Result of FASTA (omim) for
pF1KE0965
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0965, 509 aa
1>>>pF1KE0965 509 - 509 aa - 509 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.0564+/-0.000686; mu= -14.5473+/- 0.040
mean_var=869.1907+/-200.490, 0's: 0 Z-trim(113.9): 126 B-trim: 0 in 0/54
Lambda= 0.043503
statistics sampled from 23348 (23438) to 23348 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.275), width: 16
Scan time: 8.120
The best scores are: opt bits E(85289)
NP_001096 (OMIM: 102576,135100) activin receptor t ( 509) 3490 235.9 2.1e-61
NP_001104537 (OMIM: 102576,135100) activin recepto ( 509) 3490 235.9 2.1e-61
XP_011510408 (OMIM: 102576,135100) PREDICTED: acti ( 509) 3490 235.9 2.1e-61
XP_011510409 (OMIM: 102576,135100) PREDICTED: acti ( 509) 3490 235.9 2.1e-61
XP_005246997 (OMIM: 102576,135100) PREDICTED: acti ( 509) 3490 235.9 2.1e-61
XP_006712888 (OMIM: 102576,135100) PREDICTED: acti ( 509) 3490 235.9 2.1e-61
XP_011510410 (OMIM: 102576,135100) PREDICTED: acti ( 509) 3490 235.9 2.1e-61
XP_005246996 (OMIM: 102576,135100) PREDICTED: acti ( 509) 3490 235.9 2.1e-61
NP_001070869 (OMIM: 600376,601284) serine/threonin ( 503) 1985 141.4 5.7e-33
NP_000011 (OMIM: 600376,601284) serine/threonine-p ( 503) 1985 141.4 5.7e-33
XP_005269292 (OMIM: 600376,601284) PREDICTED: seri ( 503) 1985 141.4 5.7e-33
XP_011537310 (OMIM: 600376,601284) PREDICTED: seri ( 413) 1617 118.2 4.6e-26
NP_001243723 (OMIM: 112600,603248,609441,616849) b ( 502) 1600 117.3 1.1e-25
NP_001194 (OMIM: 112600,603248,609441,616849) bone ( 502) 1600 117.3 1.1e-25
NP_001243721 (OMIM: 112600,603248,609441,616849) b ( 502) 1600 117.3 1.1e-25
XP_011530503 (OMIM: 112600,603248,609441,616849) P ( 502) 1600 117.3 1.1e-25
XP_016864048 (OMIM: 112600,603248,609441,616849) P ( 502) 1600 117.3 1.1e-25
XP_016864049 (OMIM: 112600,603248,609441,616849) P ( 502) 1600 117.3 1.1e-25
XP_016864047 (OMIM: 112600,603248,609441,616849) P ( 502) 1600 117.3 1.1e-25
XP_016864050 (OMIM: 112600,603248,609441,616849) P ( 502) 1600 117.3 1.1e-25
NP_001243722 (OMIM: 112600,603248,609441,616849) b ( 532) 1600 117.3 1.1e-25
XP_011538406 (OMIM: 174900,601299,610069) PREDICTE ( 532) 1580 116.1 2.6e-25
XP_011538405 (OMIM: 174900,601299,610069) PREDICTE ( 532) 1580 116.1 2.6e-25
NP_004320 (OMIM: 174900,601299,610069) bone morpho ( 532) 1580 116.1 2.6e-25
NP_660302 (OMIM: 608981) activin receptor type-1C ( 493) 1547 113.9 1.1e-24
NP_001293139 (OMIM: 132800,190181) TGF-beta recept ( 507) 1542 113.7 1.3e-24
XP_011517250 (OMIM: 132800,190181) PREDICTED: TGF- ( 438) 1522 112.3 3e-24
XP_016870552 (OMIM: 132800,190181) PREDICTED: TGF- ( 438) 1522 112.3 3e-24
NP_004293 (OMIM: 601300) activin receptor type-1B ( 505) 1519 112.2 3.7e-24
NP_004603 (OMIM: 132800,190181) TGF-beta receptor ( 503) 1511 111.7 5.2e-24
NP_001104501 (OMIM: 608981) activin receptor type- ( 443) 1504 111.2 6.6e-24
