Result of FASTA (omim) for
pF1KE2461
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2461, 587 aa
1>>>pF1KE2461 587 - 587 aa - 587 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2203+/-0.00041; mu= 20.6042+/- 0.025
mean_var=96.6363+/-20.611, 0's: 0 Z-trim(113.3): 107 B-trim: 0 in 0/50
Lambda= 0.130468
statistics sampled from 22489 (22601) to 22489 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.265), width: 16
Scan time: 8.830
The best scores are: opt bits E(85289)
NP_803884 (OMIM: 606225) taste receptor type 1 mem ( 587) 4060 775.2 0
XP_016857892 (OMIM: 606225) PREDICTED: taste recep ( 589) 3611 690.7 3.6e-198
XP_011540505 (OMIM: 606225) PREDICTED: taste recep ( 763) 2929 562.4 1.9e-159
NP_619642 (OMIM: 606225) taste receptor type 1 mem ( 841) 2929 562.5 2e-159
XP_016857891 (OMIM: 606225) PREDICTED: taste recep ( 843) 2929 562.5 2e-159
NP_689418 (OMIM: 606226) taste receptor type 1 mem ( 839) 937 187.5 1.5e-46
XP_011540508 (OMIM: 606225) PREDICTED: taste recep ( 580) 820 165.3 4.9e-40
NP_001273283 (OMIM: 613572) G-protein coupled rece ( 751) 737 149.8 3e-35
XP_005247894 (OMIM: 145980,239200,601198,601199,61 ( 917) 736 149.7 3.9e-35
XP_016862813 (OMIM: 145980,239200,601198,601199,61 (1078) 736 149.8 4.3e-35
XP_006713852 (OMIM: 145980,239200,601198,601199,61 (1078) 736 149.8 4.3e-35
XP_016862814 (OMIM: 145980,239200,601198,601199,61 (1078) 736 149.8 4.3e-35
NP_000379 (OMIM: 145980,239200,601198,601199,61289 (1078) 736 149.8 4.3e-35
XP_016865964 (OMIM: 613572) PREDICTED: G-protein c ( 879) 727 148.0 1.2e-34
NP_683766 (OMIM: 613572) G-protein coupled recepto ( 926) 727 148.1 1.3e-34
NP_689414 (OMIM: 605865) taste receptor type 1 mem ( 852) 723 147.3 2e-34
NP_001273284 (OMIM: 613572) G-protein coupled rece ( 855) 703 143.5 2.7e-33
NP_001171536 (OMIM: 145980,239200,601198,601199,61 (1088) 676 138.5 1.1e-31
XP_016866277 (OMIM: 604473,614831) PREDICTED: meta ( 785) 576 119.6 4e-26
XP_016866275 (OMIM: 604473,614831) PREDICTED: meta ( 906) 576 119.6 4.4e-26
NP_001264994 (OMIM: 604473,614831) metabotropic gl ( 906) 576 119.6 4.4e-26
XP_016866274 (OMIM: 604473,614831) PREDICTED: meta ( 906) 576 119.6 4.4e-26
XP_016866276 (OMIM: 604473,614831) PREDICTED: meta ( 906) 576 119.6 4.4e-26
NP_001264995 (OMIM: 604473,614831) metabotropic gl ( 906) 576 119.6 4.4e-26
NP_001264996 (OMIM: 604473,614831) metabotropic gl ( 908) 576 119.6 4.5e-26
XP_016866272 (OMIM: 604473,614831) PREDICTED: meta (1194) 576 119.7 5.4e-26
XP_016866273 (OMIM: 604473,614831) PREDICTED: meta (1194) 576 119.7 5.4e-26
XP_011534084 (OMIM: 604473,614831) PREDICTED: meta (1194) 576 119.7 5.4e-26
NP_001264993 (OMIM: 604473,614831) metabotropic gl (1194) 576 119.7 5.4e-26
XP_016873116 (OMIM: 604102) PREDICTED: metabotropi (1180) 545 113.9 3e-24
NP_000833 (OMIM: 604102) metabotropic glutamate re (1180) 545 113.9 3e-24
XP_011541094 (OMIM: 604102) PREDICTED: metabotropi (1212) 545 113.9 3.1e-24
NP_001137303 (OMIM: 604102) metabotropic glutamate (1212) 545 113.9 3.1e-24
XP_006718891 (OMIM: 604102) PREDICTED: metabotropi (1212) 545 113.9 3.1e-24
NP_001269776 (OMIM: 604100) metabotropic glutamate ( 604) 539 112.5 4.2e-24
NP_001243741 (OMIM: 604100) metabotropic glutamate ( 743) 539 112.6 4.8e-24
NP_001243742 (OMIM: 604100) metabotropic glutamate ( 779) 539 112.6 5e-24
XP_016866282 (OMIM: 604100) PREDICTED: metabotropi ( 779) 539 112.6 5e-24
NP_001243738 (OMIM: 604100) metabotropic glutamate ( 796) 539 112.6 5.1e-24
XP_016866281 (OMIM: 604100) PREDICTED: metabotropi ( 832) 539 112.6 5.2e-24
