Result of FASTA (ccds) for
pF1KE2600
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2600, 297 aa
1>>>pF1KE2600 297 - 297 aa - 297 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8183+/-0.000677; mu= 11.9256+/- 0.041
mean_var=150.3622+/-29.190, 0's: 0 Z-trim(116.9): 36 B-trim: 0 in 0/52
Lambda= 0.104594
statistics sampled from 17521 (17559) to 17521 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.833), E-opt: 0.2 (0.539), width: 16
Scan time: 2.800
The best scores are: opt bits E(32554)
CCDS34632.1 IGFBP3 gene_id:3486|Hs108|chr7 ( 297) 2097 326.9 1.1e-89
CCDS5505.1 IGFBP3 gene_id:3486|Hs108|chr7 ( 291) 2026 316.2 1.8e-86
CCDS42815.1 IGFBP2 gene_id:3485|Hs108|chr2 ( 325) 454 79.0 5.1e-15
CCDS11367.1 IGFBP4 gene_id:3487|Hs108|chr17 ( 258) 413 72.8 3.1e-13
CCDS2405.1 IGFBP5 gene_id:3488|Hs108|chr2 ( 272) 405 71.6 7.5e-13
>>CCDS34632.1 IGFBP3 gene_id:3486|Hs108|chr7 (297 aa)
initn: 2097 init1: 2097 opt: 2097 Z-score: 1723.6 bits: 326.9 E(32554): 1.1e-89
Smith-Waterman score: 2097; 99.7% identity (100.0% similar) in 297 aa overlap (1-297:1-297)
10 20 30 40 50 60
pF1KE2 MQRARPTLWAAALTLLVLLRGPPVARAGASSGGLGPVVRCEPCDARALAQCAPPPAVCAE
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
CCDS34 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG
190 200 210 220 230 240
250 260 270 280 290
pF1KE2 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
250 260 270 280 290
>>CCDS5505.1 IGFBP3 gene_id:3486|Hs108|chr7 (291 aa)
initn: 1130 init1: 1130 opt: 2026 Z-score: 1665.8 bits: 316.2 E(32554): 1.8e-86
Smith-Waterman score: 2026; 97.6% identity (98.0% similar) in 297 aa overlap (1-297:1-291)
10 20 30 40 50 60
pF1KE2 MQRARPTLWAAALTLLVLLRGPPVARAGASSGGLGPVVRCEPCDARALAQCAPPPAVCAE
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
CCDS55 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
:::::::::::: ::::::::::::::::::::::::::::::::::::::::::
CCDS55 SRLRAYLLPAPP------APGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
130 140 150 160 170
190 200 210 220 230 240
pF1KE2 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG
180 190 200 210 220 230
250 260 270 280 290
pF1KE2 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
240 250 260 270 280 290
>>CCDS42815.1 IGFBP2 gene_id:3485|Hs108|chr2 (325 aa)
initn: 537 init1: 303 opt: 454 Z-score: 383.2 bits: 79.0 E(32554): 5.1e-15
Smith-Waterman score: 526; 32.9% identity (57.1% similar) in 301 aa overlap (28-292:26-309)
10 20 30 40 50
pF1KE2 MQRARPTLWAAALTLLVLLRGPPVARAGASSGGLGP----VVRCEPCDARALAQCAPPPA
:::.:: : . :: :: . :: :.:::.
CCDS42 MLPRVGCPALPLPPPPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPV
10 20 30 40 50
60 70 80 90 100
pF1KE2 V---------------CAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEA
. ::::::::::::: .:: ::. ::.:: :::.:::: : :
CCDS42 APPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 RPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVS
:::::. :.: : . : : : .: ..... .:.: :.. :.
CCDS42 LPLQALVMGEGTCEK----RRDAEY--------GA--SPEQVADNGDDHSEGGLVENHVD
120 130 140 150 160
170 180 190 200 210
pF1KE2 STHRV----SDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETE--
:: . .. .::.: . . . : ..... . . .... : .. .
