Result of FASTA (omim) for
pF1KE0502
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0502, 211 aa
1>>>pF1KE0502 211 - 211 aa - 211 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7956+/-0.000317; mu= 16.1994+/- 0.020
mean_var=57.3430+/-11.590, 0's: 0 Z-trim(115.9): 36 B-trim: 33 in 1/52
Lambda= 0.169369
statistics sampled from 26722 (26758) to 26722 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.314), width: 16
Scan time: 6.280
The best scores are: opt bits E(85289)
NP_004067 (OMIM: 123630,609741) beta-crystallin B3 ( 211) 1479 369.1 2.9e-102
XP_011528204 (OMIM: 123630,609741) PREDICTED: beta ( 267) 1479 369.2 3.5e-102
NP_001878 (OMIM: 600929,611544) beta-crystallin B1 ( 252) 855 216.7 2.7e-56
XP_011528201 (OMIM: 600929,611544) PREDICTED: beta ( 252) 855 216.7 2.7e-56
XP_011528202 (OMIM: 123620,601547) PREDICTED: beta ( 205) 840 213.0 2.9e-55
XP_006724204 (OMIM: 123620,601547) PREDICTED: beta ( 205) 840 213.0 2.9e-55
NP_000487 (OMIM: 123620,601547) beta-crystallin B2 ( 205) 840 213.0 2.9e-55
XP_016884088 (OMIM: 123630,609741) PREDICTED: beta ( 169) 741 188.7 4.7e-48
NP_005199 (OMIM: 123610,600881) beta-crystallin A3 ( 215) 580 149.4 4e-36
XP_016879687 (OMIM: 123610,600881) PREDICTED: beta ( 316) 581 149.8 4.6e-36
NP_001877 (OMIM: 123631,610425) beta-crystallin A4 ( 196) 508 131.8 7.3e-31
XP_006724203 (OMIM: 123631,610425) PREDICTED: beta ( 201) 508 131.8 7.5e-31
XP_016884087 (OMIM: 123631,610425) PREDICTED: beta ( 207) 508 131.8 7.6e-31
NP_476434 (OMIM: 115900,600836) beta-crystallin A2 ( 197) 494 128.4 7.9e-30
NP_476435 (OMIM: 115900,600836) beta-crystallin A2 ( 197) 494 128.4 7.9e-30
XP_011514138 (OMIM: 609603) PREDICTED: gamma-cryst ( 295) 443 116.1 6.2e-26
XP_005250009 (OMIM: 609603) PREDICTED: gamma-cryst ( 182) 439 114.9 8.2e-26
NP_060011 (OMIM: 116100,123730) beta-crystallin S ( 178) 416 109.3 4e-24
NP_066269 (OMIM: 123680,604307) gamma-crystallin C ( 174) 400 105.4 5.8e-23
XP_011508964 (OMIM: 123680,604307) PREDICTED: gamm ( 174) 400 105.4 5.8e-23
XP_016858891 (OMIM: 123670,615188) PREDICTED: gamm ( 177) 392 103.5 2.3e-22
NP_005201 (OMIM: 123670,615188) gamma-crystallin B ( 175) 386 102.0 6.3e-22
NP_055432 (OMIM: 123660) gamma-crystallin A [Homo ( 174) 382 101.0 1.2e-21
XP_011514139 (OMIM: 609603) PREDICTED: gamma-cryst ( 260) 381 100.9 2e-21
NP_008822 (OMIM: 115700,123690) gamma-crystallin D ( 174) 361 95.9 4.3e-20
NP_653328 (OMIM: 609603) gamma-crystallin N isofor ( 182) 305 82.2 5.9e-16
XP_016867262 (OMIM: 609603) PREDICTED: gamma-cryst ( 125) 251 68.9 4.1e-12
NP_001295221 (OMIM: 609603) gamma-crystallin N iso ( 125) 251 68.9 4.1e-12
XP_016865822 (OMIM: 601797) PREDICTED: absent in m (1544) 185 53.5 2.2e-06
NP_001615 (OMIM: 601797) absent in melanoma 1 prot (1723) 185 53.5 2.4e-06
XP_005266896 (OMIM: 601797) PREDICTED: absent in m (2131) 185 53.5 2.9e-06
>>NP_004067 (OMIM: 123630,609741) beta-crystallin B3 [Ho (211 aa)
initn: 1479 init1: 1479 opt: 1479 Z-score: 1956.9 bits: 369.1 E(85289): 2.9e-102
Smith-Waterman score: 1479; 99.5% identity (99.5% similar) in 211 aa overlap (1-211:1-211)
10 20 30 40 50 60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_004 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
130 140 150 160 170 180
190 200 210
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
:::::::::::::::::::::::::::::::
NP_004 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
190 200 210
>>XP_011528204 (OMIM: 123630,609741) PREDICTED: beta-cry (267 aa)
initn: 1479 init1: 1479 opt: 1479 Z-score: 1955.4 bits: 369.2 E(85289): 3.5e-102
Smith-Waterman score: 1479; 99.5% identity (99.5% similar) in 211 aa overlap (1-211:57-267)
10 20 30
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYE
::::::::::::::::::::::::::::::
XP_011 PLAKTGESADGRGSSVLPEATATARGVPGEMAEQHGAPEQAAAGKSHGDLGGSYKVILYE
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE0 LENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWD
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE0 AWSNSRDSDSLLSLRPLNIDSPDHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVAS
:::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_011 AWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVAS
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE0 VRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPS
210 220 230 240 250 260
pF1KE0 S
:
XP_011 S
>>NP_001878 (OMIM: 600929,611544) beta-crystallin B1 [Ho (252 aa)
initn: 855 init1: 855 opt: 855 Z-score: 1131.7 bits: 216.7 E(85289): 2.7e-56
Smith-Waterman score: 855; 56.9% identity (85.6% similar) in 188 aa overlap (22-209:57-244)
10 20 30 40 50
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDS
:.:.....:::::::.: :.:.:: .:.:
NP_001 PPAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADR
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE0 LLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDS
...: :: : .:::.:::. ::::.:.::::.::::..::.: :: :.:.::...:.
