Result of FASTA (omim) for
pF1KE1090
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1090, 595 aa
1>>>pF1KE1090 595 - 595 aa - 595 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2656+/-0.000346; mu= 20.1654+/- 0.022
mean_var=81.4989+/-16.439, 0's: 0 Z-trim(114.8): 65 B-trim: 0 in 0/54
Lambda= 0.142069
statistics sampled from 24839 (24905) to 24839 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.292), width: 16
Scan time: 9.230
The best scores are: opt bits E(85289)
NP_002553 (OMIM: 602566) P2X purinoceptor 7 [Homo ( 595) 4176 865.9 0
XP_011536721 (OMIM: 602566) PREDICTED: P2X purinoc ( 491) 3479 723.0 5.6e-208
XP_016874853 (OMIM: 602566) PREDICTED: P2X purinoc ( 475) 3177 661.1 2.4e-189
XP_016874854 (OMIM: 602566) PREDICTED: P2X purinoc ( 475) 3177 661.1 2.4e-189
XP_016874855 (OMIM: 602566) PREDICTED: P2X purinoc ( 344) 2445 510.9 2.7e-144
XP_016874856 (OMIM: 602566) PREDICTED: P2X purinoc ( 344) 2445 510.9 2.7e-144
XP_011536722 (OMIM: 602566) PREDICTED: P2X purinoc ( 306) 2138 448.0 2.2e-125
NP_002551 (OMIM: 600846) P2X purinoceptor 4 isofor ( 388) 1132 241.9 3e-63
NP_001243725 (OMIM: 600846) P2X purinoceptor 4 iso ( 404) 1070 229.2 2.1e-59
NP_001248327 (OMIM: 600846) P2X purinoceptor 4 iso ( 341) 1067 228.5 2.8e-59
NP_002549 (OMIM: 600845,609821) P2X purinoceptor 1 ( 399) 978 210.3 9.8e-54
XP_011522201 (OMIM: 600845,609821) PREDICTED: P2X ( 411) 935 201.5 4.5e-51
NP_733782 (OMIM: 600844,608224) P2X purinoceptor 2 ( 471) 831 180.3 1.3e-44
NP_777362 (OMIM: 600844,608224) P2X purinoceptor 2 ( 404) 822 178.4 4.2e-44
XP_016874524 (OMIM: 600844,608224) PREDICTED: P2X ( 462) 822 178.4 4.6e-44
NP_002550 (OMIM: 600843) P2X purinoceptor 3 [Homo ( 397) 808 175.5 3e-43
XP_011543372 (OMIM: 600843) PREDICTED: P2X purinoc ( 397) 808 175.5 3e-43
XP_011543371 (OMIM: 600843) PREDICTED: P2X purinoc ( 397) 808 175.5 3e-43
XP_011543373 (OMIM: 600843) PREDICTED: P2X purinoc ( 395) 806 175.1 4e-43
XP_011543374 (OMIM: 600843) PREDICTED: P2X purinoc ( 323) 803 174.4 5.3e-43
NP_002552 (OMIM: 602836) P2X purinoceptor 5 isofor ( 422) 799 173.7 1.1e-42
XP_005266213 (OMIM: 600844,608224) PREDICTED: P2X ( 430) 799 173.7 1.2e-42
XP_005266212 (OMIM: 600844,608224) PREDICTED: P2X ( 488) 799 173.7 1.3e-42
NP_733783 (OMIM: 600844,608224) P2X purinoceptor 2 ( 497) 799 173.7 1.3e-42
NP_001191448 (OMIM: 602836) P2X purinoceptor 5 iso ( 421) 789 171.6 4.7e-42
NP_005437 (OMIM: 608077) P2X purinoceptor 6 isofor ( 441) 780 169.8 1.7e-41
XP_011522199 (OMIM: 600845,609821) PREDICTED: P2X ( 419) 774 168.5 3.9e-41
NP_001153026 (OMIM: 608077) P2X purinoceptor 6 iso ( 415) 752 164.0 8.9e-40
NP_001269094 (OMIM: 600844,608224) P2X purinocepto ( 349) 750 163.5 1e-39
XP_011522198 (OMIM: 600845,609821) PREDICTED: P2X ( 431) 731 159.7 1.8e-38
XP_011528800 (OMIM: 608077) PREDICTED: P2X purinoc ( 539) 713 156.1 2.8e-37
XP_016884557 (OMIM: 608077) PREDICTED: P2X purinoc ( 393) 710 155.4 3.3e-37
NP_057402 (OMIM: 600844,608224) P2X purinoceptor 2 ( 447) 702 153.8 1.1e-36
NP_777361 (OMIM: 600844,608224) P2X purinoceptor 2 ( 379) 699 153.1 1.6e-36
NP_001248326 (OMIM: 600846) P2X purinoceptor 4 iso ( 361) 687 150.6 8.2e-36
XP_011528802 (OMIM: 608077) PREDICTED: P2X purinoc ( 513) 685 150.4 1.4e-35
XP_011536718 (OMIM: 600846) PREDICTED: P2X purinoc ( 258) 680 149.1 1.7e-35
XP_011533088 (OMIM: 600844,608224) PREDICTED: P2X ( 473) 670 147.3 1.1e-34
NP_036358 (OMIM: 600844,608224) P2X purinoceptor 2 ( 399) 666 146.4 1.8e-34
NP_001191449 (OMIM: 602836) P2X purinoceptor 5 iso ( 398) 640 141.0 7e-33
XP_005266211 (OMIM: 600844,608224) PREDICTED: P2X ( 512) 640 141.1 8.5e-33
NP_778255 (OMIM: 602836) P2X purinoceptor 5 isofor ( 397) 630 139.0 2.9e-32
XP_016884558 (OMIM: 608077) PREDICTED: P2X purinoc ( 391) 609 134.7 5.7e-31
XP_016884556 (OMIM: 608077) PREDICTED: P2X purinoc ( 417) 609 134.7 6e-31
XP_011543375 (OMIM: 600843) PREDICTED: P2X purinoc ( 233) 589 130.4 6.6e-30
