Result of FASTA (omim) for
pF1KE0546
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0546, 297 aa
1>>>pF1KE0546 297 - 297 aa - 297 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1750+/-0.000315; mu= 16.0793+/- 0.020
mean_var=60.5711+/-12.208, 0's: 0 Z-trim(115.6): 11 B-trim: 346 in 1/52
Lambda= 0.164794
statistics sampled from 26178 (26189) to 26178 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.307), width: 16
Scan time: 6.470
The best scores are: opt bits E(85289)
NP_001257412 (OMIM: 180370) thiosulfate sulfurtran ( 297) 2032 491.2 1e-138
NP_003303 (OMIM: 180370) thiosulfate sulfurtransfe ( 297) 2032 491.2 1e-138
NP_001123989 (OMIM: 602496) 3-mercaptopyruvate sul ( 297) 1278 312.0 9.2e-85
NP_001013454 (OMIM: 602496) 3-mercaptopyruvate sul ( 297) 1278 312.0 9.2e-85
XP_005261667 (OMIM: 602496) PREDICTED: 3-mercaptop ( 297) 1278 312.0 9.2e-85
NP_066949 (OMIM: 602496) 3-mercaptopyruvate sulfur ( 317) 1278 312.0 9.7e-85
XP_011528497 (OMIM: 602496) PREDICTED: 3-mercaptop ( 237) 815 201.9 1e-51
XP_011528498 (OMIM: 602496) PREDICTED: 3-mercaptop ( 294) 812 201.2 2e-51
>>NP_001257412 (OMIM: 180370) thiosulfate sulfurtransfer (297 aa)
initn: 2032 init1: 2032 opt: 2032 Z-score: 2611.6 bits: 491.2 E(85289): 1e-138
Smith-Waterman score: 2032; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297)
10 20 30 40 50 60
pF1KE0 MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDL
190 200 210 220 230 240
250 260 270 280 290
pF1KE0 SQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
250 260 270 280 290
>>NP_003303 (OMIM: 180370) thiosulfate sulfurtransferase (297 aa)
initn: 2032 init1: 2032 opt: 2032 Z-score: 2611.6 bits: 491.2 E(85289): 1e-138
Smith-Waterman score: 2032; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297)
10 20 30 40 50 60
pF1KE0 MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDL
190 200 210 220 230 240
250 260 270 280 290
pF1KE0 SQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
250 260 270 280 290
>>NP_001123989 (OMIM: 602496) 3-mercaptopyruvate sulfurt (297 aa)
initn: 1180 init1: 691 opt: 1278 Z-score: 1642.8 bits: 312.0 E(85289): 9.2e-85
Smith-Waterman score: 1278; 59.5% identity (83.1% similar) in 296 aa overlap (1-295:1-295)
10 20 30 40 50
pF1KE0 MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGT-REARKEYLERHVPGASFF
:. : :::::..:.::..:. . : :..:::::: : :.::.:. :::.:::.::
NP_001 MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 DIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVF
::..: : .:::. :::. ::::.::::.. ::::.::. : . :::::::::.:
NP_001 DIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 GHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQL
::..::.:.::.:.::... :..: :.: :: :.: :: ...::::.. :::::.:::.
NP_001 GHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 VDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVD
::::. ::: :::::: :.. ::: :.::.:: :::...:.::.:::.: ::: ::::
NP_001 VDSRATGRFRGTEPEPRD-GIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVD
190 200 210 220 230
240 250 260 270 280 290
pF1KE0 LSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
::.::.::: .:::::::::.::::::::: .::::: ::. :: ::. .:.:...
NP_001 LSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRGKTH
240 250 260 270 280 290
>>NP_001013454 (OMIM: 602496) 3-mercaptopyruvate sulfurt (297 aa)
initn: 1180 init1: 691 opt: 1278 Z-score: 1642.8 bits: 312.0 E(85289): 9.2e-85
Smith-Waterman score: 1278; 59.5% identity (83.1% similar) in 296 aa overlap (1-295:1-295)
10 20 30 40 50
pF1KE0 MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGT-REARKEYLERHVPGASFF
:. : :::::..:.::..:. . : :..:::::: : :.::.:. :::.:::.::
NP_001 MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 DIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVF
::..: : .:::. :::. ::::.::::.. ::::.::. : . :::::::::.:
NP_001 DIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 GHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQL
::..::.:.::.:.::... :..: :.: :: :.: :: ...::::.. :::::.:::.
NP_001 GHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 VDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVD
::::. ::: :::::: :.. ::: :.::.:: :::...:.::.:::.: ::: ::::
NP_001 VDSRATGRFRGTEPEPRD-GIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVD
190 200 210 220 230
240 250 260 270 280 290
pF1KE0 LSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
::.::.::: .:::::::::.::::::::: .::::: ::. :: ::. .:.:...
