Result of FASTA (omim) for
pF1KE0684
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0684, 399 aa
1>>>pF1KE0684 399 - 399 aa - 399 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5436+/-0.000451; mu= 11.0780+/- 0.028
mean_var=137.2955+/-29.778, 0's: 0 Z-trim(114.3): 247 B-trim: 434 in 1/49
Lambda= 0.109458
statistics sampled from 23730 (24095) to 23730 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.283), width: 16
Scan time: 6.530
The best scores are: opt bits E(85289)
NP_004218 (OMIM: 605081) cytohesin-3 [Homo sapiens ( 399) 2681 435.4 1.2e-121
NP_059430 (OMIM: 182115) cytohesin-1 isoform 2 [Ho ( 397) 2279 371.9 1.5e-102
XP_016880825 (OMIM: 182115) PREDICTED: cytohesin-1 ( 399) 2278 371.7 1.7e-102
NP_004753 (OMIM: 182115) cytohesin-1 isoform 1 [Ho ( 398) 2267 370.0 5.7e-102
NP_004219 (OMIM: 602488) cytohesin-2 isoform 2 [Ho ( 399) 2224 363.2 6.3e-100
XP_006723535 (OMIM: 602488) PREDICTED: cytohesin-2 ( 421) 2221 362.7 9.1e-100
NP_059431 (OMIM: 602488) cytohesin-2 isoform 1 [Ho ( 400) 2212 361.3 2.3e-99
XP_016880826 (OMIM: 182115) PREDICTED: cytohesin-1 ( 380) 2179 356.1 8.4e-98
XP_006723536 (OMIM: 602488) PREDICTED: cytohesin-2 ( 394) 2106 344.6 2.5e-94
XP_016880827 (OMIM: 182115) PREDICTED: cytohesin-1 ( 338) 2075 339.6 6.8e-93
XP_011523779 (OMIM: 182115) PREDICTED: cytohesin-1 ( 339) 2063 337.7 2.5e-92
NP_001278948 (OMIM: 182115) cytohesin-1 isoform 3 ( 339) 2063 337.7 2.5e-92
NP_001278947 (OMIM: 182115) cytohesin-1 isoform 3 ( 339) 2063 337.7 2.5e-92
NP_037517 (OMIM: 606514) cytohesin-4 isoform 1 [Ho ( 394) 1994 326.9 5.4e-89
XP_011523777 (OMIM: 182115) PREDICTED: cytohesin-1 ( 322) 1963 321.9 1.4e-87
XP_011523778 (OMIM: 182115) PREDICTED: cytohesin-1 ( 322) 1963 321.9 1.4e-87
XP_011528449 (OMIM: 606514) PREDICTED: cytohesin-4 ( 337) 1850 304.1 3.4e-82
NP_001304953 (OMIM: 606514) cytohesin-4 isoform 2 ( 337) 1850 304.1 3.4e-82
XP_011523780 (OMIM: 182115) PREDICTED: cytohesin-1 ( 235) 1431 237.8 2.1e-62
XP_011528450 (OMIM: 606514) PREDICTED: cytohesin-4 ( 211) 916 156.4 6e-38
XP_011515744 (OMIM: 604141) PREDICTED: brefeldin A (1649) 635 112.9 6e-24
XP_005251193 (OMIM: 604141) PREDICTED: brefeldin A (1800) 635 112.9 6.4e-24
XP_005251192 (OMIM: 604141) PREDICTED: brefeldin A (1843) 635 112.9 6.5e-24
XP_005251191 (OMIM: 604141) PREDICTED: brefeldin A (1849) 635 112.9 6.5e-24
NP_006412 (OMIM: 604141) brefeldin A-inhibited gua (1849) 635 112.9 6.5e-24
XP_005260309 (OMIM: 605371,608097) PREDICTED: bref (1784) 613 109.4 7e-23
NP_006411 (OMIM: 605371,608097) brefeldin A-inhibi (1785) 613 109.4 7e-23
XP_011532617 (OMIM: 610166) PREDICTED: IQ motif an ( 814) 540 97.6 1.2e-19
NP_001317548 (OMIM: 610166) IQ motif and SEC7 doma ( 814) 540 97.6 1.2e-19
NP_055684 (OMIM: 610166) IQ motif and SEC7 domain- ( 963) 540 97.6 1.3e-19
XP_011532614 (OMIM: 610166) PREDICTED: IQ motif an (1006) 540 97.7 1.4e-19
XP_011532613 (OMIM: 610166) PREDICTED: IQ motif an (1006) 540 97.7 1.4e-19
XP_011532616 (OMIM: 610166) PREDICTED: IQ motif an (1006) 540 97.7 1.4e-19
XP_011532615 (OMIM: 610166) PREDICTED: IQ motif an (1006) 540 97.7 1.4e-19
XP_011532612 (OMIM: 610166) PREDICTED: IQ motif an (1030) 540 97.7 1.4e-19
NP_001127854 (OMIM: 610166) IQ motif and SEC7 doma (1114) 540 97.7 1.5e-19
XP_011532610 (OMIM: 610166) PREDICTED: IQ motif an (1128) 540 97.7 1.5e-19
XP_011532609 (OMIM: 610166) PREDICTED: IQ motif an (1129) 540 97.7 1.5e-19
XP_011532608 (OMIM: 610166) PREDICTED: IQ motif an (1129) 540 97.7 1.5e-19
XP_011532607 (OMIM: 610166) PREDICTED: IQ motif an (1132) 540 97.7 1.5e-19
XP_016863071 (OMIM: 610166) PREDICTED: IQ motif an (1207) 540 97.7 1.6e-19
XP_016863070 (OMIM: 610166) PREDICTED: IQ motif an (1212) 540 97.7 1.6e-19
