Result of FASTA (ccds) for
pF1KE2328
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2328, 355 aa
1>>>pF1KE2328 355 - 355 aa - 355 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3874+/-0.000944; mu= 16.1242+/- 0.057
mean_var=67.9783+/-13.799, 0's: 0 Z-trim(104.7): 34 B-trim: 40 in 1/49
Lambda= 0.155557
statistics sampled from 8017 (8036) to 8017 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.247), width: 16
Scan time: 2.510
The best scores are: opt bits E(32554)
CCDS6345.1 FBXO32 gene_id:114907|Hs108|chr8 ( 355) 2415 551.1 5.4e-157
CCDS5952.1 FBXO25 gene_id:26260|Hs108|chr8 ( 358) 1544 355.6 3.8e-98
CCDS5953.1 FBXO25 gene_id:26260|Hs108|chr8 ( 367) 1410 325.5 4.3e-89
CCDS5954.1 FBXO25 gene_id:26260|Hs108|chr8 ( 291) 1221 283.0 2.1e-76
CCDS56553.1 FBXO32 gene_id:114907|Hs108|chr8 ( 262) 990 231.2 7.7e-61
>>CCDS6345.1 FBXO32 gene_id:114907|Hs108|chr8 (355 aa)
initn: 2415 init1: 2415 opt: 2415 Z-score: 2932.1 bits: 551.1 E(32554): 5.4e-157
Smith-Waterman score: 2415; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355)
10 20 30 40 50 60
pF1KE2 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYNKENLFNSLNYDVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYNKENLFNSLNYDVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 AKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 YVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 VQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 SDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKL
250 260 270 280 290 300
310 320 330 340 350
pF1KE2 VRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 VRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF
310 320 330 340 350
>>CCDS5952.1 FBXO25 gene_id:26260|Hs108|chr8 (358 aa)
initn: 1545 init1: 1388 opt: 1544 Z-score: 1875.6 bits: 355.6 E(32554): 3.8e-98
Smith-Waterman score: 1544; 61.4% identity (83.6% similar) in 360 aa overlap (1-355:1-358)
10 20 30 40 50
pF1KE2 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKE---VYNKEN--LFNSL
:::::::::::: .:.:: ::::: :. .. . .. :: . :.:. .::.
CCDS59 MPFLGQDWRSPGWSWIKTEDGWKRC--ESCSQKLERENNRCNISHSIILNSEDGEIFNNE
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 NYDVAAKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILD
... :.:::::: . . :.:: :..:::::::: :::::::::::::::::::::.:: :
CCDS59 EHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 SRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYT
:::::::.::.::::::::::::.::::..:::.:.: :::.:..: :::..::: : .
CCDS59 IRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 SLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLN
.:: :.. :::::::::::.:. :.:::: :::::...:.:. . .:::..:::: . :
CCDS59 TLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 IMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKK
:. :.::: :...:::..: :..::::: ::::::::::.:.:. ..::::.::...::
CCDS59 ILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 MYFKLVRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF
::: : . :: ::::::::..:.:: :: :: . ::::: .:.:: . .::: ::.::::
CCDS59 MYFALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF
300 310 320 330 340 350
>>CCDS5953.1 FBXO25 gene_id:26260|Hs108|chr8 (367 aa)
initn: 1411 init1: 1254 opt: 1410 Z-score: 1712.9 bits: 325.5 E(32554): 4.3e-89
Smith-Waterman score: 1516; 59.9% identity (81.6% similar) in 369 aa overlap (1-355:1-367)
10 20 30 40 50
pF1KE2 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKE---VYNKEN--LFNSL
:::::::::::: .:.:: ::::: :. .. . .. :: . :.:. .::.
CCDS59 MPFLGQDWRSPGWSWIKTEDGWKRC--ESCSQKLERENNRCNISHSIILNSEDGEIFNNE
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 NYDVAAKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILD
... :.:::::: . . :.:: :..:::::::: :::::::::::::::::::::.:: :
CCDS59 EHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 SRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYT
:::::::.::.::::::::::::.::::..:::.:.: :::.:..: :::..::: : .
CCDS59 IRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 SLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLN
.:: :.. :::::::::::.:. :.:::: :::::...:.:. . .:::..:::: . :
CCDS59 TLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 IMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKK
:. :.::: :...:::..: :..::::: ::::::::::.:.:. ..::::.::...::
CCDS59 ILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKL
240 250 260 270 280 290
300 310 320 330 340
pF1KE2 MYFKLVRCYPRKEQYGDTLQLCKHCHILSWKG---------TDHPCTANNPESCSVSLSP
::: : . :: ::::::::..:.:: :: :: . ::::: .:.:: . .::
CCDS59 MYFALQKHYPAKEQYGDTLHFCRHCSILFWKDYHLALLFKDSGHPCTAADPDSCFTPVSP
300 310 320 330 340 350
350
pF1KE2 QDFINLFKF
: ::.::::
CCDS59 QHFIDLFKF
360
>>CCDS5954.1 FBXO25 gene_id:26260|Hs108|chr8 (291 aa)
initn: 1221 init1: 1221 opt: 1221 Z-score: 1485.2 bits: 283.0 E(32554): 2.1e-76
Smith-Waterman score: 1221; 65.0% identity (87.5% similar) in 263 aa overlap (93-355:29-291)
70 80 90 100 110 120
pF1KE2 KRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFNYV
.:::::::::::::::::.:: : ::::::
CCDS59 MEKYSIMKSMNMHRKKGKRTILEMTQILKRHGYCTLGEAFNRLDFSSAIQDIRRFNYV
10 20 30 40 50
130 140 150 160 170 180
pF1KE2 VRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQ
:.::.::::::::::::.::::..:::.:.: :::.:..: :::..::: : ..:: :..
CCDS59 VKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCILIR
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE2 RVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRLSD
:::::::::::.:. :.:::: :::::...:.:. . .:::..:::: . ::. :.::
CCDS59 GVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNILYRFSD
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE2 GRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKLVR
: :...:::..: :..::::: ::::::::::.:.:. ..::::.::...:: ::: : .
CCDS59 GWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFALQK
180 190 200 210 220 230
310 320 330 340 350
pF1KE2 CYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF
:: ::::::::..:.:: :: :: . ::::: .:.:: . .::: ::.::::
CCDS59 HYPAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF
240 250 260 270 280 290
>>CCDS56553.1 FBXO32 gene_id:114907|Hs108|chr8 (262 aa)
initn: 990 init1: 990 opt: 990 Z-score: 1205.7 bits: 231.2 E(32554): 7.7e-61
Smith-Waterman score: 1640; 73.8% identity (73.8% similar) in 355 aa overlap (1-355:1-262)
10 20 30 40 50 60
pF1KE2 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYNKENLFNSLNYDVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYNKENLFNSLNYDVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTL
::::
CCDS56 YVVR--------------------------------------------------------
190 200 210 220 230 240
pF1KE2 VQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRL
:::::::::::::::::::::::
CCDS56 -------------------------------------PAFKGLTFTDLPLCLQLNIMQRL
130 140
250 260 270 280 290 300
pF1KE2 SDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKL
150 160 170 180 190 200
310 320 330 340 350
pF1KE2 VRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF
210 220 230 240 250 260
355 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:53:36 2016 done: Sun Nov 6 15:53:37 2016
Total Scan time: 2.510 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]