Result of FASTA (omim) for
pF1KE2455
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2455, 479 aa
1>>>pF1KE2455 479 - 479 aa - 479 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3588+/-0.00039; mu= 1.4175+/- 0.025
mean_var=304.0754+/-61.842, 0's: 0 Z-trim(122.0): 249 B-trim: 87 in 1/55
Lambda= 0.073550
statistics sampled from 39147 (39450) to 39147 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.463), width: 16
Scan time: 7.980
The best scores are: opt bits E(85289)
NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 3268 360.2 7e-99
NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484) 3224 355.6 1.8e-97
NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505) 3224 355.6 1.9e-97
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 3205 353.6 7.3e-97
NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 2658 295.4 1.9e-79
NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 2658 295.4 1.9e-79
NP_039236 (OMIM: 167410,268220) paired box protein ( 518) 2521 281.0 5.4e-75
NP_002575 (OMIM: 167410,268220) paired box protein ( 520) 2507 279.5 1.5e-74
NP_001128726 (OMIM: 167410,268220) paired box prot ( 505) 2494 278.1 3.9e-74
NP_039230 (OMIM: 122880,148820,193500,268220,60659 ( 206) 1321 153.3 6.1e-37
NP_000429 (OMIM: 122880,148820,193500,268220,60659 ( 215) 1316 152.8 9.1e-37
NP_001244025 (OMIM: 167411,615560) paired box prot ( 457) 684 86.0 2.4e-16
NP_057953 (OMIM: 167414,615545) paired box protein ( 391) 682 85.7 2.5e-16
NP_006183 (OMIM: 167411,615560) paired box protein ( 534) 684 86.1 2.6e-16
NP_001267477 (OMIM: 167414,615545) paired box prot ( 362) 669 84.3 6.1e-16
NP_001267482 (OMIM: 167414,615545) paired box prot ( 319) 666 84.0 6.9e-16
XP_011510093 (OMIM: 167415,218700) PREDICTED: pair ( 500) 670 84.6 7e-16
NP_001267479 (OMIM: 167414,615545) paired box prot ( 295) 665 83.8 7.1e-16
NP_001267483 (OMIM: 167414,615545) paired box prot ( 348) 666 84.0 7.4e-16
NP_003457 (OMIM: 167415,218700) paired box protein ( 450) 668 84.3 7.6e-16
XP_005251538 (OMIM: 167414,615545) PREDICTED: pair ( 390) 665 83.9 8.6e-16
XP_011516198 (OMIM: 167414,615545) PREDICTED: pair ( 410) 664 83.9 9.5e-16
NP_001267478 (OMIM: 167414,615545) paired box prot ( 324) 660 83.3 1.1e-15
NP_001267481 (OMIM: 167414,615545) paired box prot ( 328) 660 83.3 1.1e-15
NP_001267476 (OMIM: 167414,615545) paired box prot ( 357) 660 83.4 1.2e-15
XP_011510092 (OMIM: 167415,218700) PREDICTED: pair ( 507) 660 83.5 1.5e-15
NP_003978 (OMIM: 120330,167409,191830,616002) pair ( 417) 656 83.0 1.7e-15
NP_003981 (OMIM: 120330,167409,191830,616002) pair ( 432) 656 83.0 1.8e-15
NP_000269 (OMIM: 120330,167409,191830,616002) pair ( 394) 655 82.9 1.8e-15
NP_003979 (OMIM: 120330,167409,191830,616002) pair ( 396) 655 82.9 1.8e-15
XP_016871774 (OMIM: 120330,167409,191830,616002) P ( 448) 656 83.1 1.8e-15
NP_003980 (OMIM: 120330,167409,191830,616002) pair ( 409) 655 82.9 1.8e-15
XP_016871773 (OMIM: 120330,167409,191830,616002) P ( 463) 656 83.1 1.9e-15
NP_001291498 (OMIM: 120330,167409,191830,616002) p ( 425) 655 82.9 1.9e-15
XP_016871776 (OMIM: 120330,167409,191830,616002) P ( 427) 655 82.9 1.9e-15
XP_016871775 (OMIM: 120330,167409,191830,616002) P ( 440) 655 82.9 1.9e-15
XP_016871778 (OMIM: 120330,167409,191830,616002) P ( 374) 649 82.2 2.7e-15
NP_006185 (OMIM: 167416,604625) paired box protein ( 341) 648 82.1 2.7e-15
XP_016871772 (OMIM: 120330,167409,191830,616002) P ( 483) 649 82.3 3.2e-15
XP_016871771 (OMIM: 120330,167409,191830,616002) P ( 483) 649 82.3 3.2e-15
XP_016871770 (OMIM: 120330,167409,191830,616002) P ( 496) 649 82.4 3.3e-15
XP_011516199 (OMIM: 167414,615545) PREDICTED: pair ( 409) 647 82.1 3.3e-15
XP_016871777 (OMIM: 120330,167409,191830,616002) P ( 424) 643 81.6 4.6e-15
NP_054698 (OMIM: 167415,218700) paired box protein ( 287) 636 80.7 5.8e-15
NP_039247 (OMIM: 167415,218700) paired box protein ( 321) 636 80.8 6.3e-15
NP_039246 (OMIM: 167415,218700) paired box protein ( 398) 638 81.1 6.3e-15
XP_016860368 (OMIM: 167415,218700) PREDICTED: pair ( 402) 638 81.1 6.4e-15
XP_011510096 (OMIM: 167415,218700) PREDICTED: pair ( 387) 636 80.9 7.2e-15
