Result of FASTA (omim) for
pF1KE0840
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0840, 345 aa
1>>>pF1KE0840 345 - 345 aa - 345 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4873+/-0.000497; mu= 21.3439+/- 0.031
mean_var=136.7633+/-40.387, 0's: 0 Z-trim(108.9): 588 B-trim: 1064 in 1/50
Lambda= 0.109670
statistics sampled from 16285 (17068) to 16285 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.55), E-opt: 0.2 (0.2), width: 16
Scan time: 6.320
The best scores are: opt bits E(85289)
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 2317 379.1 7.8e-105
NP_444508 (OMIM: 606927) trace amine-associated re ( 342) 1880 309.9 5e-84
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 1690 279.9 5.7e-75
NP_003958 (OMIM: 607405) trace amine-associated re ( 337) 1025 174.6 2.6e-43
NP_612200 (OMIM: 609333) trace amine-associated re ( 339) 941 161.4 2.7e-39
NP_001028252 (OMIM: 604849) trace amine-associated ( 351) 894 154.0 4.7e-37
NP_055441 (OMIM: 604849) trace amine-associated re ( 306) 861 148.6 1.6e-35
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324) 473 87.3 5.1e-17
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317) 472 87.1 5.6e-17
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 468 86.5 8.6e-17
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342) 468 86.5 9e-17
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370) 468 86.6 9.4e-17
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372) 468 86.6 9.4e-17
XP_006716356 (OMIM: 104221) PREDICTED: alpha-1A ad ( 429) 468 86.7 1e-16
NP_150645 (OMIM: 104221) alpha-1A adrenergic recep ( 429) 468 86.7 1e-16
NP_150647 (OMIM: 104221) alpha-1A adrenergic recep ( 455) 468 86.7 1e-16
NP_000671 (OMIM: 104221) alpha-1A adrenergic recep ( 466) 468 86.8 1e-16
XP_016868583 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 468 86.8 1.1e-16
NP_150646 (OMIM: 104221) alpha-1A adrenergic recep ( 475) 468 86.8 1.1e-16
XP_016868584 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 468 86.8 1.1e-16
XP_006716355 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 468 86.8 1.1e-16
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 429 80.4 6.6e-15
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 429 80.4 6.7e-15
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 429 80.5 7e-15
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 429 80.5 7.2e-15
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 429 80.5 7.2e-15
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 429 80.5 7.2e-15
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 429 80.5 7.2e-15
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 429 80.5 7.2e-15
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412) 427 80.2 8.9e-15
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412) 427 80.2 8.9e-15
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412) 427 80.2 8.9e-15
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412) 427 80.2 8.9e-15
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412) 427 80.2 8.9e-15
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360) 418 78.7 2.2e-14
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378) 418 78.7 2.3e-14
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387) 418 78.7 2.3e-14
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388) 418 78.7 2.3e-14
NP_001273339 (OMIM: 602164) 5-hydroxytryptamine re ( 411) 418 78.8 2.4e-14
NP_001035263 (OMIM: 602164) 5-hydroxytryptamine re ( 428) 418 78.8 2.4e-14
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413) 414 78.1 3.7e-14
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465) 403 76.5 1.3e-13
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 400 75.9 1.7e-13
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450) 397 75.5 2.5e-13
NP_000855 (OMIM: 182133) 5-hydroxytryptamine recep ( 377) 395 75.1 2.8e-13
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462) 390 74.4 5.4e-13
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328) 386 73.5 7.1e-13
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331) 386 73.5 7.1e-13
XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B ad ( 366) 386 73.6 7.5e-13
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 387 74.0 7.7e-13
>>NP_778237 (OMIM: 608923) trace amine-associated recept (345 aa)
initn: 2317 init1: 2317 opt: 2317 Z-score: 2003.1 bits: 379.1 E(85289): 7.8e-105
Smith-Waterman score: 2317; 100.0% identity (100.0% similar) in 345 aa overlap (1-345:1-345)
10 20 30 40 50 60
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
250 260 270 280 290 300
310 320 330 340
pF1KE0 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
:::::::::::::::::::::::::::::::::::::::::::::
NP_778 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
310 320 330 340
>>NP_444508 (OMIM: 606927) trace amine-associated recept (342 aa)
initn: 1890 init1: 1870 opt: 1880 Z-score: 1629.5 bits: 309.9 E(85289): 5e-84
Smith-Waterman score: 1880; 79.6% identity (92.7% similar) in 343 aa overlap (1-343:1-342)
10 20 30 40 50 60
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
:.:: : : ::::: .:::::.. :.::::::::: .:.::..:::::::::: :.:::
NP_444 MTSNFSQPV-VQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHF
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
::::::::::.::::::::::::::: :::::::::::::: .:::.:.::::::::::.