NP_001243740 (OMIM: 604100) metabotropic glutamate ( 865) 539 112.6 5.4e-24
XP_016866280 (OMIM: 604100) PREDICTED: metabotropi ( 912) 539 112.7 5.6e-24
XP_016866279 (OMIM: 604100) PREDICTED: metabotropi ( 912) 539 112.7 5.6e-24
NP_000832 (OMIM: 604100) metabotropic glutamate re ( 912) 539 112.7 5.6e-24
XP_011531948 (OMIM: 604099) PREDICTED: metabotropi ( 494) 493 103.7 1.5e-21
XP_011531942 (OMIM: 604099) PREDICTED: metabotropi ( 678) 493 103.9 1.8e-21
XP_011531939 (OMIM: 604099) PREDICTED: metabotropi ( 678) 493 103.9 1.8e-21
XP_011531941 (OMIM: 604099) PREDICTED: metabotropi ( 678) 493 103.9 1.8e-21
XP_011531943 (OMIM: 604099) PREDICTED: metabotropi ( 678) 493 103.9 1.8e-21
XP_011531940 (OMIM: 604099) PREDICTED: metabotropi ( 678) 493 103.9 1.8e-21
>>NP_803884 (OMIM: 606225) taste receptor type 1 member (587 aa)
initn: 4060 init1: 4060 opt: 4060 Z-score: 4135.6 bits: 775.2 E(85289): 0
Smith-Waterman score: 4060; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KE2 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 DTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 SVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 RTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 RTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 GSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 QNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 QNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 NGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMM
490 500 510 520 530 540
550 560 570 580
pF1KE2 AGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST
:::::::::::::::::::::::::::::::::::::::::::::::
NP_803 AGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST
550 560 570 580
>>XP_016857892 (OMIM: 606225) PREDICTED: taste receptor (589 aa)
initn: 3605 init1: 3605 opt: 3611 Z-score: 3678.8 bits: 690.7 E(85289): 3.6e-198
Smith-Waterman score: 3611; 95.7% identity (96.6% similar) in 555 aa overlap (33-587:43-589)
10 20 30 40 50 60
pF1KE2 LCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLC
.: :. . ::: : . . ::
XP_016 LLLSLRALVEVVVWGTGPMTSKVPFAPKPQSLGGQRVSAGLCPSQLSLTGFLHR------
20 30 40 50 60
70 80 90 100 110 120
pF1KE2 DRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --SCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHKDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHKDT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 HGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLYNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLYNG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 LLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAG
490 500 510 520 530 540
550 560 570 580
pF1KE2 LSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST
550 560 570 580
>>XP_011540505 (OMIM: 606225) PREDICTED: taste receptor (763 aa)
initn: 3481 init1: 2929 opt: 2929 Z-score: 2983.7 bits: 562.4 E(85289): 1.9e-159
Smith-Waterman score: 2929; 100.0% identity (100.0% similar) in 421 aa overlap (167-587:343-763)
140 150 160 170 180 190
pF1KE2 SPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHKDTVAFNDNRDPLSSYN
::::::::::::::::::::::::::::::
XP_011 RAVYAVAHGLHQLLGCASGACSRGRVYPWQLLEQIHKVHFLLHKDTVAFNDNRDPLSSYN
320 330 340 350 360 370
200 210 220 230 240 250
pF1KE2 IIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT
380 390 400 410 420 430
260 270 280 290 300 310
pF1KE2 GFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHTSWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHTSWVL
