Result of FASTA (omim) for
pF1KE0801
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0801, 356 aa
1>>>pF1KE0801 356 - 356 aa - 356 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0659+/-0.000544; mu= 17.7875+/- 0.033
mean_var=119.6491+/-30.013, 0's: 0 Z-trim(108.3): 587 B-trim: 978 in 1/48
Lambda= 0.117252
statistics sampled from 15620 (16344) to 15620 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.539), E-opt: 0.2 (0.192), width: 16
Scan time: 6.860
The best scores are: opt bits E(85289)
NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 2349 409.5 5.9e-114
NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 2292 399.8 4.7e-111
XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 807 148.6 2e-35
NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 807 148.6 2e-35
NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 758 140.4 6.2e-33
XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 758 140.4 6.3e-33
XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 758 140.4 6.7e-33
NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 758 140.4 6.7e-33
NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 751 139.2 1.4e-32
NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 749 138.8 1.8e-32
NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 749 138.8 1.8e-32
NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 749 138.8 1.8e-32
NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 749 138.9 1.8e-32
XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 740 137.3 5.1e-32
NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 740 137.3 5.1e-32
XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 738 137.0 6.4e-32
XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 738 137.0 6.4e-32
XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 738 137.0 6.4e-32
NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 738 137.0 6.4e-32
NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 738 137.0 6.4e-32
XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 738 137.0 6.4e-32
NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 737 136.8 7.2e-32
NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 737 136.8 7.2e-32
NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 723 134.5 3.9e-31
NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 716 133.2 8.4e-31
NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 716 133.2 8.4e-31
NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 716 133.2 8.4e-31
NP_116743 (OMIM: 601613) C-X-C chemokine receptor ( 327) 712 132.5 1.3e-30
NP_001707 (OMIM: 601613) C-X-C chemokine receptor ( 372) 712 132.6 1.4e-30
NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 710 132.3 1.7e-30
XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 702 130.9 4.4e-30
NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 702 130.9 4.4e-30
NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 700 130.5 5.5e-30
NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 697 130.1 8e-30
NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 697 130.1 8e-30
NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 688 128.5 2.3e-29
NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315) 681 127.2 4.7e-29
NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 679 127.0 6.4e-29
NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 679 127.0 6.4e-29
NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 679 127.0 6.6e-29
NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 679 127.0 6.6e-29
XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 679 127.1 7e-29
XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 679 127.1 7e-29
NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 677 126.6 8.1e-29
XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 677 126.6 8.1e-29
XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 677 126.6 8.1e-29
NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 677 126.6 8.1e-29
NP_848540 (OMIM: 606065) atypical chemokine recept ( 350) 676 126.5 9e-29
NP_057641 (OMIM: 606065) atypical chemokine recept ( 350) 676 126.5 9e-29
NP_006555 (OMIM: 605163) C-X-C chemokine receptor ( 342) 674 126.1 1.1e-28
>>NP_001008540 (OMIM: 162643,193670) C-X-C chemokine rec (356 aa)
initn: 2349 init1: 2349 opt: 2349 Z-score: 2166.9 bits: 409.5 E(85289): 5.9e-114
Smith-Waterman score: 2349; 100.0% identity (100.0% similar) in 356 aa overlap (1-356:1-356)
10 20 30 40 50 60
pF1KE0 MSIPLPLLQIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSIPLPLLQIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCC
250 260 270 280 290 300
310 320 330 340 350
pF1KE0 LNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
310 320 330 340 350
>>NP_003458 (OMIM: 162643,193670) C-X-C chemokine recept (352 aa)
initn: 2292 init1: 2292 opt: 2292 Z-score: 2114.8 bits: 399.8 E(85289): 4.7e-111
Smith-Waterman score: 2292; 99.4% identity (100.0% similar) in 349 aa overlap (8-356:4-352)
10 20 30 40 50 60
pF1KE0 MSIPLPLLQIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGN
..:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGN
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 GLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 TVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFAN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 VSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 ALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCC
240 250 260 270 280 290
310 320 330 340 350
pF1KE0 LNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
300 310 320 330 340 350
>>XP_016861176 (OMIM: 604836) PREDICTED: C-C chemokine r (360 aa)
initn: 771 init1: 486 opt: 807 Z-score: 757.1 bits: 148.6 E(85289): 2e-35
Smith-Waterman score: 807; 38.0% identity (68.0% similar) in 334 aa overlap (25-356:22-350)
10 20 30 40 50 60
pF1KE0 MSIPLPLLQIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGN
:.:. .:: .: :...::: .::..:. :..::
XP_016 MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGN
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 GLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIY
..:.::. :.:::::: : :.:...:::::..::::. :. .: :: ::: . .:
XP_016 SVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 TVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFAN
:..::..... ..:.:::::::::. : : : : .. ...: :.. ..: :.:..
