Result of FASTA (omim) for
pF1KE3483
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3483, 1746 aa
1>>>pF1KE3483 1746 - 1746 aa - 1746 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.5827+/-0.000437; mu= -10.7201+/- 0.027
mean_var=360.7144+/-75.194, 0's: 0 Z-trim(121.2): 42 B-trim: 1843 in 1/59
Lambda= 0.067529
statistics sampled from 38801 (38848) to 38801 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.423), width: 16
Scan time: 10.870
The best scores are: opt bits E(91774)
XP_024305830 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_011520340 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_024305832 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
NP_079052 (OMIM: 614248) inactive tyrosine-protein (1746) 11672 1152.6 0
XP_024305825 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_005254732 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_024305829 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_005254728 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_011520336 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_011520337 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_011520335 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_024305831 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_024305826 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_024305824 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_024305827 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_005254727 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_024305828 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_005254730 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_011520338 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_011520339 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_005254731 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_011520341 (OMIM: 614248) inactive tyrosine-prot (1746) 11672 1152.6 0
XP_011520342 (OMIM: 614248) inactive tyrosine-prot (1366) 9036 895.8 0
XP_011520343 (OMIM: 614248) inactive tyrosine-prot (1046) 6929 690.4 2.4e-197
XP_011520344 (OMIM: 614248) inactive tyrosine-prot ( 710) 4738 476.9 3.1e-133
NP_001074295 (OMIM: 617344) inactive tyrosine-prot (1406) 1148 127.3 1.1e-27
NP_001356688 (OMIM: 617344) inactive tyrosine-prot (1406) 1148 127.3 1.1e-27
>>XP_024305830 (OMIM: 614248) inactive tyrosine-protein (1746 aa)
initn: 11672 init1: 11672 opt: 11672 Z-score: 6158.5 bits: 1152.6 E(91774): 0
Smith-Waterman score: 11672; 99.9% identity (100.0% similar) in 1746 aa overlap (1-1746:1-1746)
10 20 30 40 50 60
pF1KE3 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGKGCTSVTTAL
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_024 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
1690 1700 1710 1720 1730 1740
pF1KE3 KILQHR
::::::
XP_024 KILQHR
>>XP_011520340 (OMIM: 614248) inactive tyrosine-protein (1746 aa)
initn: 11672 init1: 11672 opt: 11672 Z-score: 6158.5 bits: 1152.6 E(91774): 0
Smith-Waterman score: 11672; 99.9% identity (100.0% similar) in 1746 aa overlap (1-1746:1-1746)
10 20 30 40 50 60
pF1KE3 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGKGCTSVTTAL
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_011 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
1690 1700 1710 1720 1730 1740
pF1KE3 KILQHR
::::::
XP_011 KILQHR
>>XP_024305832 (OMIM: 614248) inactive tyrosine-protein (1746 aa)
initn: 11672 init1: 11672 opt: 11672 Z-score: 6158.5 bits: 1152.6 E(91774): 0
Smith-Waterman score: 11672; 99.9% identity (100.0% similar) in 1746 aa overlap (1-1746:1-1746)
10 20 30 40 50 60
pF1KE3 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGKGCTSVTTAL
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_024 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
1690 1700 1710 1720 1730 1740
pF1KE3 KILQHR
::::::
XP_024 KILQHR
>>NP_079052 (OMIM: 614248) inactive tyrosine-protein kin (1746 aa)
initn: 11672 init1: 11672 opt: 11672 Z-score: 6158.5 bits: 1152.6 E(91774): 0
Smith-Waterman score: 11672; 99.9% identity (100.0% similar) in 1746 aa overlap (1-1746:1-1746)
10 20 30 40 50 60
pF1KE3 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGKGCTSVTTAL
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
NP_079 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
1690 1700 1710 1720 1730 1740
pF1KE3 KILQHR
::::::
NP_079 KILQHR
>>XP_024305825 (OMIM: 614248) inactive tyrosine-protein (1746 aa)
initn: 11672 init1: 11672 opt: 11672 Z-score: 6158.5 bits: 1152.6 E(91774): 0
Smith-Waterman score: 11672; 99.9% identity (100.0% similar) in 1746 aa overlap (1-1746:1-1746)
10 20 30 40 50 60
pF1KE3 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGKGCTSVTTAL
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_024 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
1690 1700 1710 1720 1730 1740
pF1KE3 KILQHR
::::::
XP_024 KILQHR
>>XP_005254732 (OMIM: 614248) inactive tyrosine-protein (1746 aa)
initn: 11672 init1: 11672 opt: 11672 Z-score: 6158.5 bits: 1152.6 E(91774): 0
Smith-Waterman score: 11672; 99.9% identity (100.0% similar) in 1746 aa overlap (1-1746:1-1746)
10 20 30 40 50 60
pF1KE3 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGKGCTSVTTAL
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_005 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
1690 1700 1710 1720 1730 1740
pF1KE3 KILQHR
::::::
XP_005 KILQHR
>>XP_024305829 (OMIM: 614248) inactive tyrosine-protein (1746 aa)
initn: 11672 init1: 11672 opt: 11672 Z-score: 6158.5 bits: 1152.6 E(91774): 0
Smith-Waterman score: 11672; 99.9% identity (100.0% similar) in 1746 aa overlap (1-1746:1-1746)
10 20 30 40 50 60
pF1KE3 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGKGCTSVTTAL
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_024 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
1690 1700 1710 1720 1730 1740
pF1KE3 KILQHR
::::::
XP_024 KILQHR
>>XP_005254728 (OMIM: 614248) inactive tyrosine-protein (1746 aa)
initn: 11672 init1: 11672 opt: 11672 Z-score: 6158.5 bits: 1152.6 E(91774): 0
Smith-Waterman score: 11672; 99.9% identity (100.0% similar) in 1746 aa overlap (1-1746:1-1746)
10 20 30 40 50 60
pF1KE3 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGKGCTSVTTAL
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_005 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
1690 1700 1710 1720 1730 1740
pF1KE3 KILQHR
::::::
XP_005 KILQHR
>>XP_011520336 (OMIM: 614248) inactive tyrosine-protein (1746 aa)
initn: 11672 init1: 11672 opt: 11672 Z-score: 6158.5 bits: 1152.6 E(91774): 0
Smith-Waterman score: 11672; 99.9% identity (100.0% similar) in 1746 aa overlap (1-1746:1-1746)
10 20 30 40 50 60
pF1KE3 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGKGCTSVTTAL
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_011 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
1690 1700 1710 1720 1730 1740
pF1KE3 KILQHR
::::::
XP_011 KILQHR
>>XP_011520337 (OMIM: 614248) inactive tyrosine-protein (1746 aa)
initn: 11672 init1: 11672 opt: 11672 Z-score: 6158.5 bits: 1152.6 E(91774): 0
Smith-Waterman score: 11672; 99.9% identity (100.0% similar) in 1746 aa overlap (1-1746:1-1746)
10 20 30 40 50 60
pF1KE3 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGKGCTSVTTAL
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_011 ENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIV
1690 1700 1710 1720 1730 1740
pF1KE3 KILQHR
::::::
XP_011 KILQHR
1746 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 15:54:40 2019 done: Tue Jul 16 15:54:42 2019
Total Scan time: 10.870 Total Display time: 0.710
Function used was FASTA [36.3.4 Apr, 2011]