Result of FASTA (omim) for
pF1KE9573
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9573, 474 aa
1>>>pF1KE9573 474 - 474 aa - 474 aa
Library: /omim/omim.rfq.tfa
64942286 residues in 91783 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6080+/-0.000402; mu= 15.8301+/- 0.025
mean_var=67.9529+/-14.298, 0's: 0 Z-trim(111.5): 308 B-trim: 876 in 1/48
Lambda= 0.155586
statistics sampled from 20615 (20935) to 20615 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.583), E-opt: 0.2 (0.228), width: 16
Scan time: 3.750
The best scores are: opt bits E(91783)
NP_001158210 (OMIM: 114131,166710) calcitonin rece ( 474) 3309 752.2 7.7e-217
NP_001733 (OMIM: 114131,166710) calcitonin recepto ( 474) 3309 752.2 7.7e-217
NP_001158209 (OMIM: 114131,166710) calcitonin rece ( 490) 2048 469.1 1.3e-131
NP_001258680 (OMIM: 114190) calcitonin gene-relate ( 461) 1872 429.6 9.4e-120
NP_005786 (OMIM: 114190) calcitonin gene-related p ( 461) 1872 429.6 9.4e-120
XP_005246291 (OMIM: 114190) calcitonin gene-relate ( 472) 1872 429.6 9.6e-120
XP_005246289 (OMIM: 114190) calcitonin gene-relate ( 472) 1872 429.6 9.6e-120
XP_005246288 (OMIM: 114190) calcitonin gene-relate ( 472) 1872 429.6 9.6e-120
XP_016858640 (OMIM: 114190) calcitonin gene-relate ( 472) 1872 429.6 9.6e-120
NP_001189404 (OMIM: 602034) corticotropin-releasin ( 438) 784 185.4 2.9e-46
NP_001874 (OMIM: 602034) corticotropin-releasing f ( 411) 772 182.7 1.8e-45
XP_024302433 (OMIM: 602034) corticotropin-releasin ( 411) 772 182.7 1.8e-45
NP_001189410 (OMIM: 602034) corticotropin-releasin ( 397) 771 182.5 2e-45
XP_016867241 (OMIM: 602034) corticotropin-releasin ( 397) 771 182.5 2e-45
XP_005265494 (OMIM: 192321) vasoactive intestinal ( 456) 770 182.3 2.7e-45
NP_001189411 (OMIM: 602034) corticotropin-releasin ( 410) 767 181.6 3.9e-45
NP_001238814 (OMIM: 192321) vasoactive intestinal ( 430) 766 181.4 4.8e-45
NP_004615 (OMIM: 192321) vasoactive intestinal pol ( 457) 766 181.4 5e-45
XP_005265495 (OMIM: 192321) vasoactive intestinal ( 416) 764 180.9 6.3e-45
NP_001238811 (OMIM: 192321) vasoactive intestinal ( 416) 764 180.9 6.3e-45
XP_011532381 (OMIM: 192321) vasoactive intestinal ( 416) 764 180.9 6.3e-45
NP_001238813 (OMIM: 192321) vasoactive intestinal ( 409) 757 179.3 1.9e-44
XP_005265496 (OMIM: 192321) vasoactive intestinal ( 410) 753 178.4 3.5e-44
NP_001189412 (OMIM: 602034) corticotropin-releasin ( 387) 748 177.3 7.2e-44
NP_001186566 (OMIM: 102981) pituitary adenylate cy ( 447) 745 176.6 1.3e-43
NP_004373 (OMIM: 122561) corticotropin-releasing f ( 415) 716 170.1 1.1e-41
NP_002971 (OMIM: 182098) secretin receptor precurs ( 440) 684 163.0 1.7e-39
XP_016860159 (OMIM: 182098) secretin receptor isof ( 435) 669 159.6 1.7e-38
XP_011509923 (OMIM: 182098) secretin receptor isof ( 445) 669 159.6 1.8e-38
XP_024308806 (OMIM: 182098) secretin receptor isof ( 372) 667 159.1 2.1e-38
NP_001138619 (OMIM: 122561) corticotropin-releasin ( 375) 652 155.7 2.1e-37
XP_016860161 (OMIM: 182098) secretin receptor isof ( 377) 652 155.7 2.1e-37
XP_005249675 (OMIM: 102981) pituitary adenylate cy ( 411) 645 154.2 6.9e-37
NP_001109 (OMIM: 102981) pituitary adenylate cycla ( 468) 645 154.2 7.7e-37
NP_001289949 (OMIM: 122561) corticotropin-releasin ( 314) 632 151.2 4.1e-36
NP_000155 (OMIM: 137241) gastric inhibitory polype ( 466) 629 150.6 9.3e-36
XP_016860160 (OMIM: 182098) secretin receptor isof ( 409) 608 145.9 2.2e-34
NP_000814 (OMIM: 139191,612781) growth hormone-rel ( 423) 606 145.4 3e-34
NP_001138620 (OMIM: 122561) corticotropin-releasin ( 401) 600 144.1 7.4e-34
