Result of FASTA (omim) for
pF1KE1004
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1004, 162 aa
1>>>pF1KE1004 162 - 162 aa - 162 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6476+/-0.000317; mu= 15.6247+/- 0.020
mean_var=60.8821+/-12.181, 0's: 0 Z-trim(115.7): 30 B-trim: 0 in 0/55
Lambda= 0.164373
statistics sampled from 26261 (26291) to 26261 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.308), width: 16
Scan time: 5.170
The best scores are: opt bits E(85289)
XP_006718489 (OMIM: 613867) PREDICTED: HRAS-like s ( 162) 1068 261.2 5.4e-70
NP_009000 (OMIM: 613867) HRAS-like suppressor 3 [H ( 162) 1068 261.2 5.4e-70
NP_001121675 (OMIM: 613867) HRAS-like suppressor 3 ( 162) 1068 261.2 5.4e-70
XP_011543043 (OMIM: 613867) PREDICTED: HRAS-like s ( 177) 1039 254.3 6.8e-68
NP_060348 (OMIM: 613866) HRAS-like suppressor 2 [H ( 162) 728 180.5 1e-45
XP_011543422 (OMIM: 613866) PREDICTED: HRAS-like s ( 195) 728 180.6 1.2e-45
NP_004576 (OMIM: 605092) retinoic acid receptor re ( 164) 543 136.7 1.6e-32
XP_016862412 (OMIM: 606487) PREDICTED: phospholipi ( 168) 487 123.4 1.7e-28
NP_065119 (OMIM: 606487) phospholipid-metabolizing ( 273) 487 123.6 2.4e-28
XP_011511337 (OMIM: 606487) PREDICTED: phospholipi ( 339) 465 118.4 1.1e-26
XP_011511336 (OMIM: 606487) PREDICTED: phospholipi ( 342) 465 118.4 1.1e-26
XP_016872661 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 159) 455 115.8 3.1e-26
XP_011543055 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 159) 455 115.8 3.1e-26
XP_011543053 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 268) 455 116.0 4.6e-26
NP_001140201 (OMIM: 611474) Ca(2+)-independent N-a ( 269) 455 116.0 4.6e-26
NP_473449 (OMIM: 611474) Ca(2+)-independent N-acyl ( 279) 455 116.0 4.7e-26
NP_001140200 (OMIM: 611474) Ca(2+)-independent N-a ( 253) 353 91.8 8.3e-19
XP_011543054 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 167) 288 76.2 2.7e-14
>>XP_006718489 (OMIM: 613867) PREDICTED: HRAS-like suppr (162 aa)
initn: 1068 init1: 1068 opt: 1068 Z-score: 1377.6 bits: 261.2 E(85289): 5.4e-70
Smith-Waterman score: 1068; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)
10 20 30 40 50 60
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
70 80 90 100 110 120
130 140 150 160
pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
::::::::::::::::::::::::::::::::::::::::::
XP_006 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160
>>NP_009000 (OMIM: 613867) HRAS-like suppressor 3 [Homo (162 aa)
initn: 1068 init1: 1068 opt: 1068 Z-score: 1377.6 bits: 261.2 E(85289): 5.4e-70
Smith-Waterman score: 1068; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)
10 20 30 40 50 60
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
70 80 90 100 110 120
130 140 150 160
pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
::::::::::::::::::::::::::::::::::::::::::
NP_009 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160
>>NP_001121675 (OMIM: 613867) HRAS-like suppressor 3 [Ho (162 aa)
initn: 1068 init1: 1068 opt: 1068 Z-score: 1377.6 bits: 261.2 E(85289): 5.4e-70
Smith-Waterman score: 1068; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)
10 20 30 40 50 60
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
70 80 90 100 110 120
130 140 150 160
pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
::::::::::::::::::::::::::::::::::::::::::
NP_001 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160
>>XP_011543043 (OMIM: 613867) PREDICTED: HRAS-like suppr (177 aa)
initn: 1039 init1: 1039 opt: 1039 Z-score: 1339.9 bits: 254.3 E(85289): 6.8e-68
Smith-Waterman score: 1039; 100.0% identity (100.0% similar) in 158 aa overlap (5-162:20-177)
10 20 30 40
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGA
:::::::::::::::::::::::::::::::::::::::::
XP_011 MKTQRSSWCQLLLHRIGQRIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 GAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 YKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160 170
>>NP_060348 (OMIM: 613866) HRAS-like suppressor 2 [Homo (162 aa)
initn: 729 init1: 709 opt: 728 Z-score: 941.9 bits: 180.5 E(85289): 1e-45
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:6-162)
10 20 30 40 50 60
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
:.:. :::::: : : :::::::::::::::: ::.::::::::.::::.::::
NP_060 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
::::: :::.:.:.:::::::.:.::: .::..:::::::::. :.:::.:::::::.:
NP_060 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
70 80 90 100 110 120
130 140 150 160
pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
::::.::::: .. ...::. ::: ::.:....:.::..:
NP_060 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
130 140 150 160
>>XP_011543422 (OMIM: 613866) PREDICTED: HRAS-like suppr (195 aa)
initn: 729 init1: 709 opt: 728 Z-score: 940.8 bits: 180.6 E(85289): 1.2e-45
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:39-195)
10 20 30
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVH
:.:. :::::: : : :::::::::::::
XP_011 RVFQFWLQSICIPTLKLFVCLFVYSLKRARPRPRLGDLIEISRFGYAHWAIYVGDGYVVH
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE1 LAPPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQR
::: ::.::::::::.::::.::::::::: :::.:.:.:::::::.:.::: .::..:
XP_011 LAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 AEELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFS
::::::::. :.:::.:::::::.:::::.::::: .. ...::. ::: ::.:....