NP_444 KQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
.::::: :::::.::::::: :::::::::::::::::::: :::::::::: :::::::
NP_444 LHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
.::::.:::: .:.:.::: ::: :::::..:::::..:::.:..:: :::.:.::.::
NP_444 VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
:::::: :::.:::::::::::::.::.::::::..: ::::::::.::: ::::::: :
NP_444 SSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSA
240 250 260 270 280 290
310 320 330 340
pF1KE0 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
:::::::::::::::::::::::.:..:.::: ::.:..:: :
NP_444 YYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
300 310 320 330 340
>>NP_778227 (OMIM: 608282) trace amine-associated recept (348 aa)
initn: 1730 init1: 1682 opt: 1690 Z-score: 1467.0 bits: 279.9 E(85289): 5.7e-75
Smith-Waterman score: 1690; 69.0% identity (89.0% similar) in 345 aa overlap (1-345:1-345)
10 20 30 40 50 60
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
: .: : ::.::: ::: ::.: :.::: : ::: :.:::::::.::::::::.::::
NP_778 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
::::.:::::.:::::::::::::::::: ::.:::::::: :.: :::: :..::..::
NP_778 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
:::: ::.::::::::::.:::::::::::::: .::.. . :: ..::::. ..:.:::
NP_778 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
::.:.::::. .:::::: :: ::::. :...:..:::::..::.:::.:.:...:
NP_778 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
:::::: :::.::::::::::....::..::::: .:..:::.:.:::: .::: ::.
NP_778 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV
250 260 270 280 290 300
310 320 330 340
pF1KE0 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
::::::::::::.:: :: ::::.::.:.::...:.: :::::..
NP_778 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
310 320 330 340
>>NP_003958 (OMIM: 607405) trace amine-associated recept (337 aa)
initn: 1037 init1: 699 opt: 1025 Z-score: 898.4 bits: 174.6 E(85289): 2.6e-43
Smith-Waterman score: 1025; 43.8% identity (74.9% similar) in 331 aa overlap (13-343:16-337)
10 20 30 40 50
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISI
.:: .::::: . . : ....:.. . : .. :.::..: ...
NP_003 MRAVFIQGAEEHPAAFCY-QVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCY
.:: ::.:::::. ::: ::...:. :.:.: .:.:::::.:: .: .:: :. ::
NP_003 SYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGL
.:.::::::::::. :. :::.::.:::: :. : ..: .: :.. .:: : . :
NP_003 TSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 EELSDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSK
. . . :.:.:: ..:. : .: ::.: .::: :: .::.:: :::..: .: ::
NP_003 SQWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQI-TTLSK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 TESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICC
. ... :..:::::::::..: ... :::..::...:... :::: ...:
NP_003 SLAGA-------AKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFI
240 250 260 270 280 290
300 310 320 330 340
pF1KE0 WCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
: ::.::: ::.::.. : :::::.:. .. .:.. .. :..:..:
NP_003 WFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE
300 310 320 330
>>NP_612200 (OMIM: 609333) trace amine-associated recept (339 aa)
initn: 932 init1: 506 opt: 941 Z-score: 826.6 bits: 161.4 E(85289): 2.7e-39
Smith-Waterman score: 941; 41.1% identity (72.1% similar) in 333 aa overlap (13-343:4-336)
10 20 30 40 50 60
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
.:. .: :::: .: :. :: .. . . .. :::.:..:: ::
NP_612 MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHF
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
::::.:::.:. :.: .:::.: :::.::::..: :::::. :: .:: :. . .:.