440 450 460 470 480 490
320 330 340 350 360 370
pF1KE2 LAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPA
500 510 520 530 540 550
380 390 400 410 420 430
pF1KE2 CLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQ
560 570 580 590 600 610
440 450 460 470 480 490
pF1KE2 LLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGK
620 630 640 650 660 670
500 510 520 530 540 550
pF1KE2 DLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGLSSLSSGFGGYFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGLSSLSSGFGGYFLP
680 690 700 710 720 730
560 570 580
pF1KE2 KCYVILCRPDLNSTEHFQASIQDYTRRCGST
:::::::::::::::::::::::::::::::
XP_011 KCYVILCRPDLNSTEHFQASIQDYTRRCGST
740 750 760
>--
initn: 633 init1: 566 opt: 566 Z-score: 579.9 bits: 117.7 E(85289): 1.5e-25
Smith-Waterman score: 566; 98.9% identity (100.0% similar) in 89 aa overlap (79-167:1-89)
50 60 70 80 90 100
pF1KE2 GCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSD
::::::::::::::::::::::::::::::
XP_011 MRLGVEEINNSTALLPNITLGYQLYDVCSD
10 20 30
110 120 130 140 150 160
pF1KE2 SANVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 SANVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMIS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE2 EQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETK
XP_011 YAASSETLSVKRQYPSFLRTIPNDKYQVETMVLLLQKFGWTWISLVGSSDDYGQLGVQAL
100 110 120 130 140 150
>>NP_619642 (OMIM: 606225) taste receptor type 1 member (841 aa)
initn: 4048 init1: 2929 opt: 2929 Z-score: 2983.2 bits: 562.5 E(85289): 2e-159
Smith-Waterman score: 2929; 100.0% identity (100.0% similar) in 421 aa overlap (167-587:421-841)
140 150 160 170 180 190
pF1KE2 SPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHKDTVAFNDNRDPLSSYN
::::::::::::::::::::::::::::::
NP_619 RAVYAVAHGLHQLLGCASGACSRGRVYPWQLLEQIHKVHFLLHKDTVAFNDNRDPLSSYN
400 410 420 430 440 450
200 210 220 230 240 250
pF1KE2 IIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 IIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT
460 470 480 490 500 510
260 270 280 290 300 310
pF1KE2 GFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHTSWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 GFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHTSWVL
520 530 540 550 560 570
320 330 340 350 360 370
pF1KE2 LAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 LAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPA
580 590 600 610 620 630
380 390 400 410 420 430
pF1KE2 CLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 CLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQ
640 650 660 670 680 690
440 450 460 470 480 490
pF1KE2 LLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 LLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGK
700 710 720 730 740 750
500 510 520 530 540 550
pF1KE2 DLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGLSSLSSGFGGYFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 DLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGLSSLSSGFGGYFLP
760 770 780 790 800 810
560 570 580
pF1KE2 KCYVILCRPDLNSTEHFQASIQDYTRRCGST
:::::::::::::::::::::::::::::::
NP_619 KCYVILCRPDLNSTEHFQASIQDYTRRCGST
820 830 840
>--
initn: 1148 init1: 1133 opt: 1133 Z-score: 1156.2 bits: 224.4 E(85289): 1.2e-57
Smith-Waterman score: 1133; 99.4% identity (100.0% similar) in 167 aa overlap (1-167:1-167)
10 20 30 40 50 60
pF1KE2 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHK
::::::::::::::::::::::::::::::::::::::::::::::.
