Result of FASTA (ccds) for
pF1KE0496
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0496, 252 aa
1>>>pF1KE0496 252 - 252 aa - 252 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6017+/-0.000759; mu= 10.3871+/- 0.046
mean_var=113.2552+/-22.858, 0's: 0 Z-trim(112.9): 16 B-trim: 430 in 1/53
Lambda= 0.120516
statistics sampled from 13545 (13559) to 13545 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.417), width: 16
Scan time: 2.510
The best scores are: opt bits E(32554)
CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 ( 252) 1745 313.3 1e-85
CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 ( 211) 853 158.2 4.3e-39
CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 ( 205) 805 149.8 1.4e-36
CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 ( 215) 659 124.4 6.2e-29
CCDS2429.1 CRYBA2 gene_id:1412|Hs108|chr2 ( 197) 581 110.8 6.9e-25
CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22 ( 196) 557 106.7 1.2e-23
CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 ( 178) 415 82.0 3.1e-16
CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 ( 174) 382 76.2 1.6e-14
CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 ( 174) 378 75.5 2.7e-14
CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 ( 175) 370 74.1 7e-14
CCDS2378.1 CRYGD gene_id:1421|Hs108|chr2 ( 174) 357 71.9 3.3e-13
>>CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 (252 aa)
initn: 1745 init1: 1745 opt: 1745 Z-score: 1652.5 bits: 313.3 E(32554): 1e-85
Smith-Waterman score: 1745; 100.0% identity (100.0% similar) in 252 aa overlap (1-252:1-252)
10 20 30 40 50 60
pF1KE0 MSQAAKASASATVAVNPGPDTKGKGAPPAGTSPSPGTTLAPTTVPITSAKAAELPPGNYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MSQAAKASASATVAVNPGPDTKGKGAPPAGTSPSPGTTLAPTTVPITSAKAAELPPGNYR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YPRWNTWSSSYRSDRLMSFRPIKMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YPRWNTWSSSYRSDRLMSFRPIKMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DRVGSVKVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DRVGSVKVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLE
190 200 210 220 230 240
250
pF1KE0 GSFPVLATEPPK
::::::::::::
CCDS13 GSFPVLATEPPK
250
>>CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 (211 aa)
initn: 853 init1: 853 opt: 853 Z-score: 815.4 bits: 158.2 E(32554): 4.3e-39
Smith-Waterman score: 853; 56.9% identity (85.6% similar) in 188 aa overlap (57-244:22-209)
30 40 50 60 70 80
pF1KE0 PPAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADR
:.:.....:::::::.: :.:.:: .:.:
CCDS13 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDS
10 20 30 40 50
90 100 110 120 130 140
pF1KE0 GFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDA
...: :: : .:::.:::. ::::.:.::::.::::..::.: :: :.:.::...:.
CCDS13 LLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDS
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE0 QEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQY
.::. :::. :.: .:: ::.::::..::.:::.::.. .::::::..::::: ::
CCDS13 PHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQY
120 130 140 150 160 170
210 220 230 240 250
pF1KE0 LLEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
..: :..:::::: : :::.::.::.::..:: .: ::
CCDS13 VFERGEYRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
180 190 200 210
>>CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 (205 aa)
initn: 904 init1: 788 opt: 805 Z-score: 770.5 bits: 149.8 E(32554): 1.4e-36
Smith-Waterman score: 805; 55.9% identity (84.9% similar) in 186 aa overlap (58-243:16-201)
30 40 50 60 70 80
pF1KE0 PAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRG
: ....:: :::::. :..: : :: . :
CCDS13 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETG
10 20 30 40
90 100 110 120 130 140
pF1KE0 FDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQ
... :..:.:::::..::.: .::.:..::::::::..:.:: :.: : :.::::.:.:
CCDS13 VEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQ
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE0 EHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYL
:::: :.:. :: :. .:: ::.::. ..:....:.::.:.:::::::::::::: :::
CCDS13 EHKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYL
110 120 130 140 150 160
210 220 230 240 250
pF1KE0 LEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
:: ::.. ...:: .::.::.::.:: ::: .:.:
CCDS13 LEKGDYKDSSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN
170 180 190 200
>>CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 (215 aa)
initn: 573 init1: 309 opt: 659 Z-score: 633.0 bits: 124.4 E(32554): 6.2e-29
Smith-Waterman score: 676; 48.5% identity (77.0% similar) in 204 aa overlap (43-233:12-214)
20 30 40 50 60
pF1KE0 VAVNPGPDTKGKGAPPAGTSPSPGTTLAPTTVPITSAKAAELPPGN---YRLVVFELENF
:.: :. .. ::. ....... :::
CCDS11 METQAEQQELETLPTTKMAQTNPTPGSLGPWKITIYDQENF
10 20 30 40
70 80 90 100 110 120
pF1KE0 QGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSS
::.: ::.. : :...:.:: :::. : .: :...:...: :..::::.::::::..::.
