Result of FASTA (omim) for
pF1KE0508
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0508, 168 aa
1>>>pF1KE0508 168 - 168 aa - 168 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9549+/-0.000269; mu= 14.6537+/- 0.017
mean_var=62.4539+/-12.448, 0's: 0 Z-trim(120.3): 10 B-trim: 25 in 1/50
Lambda= 0.162291
statistics sampled from 35424 (35434) to 35424 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.415), width: 16
Scan time: 6.180
The best scores are: opt bits E(85289)
NP_056519 (OMIM: 614637) desumoylating isopeptidas ( 168) 1130 272.1 3e-73
XP_005261628 (OMIM: 614637) PREDICTED: desumoylati ( 209) 920 223.0 2.3e-58
XP_011542507 (OMIM: 614638) PREDICTED: desumoylati ( 187) 188 51.6 8.1e-07
NP_057160 (OMIM: 614638) desumoylating isopeptidas ( 194) 188 51.6 8.3e-07
XP_011542505 (OMIM: 614638) PREDICTED: desumoylati ( 211) 188 51.6 8.9e-07
XP_011542509 (OMIM: 614638) PREDICTED: desumoylati ( 154) 154 43.5 0.00017
NP_001284675 (OMIM: 614638) desumoylating isopepti ( 161) 154 43.6 0.00018
XP_011542508 (OMIM: 614638) PREDICTED: desumoylati ( 178) 154 43.6 0.00019
>>NP_056519 (OMIM: 614637) desumoylating isopeptidase 1 (168 aa)
initn: 1130 init1: 1130 opt: 1130 Z-score: 1436.1 bits: 272.1 E(85289): 3e-73
Smith-Waterman score: 1130; 100.0% identity (100.0% similar) in 168 aa overlap (1-168:1-168)
10 20 30 40 50 60
pF1KE0 MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSGGISSCPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSGGISSCPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GGTLLGPPDSVVDVGSTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GGTLLGPPDSVVDVGSTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLT
70 80 90 100 110 120
130 140 150 160
pF1KE0 GRKIPSYITDLPSEVLSTPFGQALRPLLDSIQIQPPGGSSVGRPNGQS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GRKIPSYITDLPSEVLSTPFGQALRPLLDSIQIQPPGGSSVGRPNGQS
130 140 150 160
>>XP_005261628 (OMIM: 614637) PREDICTED: desumoylating i (209 aa)
initn: 920 init1: 920 opt: 920 Z-score: 1169.0 bits: 223.0 E(85289): 2.3e-58
Smith-Waterman score: 920; 100.0% identity (100.0% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KE0 MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSGGISSCPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSGGISSCPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GGTLLGPPDSVVDVGSTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGTLLGPPDSVVDVGSTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLT
70 80 90 100 110 120
130 140 150 160
pF1KE0 GRKIPSYITDLPSEVLSTPFGQALRPLLDSIQIQPPGGSSVGRPNGQS
::::::::::::::::::
XP_005 GRKIPSYITDLPSEVLSTTVFNRCFLQEHSAARSVLMCPKPWKSLAGHHPGSIPRKDTTP
130 140 150 160 170 180
>>XP_011542507 (OMIM: 614638) PREDICTED: desumoylating i (187 aa)
initn: 152 init1: 110 opt: 188 Z-score: 243.4 bits: 51.6 E(85289): 8.1e-07
Smith-Waterman score: 188; 32.2% identity (61.2% similar) in 121 aa overlap (35-146:20-139)
10 20 30 40 50
pF1KE0 NLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGS-----GGISSCP
:..:..: :. :: .:. .::
XP_011 MKPQTLVYWMNEYTSSIGIGVFHSGIEVYGREFAYGGHPYPFSGIFEIS
10 20 30 40
60 70 80 90 100 110
pF1KE0 PGG-TLLGPP---DSVVDVGSTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEV
::. . :: .: .:::. :. . . . ::. ..:.::.:...::: ::. .
XP_011 PGNASELGETFKFKEAVVLGSTDFLEDDIEKIVEELGKE-YKGNAYHLMHKNCNHFSSAL
50 60 70 80 90 100
120 130 140 150 160
pF1KE0 AQFLTGRKIPSYITDLPSEVLSTPFGQALRPLLDSIQIQPPGGSSVGRPNGQS
...: :..:: .:. : :: :. :
XP_011 SEILCGKEIPRWINRLAYFSSCIPFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAA
110 120 130 140 150 160
XP_011 SASVASTAAGSRPGRHTKL
170 180
>>NP_057160 (OMIM: 614638) desumoylating isopeptidase 2 (194 aa)
initn: 167 init1: 110 opt: 188 Z-score: 243.2 bits: 51.6 E(85289): 8.3e-07
Smith-Waterman score: 188; 32.2% identity (61.2% similar) in 121 aa overlap (35-146:27-146)
10 20 30 40 50
pF1KE0 NLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGS-----GGISSCP
:..:..: :. :: .:. .::
NP_057 MGANQLVVLNVYDMYWMNEYTSSIGIGVFHSGIEVYGREFAYGGHPYPFSGIFEIS
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 PGG-TLLGPP---DSVVDVGSTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEV
::. . :: .: .:::. :. . . . ::. ..:.::.:...::: ::. .