XP_011532606 (OMIM: 610166) PREDICTED: IQ motif an (1222) 540 97.7 1.6e-19
NP_056047 (OMIM: 612118) IQ motif and SEC7 domain- ( 759) 527 95.5 4.7e-19
XP_011519263 (OMIM: 612118) PREDICTED: IQ motif an ( 879) 527 95.5 5.2e-19
XP_016874799 (OMIM: 612118) PREDICTED: IQ motif an (1041) 527 95.6 5.9e-19
XP_016874800 (OMIM: 612118) PREDICTED: IQ motif an (1041) 527 95.6 5.9e-19
XP_011519262 (OMIM: 612118) PREDICTED: IQ motif an (1062) 527 95.6 5.9e-19
XP_011519261 (OMIM: 612118) PREDICTED: IQ motif an (1062) 527 95.6 5.9e-19
XP_011519260 (OMIM: 612118) PREDICTED: IQ motif an (1063) 527 95.6 5.9e-19
>>NP_004218 (OMIM: 605081) cytohesin-3 [Homo sapiens] (399 aa)
initn: 2681 init1: 2681 opt: 2681 Z-score: 2305.0 bits: 435.4 E(85289): 1.2e-121
Smith-Waterman score: 2681; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:1-399)
10 20 30 40 50 60
pF1KE0 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 PGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRI
310 320 330 340 350 360
370 380 390
pF1KE0 SAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
:::::::::::::::::::::::::::::::::::::::
NP_004 SAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
370 380 390
>>NP_059430 (OMIM: 182115) cytohesin-1 isoform 2 [Homo s (397 aa)
initn: 2309 init1: 2278 opt: 2279 Z-score: 1962.0 bits: 371.9 E(85289): 1.5e-102
Smith-Waterman score: 2279; 84.2% identity (94.0% similar) in 399 aa overlap (1-399:1-395)
10 20 30 40 50 60
pF1KE0 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEE
:.:: . :: ::. :::.:: .:::::.::. ::.::: ::::: .::.:: :.::
NP_059 MEEDDSY----VPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEE
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL
:. :::::.::::::::::::::::::::::::... ::.:::::::::::::.:::::
NP_059 RKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 GERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN
::::::::.::.::::::::.::::::::::::::::::::::::::::::::.::: ::
NP_059 GERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 PGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLY
::::::::::::::::::::::::: ::.::::.:::::::::::.:::::::::::::
NP_059 NGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 DKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRI
:::::::::::::::::::: .:::::::: :..: :::::::::::::::::::.::::
NP_059 DKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRI
300 310 320 330 340 350
370 380 390
pF1KE0 SAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
:::.:::::::.: :::.:::::::.:::.::..... :
NP_059 SAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
360 370 380 390
>>XP_016880825 (OMIM: 182115) PREDICTED: cytohesin-1 iso (399 aa)
initn: 2309 init1: 2278 opt: 2278 Z-score: 1961.1 bits: 371.7 E(85289): 1.7e-102
Smith-Waterman score: 2278; 85.8% identity (95.4% similar) in 388 aa overlap (12-399:10-397)
10 20 30 40 50 60
pF1KE0 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEE
:: ::. :::.:: .:::::.::. ::.::: ::::: .::.:: :.::
XP_016 MVLKTEEEDVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEE
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL
:. :::::.::::::::::::::::::::::::... ::.:::::::::::::.:::::
XP_016 RKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 GERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN
::::::::.::.::::::::.::::::::::::::::::::::::::::::::.::: ::
XP_016 GERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 PGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLY
::::::::::::::::::::::::: ::.::::.:::::::::::.:::::::::::::
XP_016 NGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 DKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRI
:::::::::::::::::::: .:::::::: :..: :::::::::::::::::::.::::
XP_016 DKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRI
300 310 320 330 340 350
370 380 390
pF1KE0 SAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
:::.:::::::.: :::.:::::::.:::.::..... :
XP_016 SAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
360 370 380 390
>>NP_004753 (OMIM: 182115) cytohesin-1 isoform 1 [Homo s (398 aa)
initn: 2280 init1: 1540 opt: 2267 Z-score: 1951.7 bits: 370.0 E(85289): 5.7e-102
Smith-Waterman score: 2267; 84.0% identity (93.8% similar) in 400 aa overlap (1-399:1-396)
10 20 30 40 50 60
pF1KE0 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEE
:.:: . :: ::. :::.:: .:::::.::. ::.::: ::::: .::.:: :.::
NP_004 MEEDDSY----VPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEE
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL
:. :::::.::::::::::::::::::::::::... ::.:::::::::::::.:::::
NP_004 RKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 GERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN
::::::::.::.::::::::.::::::::::::::::::::::::::::::::.::: ::
NP_004 GERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 PGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLY
::::::::::::::::::::::::: ::.::::.:::::::::::.:::::::::::::
NP_004 NGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLY
180 190 200 210 220 230
250 260 270 280 290
pF1KE0 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGG-RVKTWKRRWFILTDNCLYYFEYT
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
NP_004 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 TDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYR
::::::::::::::::::::: .:::::::: :..: :::::::::::::::::::.:::
NP_004 TDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYR
300 310 320 330 340 350
360 370 380 390
pF1KE0 ISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
::::.:::::::.: :::.:::::::.:::.::..... :
NP_004 ISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
360 370 380 390
>>NP_004219 (OMIM: 602488) cytohesin-2 isoform 2 [Homo s (399 aa)
initn: 2221 init1: 2221 opt: 2224 Z-score: 1915.0 bits: 363.2 E(85289): 6.3e-100
Smith-Waterman score: 2224; 80.9% identity (94.0% similar) in 397 aa overlap (3-399:2-394)
10 20 30 40 50 60
pF1KE0 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEE
::: : : ::. ::: :: .:::::.::. .:.::. :..:.:.:...: . :
NP_004 MEDGVYE----PPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEANEG
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL
::: :::...::::::::::::::::::.::.:::..::..:.:::::::::::.:::::
NP_004 SKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 GERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN
:::.:.:. ::.:::.::::.::::::::::::::::::::::::::::::::.::::::
NP_004 GEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 PGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLY
::::::::::::::::.::::::::: :::::: :::.:::::::::::::::::::::
NP_004 PGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
.::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 DKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRI
::::::::::::::::::.::::::::::: :..:::.:::::::::::::::::.::::
NP_004 DKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRI
300 310 320 330 340 350
370 380 390
pF1KE0 SAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
:::. :::.::.:::.:..: ::::.:::.::.::. ::
NP_004 SAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP
360 370 380 390
>>XP_006723535 (OMIM: 602488) PREDICTED: cytohesin-2 iso (421 aa)
initn: 2221 init1: 2221 opt: 2221 Z-score: 1912.1 bits: 362.7 E(85289): 9.1e-100
Smith-Waterman score: 2221; 81.9% identity (95.3% similar) in 387 aa overlap (13-399:30-416)
10 20 30 40
pF1KE0 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKY
: ::. ::: :: .:::::.::. .:.::.