CCDS11 QGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 S--YRSDRLMSFRPI-KMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYG-FSDRVGS
: :. .:::::::: . . .: :...:: :: : ::. :: ::: ..: :...:::
CCDS11 SNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEIS-DDYPSLQAMGWFNNEVGS
110 120 130 140 150 160
190 200 210 220 230
pF1KE0 VKVSSGTWVGYQYPGYRGYQYLLE----PGDFRHWNEWG--AFQPQMQSLRRLRDKQWHL
.:..::.:: :::::::::::.:: ::..:: ::: : :.::.::..
CCDS11 MKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
170 180 190 200 210
240 250
pF1KE0 EGSFPVLATEPPK
>>CCDS2429.1 CRYBA2 gene_id:1412|Hs108|chr2 (197 aa)
initn: 401 init1: 210 opt: 581 Z-score: 560.2 bits: 110.8 E(32554): 6.9e-25
Smith-Waterman score: 581; 47.7% identity (75.4% similar) in 195 aa overlap (51-233:3-196)
30 40 50 60 70
pF1KE0 TKGKGAPPAGTSPSPGTTLAPTTVPITSAKAAELP-PGNYRLVVFELENFQGRRAEFSGE
.: : :. :.... :.::::: .. ..
CCDS24 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSD
10 20 30
80 90 100 110 120 130
pF1KE0 CSNLADRG-FDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWS--SSYRSDRL
:.:. .:: . ::::. : : ::::: .:.:..::::::.::::..:: ::. :..:
CCDS24 CANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 MSFRPIK-MDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDR-VGSVKVSSGTWV
.::::. . .. ...:::: ::.: ... :: ::: .:.... :::.:::::.::
CCDS24 LSFRPVLCANHNDSRVTLFEGDNFQGCKFDLV-DDYPSLPSMGWASKDVGSLKVSSGAWV
100 110 120 130 140 150
200 210 220 230 240
pF1KE0 GYQYPGYRGYQYLLE----PGDFRHWNEWG--AFQPQMQSLRRLRDKQWHLEGSFPVLAT
.:::::::::::.:: :.: ..: : : :.::.::..
CCDS24 AYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQSIRRVQH
160 170 180 190
250
pF1KE0 EPPK
>>CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22 (196 aa)
initn: 493 init1: 279 opt: 557 Z-score: 537.7 bits: 106.7 E(32554): 1.2e-23
Smith-Waterman score: 576; 44.4% identity (76.5% similar) in 187 aa overlap (57-233:10-195)
30 40 50 60 70 80
pF1KE0 PPAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADR
: ...::.. ..::::: ::..:: .. .
CCDS13 MTLQCTKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLEL
10 20 30
90 100 110 120 130 140
pF1KE0 GFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTW--SSSYRSDRLMSFRPIK-
::. :::. : .: ::.::...:.:...:::.:::: :..: ...: ..:: ::::
CCDS13 GFETVRSLKVLSGAWVGFEHAGFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAAC
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 MDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYGF-SDRVGSVKVSSGTWVGYQYPGYR
. .. ....:: :: :. :.. :: ::: ..:. ...::: .: ::.:: :.::::
CCDS13 ANHRDSRLTIFEQENFLGKKGELS-DDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYR
100 110 120 130 140 150
210 220 230 240 250
pF1KE0 GYQYLLE----PGDFRHWNEWGAFQP--QMQSLRRLRDKQWHLEGSFPVLATEPPK
:.::.:: ::..:. :::. : :.::.::..
CCDS13 GFQYVLECDHHSGDYKHFREWGSHAPTFQVQSIRRIQQ
160 170 180 190
>>CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 (178 aa)
initn: 492 init1: 185 opt: 415 Z-score: 404.9 bits: 82.0 E(32554): 3.1e-16
Smith-Waterman score: 415; 36.8% identity (67.8% similar) in 174 aa overlap (60-232:7-176)
30 40 50 60 70 80
pF1KE0 GTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRGFD
... .: .:::::: . . .:... ..
CCDS32 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTY-LS
10 20 30
90 100 110 120 130 140
pF1KE0 RVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQ-E
: :: : .: :...:. :: : :.:: .::::... : . .::: : : ... . .