NP_619 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPK
NP_619 QYPSFLRTIPNDKYQVETMVLLLQKFGWTWISLVGSSDDYGQLGVQALENQATGQGICIA
190 200 210 220 230 240
>>XP_016857891 (OMIM: 606225) PREDICTED: taste receptor (843 aa)
initn: 3593 init1: 2929 opt: 2929 Z-score: 2983.2 bits: 562.5 E(85289): 2e-159
Smith-Waterman score: 2929; 100.0% identity (100.0% similar) in 421 aa overlap (167-587:423-843)
140 150 160 170 180 190
pF1KE2 SPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHKDTVAFNDNRDPLSSYN
::::::::::::::::::::::::::::::
XP_016 RAVYAVAHGLHQLLGCASGACSRGRVYPWQLLEQIHKVHFLLHKDTVAFNDNRDPLSSYN
400 410 420 430 440 450
200 210 220 230 240 250
pF1KE2 IIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT
460 470 480 490 500 510
260 270 280 290 300 310
pF1KE2 GFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHTSWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHTSWVL
520 530 540 550 560 570
320 330 340 350 360 370
pF1KE2 LAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPA
580 590 600 610 620 630
380 390 400 410 420 430
pF1KE2 CLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQ
640 650 660 670 680 690
440 450 460 470 480 490
pF1KE2 LLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGK
700 710 720 730 740 750
500 510 520 530 540 550
pF1KE2 DLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGLSSLSSGFGGYFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGLSSLSSGFGGYFLP
760 770 780 790 800 810
560 570 580
pF1KE2 KCYVILCRPDLNSTEHFQASIQDYTRRCGST
:::::::::::::::::::::::::::::::
XP_016 KCYVILCRPDLNSTEHFQASIQDYTRRCGST
820 830 840
>--
initn: 770 init1: 678 opt: 684 Z-score: 699.4 bits: 139.9 E(85289): 3.2e-32
Smith-Waterman score: 684; 81.5% identity (85.9% similar) in 135 aa overlap (33-167:43-169)
10 20 30 40 50 60
pF1KE2 LCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLC
.: :. . ::: : . . ::
XP_016 LLLSLRALVEVVVWGTGPMTSKVPFAPKPQSLGGQRVSAGLCPSQLSLTGFLHR------
20 30 40 50 60
70 80 90 100 110 120
pF1KE2 DRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --SCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHKDT
::::::::::::::::::::::::::::::::::::::::::::.
XP_016 GQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSV
XP_016 PSFLRTIPNDKYQVETMVLLLQKFGWTWISLVGSSDDYGQLGVQALENQATGQGICIAFK
190 200 210 220 230 240
>>NP_689418 (OMIM: 606226) taste receptor type 1 member (839 aa)
initn: 999 init1: 395 opt: 937 Z-score: 956.8 bits: 187.5 E(85289): 1.5e-46
Smith-Waterman score: 937; 33.1% identity (62.8% similar) in 489 aa overlap (101-583:361-837)
80 90 100 110 120
pF1KE2 HGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHHI-EL
: : : ... . : .: : :.. . .
NP_689 PIPGFSEFREWGPQAGPPPLSRTSQSYTCNQECDNCLNATLSFNT--ILRLSGERVVYSV
340 350 360 370 380
130 140 150 160 170 180
pF1KE2 QGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHKDTVAFNDNR
. . . .. ...: : ... : .. :. .:::.: ::.: : . :. .
NP_689 YSAVYAVAHALHSLLGCD---KSTCTKRVVYPW---QLLEEIWKVNFTLLDHQIFFDPQG
390 400 410 420 430 440
190 200 210 220 230 240
pF1KE2 DPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETK-IQWHGKDNQVPKSVCSSDCL
: .:. :.:. . : ..: . :.: .... . :.:: .: .: :.::. :
NP_689 DVALHLEIVQWQWDRSQNPFQSVAS--YYPLQRQLKNIQDISWHTINNTIPMSMCSKRCQ
450 460 470 480 490 500
250 260 270 280 290 300
pF1KE2 EGHQRVVTGFHHCCFECVPCGAGTFLNKS-DLYRCQPCGKEEWAPEGSQTCFPRTVVFLA
:... .:.: :::::. : :::::.. : :.:: : ..::. .. .:: : .:::
NP_689 SGQKKKPVGIHVCCFECIDCLPGTFLNHTEDEYECQACPNNEWSYQSETSCFKRQLVFLE
510 520 530 540 550 560
310 320 330 340 350 360
pF1KE2 LREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYG
.: . .. .: .: :. .: :..::.:::::: .::::: : .. .
NP_689 WHEAPTIAVALLAALGFLSTLAILVIFWRHFQTPIVRSAGGPMCFLMLTLLLVAYMVVPV
570 580 590 600 610 620
370 380 390 400 410 420
pF1KE2 FFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGL
. : : .:: ::::: : ::: .::..:::::.. ::.... : : ::. .: .