XP_011517251 (OMIM: 132800,190181) PREDICTED: TGF- ( 434) 1496 110.7 9.2e-24
NP_064732 (OMIM: 601300) activin receptor type-1B ( 453) 1488 110.2 1.3e-23
XP_011517252 (OMIM: 132800,190181) PREDICTED: TGF- ( 357) 1415 105.4 2.8e-22
NP_001124388 (OMIM: 132800,190181) TGF-beta recept ( 426) 1415 105.6 3.1e-22
NP_001104502 (OMIM: 608981) activin receptor type- ( 413) 1365 102.4 2.7e-21
XP_016875690 (OMIM: 601300) PREDICTED: activin rec ( 381) 1004 79.7 1.7e-14
XP_016875689 (OMIM: 601300) PREDICTED: activin rec ( 494) 973 77.9 7.5e-14
XP_016875688 (OMIM: 601300) PREDICTED: activin rec ( 494) 973 77.9 7.5e-14
NP_064733 (OMIM: 601300) activin receptor type-1B ( 546) 973 78.0 7.9e-14
NP_001104503 (OMIM: 608981) activin receptor type- ( 336) 962 77.0 9.9e-14
NP_001265509 (OMIM: 102581) activin receptor type- ( 405) 740 63.2 1.7e-09
NP_001607 (OMIM: 102581) activin receptor type-2A ( 513) 740 63.3 1.9e-09
NP_001265508 (OMIM: 102581) activin receptor type- ( 513) 740 63.3 1.9e-09
XP_016863005 (OMIM: 602730,613751) PREDICTED: acti ( 511) 731 62.8 2.8e-09
NP_001097 (OMIM: 602730,613751) activin receptor t ( 512) 731 62.8 2.8e-09
XP_016863004 (OMIM: 602730,613751) PREDICTED: acti ( 518) 731 62.8 2.9e-09
XP_016863003 (OMIM: 602730,613751) PREDICTED: acti ( 526) 731 62.8 2.9e-09
XP_005265640 (OMIM: 602730,613751) PREDICTED: acti ( 533) 731 62.8 2.9e-09
XP_016862595 (OMIM: 133239,190182,610168,614331) P ( 532) 727 62.5 3.5e-09
>>NP_001096 (OMIM: 102576,135100) activin receptor type- (509 aa)
initn: 3490 init1: 3490 opt: 3490 Z-score: 1223.3 bits: 235.9 E(85289): 2.1e-61
Smith-Waterman score: 3490; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KE0 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
430 440 450 460 470 480
490 500
pF1KE0 NPSARLTALRIKKTLTKIDNSLDKLKTDC
:::::::::::::::::::::::::::::
NP_001 NPSARLTALRIKKTLTKIDNSLDKLKTDC
490 500
>>NP_001104537 (OMIM: 102576,135100) activin receptor ty (509 aa)
initn: 3490 init1: 3490 opt: 3490 Z-score: 1223.3 bits: 235.9 E(85289): 2.1e-61
Smith-Waterman score: 3490; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KE0 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
430 440 450 460 470 480
490 500
pF1KE0 NPSARLTALRIKKTLTKIDNSLDKLKTDC
:::::::::::::::::::::::::::::
NP_001 NPSARLTALRIKKTLTKIDNSLDKLKTDC
490 500
>>XP_011510408 (OMIM: 102576,135100) PREDICTED: activin (509 aa)
initn: 3490 init1: 3490 opt: 3490 Z-score: 1223.3 bits: 235.9 E(85289): 2.1e-61
Smith-Waterman score: 3490; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KE0 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
430 440 450 460 470 480
490 500
pF1KE0 NPSARLTALRIKKTLTKIDNSLDKLKTDC
:::::::::::::::::::::::::::::
XP_011 NPSARLTALRIKKTLTKIDNSLDKLKTDC
490 500
>>XP_011510409 (OMIM: 102576,135100) PREDICTED: activin (509 aa)
initn: 3490 init1: 3490 opt: 3490 Z-score: 1223.3 bits: 235.9 E(85289): 2.1e-61