CCDS32 RCNSIKVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMG--LNDRLSSCRAVHLPSGGQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 HKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYLL
.::..:: ..:.:. : .: ::. .. : :: :.:. :. :.::: ::::
CCDS32 YKIQIFEKGDFSGQMYETT-EDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLL
100 110 120 130 140 150
210 220 230 240 250
pF1KE0 EPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
. ..:. .::: .: .::.::.
CCDS32 DKKEYRKPIDWGAASPAVQSFRRIVE
160 170
>>CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 (174 aa)
initn: 350 init1: 174 opt: 382 Z-score: 374.0 bits: 76.2 E(32554): 1.6e-14
Smith-Waterman score: 382; 34.9% identity (64.6% similar) in 175 aa overlap (60-234:3-172)
30 40 50 60 70 80
pF1KE0 GTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRGFD
... .: . :::: : . .: :: :.
CCDS23 MGKITFYEDRAFQGRSYETTTDCPNLQPY-FS
10 20 30
90 100 110 120 130 140
pF1KE0 RVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQEH
: :: : .: :. .:. :..:....:..:::: .. : . : : . : .. :
CCDS23 RCNSIRVESGCWMLYERPNYQGQQYLLRRGEYPDYQQWMGLSDSIRSCCLIPQTVS---H
40 50 60 70 80
150 160 170 180 190 200
pF1KE0 KISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYLLE
.. :.: . :: .:.. .: ::. ... :..: : :: :. :.::: ::::.
CCDS23 RLRLYEREDHKGLMMELS-EDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLR
90 100 110 120 130 140
210 220 230 240 250
pF1KE0 PGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
: ..:. ..:::.. . ::::. :
CCDS23 PQEYRRCQDWGAMDAKAGSLRRVVDLY
150 160 170
>>CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 (174 aa)
initn: 324 init1: 192 opt: 378 Z-score: 370.3 bits: 75.5 E(32554): 2.7e-14
Smith-Waterman score: 378; 35.6% identity (67.2% similar) in 177 aa overlap (60-234:3-172)
30 40 50 60 70 80
pF1KE0 GTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRGFD
... .: ..:::: . ..: :: :.
CCDS33 MGKITFYEDRDFQGRCYNCISDCPNLRVY-FS
10 20 30
90 100 110 120 130 140
pF1KE0 RVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQEH
: :: :..: :. .:. :..:....:..:.:: .. : . :: ..: : : .. :
CCDS33 RCNSIRVDSGCWMLYERPNYQGHQYFLRRGKYPDYQHWMGL--SDSVQSCRIIPHTSS-H
40 50 60 70 80
150 160 170 180 190 200
pF1KE0 KISLFEGANFKGNTIEIQGDDA--PSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYL
:. :.: ...: :. : : : :. .. :..: : :: :..:.::: :::
CCDS33 KLRLYERDDYRGLMSELTDDCACVPELFRL---PEIYSLHVLEGCWVLYEMPNYRGRQYL
90 100 110 120 130 140
210 220 230 240 250
pF1KE0 LEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
:.:::.:....::. . .. ::::. :
CCDS33 LRPGDYRRYHDWGGADAKVGSLRRVTDLY
150 160 170
>>CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 (175 aa)
initn: 357 init1: 189 opt: 370 Z-score: 362.7 bits: 74.1 E(32554): 7e-14
Smith-Waterman score: 370; 33.1% identity (65.7% similar) in 175 aa overlap (60-234:3-173)
30 40 50 60 70 80
pF1KE0 GTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRGFD
... .: . :::: : . .: :: :.
CCDS23 MGKITFYEDRAFQGRSYECTTDCPNLQPY-FS
10 20 30
90 100 110 120 130 140
pF1KE0 RVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQEH
: :: : .: :. .:. :..:....:..:::: .. : . :: . : : . .
CCDS23 RCNSIRVESGCWMIYERPNYQGHQYFLRRGEYPDYQQWMGL--SDSIRSCCLIPPHSGAY
40 50 60 70 80
150 160 170 180 190 200
pF1KE0 KISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYLLE
...... ...:. :. :: :. .. :..: :.:. :..:.::: ::::.
CCDS23 RMKIYDRDELRGQMSELT-DDCISVQDRFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLR
90 100 110 120 130 140
210 220 230 240 250
pF1KE0 PGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
::..:.. .::: . .. ::::. :
CCDS23 PGEYRRFLDWGAPNAKVGSLRRVMDLY
150 160 170
252 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 04:02:18 2016 done: Thu Nov 3 04:02:19 2016
Total Scan time: 2.510 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]