 690
920 930 940 950 960 970
pF1KSD TEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDK
700 710 720 730 740 750
980 990 1000 1010 1020 1030
pF1KSD SIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLN
760 770 780 790 800 810
1040 1050 1060
pF1KSD SEKLIIDLPSREHESLCHILGDFQRE
::::::::::::::::::::::::::
XP_016 SEKLIIDLPSREHESLCHILGDFQRE
820 830
>>XP_011537719 (OMIM: 601810,615156,615807) PREDICTED: D (700 aa)
initn: 4604 init1: 4604 opt: 4604 Z-score: 5243.2 bits: 981.2 E(85289): 0
Smith-Waterman score: 4604; 100.0% identity (100.0% similar) in 700 aa overlap (361-1060:1-700)
340 350 360 370 380 390
pF1KSD GLLLYLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEE
::::::::::::::::::::::::::::::
XP_011 MAFSLFHRISKSATRQKTQLASLPQIIEEE
10 20 30
400 410 420 430 440 450
pF1KSD KTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTL
40 50 60 70 80 90
460 470 480 490 500 510
pF1KSD ESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVT
100 110 120 130 140 150
520 530 540 550 560 570
pF1KSD NLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCD
160 170 180 190 200 210
580 590 600 610 620 630
pF1KSD IDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQ
220 230 240 250 260 270
640 650 660 670 680 690
pF1KSD RQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLA
280 290 300 310 320 330
700 710 720 730 740 750
pF1KSD KFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPI
340 350 360 370 380 390
760 770 780 790 800 810
pF1KSD FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLF
400 410 420 430 440 450
820 830 840 850 860 870
pF1KSD KRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLEL
460 470 480 490 500 510
880 890 900 910 920 930
pF1KSD EFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKA
520 530 540 550 560 570
940 950 960 970 980 990
pF1KSD GCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTV
580 590 600 610 620 630
1000 1010 1020 1030 1040 1050
pF1KSD GELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESL
640 650 660 670 680 690
1060
pF1KSD CHILGDFQRE
::::::::::
XP_011 CHILGDFQRE
700
>>XP_005261980 (OMIM: 605794) PREDICTED: RNA helicase Mo (1191 aa)
initn: 269 init1: 90 opt: 380 Z-score: 427.6 bits: 91.0 E(85289): 4.5e-17
Smith-Waterman score: 409; 29.3% identity (57.6% similar) in 460 aa overlap (626-1043:725-1157)
600 610 620 630 640 650
pF1KSD IDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT----LIVGMPG
::. :. :.:..: : : .. : ::
XP_005 VLAPFTAEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRIL-SGDCRPLPYILFGPPG
700 710 720 730 740 750
660 670 680 690 700
pF1KSD TGKTTTICTLV-RILYACGFS-VLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAI
::::.:: : .. .: : .:. . ..::.: . :.: . :. :. . . .:. :
XP_005 TGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKV--LQPATMVRVN-AT
760 770 780 790 800 810
710 720 730 740 750 760
pF1KSD QQFTEQEICRSKSIKSLALLEELYNSQL--IVATTCM--GINHPIFSR-KIFDFCIVDEA
.: : : : . :...... :. ::: :. . : : : .::::
XP_005 CRFEEIVIDAVKPYCRDG--EDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEA
820 830 840 850 860
770 780 790 800 810
pF1KSD SQISQPICLGPLFF----SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRL------E
.: :.: :: :: . : ..::.:: .:: :.. .: : : :.. :...:: .
XP_005 GQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQ
870 880 890 900 910 920
820 830 840 850 860
pF1KSD QNKSA-----------VVQLTVQYRMNSKIMSLSNKLTYEGKLE-CGSDKVANAVINLRH
....: :..:. .:: . .. : ..: :. .:: :.. :...... ..
XP_005 RDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEK
930 940 950 960 970 980
870 880 890 900 910 920
pF1KSD FKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVF
. . : :.. ... . : ..: : .. : :: .
XP_005 LPKKGFPLIFHGVRGSE-----AREGKSPSWFNPAEAV----QVLR-----------YCC
990 1000 1010 1020
930 940 950 960 970 980
pF1KSD LTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGM--VEVNTVDKYQGRDKSIVLVS
: . ... : ::::.:.:::.:.. : :: :.. . ..:..:...::.. ....:
XP_005 LLAHSISSQVSASDIGVITPYRKQVEKIRILL-RNVDLMDIKVGSVEEFQGQEYLVIIIS
1030 1040 1050 1060 1070 1080
990 1000 1010 1020 1030
pF1KSD FVRSNKDGTVGE-----LLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNH--L
::::.: . .:.. .:.:::::: : ::.:: : : . ::..