XP_016884562 (OMIM: 608077) PREDICTED: P2X purinoc ( 290) 571 126.8 1e-28
XP_016884564 (OMIM: 608077) PREDICTED: P2X purinoc ( 290) 571 126.8 1e-28
XP_016884561 (OMIM: 608077) PREDICTED: P2X purinoc ( 290) 571 126.8 1e-28
XP_016884565 (OMIM: 608077) PREDICTED: P2X purinoc ( 290) 571 126.8 1e-28
XP_016884563 (OMIM: 608077) PREDICTED: P2X purinoc ( 290) 571 126.8 1e-28
>>NP_002553 (OMIM: 602566) P2X purinoceptor 7 [Homo sapi (595 aa)
initn: 4176 init1: 4176 opt: 4176 Z-score: 4625.8 bits: 865.9 E(85289): 0
Smith-Waterman score: 4176; 99.7% identity (100.0% similar) in 595 aa overlap (1-595:1-595)
10 20 30 40 50 60
pF1KE1 MPACCSCSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVCFALVSDKLYQRKEPVISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MPACCSCSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVCFALVSDKLYQRKEPVISS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVHEGNQKTCEVSAWCPIEAVEEAPRPA
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
NP_002 EYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIFRETGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIFRETGD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 NFSDVAIQGGIMGIEIYWDCNLDRWFHHCHPKYSFRRLDDKTTNVSLYPGYNFRYAKYYK
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
NP_002 NFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 NCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDS
490 500 510 520 530 540
550 560 570 580 590
pF1KE1 TNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
550 560 570 580 590
>>XP_011536721 (OMIM: 602566) PREDICTED: P2X purinocepto (491 aa)
initn: 3479 init1: 3479 opt: 3479 Z-score: 3854.8 bits: 723.0 E(85289): 5.6e-208
Smith-Waterman score: 3479; 99.6% identity (100.0% similar) in 491 aa overlap (105-595:1-491)
80 90 100 110 120 130
pF1KE1 IVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCPEYPTRRTLCSSDRG
::::::::::::::::::::::::::::::
XP_011 MTNFLKTEGQEQRLCPEYPTRRTLCSSDRG
10 20 30
140 150 160 170 180 190
pF1KE1 CKKGWMDPQSKGIQTGRCVVHEGNQKTCEVSAWCPIEAVEEAPRPALLNSAENFTVLIKN
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_011 CKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPALLNSAENFTVLIKN
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE1 NIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIFRETGDNFSDVAIQGGIMGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIFRETGDNFSDVAIQGGIMGI
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE1 EIYWDCNLDRWFHHCHPKYSFRRLDDKTTNVSLYPGYNFRYAKYYKENNVEKRTLIKVFG
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYKENNVEKRTLIKVFG
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE1 IRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCC
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE1 QPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAM
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE1 DFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCGSCLPSQLPESHRCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCGSCLPSQLPESHRCL
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE1 EELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDSTNSRLRHCAYRCYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDSTNSRLRHCAYRCYA
400 410 420 430 440 450
560 570 580 590
pF1KE1 TWRFGSQDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
:::::::::::::::::::::::::::::::::::::::::
XP_011 TWRFGSQDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
460 470 480 490
>>XP_016874853 (OMIM: 602566) PREDICTED: P2X purinocepto (475 aa)
initn: 3177 init1: 3177 opt: 3177 Z-score: 3520.5 bits: 661.1 E(85289): 2.4e-189
Smith-Waterman score: 3177; 99.6% identity (100.0% similar) in 450 aa overlap (146-595:26-475)
120 130 140 150 160 170
pF1KE1 QRLCPEYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVHEGNQKTCEVSAWCPIEAVEE
:::::::::.::::::::::::::::::::
