Result of FASTA (omim) for
pF1KE2049
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2049, 671 aa
1>>>pF1KE2049 671 - 671 aa - 671 aa
Library: /omim/omim.rfq.tfa
64536644 residues in 91102 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.8161+/-0.000658; mu= -20.3536+/- 0.039
mean_var=960.7288+/-219.771, 0's: 0 Z-trim(116.6): 224 B-trim: 1620 in 1/53
Lambda= 0.041378
statistics sampled from 28548 (28767) to 28548 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.316), width: 16
Scan time: 5.430
The best scores are: opt bits E(91102)
NP_001341859 (OMIM: 603453) receptor-interacting s ( 671) 4511 286.4 2.5e-76
NP_003795 (OMIM: 603453) receptor-interacting seri ( 671) 4511 286.4 2.5e-76
NP_001341860 (OMIM: 603453) receptor-interacting s ( 625) 3511 226.7 2.2e-58
NP_001341861 (OMIM: 603453) receptor-interacting s ( 508) 3448 222.8 2.7e-57
XP_016866892 (OMIM: 603453) receptor-interacting s ( 508) 3448 222.8 2.7e-57
NP_001341863 (OMIM: 603453) receptor-interacting s ( 508) 3448 222.8 2.7e-57
NP_001341862 (OMIM: 603453) receptor-interacting s ( 508) 3448 222.8 2.7e-57
NP_001303990 (OMIM: 603453) receptor-interacting s ( 508) 3448 222.8 2.7e-57
XP_016866893 (OMIM: 603453) receptor-interacting s ( 382) 2485 165.1 4.6e-40
XP_006715300 (OMIM: 603453) receptor-interacting s ( 356) 2040 138.5 4.4e-32
XP_016866894 (OMIM: 603453) receptor-interacting s ( 356) 2040 138.5 4.4e-32
NP_003812 (OMIM: 603455) receptor-interacting seri ( 540) 466 44.8 0.0011
>>NP_001341859 (OMIM: 603453) receptor-interacting serin (671 aa)
initn: 4511 init1: 4511 opt: 4511 Z-score: 1491.9 bits: 286.4 E(91102): 2.5e-76
Smith-Waterman score: 4511; 100.0% identity (100.0% similar) in 671 aa overlap (1-671:1-671)
10 20 30 40 50 60
pF1KE2 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
610 620 630 640 650 660
670
pF1KE2 LLSSLIYVSQN
:::::::::::
NP_001 LLSSLIYVSQN
670
>>NP_003795 (OMIM: 603453) receptor-interacting serine/t (671 aa)
initn: 4511 init1: 4511 opt: 4511 Z-score: 1491.9 bits: 286.4 E(91102): 2.5e-76
Smith-Waterman score: 4511; 100.0% identity (100.0% similar) in 671 aa overlap (1-671:1-671)
10 20 30 40 50 60
pF1KE2 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
610 620 630 640 650 660
670
pF1KE2 LLSSLIYVSQN
:::::::::::
NP_003 LLSSLIYVSQN
670
>>NP_001341860 (OMIM: 603453) receptor-interacting serin (625 aa)
initn: 3509 init1: 3509 opt: 3511 Z-score: 1169.6 bits: 226.7 E(91102): 2.2e-58
Smith-Waterman score: 4101; 93.1% identity (93.1% similar) in 671 aa overlap (1-671:1-625)
10 20 30 40 50 60
pF1KE2 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAE-------------
70 80 90 100
130 140 150 160 170 180
pF1KE2 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
:::::::::::::::::::::::::::
NP_001 ---------------------------------IADLGLASFKMWSKLNNEEHNELREVD
110 120 130
190 200 210 220 230 240
pF1KE2 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE2 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE2 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE2 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE2 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
380 390 400 410 420 430
490 500 510 520 530 540
pF1KE2 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
440 450 460 470 480 490
550 560 570 580 590 600
pF1KE2 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
500 510 520 530 540 550
610 620 630 640 650 660
pF1KE2 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
560 570 580 590 600 610
670
pF1KE2 LLSSLIYVSQN
:::::::::::
NP_001 LLSSLIYVSQN
620
>>NP_001341861 (OMIM: 603453) receptor-interacting serin (508 aa)
initn: 3448 init1: 3448 opt: 3448 Z-score: 1150.2 bits: 222.8 E(91102): 2.7e-57
Smith-Waterman score: 3448; 100.0% identity (100.0% similar) in 508 aa overlap (164-671:1-508)
140 150 160 170 180 190
pF1KE2 VIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYM
::::::::::::::::::::::::::::::
NP_001 MWSKLNNEEHNELREVDGTAKKNGGTLYYM
10 20 30
200 210 220 230 240 250
pF1KE2 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE2 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE2 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE2 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE2 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE2 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE2 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE2 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
460 470 480 490 500
>>XP_016866892 (OMIM: 603453) receptor-interacting serin (508 aa)
initn: 3448 init1: 3448 opt: 3448 Z-score: 1150.2 bits: 222.8 E(91102): 2.7e-57
Smith-Waterman score: 3448; 100.0% identity (100.0% similar) in 508 aa overlap (164-671:1-508)
140 150 160 170 180 190
pF1KE2 VIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYM
::::::::::::::::::::::::::::::
XP_016 MWSKLNNEEHNELREVDGTAKKNGGTLYYM
10 20 30
200 210 220 230 240 250