XP_005 TVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSIT
1090 1100 1110 1120 1130 1140
1040 1050 1060
pF1KSD NSEKLIIDLPSREHESLCHILGDFQRE
:. . :::
XP_005 NGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS
1150 1160 1170 1180 1190
>>NP_061868 (OMIM: 605794) RNA helicase Mov10l1 isoform (1211 aa)
initn: 269 init1: 90 opt: 380 Z-score: 427.5 bits: 91.0 E(85289): 4.5e-17
Smith-Waterman score: 409; 29.3% identity (57.6% similar) in 460 aa overlap (626-1043:745-1177)
600 610 620 630 640 650
pF1KSD IDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT----LIVGMPG
::. :. :.:..: : : .. : ::
NP_061 VLAPFTAEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRIL-SGDCRPLPYILFGPPG
720 730 740 750 760 770
660 670 680 690 700
pF1KSD TGKTTTICTLV-RILYACGFS-VLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAI
::::.:: : .. .: : .:. . ..::.: . :.: . :. :. . . .:. :
NP_061 TGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKV--LQPATMVRVN-AT
780 790 800 810 820 830
710 720 730 740 750 760
pF1KSD QQFTEQEICRSKSIKSLALLEELYNSQL--IVATTCM--GINHPIFSR-KIFDFCIVDEA
.: : : : . :...... :. ::: :. . : : : .::::
NP_061 CRFEEIVIDAVKPYCRDG--EDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEA
840 850 860 870 880
770 780 790 800 810
pF1KSD SQISQPICLGPLFF----SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRL------E
.: :.: :: :: . : ..::.:: .:: :.. .: : : :.. :...:: .
NP_061 GQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQ
890 900 910 920 930 940
820 830 840 850 860
pF1KSD QNKSA-----------VVQLTVQYRMNSKIMSLSNKLTYEGKLE-CGSDKVANAVINLRH
....: :..:. .:: . .. : ..: :. .:: :.. :...... ..
NP_061 RDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEK
950 960 970 980 990 1000
870 880 890 900 910 920
pF1KSD FKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVF
. . : :.. ... . : ..: : .. : :: .
NP_061 LPKKGFPLIFHGVRGSE-----AREGKSPSWFNPAEAV----QVLR-----------YCC
1010 1020 1030 1040
930 940 950 960 970 980
pF1KSD LTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGM--VEVNTVDKYQGRDKSIVLVS
: . ... : ::::.:.:::.:.. : :: :.. . ..:..:...::.. ....:
NP_061 LLAHSISSQVSASDIGVITPYRKQVEKIRILL-RNVDLMDIKVGSVEEFQGQEYLVIIIS
1050 1060 1070 1080 1090 1100
990 1000 1010 1020 1030
pF1KSD FVRSNKDGTVGE-----LLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNH--L
::::.: . .:.. .:.:::::: : ::.:: : : . ::..
NP_061 TVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSIT
1110 1120 1130 1140 1150 1160
1040 1050 1060
pF1KSD NSEKLIIDLPSREHESLCHILGDFQRE
:. . :::
NP_061 NGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS
1170 1180 1190 1200 1210
>>NP_001157577 (OMIM: 605794) RNA helicase Mov10l1 isofo (1165 aa)
initn: 269 init1: 90 opt: 372 Z-score: 418.6 bits: 89.3 E(85289): 1.4e-16
Smith-Waterman score: 401; 29.5% identity (58.6% similar) in 430 aa overlap (626-1015:725-1127)
600 610 620 630 640 650
pF1KSD IDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT----LIVGMPG
::. :. :.:..: : : .. : ::
NP_001 VLAPFTAEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRIL-SGDCRPLPYILFGPPG
700 710 720 730 740 750
660 670 680 690 700
pF1KSD TGKTTTICTLV-RILYACGFS-VLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAI
::::.:: : .. .: : .:. . ..::.: . :.: . :. :. . . .:. :
NP_001 TGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKV--LQPATMVRVN-AT
760 770 780 790 800 810
710 720 730 740 750 760
pF1KSD QQFTEQEICRSKSIKSLALLEELYNSQL--IVATTCM--GINHPIFSR-KIFDFCIVDEA
.: : : : . :...... :. ::: :. . : : : .::::
NP_001 CRFEEIVIDAVKPYCRDG--EDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEA
820 830 840 850 860
770 780 790 800 810
pF1KSD SQISQPICLGPLFF----SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRL------E
.: :.: :: :: . : ..::.:: .:: :.. .: : : :.. :...:: .
NP_001 GQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQ
870 880 890 900 910 920
820 830 840 850 860
pF1KSD QNKSA-----------VVQLTVQYRMNSKIMSLSNKLTYEGKLE-CGSDKVANAVINLRH
....: :..:. .:: . .. : ..: :. .:: :.. :...... ..