NP_689 YVGPPKVSTCLCRQALFPLCFTICISCIAVRSFQIVCAFKMASRFPRAYSYWVRYQGPYV
630 640 650 660 670 680
430 440 450 460 470 480
pF1KE2 FVMISSAAQLLICLTWLVVWTPLPA-REYQRFPHLVMLECTET--NSLGFILAFLYNGLL
. . .. ...: . ... :. : :..... :. . ::: : .. . ::
NP_689 SMAFITVLKMVIVVIGMLATGLSPTTRTDPDDPKITIVSCNPNYRNSLLFNTSL--DLLL
690 700 710 720 730
490 500 510 520 530 540
pF1KE2 SISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGLS
:. .:. .:.::.:: :::::: .:.:. : :.: ... : :.:.: . ..... .
NP_689 SVVGFSFAYMGKELPTNYNEAKFITLSMTFYFTSSVSLCTFMSAYSGVLVTIVDLLVTVL
740 750 760 770 780 790
550 560 570 580
pF1KE2 SLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST
.: . ::: ::::.:: :. :. .:.. :: :: :
NP_689 NLLAISLGYFGPKCYMILFYPERNTPAYFNSMIQGYTMRRD
800 810 820 830
>--
initn: 225 init1: 178 opt: 366 Z-score: 376.0 bits: 80.1 E(85289): 3.3e-14
Smith-Waterman score: 366; 36.7% identity (63.3% similar) in 207 aa overlap (19-217:16-215)
10 20 30 40 50
pF1KE2 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRP--E
:..: . .:.: :: :::::::.::: ::.. . : .
NP_689 MGPRAKTISSLFFLLWVLA-EPAENS-DFYLPGDYLLGGLFSLHANMKGIVHLNFLQ
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 VTLCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRV
: .: . . ::.:.::::..::::::...:::.. :::.. ::: : :: .:
NP_689 VPMC-KEYEVKVIGYNLMQAMRFAVEEINNDSSLLPGVLLGYEIVDVCYISNNVQPVLYF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 LSLPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLL------EQIH
:. .. . .: : .: :.::::::... . :.: .:: ::.:.. :
NP_689 LAHE-DNLLPIQEDYSNYISRVVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRD
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 KVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWH
::.: :. :.. .. . :: : .....:.:.
NP_689 KVRFPALLRTTPSADHHIEAMVQLMLHFRWN---WIIVLVSSDTYGRDNGQLLGERVARR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 GKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAP
NP_689 DICIAFQETLPTLQPNQNMTSEERQRLVTIVDKLQQSTARVVVVFSPDLTLYHFFNEVLR
240 250 260 270 280 290
>>XP_011540508 (OMIM: 606225) PREDICTED: taste receptor (580 aa)
initn: 1503 init1: 814 opt: 820 Z-score: 839.8 bits: 165.3 E(85289): 4.9e-40
Smith-Waterman score: 820; 86.5% identity (90.2% similar) in 133 aa overlap (167-298:423-554)
140 150 160 170 180 190
pF1KE2 SPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHKDTVAFNDNRDPLSSYN
::::::::::::::::::::::::::::::
XP_011 RAVYAVAHGLHQLLGCASGACSRGRVYPWQLLEQIHKVHFLLHKDTVAFNDNRDPLSSYN
400 410 420 430 440 450
200 210 220 230 240 250
pF1KE2 IIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT
460 470 480 490 500 510
260 270 280 290 300 310
pF1KE2 GFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQT-CFPRTVVFLALREHTSWV
::::::::::::::::::::: . . : . :. : . :
XP_011 GFHHCCFECVPCGAGTFLNKSATW-VRTCQRTTTRPNVSPSACSSTSCPGSPSSPRPAST
520 530 540 550 560 570
320 330 340 350 360 370
pF1KE2 LLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRP
XP_011 TASTCLRPT
580
>--
initn: 770 init1: 678 opt: 684 Z-score: 701.4 bits: 139.7 E(85289): 2.5e-32
Smith-Waterman score: 684; 81.5% identity (85.9% similar) in 135 aa overlap (33-167:43-169)
10 20 30 40 50 60
pF1KE2 LCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLC
.: :. . ::: : . . ::
XP_011 LLLSLRALVEVVVWGTGPMTSKVPFAPKPQSLGGQRVSAGLCPSQLSLTGFLHR------
20 30 40 50 60
70 80 90 100 110 120
pF1KE2 DRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 --SCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHKDT
::::::::::::::::::::::::::::::::::::::::::::.