XP_011 AEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLA
130 140 150 160 170 180
160
pF1KE1 RNKRQKQ
:.::..:
XP_011 RSKRERQ
190
>>NP_004576 (OMIM: 605092) retinoic acid receptor respon (164 aa)
initn: 514 init1: 514 opt: 543 Z-score: 704.7 bits: 136.7 E(85289): 1.6e-32
Smith-Waterman score: 543; 51.2% identity (77.8% similar) in 162 aa overlap (1-162:1-161)
10 20 30 40 50 60
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
: .: :::::::::::: :.:::.:.:::::.::::::: :::..::.:.:...: :
NP_004 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
:.: : ::.:. :.:::. : .:.: : ::. :.:.:::.. :...:.::::::..:
NP_004 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL
70 80 90 100 110 120
130 140 150 160
pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
::: .: ::. . . ..:: .:. . . : :. . ::.
NP_004 RYGKSRCKQVEKAKVEVGVA-TALGILVVAGCSFAIRRYQKKATA
130 140 150 160
>>XP_016862412 (OMIM: 606487) PREDICTED: phospholipid-me (168 aa)
initn: 454 init1: 285 opt: 487 Z-score: 632.8 bits: 123.4 E(85289): 1.7e-28
Smith-Waterman score: 487; 46.8% identity (79.2% similar) in 154 aa overlap (8-161:15-166)
10 20 30 40 50
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSA
: ::::::.::: :.:::.:.:::::...:: . . :. .:. :.
XP_016 MAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIP-ASFTSAKSV
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 LTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENC
...::.:: .:: ::.:.: :..:::.:. : ::: .::.:.: ..:::: :.: .::
XP_016 FSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNC
60 70 80 90 100 110
120 130 140 150 160
pF1KE1 EHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
::::. :::: . :.:. .: .. . .....:..: .: ...: :
XP_016 EHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLG-LFPKGQRAKYY
120 130 140 150 160
>>NP_065119 (OMIM: 606487) phospholipid-metabolizing enz (273 aa)
initn: 454 init1: 285 opt: 487 Z-score: 629.9 bits: 123.6 E(85289): 2.4e-28
Smith-Waterman score: 487; 46.8% identity (79.2% similar) in 154 aa overlap (8-161:120-271)
10 20 30
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLA
: ::::::.::: :.:::.:.:::::...:
NP_065 TQLPPGARRRPRLESEMAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIA
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE1 PPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAE
: . . :. .:. :....::.:: .:: ::.:.: :..:::.:. : ::: .::.:.:
NP_065 PVDGIP-ASFTSAKSVFSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSE
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE1 ELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRN
..:::: :.: .::::::. :::: . :.:. .: .. . .....:..: .: ..
NP_065 FVIGQEVAYNLLVNNCEHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLG-LFPKG
210 220 230 240 250 260
160
pF1KE1 KRQKQ
.: :
NP_065 QRAKYY
270
>>XP_011511337 (OMIM: 606487) PREDICTED: phospholipid-me (339 aa)
initn: 454 init1: 285 opt: 465 Z-score: 600.4 bits: 118.4 E(85289): 1.1e-26
Smith-Waterman score: 465; 53.7% identity (82.1% similar) in 123 aa overlap (8-130:120-241)
10 20 30
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLA
: ::::::.::: :.:::.:.:::::...:
XP_011 TQLPPGARRRPRLESEMAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIA
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE1 PPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAE
: . . :. .:. :....::.:: .:: ::.:.: :..:::.:. : ::: .::.:.:
XP_011 PVDGIP-ASFTSAKSVFSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSE
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE1 ELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRN
..:::: :.: .::::::. :::: . :.:.
XP_011 FVIGQEVAYNLLVNNCEHFVTLLRYGEGVSEQIIQLKDSKPINKWQNQNSKENGLPLGLC
210 220 230 240 250 260
160
pF1KE1 KRQKQ
XP_011 TFDSLMVPTEKCALNHKYETGHFGGYVSVSIFIFSNRRLRLNHSSNNVNISNSPKANSTW
270 280 290 300 310 320
162 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:21:23 2016 done: Sat Nov 5 13:21:24 2016
Total Scan time: 5.170 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]