XP_011510094 (OMIM: 167415,218700) PREDICTED: pair ( 455) 637 81.0 7.5e-15
XP_016860367 (OMIM: 167415,218700) PREDICTED: pair ( 459) 637 81.0 7.5e-15
>>NP_852122 (OMIM: 122880,148820,193500,268220,606597) p (479 aa)
initn: 3268 init1: 3268 opt: 3268 Z-score: 1896.2 bits: 360.2 E(85289): 7e-99
Smith-Waterman score: 3268; 100.0% identity (100.0% similar) in 479 aa overlap (1-479:1-479)
10 20 30 40 50 60
pF1KE2 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE
370 380 390 400 410 420
430 440 450 460 470
pF1KE2 PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSKPWTF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSKPWTF
430 440 450 460 470
>>NP_852123 (OMIM: 122880,148820,193500,268220,606597) p (484 aa)
initn: 3224 init1: 3224 opt: 3224 Z-score: 1870.9 bits: 355.6 E(85289): 1.8e-97
Smith-Waterman score: 3224; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KE2 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE
370 380 390 400 410 420
430 440 450 460 470
pF1KE2 PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSKPWTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSAFHYLK
430 440 450 460 470 480
NP_852 PDIA
>>NP_852124 (OMIM: 122880,148820,193500,268220,606597) p (505 aa)
initn: 3224 init1: 3224 opt: 3224 Z-score: 1870.7 bits: 355.6 E(85289): 1.9e-97
Smith-Waterman score: 3224; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KE2 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE
370 380 390 400 410 420
430 440 450 460 470
pF1KE2 PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSKPWTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSAFHYLK
430 440 450 460 470 480
NP_852 PDIAWFQILLNTFDKSSGEEEDLEQ
490 500
>>NP_001120838 (OMIM: 122880,148820,193500,268220,606597 (483 aa)
initn: 2474 init1: 2474 opt: 3205 Z-score: 1860.0 bits: 353.6 E(85289): 7.3e-97
Smith-Waterman score: 3205; 99.8% identity (99.8% similar) in 474 aa overlap (1-474:1-473)
10 20 30 40 50 60
pF1KE2 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_001 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPK-VTTPDVEKKIEE
70 80 90 100 110
130 140 150 160 170 180
pF1KE2 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE
360 370 380 390 400 410
430 440 450 460 470
pF1KE2 PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSKPWTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSAFHYLK
420 430 440 450 460 470
NP_001 PDIA
480
>>NP_852126 (OMIM: 122880,148820,193500,268220,606597) p (403 aa)
initn: 2657 init1: 2657 opt: 2658 Z-score: 1547.3 bits: 295.4 E(85289): 1.9e-79
Smith-Waterman score: 2658; 98.2% identity (99.5% similar) in 399 aa overlap (1-399:1-399)
10 20 30 40 50 60
pF1KE2 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE
:::::::::::::::::::::::::::::::: .....
NP_852 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVPFIISSQISRK
370 380 390 400
430 440 450 460 470
pF1KE2 PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSKPWTF
>>NP_852125 (OMIM: 122880,148820,193500,268220,606597) p (407 aa)
initn: 2657 init1: 2657 opt: 2658 Z-score: 1547.2 bits: 295.4 E(85289): 1.9e-79
Smith-Waterman score: 2658; 98.2% identity (99.5% similar) in 399 aa overlap (1-399:1-399)
10 20 30 40 50 60
pF1KE2 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE
:::::::::::::::::::::::::::::::: .....
NP_852 HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVPFIISSQISLGFKSF
370 380 390 400
430 440 450 460 470
pF1KE2 PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSKPWTF
>>NP_039236 (OMIM: 167410,268220) paired box protein Pax (518 aa)
initn: 2362 init1: 1079 opt: 2521 Z-score: 1467.4 bits: 281.0 E(85289): 5.4e-75
Smith-Waterman score: 2521; 77.3% identity (90.3% similar) in 484 aa overlap (1-477:1-472)
10 20 30 40 50 60
pF1KE2 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
:..: :.:::::::.:::::::.:::::::::::::::::::::::::::::::::::::
NP_039 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
::::::::::::::::::::::::::::::::::::::::::::::.::.::::::::::
NP_039 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEE-EADLERKEAEE
:::::::::::::::.::::. :::.::::::::::.:: :::: ::: ::: :. ..