XP_016 MMSLLENVLSAVLSHLWFYDALTPIGIQTGRCVVYEGNQKTCEVSAWCPIEAVEE
10 20 30 40 50
180 190 200 210 220 230
pF1KE1 APRPALLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APRPALLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIF
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE1 RETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCHPKYSFRRLDDKTTNVSLYPGYNFRY
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_016 RETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRY
120 130 140 150 160 170
300 310 320 330 340 350
pF1KE1 AKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLI
180 190 200 210 220 230
360 370 380 390 400 410
pF1KE1 DTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQ
240 250 260 270 280 290
420 430 440 450 460 470
pF1KE1 LLGRSLQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGRSLQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPV
300 310 320 330 340 350
480 490 500 510 520 530
pF1KE1 WCQCGSCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WCQCGSCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLA
360 370 380 390 400 410
540 550 560 570 580 590
pF1KE1 LDVDSTNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDVDSTNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
420 430 440 450 460 470
>>XP_016874854 (OMIM: 602566) PREDICTED: P2X purinocepto (475 aa)
initn: 3177 init1: 3177 opt: 3177 Z-score: 3520.5 bits: 661.1 E(85289): 2.4e-189
Smith-Waterman score: 3177; 99.6% identity (100.0% similar) in 450 aa overlap (146-595:26-475)
120 130 140 150 160 170
pF1KE1 QRLCPEYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVHEGNQKTCEVSAWCPIEAVEE
:::::::::.::::::::::::::::::::
XP_016 MMSLLENVLSAVLSHLWFYDALTPIGIQTGRCVVYEGNQKTCEVSAWCPIEAVEE
10 20 30 40 50
180 190 200 210 220 230
pF1KE1 APRPALLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APRPALLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIF
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE1 RETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCHPKYSFRRLDDKTTNVSLYPGYNFRY
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_016 RETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRY
120 130 140 150 160 170
300 310 320 330 340 350
pF1KE1 AKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLI
180 190 200 210 220 230
360 370 380 390 400 410
pF1KE1 DTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQ
240 250 260 270 280 290
420 430 440 450 460 470
pF1KE1 LLGRSLQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGRSLQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPV
300 310 320 330 340 350
480 490 500 510 520 530
pF1KE1 WCQCGSCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WCQCGSCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLA
360 370 380 390 400 410
540 550 560 570 580 590
pF1KE1 LDVDSTNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDVDSTNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
420 430 440 450 460 470
>>XP_016874855 (OMIM: 602566) PREDICTED: P2X purinocepto (344 aa)
initn: 2445 init1: 2445 opt: 2445 Z-score: 2711.5 bits: 510.9 E(85289): 2.7e-144
Smith-Waterman score: 2445; 99.7% identity (100.0% similar) in 344 aa overlap (252-595:1-344)
230 240 250 260 270 280
pF1KE1 QNPQCPIFRLGDIFRETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCHPKYSFRRLDDK
::::::::::::::::::.:::::::::::
XP_016 MGIEIYWDCNLDRWFHHCRPKYSFRRLDDK
10 20 30
290 300 310 320 330 340
pF1KE1 TTNVSLYPGYNFRYAKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTNVSLYPGYNFRYAKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTL
40 50 60 70 80 90
350 360 370 380 390 400
pF1KE1 SYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYV
100 110 120 130 140 150
410 420 430 440 450 460
pF1KE1 SFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQL
160 170 180 190 200 210
470 480 490 500 510 520
pF1KE1 LRKEATPRSRDSPVWCQCGSCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKEATPRSRDSPVWCQCGSCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRH
220 230 240 250 260 270
530 540 550 560 570 580
pF1KE1 VLQFLLLYQEPLLALDVDSTNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLQFLLLYQEPLLALDVDSTNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEF
280 290 300 310 320 330
590
pF1KE1 PKSEGQYSGFKSPY
::::::::::::::
XP_016 PKSEGQYSGFKSPY
340
>>XP_016874856 (OMIM: 602566) PREDICTED: P2X purinocepto (344 aa)
initn: 2445 init1: 2445 opt: 2445 Z-score: 2711.5 bits: 510.9 E(85289): 2.7e-144
Smith-Waterman score: 2445; 99.7% identity (100.0% similar) in 344 aa overlap (252-595:1-344)
230 240 250 260 270 280
pF1KE1 QNPQCPIFRLGDIFRETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCHPKYSFRRLDDK
::::::::::::::::::.:::::::::::
XP_016 MGIEIYWDCNLDRWFHHCRPKYSFRRLDDK
10 20 30
290 300 310 320 330 340
pF1KE1 TTNVSLYPGYNFRYAKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTNVSLYPGYNFRYAKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTL
40 50 60 70 80 90
350 360 370 380 390 400
pF1KE1 SYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYV
100 110 120 130 140 150
410 420 430 440 450 460
pF1KE1 SFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQL
160 170 180 190 200 210
470 480 490 500 510 520
pF1KE1 LRKEATPRSRDSPVWCQCGSCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKEATPRSRDSPVWCQCGSCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRH
220 230 240 250 260 270
530 540 550 560 570 580
pF1KE1 VLQFLLLYQEPLLALDVDSTNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLQFLLLYQEPLLALDVDSTNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEF
280 290 300 310 320 330
590
pF1KE1 PKSEGQYSGFKSPY
::::::::::::::
XP_016 PKSEGQYSGFKSPY
340
>>XP_011536722 (OMIM: 602566) PREDICTED: P2X purinocepto (306 aa)
initn: 2138 init1: 2138 opt: 2138 Z-score: 2372.1 bits: 448.0 E(85289): 2.2e-125
Smith-Waterman score: 2138; 99.3% identity (100.0% similar) in 305 aa overlap (291-595:2-306)
270 280 290 300 310 320
pF1KE1 NLDRWFHHCHPKYSFRRLDDKTTNVSLYPGYNFRYAKYYKENNVEKRTLIKVFGIRFDIL
..::::::::::::::::::::::::::::
XP_011 MWQFRYAKYYKENNVEKRTLIKVFGIRFDIL
10 20 30
330 340 350 360 370 380
pF1KE1 VFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCCQPCVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCCQPCVVN
40 50 60 70 80 90
390 400 410 420 430 440
pF1KE1 EYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLS
100 110 120 130 140 150
450 460 470 480 490 500
pF1KE1 RLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCGSCLPSQLPESHRCLEELCCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCGSCLPSQLPESHRCLEELCCR
160 170 180 190 200 210
510 520 530 540 550 560
pF1KE1 KKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDSTNSRLRHCAYRCYATWRFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDSTNSRLRHCAYRCYATWRFGS
220 230 240 250 260 270
570 580 590
pF1KE1 QDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
:::::::::::::::::::::::::::::::::::
XP_011 QDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
280 290 300
>>NP_002551 (OMIM: 600846) P2X purinoceptor 4 isoform 2 (388 aa)
initn: 1061 init1: 437 opt: 1132 Z-score: 1256.4 bits: 241.9 E(85289): 3e-63
Smith-Waterman score: 1132; 46.4% identity (73.7% similar) in 377 aa overlap (1-368:1-366)
10 20 30 40 50
pF1KE1 MPACCSC--SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVC-FALVSDKLYQRKEPV
: .::. . .:.:.: ... :.: . : .. ...:..:: ...: .: ::. . :
NP_002 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 ISSVHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQG-NSFFVMTNFLKTEGQEQ
.::: :::::.: : : ..:: ..:.:::..: : ::.::::: . : .: :
NP_002 VSSVTTKVKGVA------VTN-TSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQ
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 RLCPEYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVHEGNQKTCEVSAWCPIEAVEEA
:::: : :.:.:: .: : .:.:..:::::. .:. :::::.::::.: ..