Smith-Waterman score: 3490; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KE0 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
430 440 450 460 470 480
490 500
pF1KE0 NPSARLTALRIKKTLTKIDNSLDKLKTDC
:::::::::::::::::::::::::::::
XP_011 NPSARLTALRIKKTLTKIDNSLDKLKTDC
490 500
>>XP_005246997 (OMIM: 102576,135100) PREDICTED: activin (509 aa)
initn: 3490 init1: 3490 opt: 3490 Z-score: 1223.3 bits: 235.9 E(85289): 2.1e-61
Smith-Waterman score: 3490; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KE0 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
430 440 450 460 470 480
490 500
pF1KE0 NPSARLTALRIKKTLTKIDNSLDKLKTDC
:::::::::::::::::::::::::::::
XP_005 NPSARLTALRIKKTLTKIDNSLDKLKTDC
490 500
>>XP_006712888 (OMIM: 102576,135100) PREDICTED: activin (509 aa)
initn: 3490 init1: 3490 opt: 3490 Z-score: 1223.3 bits: 235.9 E(85289): 2.1e-61
Smith-Waterman score: 3490; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KE0 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
430 440 450 460 470 480
490 500
pF1KE0 NPSARLTALRIKKTLTKIDNSLDKLKTDC
:::::::::::::::::::::::::::::
XP_006 NPSARLTALRIKKTLTKIDNSLDKLKTDC
490 500
>>XP_011510410 (OMIM: 102576,135100) PREDICTED: activin (509 aa)
initn: 3490 init1: 3490 opt: 3490 Z-score: 1223.3 bits: 235.9 E(85289): 2.1e-61
Smith-Waterman score: 3490; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KE0 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
430 440 450 460 470 480
490 500
pF1KE0 NPSARLTALRIKKTLTKIDNSLDKLKTDC
:::::::::::::::::::::::::::::
XP_011 NPSARLTALRIKKTLTKIDNSLDKLKTDC
490 500
>>XP_005246996 (OMIM: 102576,135100) PREDICTED: activin (509 aa)
initn: 3490 init1: 3490 opt: 3490 Z-score: 1223.3 bits: 235.9 E(85289): 2.1e-61
Smith-Waterman score: 3490; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KE0 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
430 440 450 460 470 480
490 500
pF1KE0 NPSARLTALRIKKTLTKIDNSLDKLKTDC
:::::::::::::::::::::::::::::
XP_005 NPSARLTALRIKKTLTKIDNSLDKLKTDC
490 500
>>NP_001070869 (OMIM: 600376,601284) serine/threonine-pr (503 aa)
initn: 1898 init1: 1832 opt: 1985 Z-score: 712.9 bits: 141.4 E(85289): 5.7e-33
Smith-Waterman score: 1985; 61.1% identity (79.2% similar) in 501 aa overlap (10-506:11-500)
10 20 30 40 50
pF1KE0 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSI
.....:: . . . ::. .: : :.::. : . :.: : :
NP_001 MTLGSPRKGLLMLLMALVTQG-DPVKPSRGP-LVTCTCESPHCKGPT-CRGAWCTVVLVR
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 NDGFHVYQ-KGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLP-TKGKSF-PG
..: : . .:: ..... :. :. ::.. ::.:.. : :. : ::
NP_001 EEGRHPQEHRGCGNLHRE---LCRGRPTEFVNHYCCDSHLCNHNVSLVLEATQPPSEQPG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TQNFHLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLI-TTNV
:.. ...::. :. . :.: ::: :: ::. : : .. ...