NP_039 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEAD---KKEDD
130 140 150 160 170
180 190 200 210 220 230
pF1KE2 SEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFE
.::::::::::::..... . :::::..:::::::::::::::::::::::::::.:::
NP_039 GEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 RTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAM
::::::::::::::::.::::::::::::::::::::::::::: :::::.:::::::.:
NP_039 RTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNP---DSSSAYCL
:::: ::: ...: :.: : : .:::::::::::::.::. . . :.::::
NP_039 PTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY--
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 PSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLT
..::.::::.:::. :..::: ::: ..::::::::..: : ..:: :::.:...:::
NP_039 -GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISPLH
360 370 380 390 400
420 430 440 450 460 470
pF1KE2 GGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSK-
:::. .:..::::::: : .: :::::::.::::::::::::.:::.::::::::::.
NP_039 GGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSEC
410 420 430 440 450 460
pF1KE2 --PWTF
::
NP_039 LVPWASPVPIPSPTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT
470 480 490 500 510
>>NP_002575 (OMIM: 167410,268220) paired box protein Pax (520 aa)
initn: 2327 init1: 1050 opt: 2507 Z-score: 1459.3 bits: 279.5 E(85289): 1.5e-74
Smith-Waterman score: 2507; 77.0% identity (89.9% similar) in 486 aa overlap (1-477:1-474)
10 20 30 40 50 60
pF1KE2 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
:..: :.:::::::.:::::::.:::::::::::::::::::::::::::::::::::::
NP_002 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
::::::::::::::::::::::::::::::::::::::::::::::.::.::::::::::
NP_002 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA
:::::::::::::::.::::. :::.:::: ::::::.:: :::: ::: ::: :.
NP_002 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE
130 140 150 160 170
180 190 200 210 220 230
pF1KE2 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA
...::::::::::::..... . :::::..:::::::::::::::::::::::::::.:
NP_002 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT
::::::::::::::::::.::::::::::::::::::::::::::: :::::.:::::::
NP_002 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNP---DSSSAY
.::::: ::: ...: :.: : : .:::::::::::::.::. . . :.::::
NP_002 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP
..::.::::.:::. :..::: ::: ..::::::::..: : ..:: :::.:...::
NP_002 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISP
360 370 380 390 400
420 430 440 450 460 470
pF1KE2 LTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS
: :::. .:..::::::: : .: :::::::.::::::::::::.:::.::::::::::
NP_002 LHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS
410 420 430 440 450 460
pF1KE2 K---PWTF
. ::
NP_002 ECLVPWASPVPIPSPTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT
470 480 490 500 510 520
>>NP_001128726 (OMIM: 167410,268220) paired box protein (505 aa)
initn: 2323 init1: 1050 opt: 2494 Z-score: 1452.0 bits: 278.1 E(85289): 3.9e-74
Smith-Waterman score: 2494; 77.3% identity (90.4% similar) in 480 aa overlap (1-474:1-468)
10 20 30 40 50 60
pF1KE2 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
:..: :.:::::::.:::::::.:::::::::::::::::::::::::::::::::::::
NP_001 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
::::::::::::::::::::::::::::::::::::::::::::::.::.::::::::::
NP_001 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA
:::::::::::::::.::::. :::.:::: ::::::.:: :::: ::: ::: :.
NP_001 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE
130 140 150 160 170
180 190 200 210 220 230
pF1KE2 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA
...::::::::::::..... . :::::..:::::::::::::::::::::::::::.:
NP_001 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT
::::::::::::::::::.::::::::::::::::::::::::::: :::::.:::::::
NP_001 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNP---DSSSAY
.::::: ::: ...: :.: : : .:::::::::::::.::. . . :.::::
NP_001 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP
..::.::::.:::. :..::: ::: ..::::::::..: : ..:: :::.:...::
NP_001 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISP
360 370 380 390 400
420 430 440 450 460 470
pF1KE2 LTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS
: :::. .:..::::::: : .: :::::::.::::::::::::.:::.:::::::::.
NP_001 LHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQT
410 420 430 440 450 460
pF1KE2 KPWTF
NP_001 AVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY
470 480 490 500
>>NP_039230 (OMIM: 122880,148820,193500,268220,606597) p (206 aa)
initn: 1321 init1: 1321 opt: 1321 Z-score: 784.2 bits: 153.3 E(85289): 6.1e-37
Smith-Waterman score: 1321; 99.0% identity (100.0% similar) in 198 aa overlap (1-198:1-198)
10 20 30 40 50 60
pF1KE2 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER
:::::::::::::::..:
NP_039 EKKAKHSIDGILSERGKALVSGVSSH
190 200
479 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:08:35 2016 done: Mon Nov 7 20:08:36 2016
Total Scan time: 7.980 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]