NP_612 KQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
::: ::::::: :: ::: : .:... : . : .:: .: ... .... . : ::.
NP_612 FHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEI
120 130 140 150 160 170
190 200 210 220 230
pF1KE0 S-DALNCIGGCQTVVNQ-NWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKT
..: :::.. .. . ::: . ::.:: ::. .: :.:.:..::. : ....:
NP_612 YYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 ESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCW
. . : .. .::::.::::... .:.: : :. : ...: :. .: : . .. :
NP_612 QIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIW
240 250 260 270 280 290
300 310 320 330 340
pF1KE0 CAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
.: ::..::..::.::::::::.:... :......:. .:: :
NP_612 FGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
300 310 320 330
>>NP_001028252 (OMIM: 604849) trace amine-associated rec (351 aa)
initn: 867 init1: 500 opt: 894 Z-score: 786.3 bits: 154.0 E(85289): 4.7e-37
Smith-Waterman score: 894; 39.6% identity (70.1% similar) in 321 aa overlap (14-333:25-337)
10 20 30 40
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFG
: : :: . : : :: .: .. . ...::
NP_001 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 NLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHT
:: ..::: .:::::.:::::. :.: .:::.: :.::.::.:.::.::::: .:: ..
NP_001 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 CCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFY
:. . .:.:::: ..:::. :. ::.: ::.:. : . . : .: .. .: .
NP_001 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 TGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLS-FFIPTFIMIILYGNIFLVARRQA
. .: ::.: . . : ..: .. :. : : :.. :: : .:. .::.:: :.:..:
NP_001 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 KKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFIT
. :.: :. . .: ....:::::::... .:.. :.: . :.: :..: :
NP_001 HAINNL-------RENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFST
250 260 270 280 290
290 300 310 320 330 340
pF1KE0 PACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
:. ... : .:.::. :::::..::::::.:.: :. :.....
NP_001 PVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
300 310 320 330 340 350
>>NP_055441 (OMIM: 604849) trace amine-associated recept (306 aa)
initn: 833 init1: 466 opt: 861 Z-score: 758.6 bits: 148.6 E(85289): 1.6e-35
Smith-Waterman score: 861; 40.4% identity (72.4% similar) in 297 aa overlap (39-333:4-292)
10 20 30 40 50 60
pF1KE0 VAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAV-LAVFGNLLVMISILHFKQLHSPT
: :.. ...:::: ..::: .:::::.::
NP_055 MYSFMAGSIFITIFGNLAMIISISYFKQLHTPT
10 20 30
70 80 90 100 110 120
pF1KE0 NFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFIS
:::. :.: .:::.: :.::.::.:.::.::::: .:: .. :. . .:.:::: ..
NP_055 NFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 IDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCI
:::. :. ::.: ::.:. : . . : .: .. .: .. .: ::.: . . :
NP_055 IDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 GGCQTVVNQNWVLTDFLS-FFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYK
..: .. :. : : :.. :: : .:. .::.:: :.:..:. :.: :. .
NP_055 SSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNL-------RENQN
160 170 180 190 200
250 260 270 280 290 300
pF1KE0 ARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAM
.: ....:::::::... .:.. :.: . :.: :..: ::. ... : .:.::.
NP_055 NQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTC
210 220 230 240 250 260
310 320 330 340
pF1KE0 NPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
:::::..::::::.:.: :. :.....
NP_055 NPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
270 280 290 300
>>XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A adrene (324 aa)
initn: 417 init1: 327 opt: 473 Z-score: 426.6 bits: 87.3 E(85289): 5.1e-17
Smith-Waterman score: 478; 32.6% identity (60.8% similar) in 291 aa overlap (16-274:8-288)
10 20 30 40 50
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVK--IPFSPGSRVILYIVFGFGAVLAVFGNLLVMISIL
:. ...:.. : . .. ..: ...: ...:.::.::..:.