NP_001 TDG---QLALILGPVLALLALVA--LGVLGLWHVRRRQEKQRGLHSELGESSLILKASEQ
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 GDSTLADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVK
::: :.:::: .::.:::::::::::::::::..:.:::::::::::::: :.::.::::
NP_001 GDSMLGDLLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGLWHGESVAVK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 IFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYL
:::::::.:::::::.::::.:::.:::::::::::::.::::::::::::: :::::.:
NP_001 IFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE0 QLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADL
: ::. ::...: : ::::::.:::::::::::::::.::.:.:::.: :::::::
NP_001 QRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDFKSRNVLVKSNLQCCIADL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE0 GLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVA
::::::::... ::.::::::::::::::::::: :..:::.::: .:::::::::::.:
NP_001 GLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDEQIRTDCFESYKWTDIWAFGLVLWEIA
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE0 RRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMK
:: . :::::::.::::::::::::::::.:::::::: :.:::: .::.:..::..:.
NP_001 RRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMR
410 420 430 440 450 460
480 490 500
pF1KE0 ECWYQNPSARLTALRIKKTLTKIDNSLDKLKTDC
:::: ::::::::::::::: ::.:: .: :
NP_001 ECWYPNPSARLTALRIKKTLQKISNSPEKPKVIQ
470 480 490 500
>>NP_000011 (OMIM: 600376,601284) serine/threonine-prote (503 aa)
initn: 1898 init1: 1832 opt: 1985 Z-score: 712.9 bits: 141.4 E(85289): 5.7e-33
Smith-Waterman score: 1985; 61.1% identity (79.2% similar) in 501 aa overlap (10-506:11-500)
10 20 30 40 50
pF1KE0 MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSI
.....:: . . . ::. .: : :.::. : . :.: : :
NP_000 MTLGSPRKGLLMLLMALVTQG-DPVKPSRGP-LVTCTCESPHCKGPT-CRGAWCTVVLVR
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 NDGFHVYQ-KGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLP-TKGKSF-PG
..: : . .:: ..... :. :. ::.. ::.:.. : :. : ::
NP_000 EEGRHPQEHRGCGNLHRE---LCRGRPTEFVNHYCCDSHLCNHNVSLVLEATQPPSEQPG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TQNFHLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLI-TTNV
:.. ...::. :. . :.: ::: :: ::. : : .. ...
NP_000 TDG---QLALILGPVLALLALVA--LGVLGLWHVRRRQEKQRGLHSELGESSLILKASEQ
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 GDSTLADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVK
::: :.:::: .::.:::::::::::::::::..:.:::::::::::::: :.::.::::
NP_000 GDSMLGDLLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGLWHGESVAVK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 IFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYL
:::::::.:::::::.::::.:::.:::::::::::::.::::::::::::: :::::.:
NP_000 IFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE0 QLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADL
: ::. ::...: : ::::::.:::::::::::::::.::.:.:::.: :::::::
NP_000 QRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDFKSRNVLVKSNLQCCIADL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE0 GLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVA
::::::::... ::.::::::::::::::::::: :..:::.::: .:::::::::::.:
NP_000 GLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDEQIRTDCFESYKWTDIWAFGLVLWEIA
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE0 RRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMK
:: . :::::::.::::::::::::::::.:::::::: :.:::: .::.:..::..:.
NP_000 RRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMR
410 420 430 440 450 460
480 490 500
pF1KE0 ECWYQNPSARLTALRIKKTLTKIDNSLDKLKTDC
:::: ::::::::::::::: ::.:: .: :
NP_000 ECWYPNPSARLTALRIKKTLQKISNSPEKPKVIQ
470 480 490 500
509 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:53:51 2016 done: Sat Nov 5 18:53:53 2016
Total Scan time: 8.120 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]