XP_016 LVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFST
120 130 140 150 160 170
190 200 210 220 230
pF1KE0 VSEADDRYICDRFYP--NDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQK
.. : : . : :. ... ..::..: ..: :: .:: :.: :...:
XP_016 CYTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 RKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFH
::.: ... :.. : :: : . ..... ::.. : : :: . :. ::.::: :
XP_016 NKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVL-QDCTFERYLDYAIQATETLAFVH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 CCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
::::::.: ::: ::. . : .. :: : .: . : . :... :::. .:
XP_016 CCLNPIIYFFLGEKFRKYILQ-LFKTCRG--LFVLCQYC-GLLQIYSADTPSSSYTQSTM
300 310 320 330 340 350
XP_016 DHDLHDAL
360
>>NP_005499 (OMIM: 604836) C-C chemokine receptor type 4 (360 aa)
initn: 771 init1: 486 opt: 807 Z-score: 757.1 bits: 148.6 E(85289): 2e-35
Smith-Waterman score: 807; 38.0% identity (68.0% similar) in 334 aa overlap (25-356:22-350)
10 20 30 40 50 60
pF1KE0 MSIPLPLLQIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGN
:.:. .:: .: :...::: .::..:. :..::
NP_005 MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGN
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 GLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIY
..:.::. :.:::::: : :.:...:::::..::::. :. .: :: ::: . .:
NP_005 SVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 TVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFAN
:..::..... ..:.:::::::::. : : : : .. ...: :.. ..: :.:..
NP_005 LVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFST
120 130 140 150 160 170
190 200 210 220 230
pF1KE0 VSEADDRYICDRFYP--NDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQK
.. : : . : :. ... ..::..: ..: :: .:: :.: :...:
NP_005 CYTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 RKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFH
::.: ... :.. : :: : . ..... ::.. : : :: . :. ::.::: :
NP_005 NKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVL-QDCTFERYLDYAIQATETLAFVH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 CCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
::::::.: ::: ::. . : .. :: : .: . : . :... :::. .:
NP_005 CCLNPIIYFFLGEKFRKYILQ-LFKTCRG--LFVLCQYC-GLLQIYSADTPSSSYTQSTM
300 310 320 330 340 350
NP_005 DHDLHDAL
360
>>NP_001495 (OMIM: 300574) C-X-C chemokine receptor type (368 aa)
initn: 730 init1: 456 opt: 758 Z-score: 712.2 bits: 140.4 E(85289): 6.2e-33
Smith-Waterman score: 758; 35.2% identity (68.2% similar) in 352 aa overlap (7-353:19-357)
10 20 30 40
pF1KE0 MSIPLPLLQIYTSDNYTEEMGSGDYDS--MKEPCFREENANFNKIFLP
::. ..: . ..: .. :: . :: .. . ::.. :::
NP_001 MVLEVSDHQVLNDAEVAALLENFSS---SYDYGENESDSCCTSPPCPQDFSLNFDRAFLP
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 TIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANW
..::..:: :..::: : :. .. : :: . :::.::: :.:.:::.:::::...:
NP_001 ALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQW
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 YFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWI
::. :::.. .....:.:...:.:: ::.:::: :::::. : .. ..::
NP_001 VFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 PALLLTIPDFIFANVSEADDRYI---CDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCY
::...::::: . .. :.: :. .:. . .... ....:..:: .:. ::
NP_001 LCLLFALPDFIFLS-AHHDERLNATHCQYNFPQ-VGRTALRVLQLVAGFLLPLLVMAYCY
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 CIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENT
:.. : :.:... .:.. .:....:: :: ::.. . .: .. : . ..: :.
NP_001 AHILAVLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESR
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE0 VHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSS
: :.: .:...::::::.::::.:.::. : :.. ..:: . .
NP_001 VDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLL--------LRLGCPNQRGLQRQ
300 310 320 330 340
350
pF1KE0 VSTESESSSFHSS
:. ..::.
