Result of FASTA (omim) for
pF1KE2575
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2575, 175 aa
1>>>pF1KE2575 175 - 175 aa - 175 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9734+/-0.000387; mu= 15.2771+/- 0.024
mean_var=81.1368+/-16.159, 0's: 0 Z-trim(113.7): 141 B-trim: 27 in 1/50
Lambda= 0.142385
statistics sampled from 22954 (23102) to 22954 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.271), width: 16
Scan time: 5.240
The best scores are: opt bits E(85289)
NP_067046 (OMIM: 613993) myosin regulatory light c ( 175) 1140 243.4 1.4e-64
XP_011513766 (OMIM: 613993) PREDICTED: myosin regu ( 208) 925 199.3 3.2e-51
XP_016867967 (OMIM: 613993) PREDICTED: myosin regu ( 132) 820 177.5 7.1e-45
XP_011513767 (OMIM: 613993) PREDICTED: myosin regu ( 163) 814 176.4 1.9e-44
XP_016863734 (OMIM: 160782) PREDICTED: myosin ligh ( 173) 736 160.4 1.3e-39
NP_002468 (OMIM: 160782) myosin light chain 5 [Hom ( 173) 736 160.4 1.3e-39
XP_016863735 (OMIM: 160782) PREDICTED: myosin ligh ( 173) 736 160.4 1.3e-39
XP_006713949 (OMIM: 160782) PREDICTED: myosin ligh ( 328) 729 159.2 5.8e-39
NP_000423 (OMIM: 160781,608758) myosin regulatory ( 166) 692 151.3 6.9e-37
XP_011513765 (OMIM: 613993) PREDICTED: myosin regu ( 231) 685 150.0 2.4e-36
XP_016867968 (OMIM: 613993) PREDICTED: myosin regu ( 99) 652 142.9 1.4e-34
XP_016863736 (OMIM: 160782) PREDICTED: myosin ligh ( 132) 582 128.6 3.7e-30
XP_016863737 (OMIM: 160782) PREDICTED: myosin ligh ( 132) 582 128.6 3.7e-30
XP_005249874 (OMIM: 613993) PREDICTED: myosin regu ( 155) 580 128.3 5.5e-30
NP_001138417 (OMIM: 609211) myosin regulatory ligh ( 172) 557 123.6 1.6e-28
NP_001138416 (OMIM: 609211) myosin regulatory ligh ( 172) 557 123.6 1.6e-28
NP_291024 (OMIM: 609211) myosin regulatory light c ( 172) 557 123.6 1.6e-28
NP_006088 (OMIM: 609905) myosin regulatory light p ( 172) 552 122.6 3.2e-28
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 296 69.9 2e-12
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 296 69.9 2e-12
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 296 69.9 2e-12
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 296 69.9 2e-12
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 296 69.9 2e-12
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 296 70.1 2.4e-12
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 281 66.9 1.7e-11
NP_852667 (OMIM: 609905) myosin regulatory light p ( 118) 224 55.1 4.7e-08
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 214 53.0 1.9e-07
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 214 53.0 1.9e-07
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 214 53.0 1.9e-07
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 214 53.0 1.9e-07
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 214 53.0 1.9e-07
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 214 53.0 1.9e-07
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 214 53.0 1.9e-07
NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens] ( 172) 209 52.1 5.2e-07
XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203) 203 51.0 1.4e-06
NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164) 199 50.1 2.1e-06
NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181) 199 50.1 2.2e-06
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] ( 172) 198 49.9 2.5e-06
NP_003271 (OMIM: 191040,611879,613243) troponin C, ( 161) 192 48.6 5.6e-06
NP_003270 (OMIM: 191039) troponin C, skeletal musc ( 160) 190 48.2 7.4e-06
NP_001186558 (OMIM: 609930) myosin light chain 6B ( 208) 187 47.7 1.4e-05
NP_002466 (OMIM: 609930) myosin light chain 6B [Ho ( 208) 187 47.7 1.4e-05
XP_011527333 (OMIM: 191039) PREDICTED: troponin C, ( 145) 184 46.9 1.6e-05
NP_524147 (OMIM: 609931) myosin light polypeptide ( 151) 181 46.3 2.6e-05
NP_062829 (OMIM: 607315) calcium-binding protein 5 ( 173) 174 44.9 7.6e-05