XP_006 MDPVVRITRSPATSPVMESENQGLSPLPKPPDLTPEERMELENIRRRKQELLVEIQRLRE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 EIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQ
:..:.:.:...: . : ::: :::...::::::::::::::::::.::.:::..::..:.
XP_006 ELSEAMSEVEGLEANEGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIAR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 FLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQ
:::::::::::.::::::::.:.:. ::.:::.::::.::::::::::::::::::::::
XP_006 FLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 KIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNR
::::::::::.::::::::::::::::::::::.::::::::: :::::: :::.::::
XP_006 KIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNR
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 GINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKR
:::::::::::::::::.::.:::::::::::::::::::::::::::::::::::::::
XP_006 GINEGGDLPEELLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKR
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 RWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACK
:::::::::::::::::::::::::::::::::::.::::::::::: :..:::.:::::
XP_006 RWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACK
310 320 330 340 350 360
350 360 370 380 390
pF1KE0 TEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
::::::::::::.:::::::. :::.::.:::.:..: ::::.:::.::.::. ::
XP_006 TEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQ
370 380 390 400 410 420
XP_006 P
>>NP_059431 (OMIM: 602488) cytohesin-2 isoform 1 [Homo s (400 aa)
initn: 1481 init1: 1481 opt: 2212 Z-score: 1904.7 bits: 361.3 E(85289): 2.3e-99
Smith-Waterman score: 2212; 80.7% identity (93.7% similar) in 398 aa overlap (3-399:2-395)
10 20 30 40 50 60
pF1KE0 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEE
::: : : ::. ::: :: .:::::.::. .:.::. :..:.:.:...: . :
NP_059 MEDGVYE----PPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEANEG
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL
::: :::...::::::::::::::::::.::.:::..::..:.:::::::::::.:::::
NP_059 SKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 GERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN
:::.:.:. ::.:::.::::.::::::::::::::::::::::::::::::::.::::::
NP_059 GEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 PGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLY
::::::::::::::::.::::::::: :::::: :::.:::::::::::::::::::::
NP_059 PGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLY
180 190 200 210 220 230
250 260 270 280 290
pF1KE0 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGG-RVKTWKRRWFILTDNCLYYFEYT
.::.:::::::::::::::::::::::::::::::: :::::::::::::::::::::::
NP_059 DSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 TDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYR
:::::::::::::::::::.::::::::::: :..:::.:::::::::::::::::.:::
NP_059 TDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYR
300 310 320 330 340 350
360 370 380 390
pF1KE0 ISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
::::. :::.::.:::.:..: ::::.:::.::.::. ::
NP_059 ISAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP
360 370 380 390 400
>>XP_016880826 (OMIM: 182115) PREDICTED: cytohesin-1 iso (380 aa)
initn: 2178 init1: 2178 opt: 2179 Z-score: 1876.9 bits: 356.1 E(85289): 8.4e-98
Smith-Waterman score: 2179; 85.0% identity (93.7% similar) in 380 aa overlap (1-380:1-376)
10 20 30 40 50 60
pF1KE0 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEE
:.:: . :: ::. :::.:: .:::::.::. ::.::: ::::: .::.:: :.::
XP_016 MEEDDSY----VPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEE
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL
:. :::::.::::::::::::::::::::::::... ::.:::::::::::::.:::::
XP_016 RKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 GERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN
::::::::.::.::::::::.::::::::::::::::::::::::::::::::.::: ::