NP_057 PGNASELGETFKFKEAVVLGSTDFLEDDIEKIVEELGKE-YKGNAYHLMHKNCNHFSSAL
60 70 80 90 100 110
120 130 140 150 160
pF1KE0 AQFLTGRKIPSYITDLPSEVLSTPFGQALRPLLDSIQIQPPGGSSVGRPNGQS
...: :..:: .:. : :: :. :
NP_057 SEILCGKEIPRWINRLAYFSSCIPFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAA
120 130 140 150 160 170
NP_057 SASVASTAAGSRPGRHTKL
180 190
>>XP_011542505 (OMIM: 614638) PREDICTED: desumoylating i (211 aa)
initn: 152 init1: 110 opt: 188 Z-score: 242.6 bits: 51.6 E(85289): 8.9e-07
Smith-Waterman score: 188; 32.2% identity (61.2% similar) in 121 aa overlap (35-146:44-163)
10 20 30 40 50
pF1KE0 NLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGS-----GGISSCP
:..:..: :. :: .:. .::
XP_011 YLEILVVLLSYTLKTTFQYWMNEYTSSIGIGVFHSGIEVYGREFAYGGHPYPFSGIFEIS
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE0 PGG-TLLGPP---DSVVDVGSTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEV
::. . :: .: .:::. :. . . . ::. ..:.::.:...::: ::. .
XP_011 PGNASELGETFKFKEAVVLGSTDFLEDDIEKIVEELGKE-YKGNAYHLMHKNCNHFSSAL
80 90 100 110 120 130
120 130 140 150 160
pF1KE0 AQFLTGRKIPSYITDLPSEVLSTPFGQALRPLLDSIQIQPPGGSSVGRPNGQS
...: :..:: .:. : :: :. :
XP_011 SEILCGKEIPRWINRLAYFSSCIPFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAA
140 150 160 170 180 190
XP_011 SASVASTAAGSRPGRHTKL
200 210
>>XP_011542509 (OMIM: 614638) PREDICTED: desumoylating i (154 aa)
initn: 152 init1: 110 opt: 154 Z-score: 201.6 bits: 43.5 E(85289): 0.00017
Smith-Waterman score: 154; 31.6% identity (61.2% similar) in 98 aa overlap (49-146:13-106)
20 30 40 50 60 70
pF1KE0 GLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSGGISSCPPGGTLLGPPDSVVDVGSTE
. .: ::. : . : .: .:::.
XP_011 MKPQTLVYWMNEYTSSIGIGVFHSGIEVYG---RAVVLGSTD
10 20 30
80 90 100 110 120 130
pF1KE0 VTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLTGRKIPSYITDLPSEVLST
:. . . . ::. ..:.::.:...::: ::. ....: :..:: .:. :
XP_011 FLEDDIEKIVEELGKE-YKGNAYHLMHKNCNHFSSALSEILCGKEIPRWINRLAYFSSCI
40 50 60 70 80 90
140 150 160
pF1KE0 PFGQALRPLLDSIQIQPPGGSSVGRPNGQS
:: :. :
XP_011 PFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAASASVASTAAGSRPGRHTKL
100 110 120 130 140 150
>>NP_001284675 (OMIM: 614638) desumoylating isopeptidase (161 aa)
initn: 167 init1: 110 opt: 154 Z-score: 201.3 bits: 43.6 E(85289): 0.00018
Smith-Waterman score: 154; 31.6% identity (61.2% similar) in 98 aa overlap (49-146:20-113)
20 30 40 50 60 70
pF1KE0 GLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSGGISSCPPGGTLLGPPDSVVDVGSTE
. .: ::. : . : .: .:::.
NP_001 MGANQLVVLNVYDMYWMNEYTSSIGIGVFHSGIEVYG---RAVVLGSTD
10 20 30 40
80 90 100 110 120 130
pF1KE0 VTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLTGRKIPSYITDLPSEVLST
:. . . . ::. ..:.::.:...::: ::. ....: :..:: .:. :
NP_001 FLEDDIEKIVEELGKE-YKGNAYHLMHKNCNHFSSALSEILCGKEIPRWINRLAYFSSCI
50 60 70 80 90 100
140 150 160
pF1KE0 PFGQALRPLLDSIQIQPPGGSSVGRPNGQS
:: :. :
NP_001 PFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAASASVASTAAGSRPGRHTKL
110 120 130 140 150 160
>>XP_011542508 (OMIM: 614638) PREDICTED: desumoylating i (178 aa)
initn: 152 init1: 110 opt: 154 Z-score: 200.7 bits: 43.6 E(85289): 0.00019
Smith-Waterman score: 154; 31.6% identity (61.2% similar) in 98 aa overlap (49-146:37-130)
20 30 40 50 60 70
pF1KE0 GLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSGGISSCPPGGTLLGPPDSVVDVGSTE
. .: ::. : . : .: .:::.
XP_011 KKIAQLNYLEILVVLLSYTLKTTFQYWMNEYTSSIGIGVFHSGIEVYG---RAVVLGSTD
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE0 VTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLTGRKIPSYITDLPSEVLST
:. . . . ::. ..:.::.:...::: ::. ....: :..:: .:. :
XP_011 FLEDDIEKIVEELGKE-YKGNAYHLMHKNCNHFSSALSEILCGKEIPRWINRLAYFSSCI
70 80 90 100 110 120
140 150 160
pF1KE0 PFGQALRPLLDSIQIQPPGGSSVGRPNGQS
:: :. :
XP_011 PFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAASASVASTAAGSRPGRHTKL
130 140 150 160 170
168 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 03:36:47 2016 done: Thu Nov 3 03:36:48 2016
Total Scan time: 6.180 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]