NP_057450 (OMIM: 607314,614899) calcium-binding pr ( 220) 174 45.0 9.1e-05
NP_066299 (OMIM: 609931) myosin light polypeptide ( 151) 172 44.5 9.2e-05
NP_001305425 (OMIM: 607314,614899) calcium-binding ( 226) 174 45.1 9.2e-05
XP_016882481 (OMIM: 607315) PREDICTED: calcium-bin ( 284) 174 45.2 0.00011
NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo ( 167) 168 43.7 0.00017
>>NP_067046 (OMIM: 613993) myosin regulatory light chain (175 aa)
initn: 1140 init1: 1140 opt: 1140 Z-score: 1280.3 bits: 243.4 E(85289): 1.4e-64
Smith-Waterman score: 1140; 100.0% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE2 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
130 140 150 160 170
>>XP_011513766 (OMIM: 613993) PREDICTED: myosin regulato (208 aa)
initn: 924 init1: 924 opt: 925 Z-score: 1040.7 bits: 199.3 E(85289): 3.2e-51
Smith-Waterman score: 1064; 84.1% identity (84.1% similar) in 208 aa overlap (1-175:1-208)
10 20 30 40 50 60
pF1KE2 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
70 80 90 100 110 120
130 140
pF1KE2 VVNKDEFKQLLLTQADKFSPAEV---------------------------------EQMF
::::::::::::::::::::::: ::::
XP_011 VVNKDEFKQLLLTQADKFSPAEVRLPSPFNTHPQHLLWAFTHDPEPSTSEAVAGRVEQMF
130 140 150 160 170 180
150 160 170
pF1KE2 ALTPMDLAGNIDYKSLCYIITHGDEKEE
::::::::::::::::::::::::::::
XP_011 ALTPMDLAGNIDYKSLCYIITHGDEKEE
190 200
>>XP_016867967 (OMIM: 613993) PREDICTED: myosin regulato (132 aa)
initn: 836 init1: 820 opt: 820 Z-score: 926.6 bits: 177.5 E(85289): 7.1e-45
Smith-Waterman score: 820; 97.7% identity (100.0% similar) in 129 aa overlap (1-129:1-129)
10 20 30 40 50 60
pF1KE2 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
::::::...
XP_016 VVNKDEWSRCSP
130
>>XP_011513767 (OMIM: 613993) PREDICTED: myosin regulato (163 aa)
initn: 830 init1: 814 opt: 814 Z-score: 918.8 bits: 176.4 E(85289): 1.9e-44
Smith-Waterman score: 814; 99.2% identity (100.0% similar) in 126 aa overlap (1-126:1-126)
10 20 30 40 50 60
pF1KE2 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
:::::.
XP_011 VVNKDDQPFPAPWEPPYPPSLCSHSPAVSCSDPPHPPGSSSFS
130 140 150 160
>>XP_016863734 (OMIM: 160782) PREDICTED: myosin light ch (173 aa)
initn: 730 init1: 714 opt: 736 Z-score: 831.9 bits: 160.4 E(85289): 1.3e-39
Smith-Waterman score: 736; 63.4% identity (89.7% similar) in 175 aa overlap (1-175:1-173)
10 20 30 40 50 60
pF1KE2 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
::::: :. : ... .:::.:::::: :::.:::::::::. .::::::.: : ::..:
XP_016 MASRK--TKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDT
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
:..:::..: ..::::::.:..::::::.::.::::::.::: ::.::.::.:.::.:::
XP_016 YASLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKG
60 70 80 90 100 110
130 140 150 160 170
pF1KE2 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
.::. .:.::..::::.. ::.::: .. .:.:::.:::.: :.::::.::::
XP_016 KINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
120 130 140 150 160 170
>>NP_002468 (OMIM: 160782) myosin light chain 5 [Homo sa (173 aa)
initn: 730 init1: 714 opt: 736 Z-score: 831.9 bits: 160.4 E(85289): 1.3e-39
Smith-Waterman score: 736; 63.4% identity (89.7% similar) in 175 aa overlap (1-175:1-173)
10 20 30 40 50 60
pF1KE2 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
::::: :. : ... .:::.:::::: :::.:::::::::. .::::::.: : ::..:
NP_002 MASRK--TKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDT
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
:..:::..: ..::::::.:..::::::.::.::::::.::: ::.::.::.:.::.:::
NP_002 YASLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKG
60 70 80 90 100 110
130 140 150 160 170
pF1KE2 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
.::. .:.::..::::.. ::.::: .. .:.:::.:::.: :.::::.::::
NP_002 KINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
120 130 140 150 160 170
>>XP_016863735 (OMIM: 160782) PREDICTED: myosin light ch (173 aa)
