FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1067, 506 aa 1>>>pF1KE1067 506 - 506 aa - 506 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6363+/-0.000802; mu= 8.1050+/- 0.049 mean_var=130.4557+/-25.877, 0's: 0 Z-trim(112.3): 34 B-trim: 2 in 1/50 Lambda= 0.112290 statistics sampled from 13025 (13051) to 13025 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.401), width: 16 Scan time: 3.860 The best scores are: opt bits E(32554) CCDS1237.1 NOS1AP gene_id:9722|Hs108|chr1 ( 506) 3331 550.7 1.4e-156 CCDS53421.1 NOS1AP gene_id:9722|Hs108|chr1 ( 501) 3284 543.1 2.7e-154 CCDS44267.1 NOS1AP gene_id:9722|Hs108|chr1 ( 211) 1282 218.6 5.4e-57 >>CCDS1237.1 NOS1AP gene_id:9722|Hs108|chr1 (506 aa) initn: 3331 init1: 3331 opt: 3331 Z-score: 2924.8 bits: 550.7 E(32554): 1.4e-156 Smith-Waterman score: 3331; 100.0% identity (100.0% similar) in 506 aa overlap (1-506:1-506) 10 20 30 40 50 60 pF1KE1 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 EFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS 430 440 450 460 470 480 490 500 pF1KE1 QEELPRLLNVLQRQELGDGLDDEIAV :::::::::::::::::::::::::: CCDS12 QEELPRLLNVLQRQELGDGLDDEIAV 490 500 >>CCDS53421.1 NOS1AP gene_id:9722|Hs108|chr1 (501 aa) initn: 2718 init1: 2718 opt: 3284 Z-score: 2883.7 bits: 543.1 E(32554): 2.7e-154 Smith-Waterman score: 3284; 99.0% identity (99.0% similar) in 506 aa overlap (1-506:1-501) 10 20 30 40 50 60 pF1KE1 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 EFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVS :::::::::::::::::::::::::::::: ::::::::::::::::::::::::: CCDS53 EFKAKNIKKKKVSIMVSVDGVKVILKKKKK-----KKEWTWDESKMLVMQDPIYRIFYVS 70 80 90 100 110 130 140 150 160 170 180 pF1KE1 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE1 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE1 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE1 QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KE1 LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG 360 370 380 390 400 410 430 440 450 460 470 480 pF1KE1 RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS 420 430 440 450 460 470 490 500 pF1KE1 QEELPRLLNVLQRQELGDGLDDEIAV :::::::::::::::::::::::::: CCDS53 QEELPRLLNVLQRQELGDGLDDEIAV 480 490 500 >>CCDS44267.1 NOS1AP gene_id:9722|Hs108|chr1 (211 aa) initn: 1282 init1: 1282 opt: 1282 Z-score: 1136.7 bits: 218.6 E(32554): 5.4e-57 Smith-Waterman score: 1282; 100.0% identity (100.0% similar) in 194 aa overlap (313-506:18-211) 290 300 310 320 330 340 pF1KE1 TETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQN :::::::::::::::::::::::::::::: CCDS44 MSLSSLCPVFSAAASSLQVHLLKDQLAAEAAARLEAQARVHQLLLQN 10 20 30 40 350 360 370 380 390 400 pF1KE1 KDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSP 50 60 70 80 90 100 410 420 430 440 450 460 pF1KE1 PLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGI 110 120 130 140 150 160 470 480 490 500 pF1KE1 ASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV :::::::::::::::::::::::::::::::::::::::::::: CCDS44 ASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV 170 180 190 200 210 506 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:31:26 2016 done: Sat Nov 5 19:31:26 2016 Total Scan time: 3.860 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]