NP_001 RDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEK
930 940 950 960 970 980
870 880 890 900 910 920
pF1KSD FKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVF
. . : :.. ... . : ..: : .. : :: .
NP_001 LPKKGFPLIFHGVRGSE-----AREGKSPSWFNPAEAV----QVLR-----------YCC
990 1000 1010 1020
930 940 950 960 970 980
pF1KSD LTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGM--VEVNTVDKYQGRDKSIVLVS
: . ... : ::::.:.:::.:.. : :: :.. . ..:..:...::.. ....:
NP_001 LLAHSISSQVSASDIGVITPYRKQVEKIRILL-RNVDLMDIKVGSVEEFQGQEYLVIIIS
1030 1040 1050 1060 1070 1080
990 1000 1010 1020 1030
pF1KSD FVRSNKDGTVGE-----LLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNS
::::.: . .:.. .:.:::::: : ::.::
NP_001 TVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRLWRGGGRPLLPSG
1090 1100 1110 1120 1130 1140
1040 1050 1060
pF1KSD EKLIIDLPSREHESLCHILGDFQRE
NP_001 ARIHRTREASGAQLICSG
1150 1160
>>NP_001157578 (OMIM: 605794) RNA helicase Mov10l1 isofo (338 aa)
initn: 296 init1: 90 opt: 310 Z-score: 356.1 bits: 75.9 E(85289): 4.3e-13
Smith-Waterman score: 324; 29.2% identity (58.3% similar) in 319 aa overlap (756-1043:7-304)
730 740 750 760 770 780
pF1KSD LALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFF----SRR
: .::::.: :.: :: :: . : .
NP_001 MFRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQ
10 20 30
790 800 810 820
pF1KSD FVLVGDHQQLPPLVLNREARALGMSESLFKRL------EQNKSA-----------VVQLT
.::.:: .:: :.. .: : : :.. :...:: .....: :..:.
NP_001 IVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLV
40 50 60 70 80 90
830 840 850 860 870 880
pF1KSD VQYRMNSKIMSLSNKLTYEGKLE-CGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLM
.:: . .. : ..: :. .:: :.. :...... ... . : :.. ...
NP_001 KNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSE----
100 110 120 130 140 150
890 900 910 920 930 940
pF1KSD GVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPY
. : ..: : .. : :: . : . ... : ::::.:.::
NP_001 -AREGKSPSWFNPAEAV----QVLR-----------YCCLLAHSISSQVSASDIGVITPY
160 170 180 190
950 960 970 980 990
pF1KSD RQQLKIINDLLARSIGM--VEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGE-----LLKD
:.:.. : :: :.. . ..:..:...::.. ....: ::::.: . .:..
NP_001 RKQVEKIRILL-RNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSN
200 210 220 230 240 250
1000 1010 1020 1030 1040 1050
pF1KSD WRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNH--LNSEKLIIDLPSREHESLCHIL
.:.:::::: : ::.:: : : . ::.. :. . :::
NP_001 SKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGE
260 270 280 290 300 310
1060
pF1KSD GDFQRE
NP_001 GVADPSYPVVPESTGPEKHQEPS
320 330
>>NP_002902 (OMIM: 601430) regulator of nonsense transcr (1118 aa)
initn: 505 init1: 182 opt: 299 Z-score: 335.7 bits: 73.9 E(85289): 5.8e-12
Smith-Waterman score: 616; 29.9% identity (59.5% similar) in 538 aa overlap (556-1050:416-910)
530 540 550 560 570 580
pF1KSD SLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLF-RLDQEEKNCDIDTPLGNLSKLMEN
.:: : :... :. .: ..: . .
NP_002 NYGDEIAIELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDET--SVSGYIYH
390 400 410 420 430 440
590 600 610 620 630 640
pF1KSD TFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT
.......:.:: . :. . .. :: ::. : :.: :: .. .
NP_002 KLLGHEVEDVIIKCQLPK--RFTAQGLPD------------LNHSQVYAVKTVL-QRPLS
450 460 470 480
650 660 670 680 690
pF1KSD LIVGMPGTGKTTTICTLVRILYACGFS-VLLTSYTHSAVDNILLKL-----------AKF
:: : ::::::.: :.: : : . ::. . .. :::.. :. ::
NP_002 LIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKS
490 500 510 520 530 540
700 710 720 730
pF1KSD K------IGFLRL-GQIQKVH--PAIQQFTEQ-----EIC-----RSKSIKSLALLEELY
. ..:: : .::... : .:.. . :. : ...: : : :.