XP_011 GQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSV
XP_011 PSFLRTIPNDKYQVETMVLLLQKFGWTWISLVGSSDDYGQLGVQALENQATGQGICIAFK
190 200 210 220 230 240
>>NP_001273283 (OMIM: 613572) G-protein coupled receptor (751 aa)
initn: 609 init1: 216 opt: 737 Z-score: 753.9 bits: 149.8 E(85289): 3e-35
Smith-Waterman score: 737; 29.4% identity (61.8% similar) in 453 aa overlap (140-587:244-688)
110 120 130 140 150 160
pF1KE2 ANVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLE
:: .. :.: .. . .: . .: .::
NP_001 ITTDDDYGRLALNTFIIQAEANNVCIAFKEVLPAFLSDNTIEVRINRTLKKIILEAQLLG
220 230 240 250 260 270
170 180 190 200 210 220
pF1KE2 QIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKI
...: : .. :. . : ..:... : . . : : .. . . : . .
NP_001 VLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWKEINGHMTVTKMAEYDLQNDVFIIPDQET
280 290 300 310 320 330
230 240 250 260 270 280
pF1KE2 QWHGKDNQVPKSVCSSDCLEGHQRVVTGFHH-CCFECVPCGAGTFLNKSDLYRCQPCG-K
. . .. . .: ::..: :... .: .: ::.:: : . . :..:. .: :. :
NP_001 KNEFRNLKQIQSKCSKECSPGQMKKTTRSQHICCYECQNCPENHYTNQTDMPHCLLCNNK
340 350 360 370 380 390
290 300 310 320 330 340
pF1KE2 EEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAG
.::: : :: . : .: . . .:: . : ....: .. .:. .:.::::.:.:
NP_001 THWAPVRSTMCFEKEVEYLNWNDSLAILLLILSLLGIIFVLVVGIIFTRNLNTPVVKSSG
400 410 420 430 440 450
350 360 370 380 390 400
pF1KE2 G-RLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIF
: :.:...: . .: :.::: .: ::..:...::. .::. ..:..... :
NP_001 GLRVCYVILLCHFLNFASTSFFIGEPQDFTCKTRQTMFGVSFTLCISCILTKSLKILLAF
460 470 480 490 500 510
410 420 430 440 450 460
pF1KE2 KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLEC
.:. :. : . . :... .. :..:: ::. .: . . .:....:::
NP_001 SFDPKLQKFLKCLYR---PILIIFTCTGIQVVICTLWLIFAAPTVEVNVS-LPRVIILEC
520 530 540 550 560
470 480 490 500 510 520
pF1KE2 TETNSLGFILAF-LYNGLLSISAFACSYLG-KDLPENYNEAKCVTFSLLFNFVSWIAFFT
: : :::: . : ..: :: : .. : ::::::: .::..:. :..::.:.
NP_001 EE----GSILAFGTMLGYIAILAFICFIFAFKGKYENYNEAKFITFGMLIYFIAWITFIP
570 580 590 600 610 620
530 540 550 560 570 580
pF1KE2 TASVYDGKYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRC
.. :::.::..... : : . . :.::::::.:. ..:. : : .:. .
NP_001 IYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICKQEINTKSAFLKMIYSYSSHS
630 640 650 660 670 680
pF1KE2 GST
:.
NP_001 VSSIALSPASLDSMSGNVTMTNPSSSGKSATWQKSKDLQAQAFAHICRENATSVSKTLPR
690 700 710 720 730 740
>--
initn: 124 init1: 96 opt: 228 Z-score: 236.2 bits: 54.0 E(85289): 2e-06
Smith-Waterman score: 228; 32.7% identity (60.7% similar) in 168 aa overlap (11-167:4-167)
10 20 30 40 50
pF1KE2 MLLCTARLVGLQLLISC-CWAFACHSTESSPD-F---TLPGDYLLAGLFPLHSGCLQVR-
: .::.: .: . ..:: : : :: ...::: .: :. .
NP_001 MAFLIILITCFVIILATSQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSED
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 --HRPEVTLCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSD-SAN
.::.. : .:. . :: ..: ::::: :::.. :::..::.:.. ..
NP_001 SPRRPQIQEC---VGFEISVFLQTLAMIHSIEMINNST-LLPGVKLGYEIYDTCTEVTVA
60 70 80 90 100
120 130 140 150 160
pF1KE2 VYATLRVLSLPG--QHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLE
. :::: :: . .. .:.. : : : : :::: .. . ... .:. :.:..
NP_001 MAATLRFLSKFNCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGY
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE2 QIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKI
NP_001 ESTAEILSDKIRFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFI
170 180 190 200 210 220
>>XP_005247894 (OMIM: 145980,239200,601198,601199,612899 (917 aa)
initn: 590 init1: 314 opt: 736 Z-score: 751.9 bits: 149.7 E(85289): 3.9e-35
Smith-Waterman score: 736; 31.4% identity (62.9% similar) in 423 aa overlap (167-576:299-714)
140 150 160 170 180 190
pF1KE2 SPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHK-DTVAFNDNRDPLSSY
.:.......: . . :.:.. : ...:
XP_005 ALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGDLVGNY
270 280 290 300 310 320
200 210 220 230 240
pF1KE2 NIIAWDWNGPKWTFTVLGSSTWSPV------QLNINETKIQWHGKDNQVPKSVCSSDCLE
.:: : . :. :. . : .: ::: :: : : . .:: : :: :::
XP_005 SIINWHLS-PEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGFSREVPFSNCSRDCLA
330 340 350 360 370 380
250 260 270 280 290 300
pF1KE2 GHQR-VVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLAL
: .. .. : :::::: : : . ...: :. : . :. :. .:. . . ::.
XP_005 GTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKCPDDFWSNENHTSCIAKEIEFLSW
390 400 410 420 430 440
310 320 330 340 350 360
pF1KE2 REHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAG-SGSLYG
: . .: .: ..: . :.: .::.:.... .: .:.: :: :.::.
XP_005 TEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRELSYLLLFSLLCCFSSSLF-
450 460 470 480 490 500
370 380 390 400 410 420
pF1KE2 FFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYH-AWVQNHGAG
:.::: .: ::: :...:.. .::. :.. .....:. .:.:: .: : .
XP_005 FIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVFE--AKIPTSFHRKWWGLNLQF
510 520 530 540 550 560
430 440 450 460 470 480
pF1KE2 LFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETN--SLGFILAFLYNGLL
:.:.. . :..::. :: . : :. . ..... : : . .:::... :. ::
XP_005 LLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFITCHEGSLMALGFLIG--YTCLL
570 580 590 600 610 620
490 500 510 520 530 540
pF1KE2 SISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTT-ASVYDGKYLPAANMMAGL
. : .. .. ::::.:::: .:::.:. :. ::.:. . ::.: ::.. :....: :
XP_005 AAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAYASTY-GKFVSAVEVIAIL
630 640 650 660 670 680
550 560 570 580
pF1KE2 SSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST
.. . .. :. : :.:: .:. :. :. . :
XP_005 AASFGLLACIFFNKIYIILFKPSRNTIEEVRCSTAAHAFKVAARATLRRSNVSRKRSSSL
690 700 710 720 730 740
XP_005 GGSTGSTPSSSISSKSNSEDPFPQPERQKQQQPLALTQQEQQQQPLTLPQQQRSQQQPRC
750 760 770 780 790 800
>>XP_016862813 (OMIM: 145980,239200,601198,601199,612899 (1078 aa)
initn: 803 init1: 314 opt: 736 Z-score: 751.0 bits: 149.8 E(85289): 4.3e-35
Smith-Waterman score: 736; 31.4% identity (62.9% similar) in 423 aa overlap (167-576:460-875)
140 150 160 170 180 190
pF1KE2 SPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHK-DTVAFNDNRDPLSSY
.:.......: . . :.:.. : ...:
XP_016 ALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGDLVGNY
430 440 450 460 470 480
200 210 220 230 240
pF1KE2 NIIAWDWNGPKWTFTVLGSSTWSPV------QLNINETKIQWHGKDNQVPKSVCSSDCLE
.:: : . :. :. . : .: ::: :: : : . .:: : :: :::
XP_016 SIINWHLS-PEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGFSREVPFSNCSRDCLA
490 500 510 520 530 540
250 260 270 280 290 300
pF1KE2 GHQR-VVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLAL
: .. .. : :::::: : : . ...: :. : . :. :. .:. . . ::.