CCDS42 STMNMLGGGGSAGRKPLKSGMKELAVFREKVTEQHR---QMGKGGKHHLGLEEPKKLRPP
170 180 190 200 210 220
220 230 240 250 260
pF1KE2 --YGPCRREMEDTLNHLKFLNVLSPRG-------VHIPNCDKKGFYKKKQCRPSKGRKRG
::..:....:.... . . . :: .:::::::.:.:. :::. : . .::
CCDS42 PARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRG
230 240 250 260 270 280
270 280 290
pF1KE2 FCWCVD-KYGQPLPGYTT-KGKEDVHCYSMQSK
::::. . :. . : : .: . : .
CCDS42 ECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEARGVHTQRMQ
290 300 310 320
>>CCDS11367.1 IGFBP4 gene_id:3487|Hs108|chr17 (258 aa)
initn: 498 init1: 359 opt: 413 Z-score: 351.0 bits: 72.8 E(32554): 3.1e-13
Smith-Waterman score: 548; 35.0% identity (56.8% similar) in 280 aa overlap (16-290:10-250)
10 20 30 40 50 60
pF1KE2 MQRARPTLWAAALTLLVLLRGPPVARAGASSGGLGPVVRCEPCDARALAQCAPPPAVCAE
:.: :: : : : ...: ::. . ::.: :: . : :
CCDS11 MLPLCLVAALLLAAGP-----GPSLG--DEAIHCPPCSEEKLARCRPPVG-CEE
10 20 30 40
70 80 90 100 110 120
pF1KE2 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
:::::::::: ::::. :.:::.:: :::::::: : .::..:. :.:.:.. . .
CCDS11 LVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
.. : :. :. : . . : .:: : . .: .::
CCDS11 EAIQESLQPSDKDEGDHPNNSFSPCSAHDR--------------RCLQKHF----AKI--
110 120 130 140
190 200 210 220 230 240
pF1KE2 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG
. .. .. ..::. . :. : . : :. :.. .:..: . . .
CCDS11 --RDRSTSGGKMKVNGAPR---------EDARPVPQGSCQSELHRALERLAASQSRTHED
150 160 170 180 190
250 260 270 280 290
pF1KE2 VHI---PNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPG-YTTKGKEDVHCYSMQ
..: ::::..: .. :::.:. .:: ::::: : : ::: ::. : :
CCDS11 LYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADS
200 210 220 230 240 250
pF1KE2 SK
CCDS11 FRE
>>CCDS2405.1 IGFBP5 gene_id:3488|Hs108|chr2 (272 aa)
initn: 709 init1: 372 opt: 405 Z-score: 344.2 bits: 71.6 E(32554): 7.5e-13
Smith-Waterman score: 806; 44.1% identity (65.3% similar) in 297 aa overlap (8-296:3-268)
10 20 30 40 50 60
pF1KE2 MQRARPTLWAAALTLLVLLRGPPVARAGASSGGLGPVVRCEPCDARALAQCAPPPAVCAE
: .:.: ::. :: :.: :: :.::::: .::..: : : : :
CCDS24 MVLLTAVLLLLAAYAGP------AQS--LGSFVHCEPCDEKALSMCPPSPLGC-E
10 20 30 40
70 80 90 100 110 120
pF1KE2 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
::.:::::::.::::.::: ::.:::::..:::: : :: .::.::: :::.:.: .
CCDS24 LVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEK--
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
: . . : : ..:: :. . ::.. :.: :..:
CCDS24 SYREQVKIERDSREHEEP---TTSEMAEE-----TYSPKI----------FRPKHTRISE
110 120 130 140
190 200 210 220 230
pF1KE2 IKKGHAKDSQRYKVDYESQSTDTQNFSS-------ESKRETEYGPCRREMEDTLNHLKFL
.: .: ..: :. . ..: . : ..:.: :::::.:: .:..::
CCDS24 LKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKAS
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE2 NVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYT-TKGKEDVHCY
. ::.:..::::.:::::.:::.::.:::::.::::::::. :::. . : : .:.
CCDS24 PRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDG--DFQCH
210 220 230 240 250 260
pF1KE2 SMQSK
...:
CCDS24 TFDSSNVE
270
297 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:55:17 2016 done: Tue Nov 8 16:55:18 2016
Total Scan time: 2.800 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]