XP_011 MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVA
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 HFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYS
..::: :.. ...:: ::.:. ::.::: . : . : ::: ::.. . :: : .
XP_011 CHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYS-GAVFYTGVYDDGL
:.. ::.:::::::.:. :: ::: : . . . : : :. : : .: :
XP_011 SIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF-------GW
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 EELSDALNCIGGCQTVVNQNWVLTDFL-SFFIPTFIMIILYGNIFLVARRQAKKIENTGS
.. . . : :: . ..:: . : ::..: :....: ...::.:... .. .:
XP_011 RQPAPEDETI--CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLK-SGL
170 180 190 200 210 220
240 250 260
pF1KE0 KTESS-SESYKARVAR---------------------------RERKAAKTLGVTVVAFM
::..: ::. :. : ::.:::::::..: :.
XP_011 KTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFV
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE0 ISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTG
. :::.
XP_011 LCWLPFFLVMPIGTYILKYDVLFWRKGLSVCTRLRERKEIKN
290 300 310 320
>>XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A adrene (317 aa)
initn: 417 init1: 327 opt: 472 Z-score: 425.8 bits: 87.1 E(85289): 5.6e-17
Smith-Waterman score: 478; 32.6% identity (60.8% similar) in 291 aa overlap (16-274:8-288)
10 20 30 40 50
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVK--IPFSPGSRVILYIVFGFGAVLAVFGNLLVMISIL
:. ...:.. : . .. ..: ...: ...:.::.::..:.
XP_016 MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVA
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 HFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYS
..::: :.. ...:: ::.:. ::.::: . : . : ::: ::.. . :: : .
XP_016 CHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYS-GAVFYTGVYDDGL
:.. ::.:::::::.:. :: ::: : . . . : : :. : : .: :
XP_016 SIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF-------GW
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 EELSDALNCIGGCQTVVNQNWVLTDFL-SFFIPTFIMIILYGNIFLVARRQAKKIENTGS
.. . . : :: . ..:: . : ::..: :....: ...::.:... .. .:
XP_016 RQPAPEDETI--CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLK-SGL
170 180 190 200 210 220
240 250 260
pF1KE0 KTESS-SESYKARVAR---------------------------RERKAAKTLGVTVVAFM
::..: ::. :. : ::.:::::::..: :.
XP_016 KTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFV
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE0 ISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTG
. :::.
XP_016 LCWLPFFLVMPIGKKMKKLKVPWPEEGHRRKLTLS
290 300 310
>>XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A adrene (308 aa)
initn: 419 init1: 327 opt: 468 Z-score: 422.5 bits: 86.5 E(85289): 8.6e-17
Smith-Waterman score: 481; 32.5% identity (59.9% similar) in 302 aa overlap (16-285:8-299)
10 20 30 40 50
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVK--IPFSPGSRVILYIVFGFGAVLAVFGNLLVMISIL
:. ...:.. : . .. ..: ...: ...:.::.::..:.
XP_011 MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVA
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 HFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYS
..::: :.. ...:: ::.:. ::.::: . : . : ::: ::.. . :: : .
XP_011 CHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYS-GAVFYTGVYDDGL
:.. ::.:::::::.:. :: ::: : . . . : : :. : : .: :
XP_011 SIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF-------GW
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 EELSDALNCIGGCQTVVNQNWVLTDFL-SFFIPTFIMIILYGNIFLVARRQAKKIENTGS
.. . . : :: . ..:: . : ::..: :....: ...::.:... .. .:
XP_011 RQPAPEDETI--CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLK-SGL
170 180 190 200 210 220
240 250 260
pF1KE0 KTESS-SESYKARVAR---------------------------RERKAAKTLGVTVVAFM
::..: ::. :. : ::.:::::::..: :.
XP_011 KTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFV
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE0 ISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTG
. :::. . :: :
XP_011 LCWLPFFLVMPIDEQRGEGSGFSTHH
290 300
345 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 03:31:54 2016 done: Sat Nov 5 03:31:55 2016
Total Scan time: 6.320 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]