NP_001 GFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDA
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE0 PDHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQY
.::. :::. :.: .:: ::.::::..::.:::.::.. .::::::..::::: ::
NP_001 QEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQY
150 160 170 180 190 200
180 190 200 210
pF1KE0 VFERGEYRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
..: :..:::::: : :::.::.::.::..:: .: ::
NP_001 LLEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
210 220 230 240 250
>>XP_011528201 (OMIM: 600929,611544) PREDICTED: beta-cry (252 aa)
initn: 855 init1: 855 opt: 855 Z-score: 1131.7 bits: 216.7 E(85289): 2.7e-56
Smith-Waterman score: 855; 56.9% identity (85.6% similar) in 188 aa overlap (22-209:57-244)
10 20 30 40 50
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDS
:.:.....:::::::.: :.:.:: .:.:
XP_011 PPAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADR
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE0 LLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDS
...: :: : .:::.:::. ::::.:.::::.::::..::.: :: :.:.::...:.
XP_011 GFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDA
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE0 PDHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQY
.::. :::. :.: .:: ::.::::..::.:::.::.. .::::::..::::: ::
XP_011 QEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQY
150 160 170 180 190 200
180 190 200 210
pF1KE0 VFERGEYRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
..: :..:::::: : :::.::.::.::..:: .: ::
XP_011 LLEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
210 220 230 240 250
>>XP_011528202 (OMIM: 123620,601547) PREDICTED: beta-cry (205 aa)
initn: 937 init1: 807 opt: 840 Z-score: 1113.2 bits: 213.0 E(85289): 2.9e-55
Smith-Waterman score: 840; 53.8% identity (83.0% similar) in 212 aa overlap (1-211:1-205)
10 20 30 40 50 60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
:: .: :. ::: .. . :.:..: :::::. ::.. ::.: .. .::.::.
XP_011 MASDH----QTQAGKPQSL---NPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVL
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
:..:::...:. .:::::.:::.:::::.:..:: .::: ::::...:: .::. :.:
XP_011 VQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
:: :.:.::::.::::::. :::.:..:.:::. .::::::..::::: ::..:.:.:.
XP_011 NPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKD
120 130 140 150 160 170
190 200 210
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRF-PSS
... : .::.::::::::..::.:: : ::.
XP_011 SSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN
180 190 200
>>XP_006724204 (OMIM: 123620,601547) PREDICTED: beta-cry (205 aa)
initn: 937 init1: 807 opt: 840 Z-score: 1113.2 bits: 213.0 E(85289): 2.9e-55
Smith-Waterman score: 840; 53.8% identity (83.0% similar) in 212 aa overlap (1-211:1-205)
10 20 30 40 50 60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
:: .: :. ::: .. . :.:..: :::::. ::.. ::.: .. .::.::.
XP_006 MASDH----QTQAGKPQSL---NPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVL
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
:..:::...:. .:::::.:::.:::::.:..:: .::: ::::...:: .::. :.:
XP_006 VQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
:: :.:.::::.::::::. :::.:..:.:::. .::::::..::::: ::..:.:.:.
XP_006 NPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKD
120 130 140 150 160 170
190 200 210
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRF-PSS
... : .::.::::::::..::.:: : ::.