initn: 730 init1: 714 opt: 736 Z-score: 831.9 bits: 160.4 E(85289): 1.3e-39
Smith-Waterman score: 736; 63.4% identity (89.7% similar) in 175 aa overlap (1-175:1-173)
10 20 30 40 50 60
pF1KE2 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
::::: :. : ... .:::.:::::: :::.:::::::::. .::::::.: : ::..:
XP_016 MASRK--TKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDT
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
:..:::..: ..::::::.:..::::::.::.::::::.::: ::.::.::.:.::.:::
XP_016 YASLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKG
60 70 80 90 100 110
130 140 150 160 170
pF1KE2 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
.::. .:.::..::::.. ::.::: .. .:.:::.:::.: :.::::.::::
XP_016 KINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
120 130 140 150 160 170
>>XP_006713949 (OMIM: 160782) PREDICTED: myosin light ch (328 aa)
initn: 714 init1: 714 opt: 729 Z-score: 820.6 bits: 159.2 E(85289): 5.8e-39
Smith-Waterman score: 729; 63.2% identity (89.7% similar) in 174 aa overlap (2-175:157-328)
10 20 30
pF1KE2 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQ
:::: :. : ... .:::.:::::: :::
XP_006 PPSASWPCVHTPDCGPGRTLSSCAERRRPEASRK--TKKKEGGALRAQRASSNVFSNFEQ
130 140 150 160 170 180
40 50 60 70 80 90
pF1KE2 AQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQEGKGPINFTVFL
.:::::::::. .::::::.: : ::..::..:::..: ..::::::.:..::::::.::
XP_006 TQIQEFKEAFTLMDQNRDGFIDKEDLKDTYASLGKTNVKDDELDAMLKEASGPINFTMFL
190 200 210 220 230 240
100 110 120 130 140 150
pF1KE2 TLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFALTP
.::::::.::: ::.::.::.:.::.::: .::. .:.::..::::.. ::.::: ..
XP_006 NLFGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMSQADKMTAEEVDQMFQFAS
250 260 270 280 290 300
160 170
pF1KE2 MDLAGNIDYKSLCYIITHGDEKEE
.:.:::.:::.: :.::::.::::
XP_006 IDVAGNLDYKALSYVITHGEEKEE
310 320
>>NP_000423 (OMIM: 160781,608758) myosin regulatory ligh (166 aa)
initn: 716 init1: 680 opt: 692 Z-score: 783.2 bits: 151.3 E(85289): 6.9e-37
Smith-Waterman score: 692; 62.7% identity (87.0% similar) in 161 aa overlap (14-174:6-166)
10 20 30 40 50 60
pF1KE2 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
: :.: ..:::::::::.:::::::::. .::::::.: : :::.:
NP_000 MAPKKAKKRAGGANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDT
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
.. ::.:.: .::.: :..:. ::::::::::.:::::.:.::::.::.::..::: :::
NP_000 FAALGRVNVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKG
60 70 80 90 100 110
130 140 150 160 170
pF1KE2 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
:.. : ...: :::..:: ::.:::: : :..::.:::.: .:::::.::.
NP_000 VLKADYVREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD
120 130 140 150 160
>>XP_011513765 (OMIM: 613993) PREDICTED: myosin regulato (231 aa)
initn: 684 init1: 684 opt: 685 Z-score: 773.6 bits: 150.0 E(85289): 2.4e-36
Smith-Waterman score: 1008; 75.8% identity (75.8% similar) in 231 aa overlap (1-175:1-231)
10 20 30
pF1KE2 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKE---------------------
:::::::::::::::::::::::::::::::::::::::
XP_011 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEVSPPPPTFPRAGGCSHLKAPI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE2 --AFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEK
70 80 90 100 110 120
100 110 120 130 140
pF1KE2 LNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEV--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVRLPSPFNTHPQHLL
130 140 150 160 170 180
150 160 170
pF1KE2 -------------------EQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
::::::::::::::::::::::::::::::::
XP_011 WAFTHDPEPSTSEAVAGRVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
190 200 210 220 230
175 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:16:36 2016 done: Fri Nov 4 18:16:37 2016
Total Scan time: 5.240 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]