NP_003373 (OMIM: 601970) vasoactive intestinal pol ( 438) 600 144.1 8e-34
XP_005249618 (OMIM: 601970) vasoactive intestinal ( 463) 600 144.1 8.4e-34
NP_001138618 (OMIM: 122561) corticotropin-releasin ( 444) 571 137.6 7.4e-32
XP_006716170 (OMIM: 601970) vasoactive intestinal ( 455) 570 137.4 8.8e-32
XP_005265401 (OMIM: 125350,156400,168468,215045,60 ( 562) 570 137.4 1.1e-31
XP_016862422 (OMIM: 125350,156400,168468,215045,60 ( 593) 570 137.4 1.1e-31
NP_000307 (OMIM: 125350,156400,168468,215045,60000 ( 593) 570 137.4 1.1e-31
NP_001171673 (OMIM: 125350,156400,168468,215045,60 ( 593) 570 137.4 1.1e-31
XP_011532270 (OMIM: 125350,156400,168468,215045,60 ( 600) 570 137.4 1.1e-31
XP_016862421 (OMIM: 125350,156400,168468,215045,60 ( 606) 570 137.4 1.1e-31
XP_011532269 (OMIM: 125350,156400,168468,215045,60 ( 606) 570 137.4 1.1e-31
>>NP_001158210 (OMIM: 114131,166710) calcitonin receptor (474 aa)
initn: 3309 init1: 3309 opt: 3309 Z-score: 4014.5 bits: 752.2 E(91783): 7.7e-217
Smith-Waterman score: 3309; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR
370 380 390 400 410 420
430 440 450 460 470
pF1KE9 PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
430 440 450 460 470
>>NP_001733 (OMIM: 114131,166710) calcitonin receptor is (474 aa)
initn: 3309 init1: 3309 opt: 3309 Z-score: 4014.5 bits: 752.2 E(91783): 7.7e-217
Smith-Waterman score: 3309; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR
370 380 390 400 410 420
430 440 450 460 470
pF1KE9 PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
430 440 450 460 470
>>NP_001158209 (OMIM: 114131,166710) calcitonin receptor (490 aa)
initn: 2048 init1: 2048 opt: 2048 Z-score: 2484.6 bits: 469.1 E(91783): 1.3e-131
Smith-Waterman score: 3267; 96.7% identity (96.7% similar) in 490 aa overlap (1-474:1-490)
10 20 30 40 50 60
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
70 80 90 100 110 120
130 140 150 160 170
pF1KE9 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFR------
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRKLTTIF
130 140 150 160 170 180
180 190 200 210 220
pF1KE9 ----------SLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHF
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLNWKYRKALSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 FHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVY
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 FNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKA
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE9 TMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKR
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE9 QWAQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QWAQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIP
430 440 450 460 470 480
470
pF1KE9 LNIIEQESSA
::::::::::
NP_001 LNIIEQESSA
490
>>NP_001258680 (OMIM: 114190) calcitonin gene-related pe (461 aa)
initn: 1851 init1: 1851 opt: 1872 Z-score: 2271.5 bits: 429.6 E(91783): 9.4e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:4-442)
10 20 30 40 50
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMDAQYKCYD
.: ::.: :: : . .: .: . : :.:.: :::.::.
NP_001 MEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQ
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 RMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGV
...: : :.:: ::::::::::::.:. ::. :.:.::::: :::::::::: ::. :
NP_001 KIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 WFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLG
::.:: .::::.:::.::. : ::.:.: :.::.:.::.::: .:.:::::: .:.::.