XP_006 SSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN
180 190 200
>>NP_000487 (OMIM: 123620,601547) beta-crystallin B2 [Ho (205 aa)
initn: 937 init1: 807 opt: 840 Z-score: 1113.2 bits: 213.0 E(85289): 2.9e-55
Smith-Waterman score: 840; 53.8% identity (83.0% similar) in 212 aa overlap (1-211:1-205)
10 20 30 40 50 60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
:: .: :. ::: .. . :.:..: :::::. ::.. ::.: .. .::.::.
NP_000 MASDH----QTQAGKPQSL---NPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVL
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
:..:::...:. .:::::.:::.:::::.:..:: .::: ::::...:: .::. :.:
NP_000 VQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
:: :.:.::::.::::::. :::.:..:.:::. .::::::..::::: ::..:.:.:.
NP_000 NPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKD
120 130 140 150 160 170
190 200 210
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRF-PSS
... : .::.::::::::..::.:: : ::.
NP_000 SSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN
180 190 200
>>XP_016884088 (OMIM: 123630,609741) PREDICTED: beta-cry (169 aa)
initn: 741 init1: 741 opt: 741 Z-score: 983.7 bits: 188.7 E(85289): 4.7e-48
Smith-Waterman score: 741; 100.0% identity (100.0% similar) in 109 aa overlap (1-109:57-165)
10 20 30
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYE
::::::::::::::::::::::::::::::
XP_016 PLAKTGESADGRGSSVLPEATATARGVPGEMAEQHGAPEQAAAGKSHGDLGGSYKVILYE
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE0 LENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWD
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE0 AWSNSRDSDSLLSLRPLNIDSPDHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVAS
:::::::::::::::::::
XP_016 AWSNSRDSDSLLSLRPLNIVGWL
150 160
>>NP_005199 (OMIM: 123610,600881) beta-crystallin A3 [Ho (215 aa)
initn: 572 init1: 307 opt: 580 Z-score: 769.6 bits: 149.4 E(85289): 4e-36
Smith-Waterman score: 598; 43.5% identity (74.0% similar) in 200 aa overlap (9-198:17-214)
10 20 30 40 50
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSL
..: .. . :.:: .:. .:. ::::::: :... ::....
NP_005 METQAEQQELETLPTTKMAQTNPTPGSLG-PWKITIYDQENFQGKRMEFTSSCPNVSERS
10 20 30 40 50
60 70 80 90 100
pF1KE0 LEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWS--NSRDSDSLLSLRPL-NI
...: :..:::: :...: .: :.::.::.:.:::::::: :. . :.:.::. .
NP_005 FDNVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 DSPDHKLHLFENPAFSGRKMEIVDDDVPSLWAHG-FQDRVASVRAINGTWVGYEFPGYRG
. . :. .::. : ::. :: .:: ::: : : :...:.:.. .:.:: :..:::::
NP_005 NHKESKMTIFEKENFIGRQWEI-SDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRG
120 130 140 150 160 170
170 180 190 200 210
pF1KE0 RQYVFE----RGEYRHWNEWD--ASQPQLQSVRRIRDQKWHKRGRFPSS
::..: :.:.:: :: :. :.::.:::.
NP_005 YQYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
180 190 200 210
>>XP_016879687 (OMIM: 123610,600881) PREDICTED: beta-cry (316 aa)
initn: 572 init1: 307 opt: 581 Z-score: 768.4 bits: 149.8 E(85289): 4.6e-36
Smith-Waterman score: 599; 42.3% identity (72.6% similar) in 208 aa overlap (1-198:110-315)
10 20 30
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYE
. : . ..: .. . :.:: .:. .:.
XP_016 SCRLQVSFTFQGIPSPPPPPKRPHHSCVLCLPETLPTTKMAQTNPTPGSLG-PWKITIYD
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE0 LENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWD
::::::: :... ::.... ...: :..:::: :...: .: :.::.::.:.:::::
XP_016 QENFQGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWD
140 150 160 170 180 190
100 110 120 130 140
pF1KE0 AWS--NSRDSDSLLSLRPL-NIDSPDHKLHLFENPAFSGRKMEIVDDDVPSLWAHG-FQD
::: :. . :.:.::. . . . :. .::. : ::. :: .:: ::: : : :..
XP_016 AWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEI-SDDYPSLQAMGWFNN
200 210 220 230 240 250
150 160 170 180 190 200
pF1KE0 RVASVRAINGTWVGYEFPGYRGRQYVFE----RGEYRHWNEWD--ASQPQLQSVRRIRDQ
.:.:.. .:.:: :..::::: ::..: :.:.:: :: :. :.::.:::.
XP_016 EVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
260 270 280 290 300 310
210
pF1KE0 KWHKRGRFPSS
211 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 03:55:34 2016 done: Thu Nov 3 03:55:35 2016
Total Scan time: 6.280 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]