FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0529, 214 aa
  1>>>pF1KE0529 214 - 214 aa - 214 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4043+/-0.000525; mu= 12.1427+/- 0.032
 mean_var=53.8341+/-11.491, 0's: 0 Z-trim(106.1): 39  B-trim: 432 in 1/48
 Lambda= 0.174802
 statistics sampled from 14212 (14220) to 14212 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.49), E-opt: 0.2 (0.167), width:  16
 Scan time:  4.500

The best scores are:                                      opt bits E(85289)
NP_006845 (OMIM: 609024) ER lumen protein-retainin ( 212) 1093 284.2 1.1e-76
NP_006792 (OMIM: 131235) ER lumen protein-retainin ( 212) 1054 274.3   1e-73
NP_001094073 (OMIM: 609024) ER lumen protein-retai ( 186)  548 146.7 2.3e-35


>>NP_006845 (OMIM: 609024) ER lumen protein-retaining re  (212 aa)
 initn: 1093 init1: 1093 opt: 1093  Z-score: 1497.6  bits: 284.2 E(85289): 1.1e-76
Smith-Waterman score: 1093; 76.8% identity (92.4% similar) in 211 aa overlap (1-211:1-211)

               10        20        30        40        50        60
pF1KE0 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYN
       ::.::. :::::: :...:: :::... : :::::::.:::::::::::::::.:::.::
NP_006 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 TVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILW
       : :::..: :.:.:::.:: ::. :.:...::::.:::.::: ::::: :..:. :::::
NP_006 TSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIA
       :::::::::::::::::::::::::::::::::::::::::::.::: :.  :.:.: ::
NP_006 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIA
              130       140       150       160       170       180

              190       200       210    
pF1KE0 VVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPMPI
       ::.::::::.::::::::.::::::::::::   
NP_006 VVAGVVQTILYCDFFYLYITKVLKGKKLSLPA  
              190       200       210    

>>NP_006792 (OMIM: 131235) ER lumen protein-retaining re  (212 aa)
 initn: 1054 init1: 1054 opt: 1054  Z-score: 1444.5  bits: 274.3 E(85289): 1e-73
Smith-Waterman score: 1054; 73.0% identity (92.9% similar) in 211 aa overlap (1-211:1-211)

               10        20        30        40        50        60
pF1KE0 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYN
       ::.::.:::::::::.:::: :::.:. : :::::::.:::.:::.::::::::.::.::
NP_006 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 TVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILW
       : ::::.. :...::..::.::. :.:...::::.:::.::.  :.:: :..:: :::::
NP_006 TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIA
       :::::::::::::::::.::::::::::.:::: ::.::.::: ::: ::. :.:.: ::
NP_006 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA
              130       140       150       160       170       180

              190       200       210    
pF1KE0 VVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPMPI
       .:.:.:::..::::::::.::::::::::::   
NP_006 IVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA  
              190       200       210    

>>NP_001094073 (OMIM: 609024) ER lumen protein-retaining  (186 aa)
 initn: 548 init1: 548 opt: 548  Z-score: 755.8  bits: 146.7 E(85289): 2.3e-35
Smith-Waterman score: 548; 67.5% identity (89.7% similar) in 117 aa overlap (1-117:1-117)

               10        20        30        40        50        60
pF1KE0 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYN
       ::.::. :::::: :...:: :::... : :::::::.:::::::::::::::.:::.::
NP_001 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 TVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILW
       : :::..: :.:.:::.:: ::. :.:...::::.:::.::: ::::: :..:. ::   
NP_001 TSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEYSR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIA
                                                                   
NP_001 ERSSVCQHKCQRPSPASVLQGARTEFLPQQRHKMLDTENQKLNSFVADSHQWLCKNAEEK
              130       140       150       160       170       180




214 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 01:32:49 2016 done: Thu Nov  3 01:32:50 2016
 Total Scan time:  4.500 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]