NP_001 PSSSRRDSSWSETSEASYSGL
350 360
>>XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemokine (378 aa)
initn: 730 init1: 456 opt: 758 Z-score: 712.1 bits: 140.4 E(85289): 6.3e-33
Smith-Waterman score: 758; 35.2% identity (68.2% similar) in 352 aa overlap (7-353:29-367)
10 20 30
pF1KE0 MSIPLPLLQIYTSDNYTEEMGSGDYDS--MKEPCFREE
::. ..: . ..: .. :: . :: ..
XP_005 MPGLAHSPGSPQGWVSDHQVLNDAEVAALLENFSS---SYDYGENESDSCCTSPPCPQDF
10 20 30 40 50
40 50 60 70 80 90
pF1KE0 NANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLP
. ::.. :::..::..:: :..::: : :. .. : :: . :::.::: :.:.:::
XP_005 SLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLP
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE0 FWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLA
.:::::...: ::. :::.. .....:.:...:.:: ::.:::: :::::. :
XP_005 LWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPAR
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 EKVVYVGVWIPALLLTIPDFIFANVSEADDRYI---CDRFYPNDLWVVVFQFQHIMVGLI
.. ..:: ::...::::: . .. :.: :. .:. . .... ....:..
XP_005 VTLTCLAVWGLCLLFALPDFIFLS-AHHDERLNATHCQYNFPQ-VGRTALRVLQLVAGFL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE0 LPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEI
:: .:. :: :.. : :.:... .:.. .:....:: :: ::.. . .: .. :
XP_005 LPLLVMAYCYAHILAVLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE0 IKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKIL
. ..: :. : :.: .:...::::::.::::.:.::. : :..
XP_005 LARNCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLL--------LRLG
300 310 320 330 340
340 350
pF1KE0 SKGKRGGHSSVSTESESSSFHSS
..:: . . :. ..::.
XP_005 CPNQRGLQRQPSSSRRDSSWSETSEASYSGL
350 360 370
>>XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemokine (415 aa)
initn: 730 init1: 456 opt: 758 Z-score: 711.7 bits: 140.4 E(85289): 6.7e-33
Smith-Waterman score: 758; 35.2% identity (68.2% similar) in 352 aa overlap (7-353:66-404)
10 20 30
pF1KE0 MSIPLPLLQIYTSDNYTEEMGSGDYDS--MKEPCFR
::. ..: . ..: .. :: . :: .
XP_016 LPGLYTAPSSPFPPSQVSDHQVLNDAEVAALLENFSS---SYDYGENESDSCCTSPPCPQ
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE0 EENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVIT
. . ::.. :::..::..:: :..::: : :. .. : :: . :::.::: :.:.:
XP_016 DFSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLT
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE0 LPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKL
::.:::::...: ::. :::.. .....:.:...:.:: ::.:::: :::::. :
XP_016 LPLWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPP
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE0 LAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYI---CDRFYPNDLWVVVFQFQHIMVG
.. ..:: ::...::::: . .. :.: :. .:. . .... ....:
XP_016 ARVTLTCLAVWGLCLLFALPDFIFLS-AHHDERLNATHCQYNFPQ-VGRTALRVLQLVAG
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE0 LILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILL
..:: .:. :: :.. : :.:... .:.. .:....:: :: ::.. . .: .. :
XP_016 FLLPLLVMAYCYAHILAVLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDL
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE0 EIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLK
. ..: :. : :.: .:...::::::.::::.:.::. : :.
XP_016 GALARNCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLL--------LR
340 350 360 370 380
340 350
pF1KE0 ILSKGKRGGHSSVSTESESSSFHSS
. ..:: . . :. ..::.
XP_016 LGCPNQRGLQRQPSSSRRDSSWSETSEASYSGL
390 400 410
>>NP_001136269 (OMIM: 300574) C-X-C chemokine receptor t (415 aa)
initn: 730 init1: 456 opt: 758 Z-score: 711.7 bits: 140.4 E(85289): 6.7e-33
Smith-Waterman score: 758; 35.2% identity (68.2% similar) in 352 aa overlap (7-353:66-404)
10 20 30
pF1KE0 MSIPLPLLQIYTSDNYTEEMGSGDYDS--MKEPCFR
::. ..: . ..: .. :: . :: .