NP_002 GLCPEIPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 PRPALLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNIT----CTFHKTQNPQCPIFRLG
:.::.:..:::::.:.:::: .: :.. :::::... : : . .: :::::::
NP_002 PQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 DIFRETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCHPKYSFRRLDDKTTNVSLYPGYN
: ...: .:.:.:..::::::.. ::::::: : :.::::::: . .. .. ::::
NP_002 KIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 FRYAKYYKE-NNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFI
::.::::.. . :.:::::..::::::.::: .:::::: .. ::: :. .:.:.:.
NP_002 FRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLC
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 DFLIDTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRM
:... : : ....:
NP_002 DIIV-LY---CMKKRLYYREKKYKYVEDYEQGLASELDQ
360 370 380
>>NP_001243725 (OMIM: 600846) P2X purinoceptor 4 isoform (404 aa)
initn: 1101 init1: 437 opt: 1070 Z-score: 1187.5 bits: 229.2 E(85289): 2.1e-59
Smith-Waterman score: 1108; 44.8% identity (71.0% similar) in 393 aa overlap (1-368:1-382)
10 20 30 40
pF1KE1 MPACCSC--SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYV--CF-------------
: .::. . .:.:.: ... :.: . : .. ...:..:: :.
NP_001 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGCYHPHLAEVEMESPR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 --ALVSDKLYQRKEPVISSVHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQG-N
..: .: ::. . :.::: :::::.: : : ..:: ..:.:::..: : :
NP_001 RWVFVWEKGYQETDSVVSSVTTKVKGVA------VTN-TSKLGFRIWDVADYVIPAQEEN
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 SFFVMTNFLKTEGQEQRLCPEYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVHEGNQK
:.::::: . : .: : :::: : :.:.:: .: : .:.:..:::::. .:. :
NP_001 SLFVMTNVILTMNQTQGLCPEIPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVK
120 130 140 150 160 170
170 180 190 200 210
pF1KE1 TCEVSAWCPIEAVEEAPRPALLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNIT----C
::::.::::.: ..:.::.:..:::::.:.:::: .: :.. :::::... : :
NP_001 TCEVAAWCPVEDDTHVPQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSC
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 TFHKTQNPQCPIFRLGDIFRETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCHPKYSFR
. .: ::::::: : ...: .:.:.:..::::::.. ::::::: : :.::::
NP_001 IYDAKTDPFCPIFRLGKIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFR
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE1 RLDDKTTNVSLYPGYNFRYAKYYKE-NNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVV
::: . .. .. ::::::.::::.. . :.:::::..::::::.::: .:::::: ..
NP_001 RLDTRDVEHNVSPGYNFRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMI
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE1 YIGSTLSYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPK
::: :. .:.:.:. :... : : ....:
NP_001 NIGSGLALLGMATVLCDIIV-LY---CMKKRLYYREKKYKYVEDYEQGLASELDQ
360 370 380 390 400
400 410 420 430 440 450
pF1KE1 PTLKYVSFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQ
>>NP_001248327 (OMIM: 600846) P2X purinoceptor 4 isoform (341 aa)
initn: 1016 init1: 437 opt: 1067 Z-score: 1185.2 bits: 228.5 E(85289): 2.8e-59
Smith-Waterman score: 1067; 48.1% identity (74.3% similar) in 339 aa overlap (1-330:1-332)
10 20 30 40 50
pF1KE1 MPACCSC--SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVC-FALVSDKLYQRKEPV
: .::. . .:.:.: ... :.: . : .. ...:..:: ...: .: ::. . :
NP_001 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 ISSVHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQG-NSFFVMTNFLKTEGQEQ
.::: :::::.: : : ..:: ..:.:::..: : ::.::::: . : .: :
NP_001 VSSVTTKVKGVA------VTN-TSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQ
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 RLCPEYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVHEGNQKTCEVSAWCPIEAVEEA
:::: : :.:.:: .: : .:.:..:::::. .:. :::::.::::.: ..
NP_001 GLCPEIPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 PRPALLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNIT----CTFHKTQNPQCPIFRLG
:.::.:..:::::.:.:::: .: :.. :::::... : : . .: :::::::
NP_001 PQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 DIFRETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCHPKYSFRRLDDKTTNVSLYPGYN
: ...: .:.:.:..::::::.. ::::::: : :.::::::: . .. .. ::::
NP_001 KIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 FRYAKYYKE-NNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFI
::.::::.. . :.:::::..::::::.::: .:::::
NP_001 FRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDITPEKFLESD
300 310 320 330 340
360 370 380 390 400 410
pF1KE1 DFLIDTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRM
595 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:03:37 2016 done: Sun Nov 6 23:03:39 2016
Total Scan time: 9.230 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]