pF1KE2 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE2 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE2 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE2 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE2 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE2 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE2 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE2 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
460 470 480 490 500
>>NP_001341863 (OMIM: 603453) receptor-interacting serin (508 aa)
initn: 3448 init1: 3448 opt: 3448 Z-score: 1150.2 bits: 222.8 E(91102): 2.7e-57
Smith-Waterman score: 3448; 100.0% identity (100.0% similar) in 508 aa overlap (164-671:1-508)
140 150 160 170 180 190
pF1KE2 VIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYM
::::::::::::::::::::::::::::::
NP_001 MWSKLNNEEHNELREVDGTAKKNGGTLYYM
10 20 30
200 210 220 230 240 250
pF1KE2 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE2 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE2 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE2 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE2 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE2 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE2 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE2 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
460 470 480 490 500
>>NP_001341862 (OMIM: 603453) receptor-interacting serin (508 aa)
initn: 3448 init1: 3448 opt: 3448 Z-score: 1150.2 bits: 222.8 E(91102): 2.7e-57
Smith-Waterman score: 3448; 100.0% identity (100.0% similar) in 508 aa overlap (164-671:1-508)
140 150 160 170 180 190
pF1KE2 VIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYM
::::::::::::::::::::::::::::::
NP_001 MWSKLNNEEHNELREVDGTAKKNGGTLYYM
10 20 30
200 210 220 230 240 250
pF1KE2 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE2 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE2 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE2 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE2 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE2 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE2 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE2 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
460 470 480 490 500
>>NP_001303990 (OMIM: 603453) receptor-interacting serin (508 aa)
initn: 3448 init1: 3448 opt: 3448 Z-score: 1150.2 bits: 222.8 E(91102): 2.7e-57
Smith-Waterman score: 3448; 100.0% identity (100.0% similar) in 508 aa overlap (164-671:1-508)
140 150 160 170 180 190
pF1KE2 VIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYM
::::::::::::::::::::::::::::::
NP_001 MWSKLNNEEHNELREVDGTAKKNGGTLYYM
10 20 30
200 210 220 230 240 250
pF1KE2 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE2 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE2 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE2 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE2 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE2 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE2 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE2 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
460 470 480 490 500
>>XP_016866893 (OMIM: 603453) receptor-interacting serin (382 aa)
initn: 2484 init1: 2484 opt: 2485 Z-score: 840.8 bits: 165.1 E(91102): 4.6e-40
Smith-Waterman score: 2485; 97.9% identity (98.7% similar) in 376 aa overlap (296-671:7-382)
270 280 290 300 310 320
pF1KE2 LCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENAVVKRMQSLQLDC
:. .. :::::::::::::::::::::
XP_016 MSSEYISIMFKINFKKKEYSNENAVVKRMQSLQLDC
10 20 30
330 340 350 360 370 380
pF1KE2 VAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPSLQSKLQDEANYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPSLQSKLQDEANYH
40 50 60 70 80 90
390 400 410 420 430 440
pF1KE2 LYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTEGKGTAYSSAASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTEGKGTAYSSAASH
100 110 120 130 140 150
450 460 470 480 490 500
pF1KE2 GNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPIPSHMPSLHNIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPIPSHMPSLHNIPV
160 170 180 190 200 210
510 520 530 540 550 560
pF1KE2 PETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTSSSLLDSTNTNFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTSSSLLDSTNTNFK
220 230 240 250 260 270
570 580 590 600 610 620
pF1KE2 EEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLK
280 290 300 310 320 330
630 640 650 660 670
pF1KE2 EKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
340 350 360 370 380
>>XP_006715300 (OMIM: 603453) receptor-interacting serin (356 aa)
initn: 2040 init1: 2040 opt: 2040 Z-score: 697.5 bits: 138.5 E(91102): 4.4e-32
Smith-Waterman score: 2040; 99.0% identity (99.7% similar) in 309 aa overlap (1-309:1-309)
10 20 30 40 50 60
pF1KE2 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
:::::.: .
XP_006 VKSLKNEQTKISKDIEDRKNMTNTLDVTETQDTLHLITAAHLPAAPSNRRAPTCRT
310 320 330 340 350
671 residues in 1 query sequences
64536644 residues in 91102 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Jun 3 14:39:56 2018 done: Sun Jun 3 14:39:57 2018
Total Scan time: 5.430 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]