NP_001 LSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRGKTH
240 250 260 270 280 290
>>XP_005261667 (OMIM: 602496) PREDICTED: 3-mercaptopyruv (297 aa)
initn: 1180 init1: 691 opt: 1278 Z-score: 1642.8 bits: 312.0 E(85289): 9.2e-85
Smith-Waterman score: 1278; 59.5% identity (83.1% similar) in 296 aa overlap (1-295:1-295)
10 20 30 40 50
pF1KE0 MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGT-REARKEYLERHVPGASFF
:. : :::::..:.::..:. . : :..:::::: : :.::.:. :::.:::.::
XP_005 MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 DIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVF
::..: : .:::. :::. ::::.::::.. ::::.::. : . :::::::::.:
XP_005 DIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 GHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQL
::..::.:.::.:.::... :..: :.: :: :.: :: ...::::.. :::::.:::.
XP_005 GHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 VDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVD
::::. ::: :::::: :.. ::: :.::.:: :::...:.::.:::.: ::: ::::
XP_005 VDSRATGRFRGTEPEPRD-GIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVD
190 200 210 220 230
240 250 260 270 280 290
pF1KE0 LSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
::.::.::: .:::::::::.::::::::: .::::: ::. :: ::. .:.:...
XP_005 LSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRGKTH
240 250 260 270 280 290
>>NP_066949 (OMIM: 602496) 3-mercaptopyruvate sulfurtran (317 aa)
initn: 1180 init1: 691 opt: 1278 Z-score: 1642.3 bits: 312.0 E(85289): 9.7e-85
Smith-Waterman score: 1278; 59.5% identity (83.1% similar) in 296 aa overlap (1-295:21-315)
10 20 30 40
pF1KE0 MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPG
:. : :::::..:.::..:. . : :..:::::: :
NP_066 MAEPGSRESETRARSPSVAAMASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPK
10 20 30 40 50 60
50 60 70 80 90
pF1KE0 T-REARKEYLERHVPGASFFDIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVY
:.::.:. :::.:::.::::..: : .:::. :::. ::::.::::.. ::::.:
NP_066 LGRDARREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIY
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 DGEHLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDR
:. : . :::::::::.:::..::.:.::.:.::... :..: :.: :: :.: ::
NP_066 DASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDP
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 SLLKTYEQVLENLESKRFQLVDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTE
...::::.. :::::.:::.::::. ::: :::::: :.. ::: :.::.:: :::..
NP_066 AFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRD-GIEPGHIPGTVNIPFTDFLSQ
190 200 210 220 230
220 230 240 250 260 270
pF1KE0 DGFEKGPEELRALFQTKKVDLSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEW
.:.::.:::.: ::: ::::::.::.::: .:::::::::.::::::::: .::::: ::
NP_066 EGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEW
240 250 260 270 280 290
280 290
pF1KE0 FRRAPPESRVSQGKSEKA
. :: ::. .:.:...
NP_066 YMRARPEDVISEGRGKTH
300 310
>>XP_011528497 (OMIM: 602496) PREDICTED: 3-mercaptopyruv (237 aa)
initn: 805 init1: 687 opt: 815 Z-score: 1049.4 bits: 201.9 E(85289): 1e-51
Smith-Waterman score: 815; 56.2% identity (81.1% similar) in 201 aa overlap (1-200:21-221)
10 20 30 40
pF1KE0 MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPG
:. : :::::..:.::..:. . : :..:::::: :
XP_011 MAEPGSRESETRARSPSVAAMASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPK
10 20 30 40 50 60
50 60 70 80 90
pF1KE0 T-REARKEYLERHVPGASFFDIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVY
:.::.:. :::.:::.::::..: : .:::. :::. ::::.::::.. ::::.:
XP_011 LGRDARREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIY
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 DGEHLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDR
:. : . :::::::::.:::..::.:.::.:.::... :..: :.: :: :.: ::
XP_011 DASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDP
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 SLLKTYEQVLENLESKRFQLVDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTE
...::::.. :::::.:::.::::. ::: :::::: .:.
XP_011 AFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDAGVQWRNLGSPQPPPPGFK
190 200 210 220 230
220 230 240 250 260 270
pF1KE0 DGFEKGPEELRALFQTKKVDLSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEW
>>XP_011528498 (OMIM: 602496) PREDICTED: 3-mercaptopyruv (294 aa)
initn: 828 init1: 691 opt: 812 Z-score: 1044.1 bits: 201.2 E(85289): 2e-51
Smith-Waterman score: 812; 53.7% identity (78.0% similar) in 214 aa overlap (1-213:1-214)
10 20 30 40 50
pF1KE0 MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGT-REARKEYLERHVPGASFF
:. : :::::..:.::..:. . : :..:::::: : :.::.:. :::.:::.::
XP_011 MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 DIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVF
::..: : .:::. :::. ::::.::::.. ::::.::. : . :::::::::.:
XP_011 DIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 GHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQL
::..::.:.::.:.::... :..: :.: :: :.: :: ...::::.. :::::.:::.
XP_011 GHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 VDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVD
::::. ::: :::::: . : :.. :.
XP_011 VDSRATGRFRGTEPEPRDGNAGEGGRRSSGARPLRPEQCPGLDLSFIFLIYLAFISFPFF
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 LSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
XP_011 FPFLPFPFPPFPLFPTLAFFSQGLALPPRLECSGTIMAHCSLNLLGSGDPPRSA
250 260 270 280 290
297 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:02:32 2016 done: Thu Nov 3 00:02:33 2016
Total Scan time: 6.470 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]