FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1716, 220 aa
  1>>>pF1KE1716     220 - 220 aa - 220 aa
Library: human.CCDS.faa
  18921897 residues in 33420 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.8647+/-0.000661; mu= 16.9967+/- 0.040
 mean_var=66.9911+/-13.690, 0's: 0 Z-trim(110.6): 15  B-trim: 61 in 1/48
 Lambda= 0.156699
 statistics sampled from 11866 (11878) to 11866 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.355), width:  16
 Scan time:  0.980

The best scores are:                                      opt bits E(33420)
CCDS2361.1 CD28 gene_id:940|Hs109|chr2             ( 220) 1503 347.9   3e-96
CCDS58749.1 CD28 gene_id:940|Hs109|chr2            ( 101)  615 146.9 4.5e-36
CCDS2362.1 CTLA4 gene_id:1493|Hs109|chr2           ( 223)  280 71.4 5.2e-13


>>CCDS2361.1 CD28 gene_id:940|Hs109|chr2                  (220 aa)
 initn: 1503 init1: 1503 opt: 1503  Z-score: 1841.6  bits: 347.9 E(33420): 3e-96
Smith-Waterman score: 1503; 100.0% identity (100.0% similar) in 220 aa overlap (1-220:1-220)

               10        20        30        40        50        60
pF1KE1 MLRLLLALNLFPSIQVTGNKILVKQSPMLVAYDNAVNLSCKYSYNLFSREFRASLHKGLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 MLRLLLALNLFPSIQVTGNKILVKQSPMLVAYDNAVNLSCKYSYNLFSREFRASLHKGLD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 SAVEVCVVYGNYSQQLQVYSKTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 SAVEVCVVYGNYSQQLQVYSKTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 PYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKPFWVLVVVGGVLACYSLLVTVAFIIFWVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 PYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKPFWVLVVVGGVLACYSLLVTVAFIIFWVR
              130       140       150       160       170       180

              190       200       210       220
pF1KE1 SKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPPRDFAAYRS
       ::::::::::::::::::::::::::::::::::::::::
CCDS23 SKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPPRDFAAYRS
              190       200       210       220

>>CCDS58749.1 CD28 gene_id:940|Hs109|chr2                 (101 aa)
 initn: 615 init1: 615 opt: 615  Z-score: 761.3  bits: 146.9 E(33420): 4.5e-36
Smith-Waterman score: 615; 97.7% identity (98.9% similar) in 88 aa overlap (133-220:14-101)

            110       120       130       140       150       160  
pF1KE1 YVNQTDIYFCKIEVMYPPPYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKPFWVLVVVGGV
                                     :.: ::::::::::::::::::::::::::
CCDS58                  MLRLLLALNLFPSIQVTGKHLCPSPLFPGPSKPFWVLVVVGGV
                                10        20        30        40   

            170       180       190       200       210       220
pF1KE1 LACYSLLVTVAFIIFWVRSKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPPRDFAAYRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LACYSLLVTVAFIIFWVRSKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPPRDFAAYRS
            50        60        70        80        90       100 

>>CCDS2362.1 CTLA4 gene_id:1493|Hs109|chr2                (223 aa)
 initn: 150 init1: 128 opt: 280  Z-score: 347.3  bits: 71.4 E(33420): 5.2e-13
Smith-Waterman score: 280; 31.4% identity (61.4% similar) in 210 aa overlap (5-212:24-221)

                                  10        20        30         40
pF1KE1                    MLRLLLALNLFPSIQVTGNKILVKQSPMLVAYDNAV-NLSC
                              :: . ::  : :  . . : :  ...: . .. .. :
CCDS23 MACLGFQRHKAQLNLATRTWPCTLLFFLLF--IPVFCKAMHVAQPAVVLASSRGIASFVC
               10        20        30          40        50        

               50        60         70        80        90         
pF1KE1 KYSYNLFSREFRASLHKGLDSAV-EVCVVYGNYSQQLQVYSKTGFNCDGKLGNESVTFYL
       .:.    . : :... .  :: : :::..   ....:   . .   : :  ....:.. .
CCDS23 EYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDS--ICTGTSSGNQVNLTI
       60        70        80        90       100         110      

     100       110       120       130       140       150         
pF1KE1 QNLYVNQTDIYFCKIEVMYPPPYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKPFWVLVVV
       :.: . .: .:.::.:.::::::  .  .::: :.:   . ::.  :      .:.:..:
CCDS23 QGLRAMDTGLYICKVELMYPPPYYLG-IGNGTQIYVIDPEPCPDSDFL-----LWILAAV
        120       130       140        150       160            170

     160       170       180       190       200       210         
pF1KE1 GGVLACYSLLVTVAFIIFWVRSKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPPRDFAAYR
       .. :  ::.:.: :  .  . .::: :  . :..: : .:   .:..:::  :       
CCDS23 SSGLFFYSFLLT-AVSLSKMLKKRSPLTTGVYVKMPPTEP-ECEKQFQPYFIPIN     
              180        190       200        210       220        

     220
pF1KE1 S




220 residues in 1 query   sequences
18921897 residues in 33420 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Jul  3 20:45:53 2020 done: Fri Jul  3 20:45:53 2020
 Total Scan time:  0.980 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]