XP_016 GTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKCPDDFWSNENHTSCIAKEIEFLSW
550 560 570 580 590 600
310 320 330 340 350 360
pF1KE2 REHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAG-SGSLYG
: . .: .: ..: . :.: .::.:.... .: .:.: :: :.::.
XP_016 TEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRELSYLLLFSLLCCFSSSLF-
610 620 630 640 650 660
370 380 390 400 410 420
pF1KE2 FFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYH-AWVQNHGAG
:.::: .: ::: :...:.. .::. :.. .....:. .:.:: .: : .
XP_016 FIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVFE--AKIPTSFHRKWWGLNLQF
670 680 690 700 710 720
430 440 450 460 470 480
pF1KE2 LFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETN--SLGFILAFLYNGLL
:.:.. . :..::. :: . : :. . ..... : : . .:::... :. ::
XP_016 LLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFITCHEGSLMALGFLIG--YTCLL
730 740 750 760 770 780
490 500 510 520 530 540
pF1KE2 SISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTT-ASVYDGKYLPAANMMAGL
. : .. .. ::::.:::: .:::.:. :. ::.:. . ::.: ::.. :....: :
XP_016 AAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAYASTY-GKFVSAVEVIAIL
790 800 810 820 830 840
550 560 570 580
pF1KE2 SSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST
.. . .. :. : :.:: .:. :. :. . :
XP_016 AASFGLLACIFFNKIYIILFKPSRNTIEEVRCSTAAHAFKVAARATLRRSNVSRKRSSSL
850 860 870 880 890 900
XP_016 GGSTGSTPSSSISSKSNSEDPFPQPERQKQQQPLALTQQEQQQQPLTLPQQQRSQQQPRC
910 920 930 940 950 960
>--
initn: 227 init1: 138 opt: 324 Z-score: 331.9 bits: 72.3 E(85289): 9.5e-12
Smith-Waterman score: 324; 32.5% identity (63.7% similar) in 212 aa overlap (16-204:5-210)
10 20 30 40 50
pF1KE2 MLLCTARLVGLQLLISCCW---AFACHSTESSPDFTLP--GDYLLAGLFPLHSGCL----
:::: :.. :.. .:: :: .:.::::.: :
XP_016 MAFYSCCWVLLALTWHTSAYGPDQRAQKKGDIILGGLFPIHFGVAAKDQ
10 20 30 40
60 70 80 90 100 110
pF1KE2 QVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSAN
... ::: . : : .: .:.. .::: ...::::.: :::::.::::...:.:. ..
XP_016 DLKSRPESVECIR---YNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSK
50 60 70 80 90 100
120 130 140 150 160
pF1KE2 VYATLRVLSLPGQHHIE-LQGDLL----HYSPTVLAVIGPDSTNRAATTAALLSPFLVPM
: .::. .:..:. :. : . .. :...::.: ... ....: ::. : .:.
XP_016 --ALEATLSFVAQNKIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQ
110 120 130 140 150 160
170 180 190 200 210
pF1KE2 LLEQIHKVHFLLHKDTV-AF-----NDNRDPLSSYNIIA---WDWNGPKWTFTVLGSSTW
. . ..: .:. .: ::... . .:: :.: :
XP_016 V-SYASSSRLLSNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGI
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE2 SPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKS
XP_016 EKFREEAEERDICIDFSELISQYSDEEEIQHVVEVIQNSTAKVIVVFSSGPDLEPLIKEI
230 240 250 260 270 280
587 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:18:53 2016 done: Mon Nov 7 20:18:55 2016
Total Scan time: 8.830 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]