NP_001 LPGLYTAPSSPFPPSQVSDHQVLNDAEVAALLENFSS---SYDYGENESDSCCTSPPCPQ
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE0 EENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVIT
. . ::.. :::..::..:: :..::: : :. .. : :: . :::.::: :.:.:
NP_001 DFSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLT
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE0 LPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKL
::.:::::...: ::. :::.. .....:.:...:.:: ::.:::: :::::. :
NP_001 LPLWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPP
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE0 LAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYI---CDRFYPNDLWVVVFQFQHIMVG
.. ..:: ::...::::: . .. :.: :. .:. . .... ....:
NP_001 ARVTLTCLAVWGLCLLFALPDFIFLS-AHHDERLNATHCQYNFPQ-VGRTALRVLQLVAG
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE0 LILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILL
..:: .:. :: :.. : :.:... .:.. .:....:: :: ::.. . .: .. :
NP_001 FLLPLLVMAYCYAHILAVLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDL
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE0 EIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLK
. ..: :. : :.: .:...::::::.::::.:.::. : :.
NP_001 GALARNCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLL--------LR
340 350 360 370 380
340 350
pF1KE0 ILSKGKRGGHSSVSTESESSSFHSS
. ..:: . . :. ..::.
NP_001 LGCPNQRGLQRQPSSSRRDSSWSETSEASYSGL
390 400 410
>>NP_000625 (OMIM: 146929,609423) C-X-C chemokine recept (350 aa)
initn: 673 init1: 391 opt: 751 Z-score: 706.1 bits: 139.2 E(85289): 1.4e-32
Smith-Waterman score: 751; 37.6% identity (68.8% similar) in 330 aa overlap (2-323:3-327)
10 20 30 40 50
pF1KE0 MSIPLPLLQIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVG
.: : . . . :.: : .: : ::. : . ..:: . :...:: ...:
NP_000 MSNITDPQMWDFDDLNFTG-MPPADED--YSPCMLE-TETLNKYVVIIAYALVFLLSLLG
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 NGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVI
:.::.::. :.. ::.:: : :.:..:::::..:::.::.. : .: ::.::::.: ..
NP_000 NSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 YTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFA
::.::..:.:: ::.:::::::::: . .. :. : : .: : .. :..: :.:
NP_000 KEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLV-KFVCLGCWGLSMNLSLPFFLFR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 NVSEADDRY-ICDRFYPNDL--WVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGH
.. . .. .: . :: : .:... :.:.: .:.: :: . . : ...
NP_000 QAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 QKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAF
::..:... ..: :. ::::: . . :... ..:...:: .:.. . .. :: :.:
NP_000 QKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 FHCCLNPILYAFLGAKF-----KTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESS
.: :::::.:::.: .: : :.:.:.:
NP_000 LHSCLNPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL
300 310 320 330 340 350
pF1KE0 SFHSS
>>NP_001288645 (OMIM: 600242) C-C chemokine receptor typ (372 aa)
initn: 620 init1: 424 opt: 749 Z-score: 704.0 bits: 138.8 E(85289): 1.8e-32
Smith-Waterman score: 749; 33.5% identity (71.0% similar) in 355 aa overlap (7-355:17-371)
10 20 30 40 50
pF1KE0 MSIPLPLLQIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYS
: : ..:.: . . :: .. : ... ::. ::: .::
NP_001 MKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWFLPIMYS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 IIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGN
:: ..:..:::::.:.. : :.:..::: : :.:.:::.::..:::::: .:. .: ::
NP_001 IICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGV
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 FLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRK--LLAEKVVYVGVWIPA
.:: . .:: ....:..:.: ::.:::.:::.:....: : :: :. ::.:: :
NP_001 HFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 LLLTIPDFIFANV--SEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCII
.:.::....... : ... . :. . . ...: ....:...: ... :: .:
NP_001 TVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVI
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 ISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHK
: : .... .. ::.:. . ....:.. ::: . .. ..: .. ::. . ..
NP_001 IRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 WISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSS--LKILSKGKRGGHSSV
..: .:: .::.::.::::.:.::... . . ... :. :. :. .. .::.
NP_001 AYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSM
310 320 330 340 350 360
350
pF1KE0 STESESSSFHSS
:.:.:... :
NP_001 SVEAETTTTFSP
370
356 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 03:12:31 2016 done: Sat Nov 5 03:12:32 2016
Total Scan time: 6.860 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]