NP_001 WFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 CQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWM
:::.:::::.:.... ::.. ::::. :. : :: .:::::. .:.: :.:.::::::
NP_001 CQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 LCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHL
::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::.: .:::
NP_001 LCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 LYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFV
:::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::::::.::
NP_001 LYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 VFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRW
..:::: .:. ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:::... .
NP_001 LIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 GRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
. . ::: .... : . : .: :
NP_001 SNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
420 430 440 450 460
>>NP_005786 (OMIM: 114190) calcitonin gene-related pepti (461 aa)
initn: 1851 init1: 1851 opt: 1872 Z-score: 2271.5 bits: 429.6 E(91783): 9.4e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:4-442)
10 20 30 40 50
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMDAQYKCYD
.: ::.: :: : . .: .: . : :.:.: :::.::.
NP_005 MEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQ
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 RMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGV
...: : :.:: ::::::::::::.:. ::. :.:.::::: :::::::::: ::. :
NP_005 KIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 WFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLG
::.:: .::::.:::.::. : ::.:.: :.::.:.::.::: .:.:::::: .:.::.
NP_005 WFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 CQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWM
:::.:::::.:.... ::.. ::::. :. : :: .:::::. .:.: :.:.::::::
NP_005 CQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 LCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHL
::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::.: .:::
NP_005 LCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 LYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFV
:::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::::::.::
NP_005 LYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 VFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRW
..:::: .:. ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:::... .
NP_005 LIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 GRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
. . ::: .... : . : .: :
NP_005 SNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
420 430 440 450 460
>>XP_005246291 (OMIM: 114190) calcitonin gene-related pe (472 aa)
initn: 1851 init1: 1851 opt: 1872 Z-score: 2271.4 bits: 429.6 E(91783): 9.6e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:15-453)
10 20 30 40 50
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMD
.: ::.: :: : . .: .: . : :.:.:
XP_005 MLYSIFHFGLMMEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMT
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 AQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTK
:::.::....: : :.:: ::::::::::::.:. ::. :.:.::::: ::::::::::
XP_005 AQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 YCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIF
::. : ::.:: .::::.:::.::. : ::.:.: :.::.:.::.::: .:.::::::
XP_005 ICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 VFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMM
.:.::.:::.:::::.:.... ::.. ::::. :. : :: .:::::. .:.: :.:
XP_005 FYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW
.::::::::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::
XP_005 GCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 LSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP
.: .::::::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::
XP_005 ISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 LLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFK
::::.::..:::: .:. ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:
XP_005 LLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 IQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQ
::... .. . ::: .... : . : .: :
XP_005 IQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
420 430 440 450 460 470
pF1KE9 ESSA
>>XP_005246289 (OMIM: 114190) calcitonin gene-related pe (472 aa)
initn: 1851 init1: 1851 opt: 1872 Z-score: 2271.4 bits: 429.6 E(91783): 9.6e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:15-453)
10 20 30 40 50
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMD
.: ::.: :: : . .: .: . : :.:.:
XP_005 MLYSIFHFGLMMEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMT
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 AQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTK
:::.::....: : :.:: ::::::::::::.:. ::. :.:.::::: ::::::::::
XP_005 AQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 YCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIF
::. : ::.:: .::::.:::.::. : ::.:.: :.::.:.::.::: .:.::::::
XP_005 ICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 VFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMM
.:.::.:::.:::::.:.... ::.. ::::. :. : :: .:::::. .:.: :.:
XP_005 FYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW
.::::::::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::
XP_005 GCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 LSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP
.: .::::::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::
XP_005 ISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 LLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFK
::::.::..:::: .:. ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:
XP_005 LLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 IQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQ
::... .. . ::: .... : . : .: :
XP_005 IQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
420 430 440 450 460 470
pF1KE9 ESSA
>>XP_005246288 (OMIM: 114190) calcitonin gene-related pe (472 aa)
initn: 1851 init1: 1851 opt: 1872 Z-score: 2271.4 bits: 429.6 E(91783): 9.6e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:15-453)
10 20 30 40 50
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMD
.: ::.: :: : . .: .: . : :.:.:
XP_005 MLYSIFHFGLMMEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMT
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 AQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTK
:::.::....: : :.:: ::::::::::::.:. ::. :.:.::::: ::::::::::
XP_005 AQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 YCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIF
::. : ::.:: .::::.:::.::. : ::.:.: :.::.:.::.::: .:.::::::
XP_005 ICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 VFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMM
.:.::.:::.:::::.:.... ::.. ::::. :. : :: .:::::. .:.: :.:
XP_005 FYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW
.::::::::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::
XP_005 GCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 LSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP
.: .::::::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::
XP_005 ISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 LLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFK
::::.::..:::: .:. ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:
XP_005 LLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 IQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQ
::... .. . ::: .... : . : .: :
XP_005 IQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
420 430 440 450 460 470
pF1KE9 ESSA
>>XP_016858640 (OMIM: 114190) calcitonin gene-related pe (472 aa)
initn: 1851 init1: 1851 opt: 1872 Z-score: 2271.4 bits: 429.6 E(91783): 9.6e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:15-453)
10 20 30 40 50
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMD
.: ::.: :: : . .: .: . : :.:.:
XP_016 MLYSIFHFGLMMEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMT
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 AQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTK
:::.::....: : :.:: ::::::::::::.:. ::. :.:.::::: ::::::::::
XP_016 AQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 YCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIF
::. : ::.:: .::::.:::.::. : ::.:.: :.::.:.::.::: .:.::::::
XP_016 ICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 VFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMM
.:.::.:::.:::::.:.... ::.. ::::. :. : :: .:::::. .:.: :.:
XP_016 FYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW
.::::::::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::
XP_016 GCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 LSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP
.: .::::::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::
XP_016 ISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 LLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFK
::::.::..:::: .:. ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:
XP_016 LLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 IQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQ
::... .. . ::: .... : . : .: :
XP_016 IQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
420 430 440 450 460 470
pF1KE9 ESSA
>>NP_001189404 (OMIM: 602034) corticotropin-releasing fa (438 aa)
initn: 661 init1: 227 opt: 784 Z-score: 952.0 bits: 185.4 E(91783): 2.9e-46
Smith-Waterman score: 787; 33.0% identity (62.2% similar) in 436 aa overlap (36-452:25-437)
10 20 30 40 50
pF1KE9 TSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKM--------MDAQYKCYD
: :. :..:...: . :: :.
NP_001 MRGPSGPPGLLYVPHLLLCLLCLLPPPLQYAAGQSQMPKDQPLWALLEQY-CHT
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 RMQQLPAYQGEGPYCNRTWDGW-LCWDDTPAGVLSYQFCPDYFPD--FDPSEKVTKYCDE
: : .: ::: : : :: . ::.: . ::.:: .. .... . : :
NP_001 IMT-LTNLSGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 KGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIV----GHSLSIFTLVISLGIF
.:.: . ::..:. . .: .. . : .:.: :: .:. .:: .. .:
NP_001 NGTW-------ASKINYSQCEPILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLF
120 130 140 150 160
180 190 200 210 220
pF1KE9 VFFRSLGCQRVTLHKNMFLTYIL-NSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYM
. .::. : : ..: :.. :.:: : : ....::. :. . . : :. . . .:.
NP_001 LALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVD----HEVHESNEVWCRCITTIFNYF
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE9 MACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNC
.. :.:::. :: :::: ::.. ::. : . ..:: .:. . :: . : :..:
NP_001 VVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQC
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE9 WLSVETHLL--YIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMI
:.. : : :: .::.. .:..:: ::.::::.:.::.: . .:. .: ::::::..
NP_001 WFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLV
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE9 LVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIH-FQGFFVATIYCFCNNEVQTTVKRQW
:.::::: ...: :.. :..:. ..:... ::::::...::: :.::...:...:
NP_001 LLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRW
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE9 AQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLN
.:: . : : : : . .. : : . ... :
NP_001 --------HRWQDHHSLRVPMARAMSIPTS--PTRISFHSIKQTAAV
410 420 430
470
pF1KE9 IIEQESSA
474 residues in 1 query sequences
64942286 residues in 91783 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Sep 11 18:47:00 2018 done: Tue Sep 11 18:47:01 2018
Total Scan time: 3.750 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]