Result of FASTA (ccds) for
pF1KE3822
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3822, 2527 aa
1>>>pF1KE3822 2527 - 2527 aa - 2527 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.2322+/-0.00278; mu= -6.1470+/- 0.161
mean_var=823.3253+/-186.431, 0's: 0 Z-trim(101.8): 409 B-trim: 234 in 1/49
Lambda= 0.044698
statistics sampled from 6506 (6756) to 6506 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.512), E-opt: 0.2 (0.202), width: 16
Scan time: 3.880
The best scores are: opt bits E(33420)
CCDS31774.1 LRRK2 gene_id:120892|Hs109|chr12 (2527) 16617 1091.5 0
>>CCDS31774.1 LRRK2 gene_id:120892|Hs109|chr12 (2527 aa)
initn: 16617 init1: 16617 opt: 16617 Z-score: 5822.4 bits: 1091.5 E(33420): 0
Smith-Waterman score: 16617; 100.0% identity (100.0% similar) in 2527 aa overlap (1-2527:1-2527)
10 20 30 40 50 60
pF1KE3 MASGSCQGCEEDEETLKKLIVRLNNVQEGKQIETLVQILEDLLVFTYSEHASKLFQGKNI
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
CCDS31 MASGSCQGCEEDEETLKKLIVRLNNVQEGKQIETLVQILEDLLVFTYSERASKLFQGKNI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 HVPLLIVLDSYMRVASVQQVGWSLLCKLIEVCPGTMQSLMGPQDVGNDWEVLGVHQLILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 HVPLLIVLDSYMRVASVQQVGWSLLCKLIEVCPGTMQSLMGPQDVGNDWEVLGVHQLILK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 MLTVHNASVNLSVIGLKTLDLLLTSGKITLLILDEESDIFMLIFDAMHSFPANDEVQKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MLTVHNASVNLSVIGLKTLDLLLTSGKITLLILDEESDIFMLIFDAMHSFPANDEVQKLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 CKALHVLFERVSEEQLTEFVENKDYMILLSALTNFKDEEEIVLHVLHCLHSLAIPCNNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 CKALHVLFERVSEEQLTEFVENKDYMILLSALTNFKDEEEIVLHVLHCLHSLAIPCNNVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VLMSGNVRCYNIVVEAMKAFPMSERIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVKAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 VLMSGNVRCYNIVVEAMKAFPMSERIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVKAVQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QYPENAALQISALSCLALLTETIFLNQDLEEKNENQENDDEGEEDKLFWLEACYKALTWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 QYPENAALQISALSCLALLTETIFLNQDLEEKNENQENDDEGEEDKLFWLEACYKALTWH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 RKNKHVQEAACWALNNLLMYQNSLHEKIGDEDGHFPAHREVMLSMLMHSSSKEVFQASAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RKNKHVQEAACWALNNLLMYQNSLHEKIGDEDGHFPAHREVMLSMLMHSSSKEVFQASAN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 ALSTLLEQNVNFRKILLSKGIHLNVLELMQKHIHSPEVAESGCKMLNHLFEGSNTSLDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 ALSTLLEQNVNFRKILLSKGIHLNVLELMQKHIHSPEVAESGCKMLNHLFEGSNTSLDIM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 AAVVPKILTVMKRHETSLPVQLEALRAILHFIVPGMPEESREDTEFHHKLNMVKKQCFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 AAVVPKILTVMKRHETSLPVQLEALRAILHFIVPGMPEESREDTEFHHKLNMVKKQCFKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DIHKLVLAALNRFIGNPGIQKCGLKVISSIVHFPDALEMLSLEGAMDSVLHTLQMYPDDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DIHKLVLAALNRFIGNPGIQKCGLKVISSIVHFPDALEMLSLEGAMDSVLHTLQMYPDDQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 EIQCLGLSLIGYLITKKNVFIGTGHLLAKILVSSLYRFKDVAEIQTKGFQTILAILKLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EIQCLGLSLIGYLITKKNVFIGTGHLLAKILVSSLYRFKDVAEIQTKGFQTILAILKLSA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 SFSKLLVHHSFDLVIFHQMSSNIMEQKDQQFLNLCCKCFAKVAMDDYLKNVMLERACDQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SFSKLLVHHSFDLVIFHQMSSNIMEQKDQQFLNLCCKCFAKVAMDDYLKNVMLERACDQN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 NSIMVECLLLLGADANQAKEGSSLICQVCEKESSPKLVELLLNSGSREQDVRKALTISIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 NSIMVECLLLLGADANQAKEGSSLICQVCEKESSPKLVELLLNSGSREQDVRKALTISIG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 KGDSQIISLLLRRLALDVANNSICLGGFCIGKVEPSWLGPLFPDKTSNLRKQTNIASTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 KGDSQIISLLLRRLALDVANNSICLGGFCIGKVEPSWLGPLFPDKTSNLRKQTNIASTLA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 RMVIRYQMKSAVEEGTASGSDGNFSEDVLSKFDEWTFIPDSSMDSVFAQSDDLDSEGSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RMVIRYQMKSAVEEGTASGSDGNFSEDVLSKFDEWTFIPDSSMDSVFAQSDDLDSEGSEG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 SFLVKKKSNSISVGEFYRDAVLQRCSPNLQRHSNSLGPIFDHEDLLKRKRKILSSDDSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SFLVKKKSNSISVGEFYRDAVLQRCSPNLQRHSNSLGPIFDHEDLLKRKRKILSSDDSLR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 SSKLQSHMRHSDSISSLASEREYITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SSKLQSHMRHSDSISSLASEREYITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 NALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 NALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPLRLKELKILNLSKNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPLRLKELKILNLSKNH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 ISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIPEAILNLPHLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 ISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIPEAILNLPHLRS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 LDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEI
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 PPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELHLNFDFKHIGCKAKDIIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 PPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELHLNFDFKHIGCKAKDIIR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 FLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGMQSATVGIDVKDWPIQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 FLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGMQSATVGIDVKDWPIQI
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 RDKRKRDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RDKRKRDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 RASSSPVILVGTHLDVSDEKQRKACMSKITKELLNKRGFPAIRDYHFVNATEESDALAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RASSSPVILVGTHLDVSDEKQRKACMSKITKELLNKRGFPAIRDYHFVNATEESDALAKL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 RKTIINESLNFKIRDQLVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVREN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RKTIINESLNFKIRDQLVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVREN
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQILTVKVEGCPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 QLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQILTVKVEGCPK
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 HPKGIISRRDVEKFLSKKRKFPKNYMSQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 HPKGIISRRDVEKFLSKKRKFPKNYMSQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVI
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 ELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 ELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 NWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 NWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDI
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE3 CGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 CGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDLI
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE3 LADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQE
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE3 LVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVAD
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE3 GLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRA
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE3 PEVARGNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPNEFDELEIQGKLPDPVKEYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 PEVARGNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPNEFDELEIQGKLPDPVKEYG
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE3 CAPWPMVEKLIKQCLKENPQERPTSAQVFDILNSAELVCLTRRILLPKNVIVECMVATHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 CAPWPMVEKLIKQCLKENPQERPTSAQVFDILNSAELVCLTRRILLPKNVIVECMVATHH
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE3 NSRNASIWLGCGHTDRGQLSFLDLNTEGYTSEEVADSRILCLALVHLPVEKESWIVSGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 NSRNASIWLGCGHTDRGQLSFLDLNTEGYTSEEVADSRILCLALVHLPVEKESWIVSGTQ
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE3 SGTLLVINTEDGKKRHTLEKMTDSVTCLYCNSFSKQSKQKNFLLVGTADGKLAIFEDKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SGTLLVINTEDGKKRHTLEKMTDSVTCLYCNSFSKQSKQKNFLLVGTADGKLAIFEDKTV
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE3 KLKGAAPLKILNIGNVSTPLMCLSESTNSTERNVMWGGCGTKIFSFSNDFTIQKLIETRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 KLKGAAPLKILNIGNVSTPLMCLSESTNSTERNVMWGGCGTKIFSFSNDFTIQKLIETRT
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE3 SQLFSYAAFSDSNIITVVVDTALYIAKQNSPVVEVWDKKTEKLCGLIDCVHFLREVMVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SQLFSYAAFSDSNIITVVVDTALYIAKQNSPVVEVWDKKTEKLCGLIDCVHFLREVMVKE
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE3 NKESKHKMSYSGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRLIRVIYNFCNSVRVMMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 NKESKHKMSYSGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRLIRVIYNFCNSVRVMMT
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE3 AQLGSLKNVMLVLGYNRKNTEGTQKQKEIQSCLTVWDINLPHEVQNLEKHIEVRKELAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 AQLGSLKNVMLVLGYNRKNTEGTQKQKEIQSCLTVWDINLPHEVQNLEKHIEVRKELAEK
2470 2480 2490 2500 2510 2520
pF1KE3 MRRTSVE
:::::::
CCDS31 MRRTSVE
2527 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:51:18 2019 done: Thu Oct 24 21:51:19 2019
Total Scan time: 3.880 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]