NP_002 REAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLM
550 560 570 580 590 600
740 750 760 770 780 790
pF1KSD NSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFF-SRRFVLVGDHQQLP
:.. .. ::.: . : ... : ..::..: ..: :. :. . .....::::: ::
NP_002 NAD-VICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLG
610 620 630 640 650 660
800 810 820 830 840 850
pF1KSD PLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDK
:.:. ..: :.:.:::.:: ..: :::::. . .. ... :::.:. :
NP_002 PVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNG---
670 680 690 700 710 720
860 870 880 890 900 910
pF1KSD VANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVS
:. : :: ..: : .:..:. : :. . :.. ..:.:
NP_002 VTAA-------DRVKKGFDF-------QWP----QPDKPMFFYVTQ---GQEEIASSGTS
730 740 750 760
920 930 940 950 960
pF1KSD --NVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYR-------QQLKIINDLLARSIGMVEV
: ::: . .:. ..::: .:..::::.::. : ... ..: .. ::.
NP_002 YLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEI
770 780 790 800 810 820
970 980 990 1000 1010 1020
pF1KSD NTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCY
.:: .:::.:.....: ::.:. .: .:.: ::::::.:::.. .:..: .:.
NP_002 ASVDAFQGREKDFIILSCVRANEHQGIG-FLNDPRRLNVALTRARYGVIIVGNPKALSKQ
830 840 850 860 870 880
1030 1040 1050 1060
pF1KSD PPLEKLLNHLNSEKLIIDLP-SREHESLCHILGDFQRE
: ..:::. . .:.... : . .:::
NP_002 PLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAII
890 900 910 920 930 940
>>XP_016882595 (OMIM: 601430) PREDICTED: regulator of no (1126 aa)
initn: 505 init1: 182 opt: 299 Z-score: 335.7 bits: 73.9 E(85289): 5.9e-12
Smith-Waterman score: 616; 29.9% identity (59.5% similar) in 538 aa overlap (556-1050:424-918)
530 540 550 560 570 580
pF1KSD SLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLF-RLDQEEKNCDIDTPLGNLSKLMEN
.:: : :... :. .: ..: . .
XP_016 DYGDEIAIELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDET--SVSGYIYH
400 410 420 430 440 450
590 600 610 620 630 640
pF1KSD TFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT
.......:.:: . :. . .. :: ::. : :.: :: .. .
XP_016 KLLGHEVEDVIIKCQLPK--RFTAQGLPD------------LNHSQVYAVKTVL-QRPLS
460 470 480 490
650 660 670 680 690
pF1KSD LIVGMPGTGKTTTICTLVRILYACGFS-VLLTSYTHSAVDNILLKL-----------AKF
:: : ::::::.: :.: : : . ::. . .. :::.. :. ::
XP_016 LIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKS
500 510 520 530 540 550
700 710 720 730
pF1KSD K------IGFLRL-GQIQKVH--PAIQQFTEQ-----EIC-----RSKSIKSLALLEELY
. ..:: : .::... : .:.. . :. : ...: : : :.
XP_016 REAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLM
560 570 580 590 600 610
740 750 760 770 780 790
pF1KSD NSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFF-SRRFVLVGDHQQLP
:.. .. ::.: . : ... : ..::..: ..: :. :. . .....::::: ::
XP_016 NAD-VICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLG
620 630 640 650 660 670
800 810 820 830 840 850
pF1KSD PLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDK
:.:. ..: :.:.:::.:: ..: :::::. . .. ... :::.:. :
XP_016 PVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNG---
680 690 700 710 720 730
860 870 880 890 900 910
pF1KSD VANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVS
:. : :: ..: : .:..:. : :. . :.. ..:.:
XP_016 VTAA-------DRVKKGFDF-------QWP----QPDKPMFFYVTQ---GQEEIASSGTS
740 750 760 770
920 930 940 950 960
pF1KSD --NVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYR-------QQLKIINDLLARSIGMVEV
: ::: . .:. ..::: .:..::::.::. : ... ..: .. ::.
XP_016 YLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEI
780 790 800 810 820 830
970 980 990 1000 1010 1020
pF1KSD NTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCY
.:: .:::.:.....: ::.:. .: .:.: ::::::.:::.. .:..: .:.
XP_016 ASVDAFQGREKDFIILSCVRANEHQGIG-FLNDPRRLNVALTRARYGVIIVGNPKALSKQ
840 850 860 870 880 890
1030 1040 1050 1060
pF1KSD PPLEKLLNHLNSEKLIIDLP-SREHESLCHILGDFQRE
: ..:::. . .:.... : . .:::
XP_016 PLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAII
900 910 920 930 940 950
1060 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:51:33 2016 done: Wed Nov 2 23:51:35 2016
Total Scan time: 14.170 Total Display time: 0.290
Function used was FASTA [36.3.4 Apr, 2011]