XP_016 GERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 PGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLY
::::::::::::::::::::::::: ::.::::.:::::::::::.:::::::::::::
XP_016 NGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 DKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRI
:::::::::::::::::::: .:::::::: :..: :::::::::::::::::::.::::
XP_016 DKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRI
300 310 320 330 340 350
370 380 390
pF1KE0 SAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
:::.:::::::.: :: ..:
XP_016 SAPTPEEKEEWIKCIKFQVSPGEP
360 370 380
>>XP_006723536 (OMIM: 602488) PREDICTED: cytohesin-2 iso (394 aa)
initn: 2120 init1: 1481 opt: 2106 Z-score: 1814.4 bits: 344.6 E(85289): 2.5e-94
Smith-Waterman score: 2106; 82.7% identity (95.3% similar) in 365 aa overlap (13-376:30-394)
10 20 30 40
pF1KE0 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKY
: ::. ::: :: .:::::.::. .:.::.
XP_006 MDPVVRITRSPATSPVMESENQGLSPLPKPPDLTPEERMELENIRRRKQELLVEIQRLRE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 EIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQ
:..:.:.:...: . : ::: :::...::::::::::::::::::.::.:::..::..:.
XP_006 ELSEAMSEVEGLEANEGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIAR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 FLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQ
:::::::::::.::::::::.:.:. ::.:::.::::.::::::::::::::::::::::
XP_006 FLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 KIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNR
::::::::::.::::::::::::::::::::::.::::::::: :::::: :::.::::
XP_006 KIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNR
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 GINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGG-RVKTWK
:::::::::::::::::.::.:::::::::::::::::::::::::::::::: ::::::
XP_006 GINEGGDLPEELLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 RRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKAC
::::::::::::::::::::::::::::::::::::.::::::::::: :..:::.::::
XP_006 RRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKAC
310 320 330 340 350 360
350 360 370 380 390
pF1KE0 KTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
:::::::::::::.:::::::. :::.::.:::.
XP_006 KTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQ
370 380 390
>>XP_016880827 (OMIM: 182115) PREDICTED: cytohesin-1 iso (338 aa)
initn: 2106 init1: 2075 opt: 2075 Z-score: 1788.8 bits: 339.6 E(85289): 6.8e-93
Smith-Waterman score: 2075; 89.3% identity (97.3% similar) in 335 aa overlap (65-399:2-336)
40 50 60 70 80 90
pF1KE0 IDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLL
:::::.::::::::::::::::::::::::
XP_016 MQRNKQVAMGRKKFNMDPKKGIQFLIENDLL
10 20 30
100 110 120 130 140 150
pF1KE0 QSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLW
... ::.:::::::::::::.:::::::::::::.::.::::::::.:::::::::::::
XP_016 KNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLW
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 SFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPT
:::::::::::::::::::.::: :: ::::::::::::::::::::::::: ::.::::
XP_016 SFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE0 AERFIAMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKL
.:::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE0 GGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSH
:::::::::::::::::::::::::::::::::::::::::::::: .:::::::: :..
XP_016 GGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDN
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE0 KGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRR
: :::::::::::::::::::.:::::::.:::::::.: :::.:::::::.:::.::..
XP_016 KDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKK
280 290 300 310 320 330
pF1KE0 IANKK
... :
XP_016 VSSTKRH
399 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:14:45 2016 done: Sat Nov 5 04:14:47 2016
Total Scan time: 6.530 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]